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0 12.27200031 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.27200031 Tm [(CT)-1(TN)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 111.86000061 12.27200031 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 164.36000061 12.27200031 Tm [(   )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 180.11000061 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 79.23400116 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Anti-)-1(CTTN)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 106.34300232 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 108.71700287 12.27200031 Tm [(\(Ab-466\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 145.85699463 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 148.23100281 12.27200031 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 173.8809967 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 176.25500488 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 219.81399536 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 222.18800354 12.27200031 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 259.98400879 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 111.66799927 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<000B000D>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Am)1(p)-1(laxi)-1(n;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 105.70200348 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 108.0759964 12.27200031 Tm [(CT)-1(TN)1(;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 133.49499512 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 135.8690033 12.27200031 Tm [(EMS)-1(1;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 162.92900085 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 165.30299377 12.27200031 Tm [(SRC)-1(8)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 186.74899292 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 144.102005 cm /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 176.53599548 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0015000D>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.27200031 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.27200031 Tm [<0019001A>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.27200031 Tm [<001B001C>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 208.97000122 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<001E000D>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 90.69100189 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 241.40400696 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<001F000D>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(CT)-1(TN)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 85.61000061 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 273.8380127 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 93.99199677 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 96.36599731 12.27200031 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 125.72799683 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 306.27200317 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0024>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.27200031 Tm [<0025>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0026000D>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 117.48899841 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 126 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 338.70599365 cm /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 88.65000153 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 91.02400208 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 134.58299255 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 371.14001465 m 416.75 371.14001465 l 416.75 402.34002686 l -1.45000005 402.34002686 l h f* Q q 1 0 0 1 0 371.14001465 cm /P <</MCID 84 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 85 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 402.33999634 cm /P <</MCID 87 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.00500011 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 427.17401123 cm q /GS2 gs 1 g 0.375 0.75 m 143.92500305 0.75 l 143.92500305 187.94999695 l 0.375 187.94999695 l h f* Q q 0.375 0.75 m 143.92500305 0.75 l 143.92500305 187.94999695 l 0.375 187.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 97.52200317 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 97.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 144.67500305 0.75 m 422.42498779 0.75 l 422.42498779 187.94999695 l 144.67500305 187.94999695 l h f* Q q 1 0 0 1 144.30000305 0 cm 0.375 0.75 m 278.125 0.75 l 278.125 187.94999695 l 0.375 187.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Cort)1(actin)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 39.31299973 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 43.81299973 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 50.37400055 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 54.87400055 11.72200012 Tm [(overexpressed)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 117.01699829 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 121.51699829 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 129.45799255 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 133.95799255 11.72200012 Tm [(breast)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 160.74299622 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 165.24299622 11.72200012 Tm [(canc)-1(er)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 193.33299255 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 197.83299255 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 214.11000061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 218.61000061 11.72200012 Tm [(squa)1(mous)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 262.92001343 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 14.40999985 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 18.90999985 27.3220005 Tm [(carc)-1(inoma)1(s)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 67.58399963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 72.08399963 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 80.9260025 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 85.4260025 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 99.42700195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 103.92700195 27.3220005 Tm [(head)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 125.30599976 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 129.80599976 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 146.08299255 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 150.58299255 27.3220005 Tm [(ne)-1(ck.)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 172.81500244 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 177.31500244 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 193.12199402 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 197.62199402 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 235.1289978 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 239.6289978 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 270.93600464 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 6.56099987 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 11.06099987 42.92200089 Tm [(localized)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 48.74399948 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 53.24399948 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 61.18500137 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 65.68499756 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 79.68599701 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 84.18599701 42.92200089 Tm [(cy)-1(t)1(oplas)1(m)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 128.2539978 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 132.7539978 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 149.03100586 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 153.53100586 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 161.47200012 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 165.97200012 42.92200089 Tm [(areas)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 188.63000488 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 193.13000488 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 201.97200012 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 206.47200012 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 220.4730072 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 224.9730072 42.92200089 Tm [(ce)-1(ll-sub)1(str)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(at)1(u)-1(m)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 22.30699921 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 26.80699921 58.52199936 Tm [(contacts.)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 65.11399841 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 69.61399841 58.52199936 Tm [(This)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 86.87599945 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 91.37599945 58.52199936 Tm [(gene)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 112.89199829 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 117.39199829 58.52199936 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 132.07400513 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 136.57400513 58.52199936 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 152.75500488 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 157.25500488 58.52199936 Tm [(roles:)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 180.24699402 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 184.74699402 58.52199936 Tm [(\(1\))] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 196.03700256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 200.53700256 58.52199936 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 244.80299377 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 249.30299377 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 263.3039856 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 267.8039856 58.52199936 Tm [(i)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(nteractions)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 48.11100006 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 52.61100006 74.12200165 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 89.68299866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 94.18299866 74.12200165 Tm [(components)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 148.03799438 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 152.53799438 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 161.38000488 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 165.88000488 74.12200165 Tm [(ad)1(here)-1(ns-)1(type)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 228.3789978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 232.8789978 74.12200165 Tm [(jun)-1(ctio)1(n)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(s)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 4.16599989 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 8.66600037 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 24.94300079 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 29.44300079 89.72200012 Tm [(\(2\))] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 40.73300171 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 45.23300171 89.72200012 Tm [(org)1(anizing)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 91.18699646 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 95.68699646 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 109.68800354 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 114.18800354 89.72200012 Tm [(cy)-1(t)1(oske)-1(leton)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 168.83399963 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 173.33399963 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 189.61099243 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 194.11099243 89.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 208.52099609 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 213.02099609 89.72200012 Tm [(ad)1(hesion)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 252.22900391 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 256.72900391 89.72200012 Tm [(st)1(r)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(uc)-1(t)1(ure)-1(s)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 31.66699982 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 36.16699982 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 45.00899887 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 49.50899887 105.3219986 Tm [(epith)1(e)-1(lia)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 86.52400208 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 91.02400208 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 107.3010025 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 111.8010025 105.3219986 Tm [(carci)-1(noma)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 156.30900574 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 160.80900574 105.3219986 Tm [(ce)-1(lls.)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 181.55099487 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 186.05099487 105.3219986 Tm [(During)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 215.58700562 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 220.08700562 105.3219986 Tm [(ap)1(opt)1(osis,)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 264.24798584 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 14.0010004 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 18.50099945 120.92199707 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 56.00799942 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 60.50799942 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 91.81500244 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 96.31500244 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 102.87599945 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 107.37599945 120.92199707 Tm [(degra)1(ded)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 149.0269928 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 153.5269928 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 161.46800232 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 165.96800232 120.92199707 Tm [(a)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 170.94299316 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 175.44299316 120.92199707 Tm [(caspa)1(se)-1(-)1(depen)-1(d)1(e)-1(nt)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 260.01098633 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(manne)-1(r)1(.)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 35.20899963 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 39.70899963 136.52200317 Tm [(The)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 55.51599884 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 60.01599884 136.52200317 Tm [(ab)1(e)-1(rr)1(ant)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 96.59200287 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 101.09200287 136.52200317 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 145.32299805 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 149.82299805 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 158.66499329 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 163.16499329 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 178.6210022 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 183.1210022 136.52200317 Tm [(gene)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 204.63699341 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 209.13699341 136.52200317 Tm [(contribut)1(e)-1(s)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 258.02200317 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 262.52200317 136.52200317 Tm [(t)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(o)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 5.72200012 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 10.22200012 152.12199402 Tm [(tumor)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 36.7120018 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 41.2120018 152.12199402 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 55.62200165 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 60.12200165 152.12199402 Tm [(invasion)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 95.58999634 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 100.08999634 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 116.36699677 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 120.86699677 152.12199402 Tm [(metast)1(asis.)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 168.1210022 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 172.6210022 152.12199402 Tm [(Two)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 190.60800171 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 195.10800171 152.12199402 Tm [(splice)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 219.43200684 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 223.93200684 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 257.50201416 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 262.00201416 152.12199402 Tm [(th)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(at)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 8.32800007 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 12.82800007 167.72200012 Tm [(en)-1(cod)1(e)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 44.57799911 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 49.07799911 167.72200012 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 86.01799774 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 90.51799774 167.72200012 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 127.6780014 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 132.17799377 167.72200012 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 152.5249939 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 157.0249939 167.72200012 Tm [(been)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 178.53199768 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 183.03199768 167.72200012 Tm [(identified)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 223.96299744 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 228.46299744 167.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 240.74099731 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 245.24099731 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 260.69699097 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 265.19699097 167.72200012 Tm [(g)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 0 183.32200623 Tm [(en)-1(e.)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 17.92499924 183.32200623 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 187.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 144.30000305 0.75 m 144.30000305 187.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 187.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 188.32499695 m 423.17498779 188.32499695 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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