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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 46.8429985 l -90 46.8429985 l h W n BT /FAAAAH 14 Tf 1 0 0 -1 0 44.0929985 Tm 1 0 0 rg [( )] TJ ET q 0 G 0.75 w -1.45000005 46.4679985 m 402.75 46.4679985 l S Q Q EMC /Artifact <> BDC q 1 0 0 1 90 770.32800293 cm -90 0 m 505.29998779 0 l 505.29998779 21.97200012 l -90 21.97200012 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 8.56900024 Tm 1 0 0 rg [( )-1( )-1( )] TJ /GS1 gs 0 g [-7944( )] TJ ET q 1 0 0 1 0 10.98600006 cm Q Q EMC q 1 0 0 1 90 42.54999924 cm /Artifact <> BDC q 1 0 0 1 14 -0.0000015 cm q 237.54554749 0 0 -44.09265137 0 44.09265137 cm /X1 Do Q Q EMC Q q 1 0 0 1 90 89.39299774 cm /P <> BDC BT /FAAABC 18 Tf 1 0 0 -1 207.6499939 22.05500031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABF 18 Tf 1 0 0 -1 44.61800003 53.40999985 Tm 2 Tr /GS2 gs 0 g 0.51428574 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0005>-4<0007>-3<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAACB 18 Tf 1 0 0 -1 207.26600647 53.40999985 Tm 0 Tr [(PPDK\))] TJ ET EMC /P <> BDC BT /FAAABF 18 Tf 1 0 0 -1 262.25 53.40999985 Tm 2 Tr [<000B>-4<000C>-4<000D>-4<000E>-4<000F>-4<0010>] TJ ET EMC /P <> BDC BT /FAAABC 18 Tf 1 0 0 -1 370.68200684 53.40999985 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 62.40000153 cm /P <> BDC BT /FAAABC 14 Tf 1 0 0 -1 0 20.73999977 Tm /GS2 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACD 14 Tf 1 0 0 -1 273 20.73999977 Tm 1 0 0 rg [<00110012001200130014>] TJ ET EMC /P <> BDC BT /FAAABC 14 Tf 1 0 0 -1 343 20.73999977 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 350 20.73999977 Tm [(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 357 20.73999977 Tm [(0)] TJ ET EMC /P <> BDC BT /FAAACD 14 Tf 1 0 0 -1 367.5 20.73999977 Tm [<0015>] TJ ET EMC /P <> BDC BT /FAAABC 14 Tf 1 0 0 -1 381.5 20.73999977 Tm [(/)] TJ ET EMC /P <> BDC BT 1 0 0 -1 385.39001465 20.73999977 Tm [(48)] TJ ET EMC /P <> BDC BT /FAAACD 14 Tf 1 0 0 -1 402.89001465 20.73999977 Tm [<0016>] TJ ET EMC /P <> BDC BT /FAAABC 14 Tf 1 0 0 -1 416.89001465 20.73999977 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 93.59999847 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 10.8760004 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 109.19999695 cm /P <> BDC BT /FAAADB 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0003>] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 9.03600025 11.10499954 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT /FAAADB 9 Tf 1 0 0 -1 22.5359993 11.10499954 Tm 2 Tr [<0004>] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 31.5720005 11.10499954 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT /FAAADB 9 Tf 1 0 0 -1 36.0719986 11.10499954 Tm 2 Tr [<0005>] TJ ET EMC /P <> BDC BT /FAAACD 9 Tf 1 0 0 -1 45.10800171 11.10499954 Tm 0 Tr [<001700180019001A001B001C001D001E>] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 119.35800171 11.10499954 Tm [(2-3)] TJ ET EMC /P <> BDC BT /FAAACD 9 Tf 1 0 0 -1 135.10800171 11.10499954 Tm [<002200230024002500260027002800290016002A002B00230019001A>] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 261.10800171 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 124.80000305 cm /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0019>-4<001A>-4<002C>-4<002D>-4<002E>] TJ ET EMC /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 45.18000031 11.10499954 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 140.3999939 cm /P <> BDC q /GS2 gs 1 g 230.26800537 1.96399999 m 255.0920105 1.96399999 l 255.0920105 13.63599968 l 230.26800537 13.63599968 l h f* Q q /GS2 gs 1 g 255.09199524 1.96399999 m 264.16598511 1.96399999 l 264.16598511 13.63599968 l 255.09199524 13.63599968 l h f* Q EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<0006>-8<0007>-8<0008>-9<0009>-8<0008>-8<000A>-8<000B>-9<000C>-8<000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 81.66600037 11.10499954 Tm [(pyruvate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.15299988 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.47699738 11.10499954 Tm [(phosphate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.96899414 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.29299927 11.10499954 Tm [(dikinase,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.53599548 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.86000061 11.10499954 Tm [(PPDK)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.11999512 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.44400024 11.10499954 Tm [(EC)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.94400024 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.26800537 11.10499954 Tm 0.2 g [(2.7.9.1)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 255.09199524 11.10499954 Tm [<000E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.16598511 11.10499954 Tm 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 275.48999023 11.10499954 Tm [(C4)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 288.31698608 11.10499954 Tm [<0010>-8<0011>-8<0012>-9<0013>-8<0014>-8<0015>-8<0008>-9<0016>-8<0017>-8<0010>-8<0011>-8<0018>-9<0019>-8<001A>] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 26.70499992 Tm [<000C>] TJ ET EMC /P <> BDC BT 1 0 0 -1 9 26.70499992 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.51300049 26.70499992 Tm [<001C001D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 36.76300049 26.70499992 Tm [(ATP)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 53.76499939 26.70499992 Tm [<001E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.27799988 26.70499992 Tm [<0006000700080012>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 99.52799988 26.70499992 Tm [(Pi)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 109.28399658 26.70499992 Tm [<001F00200021002200230024002500090008002600270028000600070008>] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.28399658 26.70499992 Tm [<0029>] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.79699707 26.70499992 Tm [<002A000C002B002C002D002E002F>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 317.04699707 26.70499992 Tm [(C4)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 329.79998779 26.70499992 Tm [<003000310018003200330034003500360037>] TJ ET EMC /P <> BDC BT 1 0 0 -1 410.79998779 26.70499992 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.30500031 Tm [<00380039003A003B003C003D003E003F002C00400041004200430029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 126 42.30500031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 187.19999695 cm /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 0 11.10499954 Tm 1 Tr 0.25714287 w /GS4 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 202.80000305 cm /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0019>-4<001A>-4<002F>-4<0030>-4<002E>] TJ ET EMC /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 45.18000031 11.10499954 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 218.3999939 cm /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [(P)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.00500011 11.10499954 Tm [(PDK)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 25.25900078 11.10499954 Tm [<00180044004500220023001C001D00090008002600270028000600070008>] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.25900269 11.10499954 Tm [<001E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 168.68099976 11.10499954 Tm [(AMP)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 190.43800354 11.10499954 Tm [<0012>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 201.68800354 11.10499954 Tm [(PPi)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 216.44900513 11.10499954 Tm [<00240025000600070008>] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.44900513 11.10499954 Tm [<001E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 269.8710022 11.10499954 Tm [(ATP)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 289.12298584 11.10499954 Tm [<0012>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 300.37298584 11.10499954 Tm [(Pi)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 307.8789978 11.10499954 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 316.30099487 11.10499954 Tm [<0046000800470048000C0049004A0021001C001D0006>] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 26.70499992 Tm [<00070008>] TJ ET EMC /P <> BDC BT 1 0 0 -1 18 26.70499992 Tm [<0012>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 29.25 26.70499992 Tm [(NAD)-1(H)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 57.4980011 26.70499992 Tm [<002400250046>] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.4980011 26.70499992 Tm [<00080012>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 104.7480011 26.70499992 Tm [(NAD)] TJ ET EMC /P <> BDC BT /FAAABC 6 Tf 1 0 0 -1 124.24700165 23.97800064 Tm [(+)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 127.6309967 26.70499992 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.6309967 26.70499992 Tm [<002E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 147.8809967 26.70499992 Tm [(340nm)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 175.1309967 26.70499992 Tm [<004B004C>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 195.3809967 26.70499992 Tm [(NAD)-1(H)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 223.6289978 26.70499992 Tm [<004D004E001A004F001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.6289978 26.70499992 Tm [<00500051>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 288.8789978 26.70499992 Tm [(P)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.88400269 26.70499992 Tm [(PDK)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 314.13800049 26.70499992 Tm [<005200530029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 341.13800049 26.70499992 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 249.6000061 cm /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 0 11.10499954 Tm 1 Tr 0.25714287 w /GS4 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 265.20001221 cm /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0031>-4<0032>-4<0033>-4<0029>-4<0034>-4<0035>-3<0036>-4<0037>-4<0038>-4<002E>] TJ ET EMC /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 90.36000061 11.10499954 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 280.79998779 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<0054005500560039003900570050001E005800280059005A005B001E005C00400028005D005E005F001E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 189 11.10499954 Tm [(1mL)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 208.2480011 11.10499954 Tm [<00600061006200630064001E00650066001E0067001200680069006A0029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 343.24798584 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 296.3999939 cm /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 0 11.10499954 Tm 1 Tr 0.25714287 w /GS4 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 312 cm /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<000B>-4<000C>-4<0029>-4<0039>-4<003A>-4<0036>-3<003B>-4<003C>-4<002E>] TJ ET EMC /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 81.3239975 11.10499954 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 327.6000061 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<006B006C005E0005>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 36 11.10499954 Tm [(6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.5 11.10499954 Tm [(0mL?)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 69.3239975 11.10499954 Tm [<006D001B>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 87.3239975 11.10499954 Tm [(4)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 91.8239975 11.10499954 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.8239975 11.10499954 Tm [<006F002D0070>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 127.8239975 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 343.20001221 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<00710072004A0005>] TJ ET EMC /P <> BDC BT 1 0 0 -1 36 11.10499954 Tm [<005E0034>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 56.25 11.10499954 Tm [(60)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.25 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.5 11.10499954 Tm [(mL?)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 91.8239975 11.10499954 Tm [<006D001B>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 109.8239975 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.3239975 11.10499954 Tm [(4)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 118.8239975 11.10499954 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.8239975 11.10499954 Tm [<006F002D0070>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 154.82400513 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 358.79998779 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<007100720073000500740072>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 54 11.10499954 Tm [(?] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.07600021 11.10499954 Tm [(2)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 65.8259964 11.10499954 Tm [<006D001B>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 83.8259964 11.10499954 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 95.82299805 11.10499954 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.82299805 11.10499954 Tm [<006F002D0070>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 131.82299805 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 374.3999939 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<007100720020>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 27 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 31.5 11.10499954 Tm [<0005>] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.5 11.10499954 Tm [<005E0034>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 60.75 11.10499954 Tm [(60)] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 69.75 11.10499954 Tm [<002D0029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 80.07299805 11.10499954 Tm [(?)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 91.89900208 11.10499954 Tm [<0075001B>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 109.89900208 11.10499954 Tm [(4)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 114.39900208 11.10499954 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.39900208 11.10499954 Tm [<006F002D0070003400760077004E001B00780079002E007A007B007C001B007D0043007E005C007F001A0059005A0080008100430029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 366.39898682 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 390 cm /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 0 11.10499954 Tm 1 Tr 0.25714287 w /GS4 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 405.6000061 cm /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0016>-4<002A>-4<0029>-4<001B>-4<003D>-4<0030>-3<002E>] TJ ET EMC /P <> BDC BT /FAAACB 9 Tf 1 0 0 -1 63.2519989 11.10499954 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.7519989 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 421.20001221 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<008200830084008500360086000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 63 11.10499954 Tm [(g)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 67.5 11.10499954 Tm [<000E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 72 11.10499954 Tm [<0005>] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.59600067 11.10499954 Tm [<006B006C005E00340076>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 125.59600067 11.10499954 Tm [(\(mL\))] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 144.08799744 11.10499954 Tm [<0087>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 155.33799744 11.10499954 Tm [(1)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 159.83799744 11.10499954 Tm [<0005>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 168.43400574 11.10499954 Tm [(5~10)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 189.05299377 11.10499954 Tm [<001800620088000D0089008A>] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.05299377 11.10499954 Tm [<008B006C008C>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 272.30300903 11.10499954 Tm [(0.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.05300903 11.10499954 Tm [(1g)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 290.30300903 11.10499954 Tm [<00840085001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 317.30300903 11.10499954 Tm [<008D008E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 337.55300903 11.10499954 Tm [(1mL)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 356.80099487 11.10499954 Tm [<006B006C005E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 383.80099487 11.10499954 Tm [<000E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 388.30099487 11.10499954 Tm [<001B0049008F>] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 26.70499992 Tm [<00670090009100920029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 45 26.70499992 Tm [(8000g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.5 26.70499992 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.75 26.70499992 Tm [(4)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 74.25 26.70499992 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.25 26.70499992 Tm [<0059005A>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 103.5 26.70499992 Tm [(10min)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 126.50099945 26.70499992 Tm [<001B006C007C0093001B00940067007C0095004B0029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 225.50100708 26.70499992 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 452.3999939 cm /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 0 11.10499954 Tm 1 Tr 0.25714287 w /GS4 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 468 cm /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 0 11.10499954 Tm 2 Tr /GS2 gs 0 g 0.25714287 w [<0019>-4<001A>-4<003E>-4<003F>-4<0036>-4<0040>-3<0016>-4<0041>-4<002E>] TJ ET EMC /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 81.3239975 11.10499954 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 483.6000061 cm /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [(1)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 4.5 11.10499954 Tm [<001E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 13.5 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 18 11.10499954 Tm /GS2 gs 0 g [<0056003900390057005000960097>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 83.25 11.10499954 Tm [(30min)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 108.50099945 11.10499954 Tm [<0098007C001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.50100708 11.10499954 Tm [<004000410099009A009B>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 182.75100708 11.10499954 Tm [(340nm)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 207.75100708 11.10499954 Tm [<001B00680069006A0040009C0029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 270.75100708 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 499.20001221 cm /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [(2)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 4.5 11.10499954 Tm [<001E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 13.5 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 18 11.10499954 Tm /GS2 gs 0 g [<009D009E004B004C>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 54 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 514.79998779 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 9 11.10499954 Tm [(1)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 13.5 11.10499954 Tm [<000E009F0042005E001800A000A10005>] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.5 11.10499954 Tm [<007D0043007E006C007100720073004A006D008D008E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 186.75 11.10499954 Tm [(25mL)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 210.4980011 11.10499954 Tm [<00710072004A0012>] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 248.7480011 11.10499954 Tm [<0021001D001E0003002D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 269.32299805 11.10499954 Tm [(L)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 277.0710144 11.10499954 Tm [<007100720020001B00A2005600A30091001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 358.0710144 11.10499954 Tm [<0094002F>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 378.3210144 11.10499954 Tm [(37)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 387.3210144 11.10499954 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 396.3210144 11.10499954 Tm [<006A0090>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 0 26.70499992 Tm [(5min)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 18.50099945 26.70499992 Tm [<0070004300A400A5001800710072005600A60080>] TJ ET EMC /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 108.50099945 26.70499992 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 120.3789978 26.70499992 Tm [<006E006F002D001B00A700A8002200A900AA00AB0029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 219.3789978 26.70499992 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 546 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 9 11.10499954 Tm [(2)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 13.5 11.10499954 Tm [<000E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.25 11.10499954 Tm [<002E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 31.5 11.10499954 Tm [(1mL)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 50.7480011 11.10499954 Tm [<00600061006200630064>] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.7480011 11.10499954 Tm [<0037008D008E>] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 124.9980011 11.10499954 Tm [<00030004002D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 138.82299805 11.10499954 Tm [(L)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 146.57099915 11.10499954 Tm [<009D009E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.57099915 11.10499954 Tm [<0012>] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 175.82099915 11.10499954 Tm [<002000030004002D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 194.14599609 11.10499954 Tm [(L)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 201.89399719 11.10499954 Tm [<009F0042005E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.89399719 11.10499954 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.47200012 11.10499954 Tm [<00A30091>] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.47200012 11.10499954 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.04998779 11.10499954 Tm [<00AC00AD00AE00AF>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 298.29998779 11.10499954 Tm [(340nm)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 325.54998779 11.10499954 Tm [<00B000B100B2>] TJ ET EMC /P <> BDC BT 1 0 0 -1 352.54998779 11.10499954 Tm [<00B3003900B4>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 381.79998779 11.10499954 Tm [(A1)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 395.04998779 11.10499954 Tm [<0012>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 406.29998779 11.10499954 Tm [(37)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 26.70499992 Tm [<006E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 9 26.70499992 Tm [<00220023>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 29.25 26.70499992 Tm [(5min)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 50.00099945 26.70499992 Tm [<0080001800B3003900B4>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 97.25099945 26.70499992 Tm [(A2)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 108.25099945 26.70499992 Tm [<001B>] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.25099945 26.70499992 Tm [<00500051>] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 137.50100708 26.70499992 Tm [<00320001003300010021002C0001>-1<001D>] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 179.86000061 26.70499992 Tm [<0029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 188.86000061 26.70499992 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 577.20001221 cm /P <> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.02700043 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 592.79998779 cm /P <> BDC BT /FAAACB 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [(P)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.49800014 11.10499954 Tm [(PDK)] TJ ET EMC /P <> BDC BT /FAAABF 9 Tf 1 0 0 -1 26.74600029 11.10499954 Tm 2 Tr 0.25714287 w [<0042>-4<0043>-4<0044>-4<0045>-4<002E>] TJ ET EMC /P <> BDC BT /FAAADH 9 Tf 1 0 0 -1 71.9260025 11.10499954 Tm 1 Tr /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 0 608.40002441 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 9 11.10499954 Tm [(1)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 13.5 11.10499954 Tm [<000E0082009D009E00B500B600B7005700500051>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 103.5 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 624 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<00B800B9004C00BA0005>] TJ ET EMC /P <> BDC BT 1 0 0 -1 45 11.10499954 Tm [<00BB>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 56.25 11.10499954 Tm [(mg)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 70 11.10499954 Tm [<0084008500B500B600BB005600BC00BD00BE>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 153.25 11.10499954 Tm [(1nmol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.25100708 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.50100708 11.10499954 Tm [(NAD)-1(H)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 206.74899292 11.10499954 Tm [<004C00BA0087004A00BF000C005200C000B800B90029>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 305.74899292 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 639.59997559 cm /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [(PPDK)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 23.01000023 11.10499954 Tm [<000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 32.00999832 11.10499954 Tm [(nmol/)1(min/mg)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.01300049 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.26300049 11.10499954 Tm [(prot)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 97.76100159 11.10499954 Tm [<000E00C1>] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 115.76100159 11.10499954 Tm [<00350032>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 124.54599762 11.10499954 Tm [(A×V)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 144.8710022 11.10499954 Tm [<002200C2>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 162.8710022 11.10499954 Tm [(?] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 167.80999756 11.10499954 Tm [<000D>] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 176.80999756 11.10499954 Tm [<0038002B0013>] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 190.16499329 11.10499954 Tm [<000E>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 199.16499329 11.10499954 Tm [(?0)] TJ ET EMC /P <> BDC BT /FAAABC 6 Tf 1 0 0 -1 213.24099731 8.37800026 Tm [(9)] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 216.24099731 11.10499954 Tm [(]÷\(V)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 235.92399597 11.10499954 Tm [<009D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 244.92399597 11.10499954 Tm [(×Cpr\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.49700928 11.10499954 Tm [( )] TJ ET EMC /P <> BDC BT /FAAAEF 9 Tf 1 0 0 -1 268.74700928 11.10499954 Tm [<003700220033002A00060027002B003200010037001C0008000A>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 333.56201172 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 655.20001221 cm /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 0 11.10499954 Tm /GS2 gs 0 g [<000D>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 9 11.10499954 Tm [(2)] TJ ET EMC /P <> BDC BT /FAAAEA 9 Tf 1 0 0 -1 13.5 11.10499954 Tm [<000E0082009D009E00C3003F00500051>] TJ ET EMC /P <> BDC BT /FAAABC 9 Tf 1 0 0 -1 85.5 11.10499954 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q 1 0 0 -1 0 841.90002441 cm
endstream
endobj
6 0 obj
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