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BT /FAAABH 22 Tf 1 0 0 -1 278.20700073 54.8769989 Tm 2 Tr [<0005>-4<0006>-4<0007>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAABD 22 Tf 1 0 0 -1 344.4710083 54.8769989 Tm 0 Tr [(\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABH 22 Tf 1 0 0 -1 351.32501221 54.8769989 Tm 2 Tr [<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAABD 16 Tf 1 0 0 -1 417.58898926 54.8769989 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 69.80000305 62.40000153 cm /P <</MCID 11 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 0 11.38799953 Tm /GS2 gs 0 g [(       )-1( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 42 11.38799953 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 13 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 10.5 27.25500107 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<000B>-4<000C>-4<000D>-4<000E>-4<000F>-4<0010>-3<0011>-4<0012>-4<0013>-4<0014>-4<0015>-4<0016>-4<0017>-4<0018>-4<0015>-4<0019>-3<001A>-4<001B>-4<001C>-4<001D>] TJ ET EMC /P <</MCID 14 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 221.33999634 27.25500107 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 93.59999847 cm /P <</MCID 15 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 109.19999695 cm /P <</MCID 16 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 124.80000305 cm /P <</MCID 17 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 140.3999939 cm /P <</Lang (zh-CN) /MCID 18 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<000C>-4<000D>-4<001E>-4<001F>-4<0020>] TJ ET EMC /P <</MCID 19 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 52.70999908 11.65499973 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 156 cm /P <</MCID 20 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(HEPES)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 27.04500008 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 32.4109993 11.65499973 Tm [<0021>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 43.02700043 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 48.39300156 11.65499973 Tm [(4-\(2-Hydroxyethyl\)p)-1(ip)-1(e)1(razin)-1(e)1(-1-ethan)-1(e)1(su)-1(lfo)-1(ni)-1(c)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 248.13900757 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 250.6289978 11.65499973 Tm [(acid)] TJ ET EMC /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 268.14099121 11.65499973 Tm [<0016>-11<0022>-11<0023>-11<0024>-11<0025>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 321.2210083 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 326.58700562 11.65499973 Tm [(N-\(2-)] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 348.41598511 11.65499973 Tm [<0026>-11<0027>-11<0028>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 380.26400757 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 385.63000488 11.65499973 Tm [(\))] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 388.81399536 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 34 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 394.17999268 11.65499973 Tm [<0029>-11<002A>] TJ ET EMC /P <</MCID 35 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 415.4119873 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 0 27.25500107 Tm [(-N')1(-)-1(2)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 20.84600067 27.25500107 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 26.09600067 27.25500107 Tm [<002B002C0016002D002E002F0030>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 99.59600067 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 104.84600067 27.25500107 Tm [(C8H18N)1(2O4S)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 162.1499939 27.25500107 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 167.3999939 27.25500107 Tm [<0016002D002E00310030>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 219.8999939 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 225.1499939 27.25500107 Tm [(238.31)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 254.41000366 27.25500107 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 259.66000366 27.25500107 Tm [<0016>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 270.16000366 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 275.41000366 27.25500107 Tm [(CAS)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 291.90899658 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 294.2829895 27.25500107 Tm [(Number)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 329.36700439 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 331.74099731 27.25500107 Tm [(7365)1(-45-9)] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 375.42300415 27.25500107 Tm [<0016003200330034>] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT 1 0 0 -1 0 42.85499954 Tm [<0035>-8<0036>-8<0037>-9<0038>-8<0015>-8<0039>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 63.51599884 42.85499954 Tm [(HEPES)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 90.56099701 42.85499954 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 95.89700317 42.85499954 Tm [<003A>-8<003B>-8<003C>-9<003D>-8<003E>-8<002E>-8<003F>-8<0037>-9<0040>-8<0041>-8<0042>-8<0016>-8<0043>-8<0044>-9<0045>-8<0046>-8<0047>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 275.85900879 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 281.19500732 42.85499954 Tm [(pH)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 293.2539978 42.85499954 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 298.58999634 42.85499954 Tm [<0048>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 309.17599487 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 314.51199341 42.85499954 Tm [(6.8)] TJ ET EMC /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 327.89199829 42.85499954 Tm [<0049>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 338.47799683 42.85499954 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 343.81399536 42.85499954 Tm [(8.2)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 357.10800171 42.85499954 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 362.44400024 42.85499954 Tm [<004A>-8<004B>-8<0016>-9<004C>-8<004D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT 1 0 0 -1 0 58.45499802 Tm [<0048>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 11.96399975 58.45499802 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 18.6779995 58.45499802 Tm [(pH7.)-1(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 45.49499893 58.45499802 Tm [<0049>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 57.45899963 58.45499802 Tm [(7.4)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 70.75299835 58.45499802 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 77.46700287 58.45499802 Tm [<004E>-139<0044>-140<004F>-139<0050>-140<0051>-139<0040>-140<0041>-139<0043>-139<0052>-140<0016>-139<0053>-140<0054>-139<0055>-140<003B>-139<0056>-139<0030>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 268.89099121 58.45499802 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 275.60501099 58.45499802 Tm [(10)] TJ ET EMC /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 287.7130127 58.45499802 Tm [<0049>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 299.67700195 58.45499802 Tm [(50mm)1(o)-1(l/L)] TJ ET EMC /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 344.97601318 58.45499802 Tm [<0016>-139<0057>-140<0058>-139<0004>-140<0059>-139<0005>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 416.76000977 58.45499802 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 0 74.05500031 Tm [(20mm)1(o)-1(l/L)-1(HEPES)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 70.87999725 74.05500031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 76.20899963 74.05500031 Tm [<0021>-8<005A>-7<005B>-8<005C>-7<004F>-8<0050>-7<0051>-8<0040>-7<0041>-8<0043>-7<0052>-8<0039>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 203.15699768 74.05500031 Tm [(HEPES)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 230.20199585 74.05500031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 235.53100586 74.05500031 Tm [<005D>-8<005E>-7<003A>-8<0048>-7<005F>-8<0060>-7<002F>-8<0057>-7<0058>-8<0061>-7<0033>-8<0034>-7<0062>-8<0063>-7<0064>-8<0043>-7<0065>] TJ ET EMC /P <</Lang (zh-CN) /MCID 88 >> BDC BT 1 0 0 -1 0 89.65499878 Tm [<0066004F00670068>] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 42 89.65499878 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 47.25 89.65499878 Tm [(pH)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 59.30899811 89.65499878 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 92 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 64.55899811 89.65499878 Tm [<00690039>] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 85.55899811 89.65499878 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 249.6000061 cm /P <</MCID 94 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.20001221 cm /P <</MCID 95 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(HEPES)-1(-BSA)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 46.87099838 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 97 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 52.22100067 11.65499973 Tm [<0003>-10<0004>] TJ ET EMC /P <</MCID 98 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 73.42099762 11.65499973 Tm [(\()] TJ ET EMC /P <</Lang (zh-CN) /MCID 99 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 76.70500183 11.65499973 Tm [<0005>-10<0006>-9<0007>] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 108.50499725 11.65499973 Tm [(\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 101 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 111.78900146 11.65499973 Tm [<0016>-10<001E>-9<0025>-10<0030>] TJ ET EMC /P <</MCID 102 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 154.18899536 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 159.53900146 11.65499973 Tm [(HACM)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 186.73199463 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 105 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 192.08200073 11.65499973 Tm [<0003>-10<0004>-9<0016>-10<006A>-9<0019>-10<0033>-9<0034>-10<0057>-9<0058>-10<0004>-9<0051>-10<006B>-9<002D>-10<006C>-9<003B>-10<0039>-9<004D>-10<0022>] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 382.88198853 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 388.23199463 11.65499973 Tm [(HEPES)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 415.27700806 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 109 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 27.25500107 Tm [<0054>-15<0055>-14<0030>] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 31.95899963 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 37.36199951 27.25500107 Tm [(20m)1(mo)-1(l/L)] TJ ET EMC /P <</Lang (zh-CN) /MCID 112 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 81.34999847 27.25500107 Tm [<0016>] TJ ET EMC /P <</MCID 113 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 92.00299835 27.25500107 Tm [(BSA)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 108.61399841 27.25500107 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 115 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 114.01699829 27.25500107 Tm [<0054>-15<0055>-14<0030>] TJ ET EMC /P <</MCID 116 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 145.97599792 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 151.3789978 27.25500107 Tm [(0.025%)] TJ ET EMC /P <</Lang (zh-CN) /MCID 118 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 182.97599792 27.25500107 Tm [<0016>-15<0005>] TJ ET EMC /P <</MCID 119 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 204.28199768 27.25500107 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 209.68499756 27.25500107 Tm [(Ca2+)] TJ ET EMC /P <</Lang (zh-CN) /MCID 121 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 231.01699829 27.25500107 Tm [<006D>] TJ ET EMC /P <</MCID 122 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 241.66999817 27.25500107 Tm [(Mg2+)] TJ ET EMC /P <</Lang (zh-CN) /MCID 123 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 266.29400635 27.25500107 Tm [<006E>-15<006F>-14<004D>-15<0070>-14<0071>-15<003E>-14<002E>-15<0016>-15<0072>-14<0073>-15<0074>-14<0075>-15<0076>-14<0077>] TJ ET EMC /P <</Lang (zh-CN) /MCID 124 >> BDC BT 1 0 0 -1 0 42.85499954 Tm [<007800160079007A00150019007B007C00330034007D007E0057005800220051007F0080006D005700580039>] TJ ET EMC /P <</MCID 125 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 231 42.85499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 312 cm /P <</MCID 126 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.6000061 cm /P <</Lang (zh-CN) /MCID 127 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<000C>-4<000D>-4<007B>-4<006B>-4<0020>] TJ ET EMC /P <</MCID 128 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 52.70999908 11.65499973 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 343.20001221 cm /P <</MCID 129 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 358.79998779 cm q 0.25 0.5 m 154.30000305 0.5 l 154.30000305 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</Lang (zh-CN) /MCID 130 >> BDC BT /FAAABH 9 Tf 1 0 0 -1 53.8030014 15.00499916 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<000C>-4<000D>-4<0024>-4<0025>] TJ ET EMC /P <</MCID 131 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 89.9469986 14.77600098 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 154.55000305 0 cm 0.25 0.5 m 50.75 0.5 l 50.75 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</Lang (zh-CN) /MCID 132 >> BDC BT /FAAABH 9 Tf 1 0 0 -1 11.06400013 15.00499916 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0081>-4<0082>] TJ ET EMC /P <</MCID 133 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 29.13599968 14.77600098 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 205.55000305 0 cm 0.25 0.5 m 76.25 0.5 l 76.25 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</Lang (zh-CN) /MCID 134 >> BDC BT /FAAABH 9 Tf 1 0 0 -1 14.77799988 15.00499916 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0083>-4<0084>-4<0085>-4<0086>] TJ ET EMC /P <</MCID 135 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 50.92200089 14.77600098 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 282.04998779 0 cm 0.25 0.5 m 51.45000076 0.5 l 51.45000076 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</Lang (zh-CN) /MCID 136 >> BDC BT /FAAABH 9 Tf 1 0 0 -1 6.89599991 15.00500011 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 137 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 34.00400162 15.00500011 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 333.75 0 cm 0.25 0.5 m 50.75 0.5 l 50.75 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</Lang (zh-CN) /MCID 138 >> BDC BT /FAAABH 9 Tf 1 0 0 -1 6.546 15.00500011 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0044>-4<0045>-4<0087>] TJ ET EMC /P <</MCID 139 >> BDC BT /FAAABD 9 Tf 1 0 0 -1 33.65399933 15.00500011 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 23.89999962 cm q 0.25 0.5 m 154.30000305 0.5 l 154.30000305 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 140 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 2.5309999 14.77600098 Tm /GS2 gs 0 g [(HEPES)-1(-BSA)] TJ ET EMC /P <</Lang (zh-CN) /MCID 141 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 44.95600128 15.00499916 Tm [<00030004>] TJ ET EMC /P <</MCID 142 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 62.95600128 14.77600098 Tm [(\(HACM)] TJ ET EMC /P <</Lang (zh-CN) /MCID 143 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 91.2440033 15.00499916 Tm [<00030004>] TJ ET EMC /P <</MCID 144 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 109.2440033 14.77600098 Tm [(,)] TJ ET EMC /P <</Lang (zh-CN) /MCID 145 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 111.48999786 15.00499916 Tm [<000500060007>] TJ ET EMC /P <</MCID 146 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 138.49000549 14.77600098 Tm [(\))] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 141.21899414 14.77600098 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 154.55000305 0 cm 0.25 0.5 m 50.75 0.5 l 50.75 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 148 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 8.85000038 15.00499916 Tm /GS2 gs 0 g [(100ml)] TJ ET EMC /P <</MCID 149 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 31.35000038 14.77600098 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 205.55000305 0 cm 0.25 0.5 m 76.25 0.5 l 76.25 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 150 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 28.35000038 15.00499916 Tm /GS2 gs 0 g [(RT)] TJ ET EMC /P <</MCID 151 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 37.34999847 14.77600098 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 282.04998779 0 cm 0.25 0.5 m 51.45000076 0.5 l 51.45000076 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 152 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 12.54399967 15.00500011 Tm /GS2 gs 0 g [(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 153 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 19.3560009 15.00500011 Tm [<008E>] TJ ET EMC /P <</MCID 154 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 28.3560009 15.00500011 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 333.75 0 cm 0.25 0.5 m 50.75 0.5 l 50.75 23.89999962 l 0.25 23.89999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 155 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 12.19400024 15.00500011 Tm /GS2 gs 0 g [(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 156 >> BDC BT /FAAACB 9 Tf 1 0 0 -1 19.00600052 15.00500011 Tm [<008F>] TJ ET EMC /P <</MCID 157 >> BDC BT /FAAAAI 9 Tf 1 0 0 -1 28.00600052 15.00500011 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.5 w 0 0.5 m 0 47.79999924 l S Q q 0.5 w 154.55000305 0.5 m 154.55000305 23.89999962 l S Q q 0.5 w 154.55000305 24.39999962 m 154.55000305 47.79999924 l S Q q 0.5 w 205.55000305 0.5 m 205.55000305 23.89999962 l S Q q 0.5 w 205.55000305 24.39999962 m 205.55000305 47.79999924 l S Q q 0.5 w 282.04998779 0.5 m 282.04998779 23.89999962 l S Q q 0.5 w 282.04998779 24.39999962 m 282.04998779 47.79999924 l S Q q 0.5 w 333.75 0.5 m 333.75 23.89999962 l S Q q 0.5 w 333.75 24.39999962 m 333.75 47.79999924 l S Q q 0.5 w 384.75 0.5 m 384.75 47.79999924 l S Q q 0.5 w -0.25 0.25 m 385 0.25 l S Q q 0.5 w 0.25 24.14999962 m 384.5 24.14999962 l S Q q 0.5 w -0.25 48.04999924 m 385 48.04999924 l S Q Q q 1 0 0 1 0 407.1000061 cm /P <</MCID 158 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 21 11.38799953 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 42 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 422.70001221 cm /P <</MCID 161 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 438.29998779 cm /P <</Lang (zh-CN) /MCID 162 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<0090>-4<0038>-4<0091>-4<0092>] TJ ET EMC /P <</MCID 163 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 42.16799927 11.65499973 Tm 0 Tr [(\()] TJ ET EMC /P <</Lang (zh-CN) /MCID 164 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 45.43899918 11.65499973 Tm 2 Tr [<000E>-4<000F>-4<0093>-4<0094>] TJ ET EMC /P <</MCID 165 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 87.60700226 11.65499973 Tm 0 Tr [(\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 166 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 90.87799835 11.65499973 Tm 2 Tr [<0020>] TJ ET EMC /P <</MCID 167 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 101.41999817 11.65499973 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 453.8999939 cm /P <</MCID 168 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 169 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 5.32200003 11.65499973 Tm [<006D00950096007B007C0097009800990039>] TJ ET EMC /P <</MCID 170 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 99.8219986 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 469.5 cm /P <</MCID 171 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 172 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 5.32200003 11.65499973 Tm [<006D009A009B00330034009C007300740016009D0096007400040016>] TJ ET EMC /P <</MCID 173 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 152.32200623 11.65499973 Tm [(4)] TJ ET EMC /P <</Lang (zh-CN) /MCID 174 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 157.64399719 11.65499973 Tm [<009E>] TJ ET EMC /P <</MCID 175 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 168.14399719 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 173.39399719 11.65499973 Tm [(400g)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 194.30200195 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 178 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 199.55200195 11.65499973 Tm [<003E009F>] TJ ET EMC /P <</MCID 179 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 220.55200195 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 225.80200195 11.65499973 Tm [(10min)] TJ ET EMC /P <</Lang (zh-CN) /MCID 181 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 252.75999451 11.65499973 Tm [<001600A000A100A2007F0039>] TJ ET EMC /P <</MCID 182 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 315.76000977 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 485.1000061 cm /P <</MCID 183 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(3)] TJ ET EMC /P <</Lang (zh-CN) /MCID 184 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 5.32200003 11.65499973 Tm [<006D0015>] TJ ET EMC /P <</MCID 185 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 26.3220005 11.65499973 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 31.5720005 11.65499973 Tm [(HEPES)-1(-BSA)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 78.44300079 11.65499973 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 188 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 83.69300079 11.65499973 Tm [<0003000400A300A400A500A6003300340016>] TJ ET EMC /P <</MCID 189 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 178.19299316 11.65499973 Tm [(4)] TJ ET EMC /P <</Lang (zh-CN) /MCID 190 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 183.51499939 11.65499973 Tm [<009E00830084003900A700A800A900AA00AB00AC00AD00AE00AF0039>] TJ ET EMC /P <</MCID 191 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 330.51501465 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 500.70001221 cm /P <</MCID 192 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 516.29998779 cm /P <</Lang (zh-CN) /MCID 193 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<00B0>-4<00B1>-4<00B2>-4<00B3>-4<0020>] TJ ET EMC /P <</MCID 194 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 52.70999908 11.65499973 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 531.90002441 cm /P <</MCID 195 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 196 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 5.32200003 11.65499973 Tm [<006D00B000B10035007600900038001600B4003100B500B600B700B80039>] TJ ET EMC /P <</MCID 197 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 162.82200623 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 547.5 cm /P <</MCID 198 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.65499973 Tm /GS2 gs 0 g [(2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 199 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 5.32200003 11.65499973 Tm [<006D003000B900BA005100BB00BC00BD00BE00BF001600C000C100AE00AF00C2009700C3003B00C4003700C500C6009000380039>] TJ ET EMC /P <</MCID 200 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 278.32199097 11.65499973 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 563.09997559 cm /P <</MCID 201 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 578.70001221 cm /P <</Lang (zh-CN) /MCID 202 >> BDC BT /FAAABH 10.5 Tf 1 0 0 -1 0 11.65499973 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<00C7>-4<00C8>-4<000C>-4<000D>-4<0020>] TJ ET EMC /P <</MCID 203 >> BDC BT /FAAABD 10.5 Tf 1 0 0 -1 52.70999908 11.65499973 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 594.29998779 cm /P <</MCID 204 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 0 11.38799953 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 609.90002441 cm q 0.25 0.5 m 380.75 0.5 l 380.75 16.14999962 l 0.25 16.14999962 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 205 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 11.67999935 Tm /GS2 gs 0 g [(Earle)] TJ ET EMC /P <</Lang (zh-CN) /MCID 206 >> BDC BT 1 0 0 -1 26.25 11.67999935 Tm [(?] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 36.75 11.67999935 Tm [(s)] TJ ET EMC /P <</Lang (zh-CN) /MCID 208 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 44.625 11.67999935 Tm [<00CF00D0007100D10042>] TJ ET EMC /P <</MCID 209 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 97.125 11.67999935 Tm [(\(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 210 >> BDC BT 1 0 0 -1 107.625 11.67999935 Tm [(?] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 118.125 11.67999935 Tm [(EBSS,)] TJ ET EMC /P <</Lang (zh-CN) /MCID 212 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 144.375 11.67999935 Tm [<00350006000700D700D800D9>] TJ ET EMC /P <</MCID 213 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 207.375 11.67999935 Tm [(\))] TJ ET EMC /P <</MCID 214 >> BDC BT /FAAAAI 10.5 Tf 1 0 0 -1 212.625 11.41299915 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 16.14999962 l S Q q 0.5 w 381 0.5 m 381 16.14999962 l S Q q 0.5 w -0.25 0.25 m 381.25 0.25 l S Q q 0.5 w -0.25 16.39999962 m 381.25 16.39999962 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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