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1 0 0 -1 0 841.90002441 cm q 1 0 0 1 65.65000153 94.18599701 cm q 474.8500061 0 0 -20.80000114 0 20.80000114 cm /X1 Do Q Q /Artifact <</Attached [/Top ] /BBox [90 711.40600586 505.29998779 799.34997559] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 87.94400024 l -90 87.94400024 l h W n BT /FAAAAI 9 Tf 1 0 0 -1 0 9.56900024 Tm 0 g [(       )-1(              )-1(             )-1(       )] TJ /GS1 gs 0 g [-11231( )] TJ ET q 1 0 0 1 0 11.98600006 cm BT 1 0 0 -1 0 42 Tm /GS2 gs 0 g [(       )-1(              )-1(             )-1(              )-1(  )] TJ 1 0 0 -1 414 42 Tm /GS1 gs 0 g [( )] TJ ET Q q 1 0 0 1 0 53.98600006 cm BT 1 0 0 -1 0 8.56900024 Tm /GS2 gs 0 g [(       )-1(              )-1(            )] TJ /GS1 gs 0 g [-9040( )] TJ ET Q q 1 0 0 1 0 64.97200012 cm BT 1 0 0 -1 0 8.56900024 Tm [( )] TJ ET Q q 1 0 0 1 0 75.95800018 cm BT 1 0 0 -1 0 8.56900024 Tm /GS2 gs 0 g [(  )] TJ /FAAABD 9 Tf [-548( )] TJ ET Q Q EMC /Artifact <</Attached [/Bottom ] /BBox [90 49.59999847 505.29998779 60.58599854] /Type /Pagination >> BDC q 1 0 0 1 90 781.31402588 cm -90 0 m 505.29998779 0 l 505.29998779 10.98600006 l -90 10.98600006 l h W n Q EMC q 1 0 0 1 90 54.5359993 cm q 1 0 0 1 225 0 cm q 188.3500061 0 0 -41.45000076 0 41.45000076 cm /X2 Do Q Q Q q 1 0 0 1 90 130.4940033 cm q 1 0 0 1 22 0 cm /P <</MCID 0 >> BDC BT /FAAABH 22 Tf 1 0 0 -1 47.44599915 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [(T)-4(7)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 69.62200165 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABJ 22 Tf 1 0 0 -1 80.62200165 23.67700005 Tm [<0005>-4<0006>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABH 22 Tf 1 0 0 -1 130.29800415 23.67700005 Tm [(R)-4(N)-4(A)] TJ ET EMC /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 22 Tf 1 0 0 -1 169.06199646 23.67700005 Tm [<0009>-4<000A>-4<000B>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAABH 22 Tf 1 0 0 -1 240.82600403 23.67700005 Tm [(2)-4(.)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 263.00201416 23.67700005 Tm [(0)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 22 Tf 1 0 0 -1 279.58999634 23.67700005 Tm [<000F>-4<0010>-4<0011>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAABH 22 Tf 1 0 0 -1 345.85400391 23.67700005 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 31.20000076 cm /P <</MCID 9 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 207.6499939 11.65499973 Tm 1 Tr 0.30000001 w /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 102.23000336 11.65499973 Tm 2 Tr 0 g 0.30000001 w 0 G [<0012>-4<0013>-4<0014>-4<0015>-4<0016>-4<0017>-3<0018>-4<0019>-4<001A>-4<001B>-4<001C>-4<001D>-4<001E>-4<001F>-4<001C>-4<0020>-3<0021>-4<0022>-4<0023>-4<0024>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 313.07000732 11.65499973 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 62.40000153 cm /P <</MCID 12 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 78 cm /P <</Lang (zh-CN) /MCID 13 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr 0 g 0.30000001 w 0 G [<0025>-4<0026>-4<0027>] TJ ET EMC /P <</MCID 14 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 31.62599945 11.65499973 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 93.59999847 cm /P <</MCID 15 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 0 g [(T7)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 10.5 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 17 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 13.125 11.65499973 Tm [<00050006>] TJ ET EMC /P <</MCID 18 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 34.125 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 36.75 11.65499973 Tm [(RNA)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 52.5 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 55.125 11.65499973 Tm [<0009000A000B>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 86.625 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 89.25 11.65499973 Tm [(2.0)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 105 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 107.625 11.65499973 Tm [<00280029002A002B002C002D002E002F003000310032>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 223.125 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 225.75 11.65499973 Tm [(DNA)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 241.5 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 244.125 11.65499973 Tm [<003400350036>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 275.625 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 278.25 11.65499973 Tm [(RNA)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 294 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 296.625 11.65499973 Tm [<0009000A000B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT 1 0 0 -1 328.125 11.65499973 Tm [<001D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT 1 0 0 -1 336.54998779 11.65499973 Tm [<0037>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 347.04998779 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 349.67498779 11.65499973 Tm [(T7)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 360.17498779 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 362.79998779 11.65499973 Tm [<003800390017003A003B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [<003C003D>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 21 27.25500107 Tm [(TAATACGACT)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 73.5 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 76.26300049 27.25500107 Tm [(CACTATAG)] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 118.26300049 27.25500107 Tm [<00400041004200430044004500460036001D004700480049004A003800390017>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 286.26300049 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 289.02600098 27.25500107 Tm [(T7)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 299.52600098 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 302.28900146 27.25500107 Tm [(RNA)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 318.03900146 27.25500107 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 320.80200195 27.25500107 Tm [<0009000A000B004B004C001D004D004E004F>] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT 1 0 0 -1 0 42.85499954 Tm [<005000430032005100440052005300540017001800550056>] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT 1 0 0 -1 126 42.85499954 Tm [<0057>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 131.80000305 42.85499954 Tm [(T7)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 142.30000305 42.85499954 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 144.92500305 42.85499954 Tm [<00050006>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 165.92500305 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 168.55000305 42.85499954 Tm [(RNA)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 184.30000305 42.85499954 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 186.92500305 42.85499954 Tm [<0009000A000B>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 218.42500305 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 221.05000305 42.85499954 Tm [(2.0)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 236.80000305 42.85499954 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 239.42500305 42.85499954 Tm [<004E004F>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 260.42498779 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 263.04998779 42.85499954 Tm [(37-52)] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 289.29998779 42.85499954 Tm [<005B005C005D0052005300540043005E0032001700180055>] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT 1 0 0 -1 0 58.45499802 Tm [<0056>] TJ ET EMC /P <</Lang (zh-CN) /MCID 68 >> BDC BT 1 0 0 -1 10.5 58.45499802 Tm [<001D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT 1 0 0 -1 19.82500076 58.45499802 Tm [<005F0060005100440061>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 72.32499695 58.45499802 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 74.94999695 58.45499802 Tm [(37)] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 85.44999695 58.45499802 Tm [<005B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT 1 0 0 -1 95.94999695 58.45499802 Tm [<001D>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 105.27500153 58.45499802 Tm [(50)] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 115.77500153 58.45499802 Tm [<005B00620063005C005D0052>] TJ ET EMC /P <</Lang (zh-CN) /MCID 76 >> BDC BT 1 0 0 -1 178.7749939 58.45499802 Tm [<001D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT 1 0 0 -1 188.1000061 58.45499802 Tm [<0064006500660067>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 230.1000061 58.45499802 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 232.7250061 58.45499802 Tm [(50%)] TJ ET EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 248.4750061 58.45499802 Tm [<0069006A0032006B0036>] TJ ET EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT 1 0 0 -1 299.79998779 58.45499802 Tm [<003D00480049004A004F006C005100440052006D006B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 82 >> BDC BT 1 0 0 -1 0 74.05500031 Tm [<003600400057>] TJ ET EMC /P <</Lang (zh-CN) /MCID 83 >> BDC BT 1 0 0 -1 31.5 74.05500031 Tm [<006E002A00430051003200620063004500360042006F0020006900520070007100720073003200740075>] TJ ET EMC /P <</Lang (zh-CN) /MCID 84 >> BDC BT 1 0 0 -1 249.6499939 74.05500031 Tm [<0027>] TJ ET EMC /P <</Lang (zh-CN) /MCID 85 >> BDC BT 1 0 0 -1 257.79998779 74.05500031 Tm [<003D>] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 268.29998779 74.05500031 Tm [(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 273.54998779 74.05500031 Tm [<0040007700780079>] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 315.54998779 74.05500031 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 320.79998779 74.05500031 Tm [(GC)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 331.29998779 74.05500031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 336.54998779 74.05500031 Tm [<007A007B007C0043>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 378.54998779 74.05500031 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 383.79998779 74.05500031 Tm [(RNA)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 399.54998779 74.05500031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 95 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 404.79998779 74.05500031 Tm [<0032>] TJ ET EMC /P <</Lang (zh-CN) /MCID 96 >> BDC BT 1 0 0 -1 0 89.65499878 Tm [<00550056005E007D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 97 >> BDC BT 1 0 0 -1 40.82500076 89.65499878 Tm [<007E>] TJ ET EMC /P <</Lang (zh-CN) /MCID 98 >> BDC BT 1 0 0 -1 50.15000153 89.65499878 Tm [<003D>] TJ ET EMC /P <</MCID 99 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 60.65000153 89.65499878 Tm [(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 100 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 65.90000153 89.65499878 Tm [<0040007700780079007F00800081>] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 139.3999939 89.65499878 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 142.0249939 89.65499878 Tm [(RNA)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 157.7749939 89.65499878 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 104 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 160.3999939 89.65499878 Tm [<0032000A008200830084>] TJ ET EMC /P <</Lang (zh-CN) /MCID 105 >> BDC BT 1 0 0 -1 211.7250061 89.65499878 Tm [<007E>] TJ ET EMC /P <</Lang (zh-CN) /MCID 106 >> BDC BT 1 0 0 -1 221.05000305 89.65499878 Tm [<003D>] TJ ET EMC /P <</MCID 107 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 231.55000305 89.65499878 Tm [(3)] TJ ET EMC /P <</Lang (zh-CN) /MCID 108 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 236.80000305 89.65499878 Tm [<0040004F001B001C00850086008700880089001D007700430079008A005500560032>] TJ ET EMC /P <</Lang (zh-CN) /MCID 109 >> BDC BT 1 0 0 -1 0 105.25499725 Tm [<008B0085005E007D007E003D>] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 63 105.25499725 Tm [(4)] TJ ET EMC /P <</Lang (zh-CN) /MCID 111 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 68.25 105.25499725 Tm [<0040008D008E0079>] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 110.25 105.25499725 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 115.5 105.25499725 Tm [(dsRNA)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 141.75 105.25499725 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 115 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 147 105.25499725 Tm [<009100130088003200920082001D009300940079000A0082>] TJ ET EMC /P <</MCID 116 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 273 105.25499725 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 278.25 105.25499725 Tm [(RNA)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 294 105.25499725 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 119 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 299.25 105.25499725 Tm [<003200950096009700360057>] TJ ET EMC /P <</MCID 120 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 362.25 105.25499725 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 202.80000305 cm /P <</MCID 121 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 218.3999939 cm /P <</MCID 122 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 276 90.30000305 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 312 cm /P <</MCID 123 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 327.6000061 cm /P <</Lang (zh-CN) /MCID 124 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr 0 g 0.30000001 w 0 G [<006B>-4<0036>-4<0098>-4<0099>] TJ ET EMC /P <</Lang (zh-CN) /MCID 125 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 41.04700089 11.65499973 Tm 0 Tr [<0027>] TJ ET EMC /P <</Lang (zh-CN) /MCID 126 >> BDC BT 1 0 0 -1 50.42599869 11.65499973 Tm [<004F009A009B006200630017009C0052001D>] TJ ET EMC /P <</MCID 127 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 144.92599487 11.65499973 Tm [(50)] TJ ET EMC /P <</Lang (zh-CN) /MCID 128 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 155.42599487 11.65499973 Tm [<005B>] TJ ET EMC /P <</MCID 129 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 165.92599487 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 171.17599487 11.65499973 Tm [(1)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 176.42599487 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 132 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 181.67599487 11.65499973 Tm [<009D0089009E009F>] TJ ET EMC /P <</MCID 133 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 223.67599487 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 228.92599487 11.65499973 Tm [(1)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 234.17599487 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 239.42599487 11.65499973 Tm [(nmol)] TJ ET EMC /P <</Lang (zh-CN) /MCID 137 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 263.05099487 11.65499973 Tm [<0032>] TJ ET EMC /P <</MCID 138 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 273.55099487 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 278.80099487 11.65499973 Tm [(ATP)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 294.55099487 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 141 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 299.80099487 11.65499973 Tm [<00A500A600A7001E00A8008800A900AA00AB0032000B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 142 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [<007B00980099006100290071006B003600AC00AD0057>] TJ ET EMC /P <</MCID 143 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 115.5 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 120.75 27.25500107 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 358.79998779 cm /P <</MCID 145 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 374.3999939 cm /P <</MCID 146 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 0 g [(1X)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 10.5 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 17.28899956 11.65499973 Tm [(T7)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 27.78899956 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 34.57799911 11.65499973 Tm [(Transcription)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 102.82800293 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 109.61699677 11.65499973 Tm [(Buffer)] TJ ET EMC /P <</Lang (zh-CN) /MCID 153 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 142.65600586 11.65499973 Tm [<0027>] TJ ET EMC /P <</MCID 154 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 154.69500732 11.65499973 Tm [(40)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 165.19500732 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 171.98399353 11.65499973 Tm [(mM)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 182.48399353 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 189.272995 11.65499973 Tm [(Tris)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 210.272995 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 217.06199646 11.65499973 Tm [(\(pH)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 232.81199646 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 239.60099792 11.65499973 Tm [(7.8\),)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 265.85101318 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 272.64001465 11.65499973 Tm [(20)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 283.14001465 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 289.9289856 11.65499973 Tm [(mMNaCl,)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 326.6789856 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 333.46798706 11.65499973 Tm [(18mM)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 354.46798706 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 361.25698853 11.65499973 Tm [(MgCl2,2)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 398.00698853 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 404.79598999 11.65499973 Tm [(mM)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 415.29598999 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [(Spermidine)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 52.5 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 55.72700119 27.25500107 Tm [(HCl,)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 76.72699738 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 79.95400238 27.25500107 Tm [(10)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 90.45400238 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 93.68099976 27.25500107 Tm [(mM)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 104.18099976 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 107.40799713 27.25500107 Tm [(DTT)] TJ ET EMC /P <</Lang (zh-CN) /MCID 183 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 125.78299713 27.25500107 Tm [<000B00C100C200C30027>] TJ ET EMC /P <</MCID 184 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 178.28300476 27.25500107 Tm [(10)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 188.78300476 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 192.00999451 27.25500107 Tm [(mM)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 202.50999451 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 205.73699951 27.25500107 Tm [(Tris-HCl,)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 252.98699951 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 256.21398926 27.25500107 Tm [(0.1)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 271.96398926 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 275.19100952 27.25500107 Tm [(M)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 280.44100952 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 283.66799927 27.25500107 Tm [(NaCl,)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 309.91799927 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 313.14498901 27.25500107 Tm [(1)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 318.39498901 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 321.62200928 27.25500107 Tm [(mM)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 332.12200928 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 335.34899902 27.25500107 Tm [(DTT,)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 356.34899902 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 359.57598877 27.25500107 Tm [(0.1mM)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 385.82598877 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 389.05300903 27.25500107 Tm [(EDTA,)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 415.30300903 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 0 42.85499954 Tm [(50%)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 15.75 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 21 42.85499954 Tm [(Glycerol,)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 68.25 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 73.5 42.85499954 Tm [(0.01%)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 99.75 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 105 42.85499954 Tm [(\(w/v\))] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 131.25 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 136.5 42.85499954 Tm [(Triton)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 168 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 173.25 42.85499954 Tm [(X-100,)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 204.75 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 210 42.85499954 Tm [(pH)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 220.5 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 225.75 42.85499954 Tm [(7.5)] TJ ET EMC /P <</Lang (zh-CN) /MCID 221 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 241.5 42.85499954 Tm [<0057>] TJ ET EMC /P <</MCID 222 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 252 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 257.25 42.85499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 421.20001221 cm /P <</MCID 224 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 436.79998779 cm /P <</Lang (zh-CN) /MCID 225 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr 0 g 0.30000001 w 0 G [<00C1>-4<00C2>-4<0027>] TJ ET EMC /P <</Lang (zh-CN) /MCID 226 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 31.62599945 11.65499973 Tm 0 Tr [<00C90020>] TJ ET EMC /P <</MCID 227 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 52.62599945 11.65499973 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 228 >> BDC BT 1 0 0 -1 68.37599945 11.65499973 Tm [(?] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 78.87599945 11.65499973 Tm [(C)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 84.12599945 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 231 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 89.37599945 11.65499973 Tm [<004E006600C2>] TJ ET EMC /P <</MCID 232 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 120.87599945 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 126.12599945 11.65499973 Tm [(2)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 131.37600708 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 235 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 136.62600708 11.65499973 Tm [<00CB001D00CC0095006200CD00CE00CF0057>] TJ ET EMC /P <</MCID 236 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 231.12600708 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 236.37600708 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 452.3999939 cm /P <</MCID 238 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 468 cm /P <</Lang (zh-CN) /MCID 239 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr 0 g 0.30000001 w 0 G [<0006>-4<00D0>-4<006B>-4<0027>] TJ ET EMC /P <</MCID 240 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 42.16799927 11.65499973 Tm 0 Tr [(75)] TJ ET EMC /P <</Lang (zh-CN) /MCID 241 >> BDC BT 1 0 0 -1 52.66799927 11.65499973 Tm [(?] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 63.16799927 11.65499973 Tm [(C)] TJ ET EMC /P <</Lang (zh-CN) /MCID 243 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 68.41799927 11.65499973 Tm [<001D>] TJ ET EMC /P <</MCID 244 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 78.91799927 11.65499973 Tm [(10min)] TJ ET EMC /P <</Lang (zh-CN) /MCID 245 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 105.16799927 11.65499973 Tm [<0057>] TJ ET EMC /P <</MCID 246 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 115.66799927 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 483.6000061 cm /P <</MCID 247 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 1 Tr 0.30000001 w /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 499.20001221 cm /P <</Lang (zh-CN) /MCID 248 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr 0 g 0.30000001 w 0 G [<00D1>-4<00D2>-4<0072>-4<00D3>] TJ ET EMC /P <</MCID 249 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 42.16799927 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 47.41799927 11.65499973 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 514.79998779 cm /P <</MCID 251 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 0 g [(1.)] TJ ET EMC /P <</Lang (zh-CN) /MCID 252 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 10.5 11.65499973 Tm [<00D400D5006200630017009C>] TJ ET EMC /P <</MCID 253 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 73.5 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 530.40002441 cm /P <</MCID 254 >> BDC BT /FAAACE 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 90 348.89398193 cm /P <</MCID 255 >> BDC q 1 0 0 1 0 3.30000305 cm q 275.25 0 0 -87 0 87 cm /X3 Do Q Q EMC Q 1 0 0 -1 0 841.90002441 cm 
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