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46.79999924 cm /P <</Lang (zh-CN) /MCID 5 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(AU)1(RKB\(P)1(h)-1(osp)-1(ho-)-1(Thr232)1(\))] TJ ET EMC /P <</MCID 8 >> BDC BT 1 0 0 -1 182.80200195 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 188.05200195 12.82499981 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 240.55200195 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 245.80200195 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 12 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 13 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(A)1(URK)1(B\(Pho)-1(sph)-1(o-T)-1(hr2)1(32\))] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 190.41000366 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 192.78399658 12.82499981 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 218.43400574 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 220.80799866 12.82499981 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 264.36700439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 266.74099731 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 304.5369873 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000B000D>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AIK)1(2;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 85.30699921 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 87.68099976 12.82499981 Tm [(AIM1)1(;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 113.51100159 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 115.88500214 12.82499981 Tm [(ARK)1(2;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 141.2480011 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 143.62199402 12.82499981 Tm [(AurB;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 167.39599609 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 169.77000427 12.82499981 Tm [(IPL1;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 190.38499451 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 192.75900269 12.82499981 Tm [(ST)-1(K)1(5;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 216.28700256 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 218.66099548 12.82499981 Tm [(AIM-1;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 247.70500183 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 250.07899475 12.82499981 Tm [(ST)-1(K)1(12;)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 278.92800903 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 281.30200195 12.82499981 Tm [(PP)1(P1R4)1(8;)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 322.05099487 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 324.42498779 12.82499981 Tm [(aurkb-sv1;)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 369.11700439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 371.49099731 12.82499981 Tm [(aurkb-sv2)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 413.37298584 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0015000D>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019001A>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001D>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000D>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 90.69100189 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001F000D>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(AU)1(RKB\(P)1(h)-1(osp)-1(ho-)-1(Thr232)1(\))] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 169.67700195 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 76 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0020002100220023000D>] TJ ET EMC /P <</MCID 77 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 125.72799683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 128.102005 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 142.3500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002400250026000D>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 89 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006000700120027000D>] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 93 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 94 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 96 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 97 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 98 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 141.1499939 l 157.7749939 141.1499939 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 99 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(auror)1(a)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 198.36700439 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 202.86700439 11.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 229.95500183 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 234.45500183 11.72200012 Tm [(subf)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(amily)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 22.96100044 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 27.46100044 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 36.3030014 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 40.8030014 27.3220005 Tm [(serine)-1(/th)1(re)-1(o)1(n)-1(ine)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 112.15699768 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 116.65699768 27.3220005 Tm [(ki)-1(na)1(se)-1(s.)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 150.07699585 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 154.57699585 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 170.38400269 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 174.88400269 27.3220005 Tm [(gene)-1(s)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 200.56599426 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 205.06599426 27.3220005 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 245.40800476 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 249.90800476 27.3220005 Tm [(t)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(he)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 10.64799976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 15.14799976 42.92200089 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 38.30699921 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 42.80699921 42.92200089 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 58.98799896 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 63.48799896 42.92200089 Tm [(members)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 103.91799927 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 108.41799927 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 117.26000214 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 121.76000214 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 137.21600342 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 141.71600342 42.92200089 Tm [(subf)1(amily)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 183.25799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 187.75799561 42.92200089 Tm [(are)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 201.27600098 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 205.77600098 42.92200089 Tm [(located)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 237.59700012 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 242.09700012 42.92200089 Tm [(on)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 253.36500549 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(chromos)1(ome)-1(s)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 60.96099854 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 65.46099854 58.52199936 Tm [(19)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 76.01699829 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 80.51699829 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 96.79399872 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 101.29399872 58.52199936 Tm [(20)-1(.)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 114.01599884 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 118.51599884 58.52199936 Tm [(These)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 143.59599304 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 148.09599304 58.52199936 Tm [(ki)-1(na)1(se)-1(s)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 179.3500061 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 183.8500061 58.52199936 Tm [(pa)1(rticipat)1(e)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 229.8480072 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 234.3480072 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 242.28900146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 246.78900146 58.52199936 Tm [(th)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(e)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 5.10599995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 9.60599995 74.12200165 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 53.8370018 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 58.3370018 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 67.17900085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 71.67900085 74.12200165 Tm [(segregat)1(ion)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 122.9980011 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 127.4980011 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 136.33999634 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 140.83999634 74.12200165 Tm [(chromos)1(ome)-1(s)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 201.80099487 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 206.30099487 74.12200165 Tm [(during)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 234.73800659 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 239.23800659 74.12200165 Tm [(mit)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(osis)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 16.4489994 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 20.9489994 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 37.22600174 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 41.72600174 89.72200012 Tm [(mei)-1(o)1(sis)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 74.10900116 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 78.60900116 89.72200012 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 113.5059967 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 118.0059967 89.72200012 Tm [(asso)1(c)-1(iat)1(ion)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 165.93299866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 170.43299866 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 188.82899475 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 193.32899475 89.72200012 Tm [(mic)-1(r)1(otubules.)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 251.85499573 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(A)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 6.33300018 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 10.83300018 105.3219986 Tm [(pseudog)1(e)-1(ne)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 64.39399719 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 68.89399719 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 77.73600006 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 82.23600006 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 97.69200134 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 102.19200134 105.3219986 Tm [(gene)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 123.70800018 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 128.20799255 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 134.76899719 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 139.26899719 105.3219986 Tm [(located)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 171.08999634 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 175.58999634 105.3219986 Tm [(on)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 186.85800171 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 191.35800171 105.3219986 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 248.15299988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(8.)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 7.44399977 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 11.94400024 120.92199707 Tm [(Multiple)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 47.67599869 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 52.17599869 120.92199707 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 93.09799957 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 97.59799957 120.92199707 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 131.16799927 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 135.66799927 120.92199707 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 176.00999451 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 180.50999451 120.92199707 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 217.44999695 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 221.94999695 120.92199707 Tm [(isof)1(orm)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(s)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 4.16599989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 8.66600037 136.52200317 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 29.01300049 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 33.51300049 136.52200317 Tm [(been)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 55.02000046 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 59.52000046 136.52200317 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 85.20999908 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 89.70999908 136.52200317 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 101.98799896 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 106.48799896 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 121.94400024 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 126.44400024 136.52200317 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 150.12600708 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 244 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 245 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 157.7749939 16.35000038 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 246 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.0249939 -0.25 l 158.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 248 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 253 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.375 0.75 l 422.375 16.35000038 l 157.7749939 16.35000038 l h f* Q q 1 0 0 1 157.3999939 0 cm -0.625 -0.25 m 265.9750061 -0.25 l 265.9750061 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 254 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(AU)1(RKB\(Phos)1(pho-)1(Thr23)-1(2\))] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 108.11000061 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 0.75 m 157.3999939 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 141.8999939 m 157.3999939 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 158.25 m 157.3999939 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.75 0.75 m 422.75 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.125 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.375 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.375 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.2250061 m 423.125 174.2250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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