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23.67700005 Tm 2 Tr [<0009>-4<000A>-4<000B>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 407.58200073 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 31.20000076 cm /P <</MCID 7 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 207.6499939 11.56599998 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 102.23000336 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<000C>-4<000D>-4<000E>-4<000F>-4<0010>-4<0011>-3<0012>-4<0013>-4<0014>-4<0015>-4<0016>-4<0017>-4<0018>-4<0019>-4<0016>-4<001A>-3<001B>-4<001C>-4<001D>-4<001E>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 313.07000732 11.65499973 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 62.40000153 cm /P <</MCID 10 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.56599998 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 78 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<000D>-4<000E>-4<001F>-4<0020>-4<0021>] TJ ET EMC 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360.86401367 11.65499973 Tm [<0038>] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT 1 0 0 -1 368.05099487 11.65499973 Tm [<003C003D0011002D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT 1 0 0 -1 410.05099487 11.65499973 Tm [<0038>] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [<003E>-43<003F>-42<0040>-43<002D>-43<0038>-42<0041>-43<0042>-43<0043>-42<0044>-43<002D>-43<0045>-42<0017>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 131.37600708 27.25500107 Tm [(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAACH 10.5 Tf 1 0 0 -1 137.07400513 27.25500107 Tm [(?] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 148.02200317 27.25500107 Tm [(HEPES)] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 183.18499756 27.25500107 Tm [<0003>-43<0004>-42<0005>-43<0006>-43<0007>-42<0046>-43<0047>-43<0016>-42<001A>-43<0033>-43<0034>-42<0035>-43<0036>-43<0037>-42<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 28 >> BDC BT 1 0 0 -1 347.40499878 27.25500107 Tm [<0048>-43<0046>-42<0047>-43<0049>-43<004A>-42<004B>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 42.85499954 Tm [(HEPES)] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 32.5019989 42.85499954 Tm [<0017>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 43.41400146 42.85499954 Tm [(HEPES)] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 78.54100037 42.85499954 Tm [<004C>-39<004D>-39<0031>-40<004E>-39<004F>-39<0050>-39<0051>-40<0052>-39<0003>-39<0004>-39<0053>-40<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT 1 0 0 -1 209.48500061 42.85499954 Tm [<0054>-39<002E>-39<0055>-40<0056>-39<0057>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 266.67001343 42.85499954 Tm [(pH)] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 282.54000854 42.85499954 Tm [<0058>-39<0059>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 306.98901367 42.85499954 Tm [(6.8)] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 320.52600098 42.85499954 Tm [<005A>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 331.43798828 42.85499954 Tm [(8.)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 339.31298828 42.85499954 Tm [(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 347.6000061 42.85499954 Tm [<005B>-39<005C>-39<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT 1 0 0 -1 380.33599854 42.85499954 Tm [<005D>-39<0048>-39<0059>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 58.45499802 Tm [(pH7.2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 28.23600006 58.45499802 Tm [<005A>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 41.01399994 58.45499802 Tm [(7.)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 48.88899994 58.45499802 Tm [(4)] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 59.04199982 58.45499802 Tm [<005E>-217<002E>-217<005F>-217<0060>-217<002B>-217<0003>-217<0004>-217<0054>-217<0061>-217<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT 1 0 0 -1 186.82200623 58.45499802 Tm [<0062>-217<0063>-217<0064>-217<004D>-217<0065>-217<004B>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 266.11499023 58.45499802 Tm [(10)] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 278.89300537 58.45499802 Tm [<005A>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 291.67098999 58.45499802 Tm [(50mmol)1(/L)] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 338.28201294 58.45499802 Tm [<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT 1 0 0 -1 351.05999756 58.45499802 Tm [<0066>-217<0067>-217<0007>-217<0068>-217<0069>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 74.05500031 Tm [(20mmol)1(/LHEPES)] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 79.04699707 74.05500031 Tm [<006A006B006C006D005F0060002B0003000400540061006E>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 205.04699707 74.05500031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 187.19999695 cm /P <</MCID 56 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.56599998 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 202.80000305 cm /P <</MCID 57 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(HEPES)] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 34.8409996 11.65499973 Tm [<0003>-12<0004>-12<0005>-12<0006>-12<0007>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 87.97100067 11.65499973 Tm [(\(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAACH 10.5 Tf 1 0 0 -1 96.84400177 11.65499973 Tm [(?] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 107.47000122 11.65499973 Tm [(HeBS\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 136.17900085 11.65499973 Tm [<004C>-12<004D>-12<0031>-12<006F>-12<0016>-12<002B>-12<0029>-12<002A>-12<0036>-12<0037>-12<0006>-12<0007>-12<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 63 >> BDC BT 1 0 0 -1 274.31698608 11.65499973 Tm [<0046>-12<0047>-12<0070>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 308.82000732 11.65499973 Tm [(HEPES)] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 341.03601074 11.65499973 Tm [<0038>-12<0071>-12<0072>-12<0073>-12<0038>-12<0033>-12<0034>] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [<0005>-2<0045>-2<0074>-3<0049>-2<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT 1 0 0 -1 52.61500168 27.25500107 Tm [<0048>-2<0075>-2<0076>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 86.80899811 27.25500107 Tm [(pH)] TJ ET EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 102.29000092 27.25500107 Tm [<0058>-2<004B>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 125.96099854 27.25500107 Tm [(7.05)] TJ ET EMC /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 144.35899353 27.25500107 Tm [<005A>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 154.88200378 27.25500107 Tm [(7.12)] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 173.27999878 27.25500107 Tm [<0017>-2<0077>-2<0078>-3<0079>-2<007A>-2<007B>-2<007C>-2<007D>-3<007E>-2<007F>-2<0080>-2<0033>-2<0034>-2<0035>-3<0036>-2<0037>-2<0055>-2<0081>-2<002B>-3<0024>-2<0082>-2<0046>-2<0047>] TJ ET EMC /P <</Lang (zh-CN) /MCID 74 >> BDC BT 1 0 0 -1 0 42.85499954 Tm [<002E008300840085>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 44.625 42.85499954 Tm [(DNA)] TJ ET EMC /P <</Lang (zh-CN) /MCID 76 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 69.9980011 42.85499954 Tm [<00690086>] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT 1 0 0 -1 90.9980011 42.85499954 Tm [<0038>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 96.2480011 42.85499954 Tm [(DNA)] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 121.6210022 42.85499954 Tm [<00590029002A008700880089002B008A008B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT 1 0 0 -1 216.1210022 42.85499954 Tm [<0038>] TJ ET EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT 1 0 0 -1 221.3710022 42.85499954 Tm [<008C008D008A008B>] TJ ET EMC /P <</Lang (zh-CN) /MCID 82 >> BDC BT 1 0 0 -1 260.7460022 42.85499954 Tm [<007E>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 268.6210022 42.85499954 Tm [(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAACH 10.5 Tf 1 0 0 -1 273.8710022 42.85499954 Tm [(?] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 284.3710022 42.85499954 Tm [(HeBS)] TJ ET EMC /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 312.08200073 42.85499954 Tm [<0047008E>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 335.70700073 42.85499954 Tm [(DNA)] TJ ET EMC /P <</Lang (zh-CN) /MCID 88 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 361.07998657 42.85499954 Tm [<006300640059>] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 395.20498657 42.85499954 Tm [(10)] TJ ET EMC /P <</Lang (zh-CN) /MCID 90 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 405.70498657 42.85499954 Tm [<005A>] TJ ET EMC /P <</MCID 91 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 58.45499802 Tm [(50)] TJ ET EMC /P <</Lang (zh-CN) /MCID 92 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 10.5 58.45499802 Tm [<008F>] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 21 58.45499802 Tm [(g)] TJ ET EMC /P <</Lang (zh-CN) /MCID 94 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 28.875 58.45499802 Tm [<004B00900017>] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 60.375 58.45499802 Tm [(Hela)] TJ ET EMC /P <</Lang (zh-CN) /MCID 96 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 80.19599915 58.45499802 Tm [<0038>] TJ ET EMC /P <</MCID 97 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 90.69599915 58.45499802 Tm [(BALB)] TJ ET EMC /P <</Lang (zh-CN) /MCID 98 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 121.3239975 58.45499802 Tm [<00450029002A0083008400910092>] TJ ET EMC /P <</MCID 99 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 197.44900513 58.45499802 Tm [(16h)] TJ ET EMC /P <</Lang (zh-CN) /MCID 100 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 213.19900513 58.45499802 Tm [<0017>] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 223.69900513 58.45499802 Tm [(CHO)] TJ ET EMC /P <</Lang (zh-CN) /MCID 102 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 245.86799622 58.45499802 Tm [<0038>] TJ ET EMC /P <</MCID 103 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 256.36801147 58.45499802 Tm [(DUK)-1(X)] TJ ET EMC /P <</Lang (zh-CN) /MCID 104 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 286.69900513 58.45499802 Tm [<0038>] TJ ET EMC /P <</MCID 105 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 297.19900513 58.45499802 Tm [(B)] TJ ET EMC /P <</Lang (zh-CN) /MCID 106 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 304.20199585 58.45499802 Tm [<009300450029002A006B00940095007800960097>] TJ ET EMC /P <</Lang (zh-CN) /MCID 107 >> BDC BT 1 0 0 -1 409.20199585 58.45499802 Tm [<0038>] TJ ET EMC /P <</MCID 108 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 74.05500031 Tm [(DMSO)] TJ ET EMC /P <</Lang (zh-CN) /MCID 109 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 32.9659996 74.05500031 Tm [<00980099009A008C008D007C007D0094009B009C0036003700550081006E>] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 190.46600342 74.05500031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 280.79998779 cm /P <</MCID 111 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.56599998 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 296.3999939 cm /P <</Lang (zh-CN) /MCID 112 >> BDC BT /FAAACD 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [<000F0016001A009D0013>] TJ ET EMC /P <</Lang (zh-CN) /MCID 113 >> BDC BT 1 0 0 -1 52.5 11.65499973 Tm [<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 114 >> BDC BT 1 0 0 -1 60.65000153 11.65499973 Tm [<001800540016001A001B001C001D001E009E009F002E000D000E000F0010009D001300150016>] TJ ET EMC /P <</Lang (zh-CN) /MCID 115 >> BDC BT 1 0 0 -1 260.1499939 11.65499973 Tm [<0017>] TJ ET EMC /P <</Lang (zh-CN) /MCID 116 >> BDC BT 1 0 0 -1 268.29998779 11.65499973 Tm [<001800190016001A00A000A100A200A3002B00A400A5004500A600A7>] TJ ET EMC /P <</Lang (zh-CN) /MCID 117 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [<004800A8001600A900170018004B00A600A700AA00A0009B0010000D000E00AB00AC00AD006E>] TJ ET EMC Q Q 1 0 0 -1 0 841.90002441 cm 
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