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12.27200031 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm [<00030004>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.27200031 Tm [(AU)1(RKA)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 119.29399872 12.27200031 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 171.79400635 12.27200031 Tm [(  )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 182.29400635 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 79.23400116 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Anti-)-1(A)1(URK)1(A)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 113.77700043 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 116.15100098 12.27200031 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 141.80099487 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 144.17500305 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 187.73399353 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 190.10800171 12.27200031 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 227.90400696 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 111.66799927 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<000B000D>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(AIK)1(;)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 79.98600006 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 82.36000061 12.27200031 Tm [(ARK)1(1;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 107.72299957 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 110.09700012 12.27200031 Tm [(AU)1(RA;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 137.49499512 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 139.8690033 12.27200031 Tm [(BTAK)1(;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 165.03700256 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 167.41099548 12.27200031 Tm [(ST)-1(K)1(6;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 190.93899536 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 193.31300354 12.27200031 Tm [(ST)-1(K)1(7;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 216.84100342 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 219.21499634 12.27200031 Tm [(ST)-1(K)1(15;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 248.06399536 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 250.43800354 12.27200031 Tm [(PP)1(P1R4)1(7)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 288.37701416 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 144.102005 cm /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 176.53599548 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0014>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0015000D>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<001600170018>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.27200031 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.27200031 Tm [<0019001A>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 208.97000122 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001B>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<001C000D>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 90.69100189 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 241.40400696 cm /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0004>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<001D000D>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(AU)1(RKA)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 93.04399872 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 273.8380127 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 93.99199677 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 306.27200317 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0022>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.27200031 Tm [<0023>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0024000D>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 117.48899841 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 126 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 338.70599365 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm /GS2 gs 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 88.65000153 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 91.02400208 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 134.58299255 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 371.14001465 m 416.75 371.14001465 l 416.75 402.34002686 l -1.45000005 402.34002686 l h f* Q q 1 0 0 1 0 371.14001465 cm /P <</MCID 86 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 402.33999634 cm /P <</MCID 89 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.00500011 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 427.17401123 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 172.3500061 l 0.375 172.3500061 l h f* Q q 0.375 0.75 m 157.0249939 0.75 l 157.0249939 172.3500061 l 0.375 172.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 91 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 157.7749939 172.3500061 l h f* Q q 1 0 0 1 157.3999939 0 cm 0.375 0.75 m 265.0249939 0.75 l 265.0249939 172.3500061 l 0.375 172.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 92 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 194.05099487 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 198.55099487 11.72200012 Tm [(cy)-1(cle)-1(-)1(re)-1(g)1(ul)-1(a)1(t)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ed)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 10.86299992 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 15.36299992 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 42.45100021 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 46.95100021 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 64.17299652 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 68.67299652 27.3220005 Tm [(ap)1(pears)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 102.82700348 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 107.32700348 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 116.40200043 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 120.90200043 27.3220005 Tm [(be)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 131.7559967 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 136.2559967 27.3220005 Tm [(involved)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 172.625 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 177.125 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 185.06599426 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 189.56599426 27.3220005 Tm [(mic)-1(r)1(otubule)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 241.75999451 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 246.25999451 27.3220005 Tm [(fo)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(rmat)1(ion)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 33.86000061 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 38.36000061 42.92200089 Tm [(and/or)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 67.64099884 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 72.14099884 42.92200089 Tm [(st)1(abilizat)1(ion)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 123.98300171 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 128.48300171 42.92200089 Tm [(at)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 136.81100464 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 141.31100464 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 155.31199646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 159.81199646 42.92200089 Tm [(spindle)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 190.92500305 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 195.42500305 42.92200089 Tm [(po)1(l)-1(e)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 214.39599609 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 218.89599609 42.92200089 Tm [(during)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 247.33299255 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 251.83299255 42.92200089 Tm [(c)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(hro)1(mosome)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 52.2820015 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 56.7820015 58.52199936 Tm [(segregat)1(ion.)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 110.26799774 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 114.76799774 58.52199936 Tm [(The)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 130.57499695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 135.07499695 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 172.58200073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 177.08200073 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 208.38900757 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 212.88900757 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 219.44999695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 223.94999695 58.52199936 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 249.63999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(at)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 8.32800007 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 12.82800007 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 26.82900047 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 31.32900047 74.12200165 Tm [(ce)-1(ntr)1(osome)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 82.43299866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 86.93299866 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 94.87400055 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 99.37400055 74.12200165 Tm [(interph)1(ase)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 144.7480011 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 149.2480011 74.12200165 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 167.82400513 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 172.32400513 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 188.60099792 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 193.10099792 74.12200165 Tm [(at)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 201.42900085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 205.92900085 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 219.92999268 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 224.42999268 74.12200165 Tm [(spindle)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 255.54299927 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(po)1(l)-1(es)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 23.13699913 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 27.63699913 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 35.57799911 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 40.07799911 89.72200012 Tm [(mito)1(sis.)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 72.87400055 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 77.37400055 89.72200012 Tm [(This)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 94.63600159 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 99.13600159 89.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 120.65200043 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 125.15200043 89.72200012 Tm [(may)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 143.32299805 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 147.82299805 89.72200012 Tm [(play)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 165.70399475 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 170.20399475 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 175.17900085 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 179.67900085 89.72200012 Tm [(role)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 196.33900452 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 200.83900452 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 208.77999878 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 213.27999878 89.72200012 Tm [(tumor)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 239.77000427 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 244.27000427 89.72200012 Tm [(de)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(velopment)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 46.13399887 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 50.63399887 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 66.91100311 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 71.41100311 105.3219986 Tm [(pro)1(gression.)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 124.77799988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 129.27799988 105.3219986 Tm [(A)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 135.61099243 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 140.11099243 105.3219986 Tm [(pro)1(c)-1(essed)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 183.83200073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 188.33200073 105.3219986 Tm [(pseudog)1(e)-1(ne)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 241.89300537 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 246.39300537 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 255.23500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 15.45600033 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 19.95599937 120.92199707 Tm [(gene)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 41.47200012 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 45.97200012 120.92199707 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 60.65399933 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 65.15399933 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 86.66100311 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 91.16100311 120.92199707 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 116.85099792 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 121.35099792 120.92199707 Tm [(on)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 132.6190033 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 137.1190033 120.92199707 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 193.91400146 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 198.41400146 120.92199707 Tm [(1,)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 205.85800171 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 210.35800171 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 226.63499451 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 231.13499451 120.92199707 Tm [(an)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 241.65600586 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 246.15600586 120.92199707 Tm [(un)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(pro)1(c)-1(essed)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 43.72100067 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 48.22100067 136.52200317 Tm [(pseudog)1(e)-1(ne)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 101.78199768 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 106.28199768 136.52200317 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 120.96399689 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 125.46399689 136.52200317 Tm [(been)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 146.97099304 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 151.47099304 136.52200317 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 177.16099548 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 181.66099548 136.52200317 Tm [(on)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 192.92900085 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 197.42900085 136.52200317 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 254.22399902 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(10)-1(.)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 12.72200012 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 17.22200012 152.12199402 Tm [(Multiple)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 52.95399857 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 57.45399857 152.12199402 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 98.37599945 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 102.87599945 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 136.44599915 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 140.94599915 152.12199402 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 181.28799438 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 185.78799438 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 199.78900146 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 204.28900146 152.12199402 Tm [(same)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 226.96899414 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 231.46899414 152.12199402 Tm [(pro)1(tei)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(n)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 5.546 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 10.04599953 167.72200012 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 30.39299965 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 34.89300156 167.72200012 Tm [(been)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 56.40000153 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 60.90000153 167.72200012 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 86.58999634 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 91.08999634 167.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 103.36799622 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 107.86799622 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 123.3239975 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 127.8239975 167.72200012 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 151.5059967 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 157.0249939 0.75 l 157.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 157.0249939 0.75 l 157.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 282 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 283 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 157.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 157.7749939 16.35000038 l h f* Q q 1 0 0 1 157.3999939 0 cm 0.375 0.75 m 265.0249939 0.75 l 265.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 284 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 46.03300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 188.70001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 0.75 m 157.3999939 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 157.3999939 173.1000061 m 157.3999939 188.70001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 188.70001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 189.07501221 m 423.17498779 189.07501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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