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BT 1 0 0 -1 185.56199646 54.8769989 Tm [<0004>-4<0008>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAABI 22 Tf 1 0 0 -1 229.73800659 54.8769989 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 78 cm /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT 1 0 0 -1 52.5 12.27200031 Tm [<00030004>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.27200031 Tm [(DUSP1/4\(Phosp)-1(ho)-1(-Ser)1(296/318\))] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 210.70199585 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 215.95199585 12.27200031 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 268.45199585 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 273.70199585 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 110.43399811 cm /P <</Lang (zh-CN) /MCID 13 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 14 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Anti-)-1(DU)1(S)-1(P1)1(/)-1(4)1(\()-1(P)1(h)-1(osph)-1(o-S)-1(e)1(r296/31)1(8\))] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 218.31100464 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 220.68499756 12.27200031 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 246.33500671 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 248.70899963 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 292.26800537 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 294.64199829 12.27200031 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 332.43798828 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 142.86799622 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 21 12.27200031 Tm [<000B000D>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(HVH1;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 90.17299652 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 92.54699707 12.27200031 Tm [(MKP)1(1;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 120.53500366 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 122.90899658 12.27200031 Tm [(CL)-1(1)1(00;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 151.69700623 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 154.07099915 12.27200031 Tm [(MKP)1(-1;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 185.27400208 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 187.647995 12.27200031 Tm [(PTPN)1(10/TY)-1(P)1(;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 243.55700684 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 245.93099976 12.27200031 Tm [(HVH2;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 273.10400391 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 275.47799683 12.27200031 Tm [(MKP)1(2;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 303.46600342 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 305.83999634 12.27200031 Tm [(MKP)1(-2)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 334.23300171 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 175.30200195 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 207.73599243 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 21 12.27200031 Tm [<0015000D>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.27200031 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 108.35800171 12.27200031 Tm [<0019001A>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 134.60800171 12.27200031 Tm [<001B001C>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 240.16999817 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 21 12.27200031 Tm [<001E000D>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 90.69100189 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 272.60400391 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 21 12.27200031 Tm [<001F000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(DUSP1/4\(Phosp)-1(ho)-1(-Ser)1(296/318\))] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 197.57699585 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 305.03799438 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 93.99199677 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 96.36599731 12.27200031 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 125.72799683 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 128.102005 12.27200031 Tm [(Rat)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 142.3500061 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 337.47198486 cm /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 117.48899841 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 126 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 369.90600586 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 117.48899841 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 402.33999634 m 416.75 402.33999634 l 416.75 433.54000854 l -1.45000005 433.54000854 l h f* Q q 1 0 0 1 0 402.33999634 cm /P <</MCID 88 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 89 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 433.54000854 cm /P <</MCID 91 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.00500011 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 458.37399292 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 47.54999924 l 0.375 47.54999924 l h f* Q q 0.375 0.75 m 163.7749939 0.75 l 163.7749939 47.54999924 l 0.375 47.54999924 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 92 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 27.3220005 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 47.54999924 l 164.5249939 47.54999924 l h f* Q q 1 0 0 1 164.1499939 0 cm 0.375 0.75 m 258.2250061 0.75 l 258.2250061 47.54999924 l 0.375 47.54999924 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Dual)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 19.77099991 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 24.27099991 11.72200012 Tm [(speci)-1(f)1(ic)-1(it)1(y)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 66.73999786 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 71.23999786 11.72200012 Tm [(ph)1(osph)1(ata)1(se)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 126.28199768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 130.78199768 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 148.0039978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 152.5039978 11.72200012 Tm [(deph)1(osph)1(orylates)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 229.75100708 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 234.25100708 11.72200012 Tm [(MA)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(P)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 5.50600004 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 10.00599957 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 37.09400177 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 41.59400177 27.3220005 Tm [(MAP)1(K1)-1(/ERK)1(2)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 98.8769989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 103.3769989 27.3220005 Tm [(on)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 114.64499664 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 119.14499664 27.3220005 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 139.50900269 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 144.00900269 27.3220005 Tm [('T)-1(h)1(r-18)-1(3')] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 182.48800659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 186.98800659 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 203.26499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 207.76499939 27.3220005 Tm [('T)-1(yr-)1(1)-1(85)-1(',)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 247.63200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 44.26599884 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 48.76599884 42.92200089 Tm [(its)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 58.68000031 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 63.18000031 42.92200089 Tm [(activit)1(y)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 93.65200043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 98.15200043 42.92200089 Tm [(during)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 126.58899689 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 131.08900452 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 145.08999634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 149.58999634 42.92200089 Tm [(mei)-1(o)1(tic)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 181.50700378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 186.00700378 42.92200089 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 200.41700745 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 204.91700745 42.92200089 Tm [(cy)-1(cle)-1(.)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 228.375 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 47.54999924 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 138 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 164.5249939 16.35000038 l h f* Q q 1 0 0 1 164.1499939 0 cm 0.375 0.75 m 258.2250061 0.75 l 258.2250061 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 139 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 63.90000153 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 141 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 146 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 164.5249939 16.35000038 l h f* Q q 1 0 0 1 164.1499939 0 cm 0.375 0.75 m 258.2250061 0.75 l 258.2250061 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 147 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(DU)1(SP1)-1(/4\(Phosp)1(ho-)1(Se)-1(r296)-1(/3)-1(18\))] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 135.77799988 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 80.25 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 31.95000076 l 0.375 31.95000076 l h f* Q q 0.375 0.75 m 163.7749939 0.75 l 163.7749939 31.95000076 l 0.375 31.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 149 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 150 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 31.95000076 l 164.5249939 31.95000076 l h f* Q q 1 0 0 1 164.1499939 0 cm 0.375 0.75 m 258.2250061 0.75 l 258.2250061 31.95000076 l 0.375 31.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 151 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Pept)1(i)-1(d)1(e)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 32.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 37.47200012 11.72200012 Tm [(seque)-1(nce)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 78.31900024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 82.81900024 11.72200012 Tm [(aro)1(u)-1(nd)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 113.80000305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 118.30000305 11.72200012 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 189.07400513 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 193.57400513 11.72200012 Tm [(site)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 208.59500122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 213.09500122 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 221.93699646 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 226.43699646 11.72200012 Tm [(serin)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 5.10599995 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 9.60599995 27.3220005 Tm [(29)-1(6/)-1(318)-1(\(I-)1(I-S\(p\)-)1(P-N\))] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 101.77300262 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 106.27300262 27.3220005 Tm [(derived)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 138.55499268 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 143.05499268 27.3220005 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 163.76600647 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 168.26600647 27.3220005 Tm [(Hu)-1(ma)1(n)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 199.72599792 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 204.22599792 27.3220005 Tm [(MKP-)1(1)-1(/2)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 242.53300476 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 247.03300476 27.3220005 Tm [(.)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 249.19999695 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 112.19999695 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 163.7749939 0.75 l 163.7749939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 178 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 181 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 164.5249939 16.35000038 l h f* Q q 1 0 0 1 164.1499939 0 cm 0.375 0.75 m 258.2250061 0.75 l 258.2250061 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 182 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(dual)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 18.67200089 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 23.17200089 11.72200012 Tm [(speci)-1(f)1(ic)-1(it)1(y)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 65.64099884 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 70.14099884 11.72200012 Tm [(ph)1(osph)1(ata)1(se)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 125.18299866 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 129.68299866 11.72200012 Tm [(1/)-1(4)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 144.08399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 128.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 163.7749939 0.75 l 163.7749939 31.95000076 l 0.375 31.95000076 l h f* Q q 0.375 0.75 m 163.7749939 0.75 l 163.7749939 31.95000076 l 0.375 31.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 190 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Synonyms)] TJ ET EMC /P <</Lang (zh-CN) /MCID 191 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 46.60800171 19.52199936 Tm [<0020>] TJ ET EMC /P <</MCID 192 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 55.60800171 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 164.5249939 0.75 m 422.375 0.75 l 422.375 31.95000076 l 164.5249939 31.95000076 l h f* Q q 1 0 0 1 164.1499939 0 cm 0.375 0.75 m 258.2250061 0.75 l 258.2250061 31.95000076 l 0.375 31.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 193 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(HV)-1(H1)-1(;)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 27.45299911 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 31.95299911 11.72200012 Tm [(MKP1;)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 59.40999985 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 63.90999985 11.72200012 Tm [(CL1)-1(00;)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 92.5490036 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 97.0490036 11.72200012 Tm [(MKP-)1(1)-1(;)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 128.3999939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 132.8999939 11.72200012 Tm [(PTPN10)-1(/TYP;)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 189.05299377 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 193.55299377 11.72200012 Tm [(HV)-1(H2)-1(;)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 221.0059967 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 225.5059967 11.72200012 Tm [(MKP2)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(;)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 2.16700006 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 6.66699982 27.3220005 Tm [(MKP-)1(2)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 35.85100174 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 160.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 0.75 m 164.1499939 47.54999924 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 48.29999924 m 164.1499939 63.90000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 64.65000153 m 164.1499939 80.25 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 81 m 164.1499939 112.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 112.94999695 m 164.1499939 128.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 164.1499939 129.30000305 m 164.1499939 160.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.75 0.75 m 422.75 160.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.125 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 47.92499924 m 422.375 47.92499924 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 64.27500153 m 422.375 64.27500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 80.625 m 422.375 80.625 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 112.57499695 m 422.375 112.57499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 128.92500305 m 422.375 128.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 160.875 m 423.125 160.875 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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