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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 697.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 101.5 l -90 101.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET Q EMC q 1 0 0 1 90 42.54999924 cm q 1 0 0 1 9 1 cm q 269.45001221 0 0 -90.09999847 0 90.09999847 cm /X1 Do Q Q Q q 1 0 0 1 90 144.05000305 cm q 1 0 0 1 88 0 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 49.67599869 23.67700005 Tm 0 Tr [(ATP6V1E2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 148.30000305 23.67700005 Tm 2 Tr [<0005>-4<0006>-4<0007>-4<0004>-4<0008>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 258.73999023 23.67700005 Tm 0 Tr [(   )] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 274.48999023 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 -88 43.20500183 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -88 60.30599976 Tm /GS2 gs 0 g [<0009000A000B000C000D>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -35.5 60.30599976 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 -25 60.30599976 Tm [<00030004>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 -1.375 60.30599976 Tm [(ATP6)1(V)-1(1E2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 44.91600037 60.30599976 Tm [<00050006000700040008>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.41600037 60.30599976 Tm [(   )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 113.16600037 60.30599976 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.46800232 cm /P <</Lang (zh-CN) /MCID 13 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<000E000A000B000C000D>] TJ ET EMC /P <</MCID 14 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Anti-)-1(A)1(T)-1(P)1(6V1E2)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 127.40000153 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 129.77400208 12.27200031 Tm [(rabbi)-1(t)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 155.42399597 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 157.79800415 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 201.35699463 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 203.73100281 12.27200031 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 241.5269928 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 112.90200043 cm /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<000F>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 25 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<000B000D>] TJ ET EMC /P <</MCID 26 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(VMA4;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 92.14199829 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 94.51599884 12.27200031 Tm [(ATP6)1(E)-1(1)1(;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 129.71299744 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 132.08700562 12.27200031 Tm [(ATP6)1(E)-1(L2;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 171.69799805 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 174.07200623 12.27200031 Tm [(ATP6)1(V)-1(1EL2)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 222.15299988 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 145.33599854 cm /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<001000110012000F000D>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<00130004>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 177.77000427 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<0004>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0014000D>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(ATP6)1(V)-1(1E2)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 106.66600037 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 210.20399475 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0016000D>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.27200031 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.27200031 Tm [<001A001B>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.63800049 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<001D000D>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Rabb)-1(it)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 90.69100189 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 105 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 275.07199097 cm /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<001E001F00200021000D>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 93.99199677 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 307.50601196 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<0022>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.27200031 Tm [<0023>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.27200031 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.27200031 Tm [<0024000D>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 117.48899841 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 126 12.27200031 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 339.94000244 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.27200031 Tm 0 g [<0006000700120025000D>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 63 12.27200031 Tm /GS2 gs 0 g [(rabbi)-1(t)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 88.65000153 12.27200031 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 91.02400208 12.27200031 Tm [(po)-1(lyclo)-1(nal)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 134.58299255 12.27200031 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 372.37399292 m 416.75 372.37399292 l 416.75 403.57400513 l -1.45000005 403.57400513 l h f* Q q 1 0 0 1 0 372.37399292 cm /P <</MCID 80 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 403.57400513 cm /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.00500011 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 428.4079895 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 78.75 l 0.375 78.75 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 78.75 l 0.375 78.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 84 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 42.92200089 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 78.75 l 148.7749939 78.75 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 78.75 l 0.375 78.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Subuni)-1(t)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 33.32799911 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 37.82799911 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 46.66999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 51.16999817 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 65.17099762 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 69.67099762 11.72200012 Tm [(periph)1(e)-1(ra)1(l)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 113.55899811 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 118.05899811 11.72200012 Tm [(V1)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 129.42300415 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 133.92300415 11.72200012 Tm [(complex)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 170.4019928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 174.9019928 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 183.7440033 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 188.2440033 11.72200012 Tm [(vacuolar)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 224.52999878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 229.02999878 11.72200012 Tm [(ATPa)1(se)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 260.2749939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(esse)-1(nt)1(ial)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 37.20800018 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 41.70800018 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 53.98600006 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 58.48600006 27.3220005 Tm [(assembly)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 98.23899841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 102.73899841 27.3220005 Tm [(or)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 111.89700317 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 116.39700317 27.3220005 Tm [(cata)1(l)-1(yt)1(i)-1(c)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 151.63200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 156.13200378 27.3220005 Tm [(func)-1(t)1(ion.)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 194.03900146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 198.53900146 27.3220005 Tm [(V-A)1(T)-1(Pa)1(se)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 239.76400757 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 244.26400757 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 250.82499695 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 255.32499695 27.3220005 Tm [(re)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(spo)1(n)-1(s)1(i)-1(b)1(le)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 40.99200058 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 45.49200058 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 57.77000046 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 62.27000046 42.92200089 Tm [(acidifying)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 103.88600159 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 108.38600159 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 113.36100006 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 117.86100006 42.92200089 Tm [(var)1(i)-1(ety)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 146.61399841 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 151.11399841 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 159.95599365 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 164.45599365 42.92200089 Tm [(intra)1(c)-1(ell)-1(ular)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 214.92300415 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 219.42300415 42.92200089 Tm [(compar)1(tm)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(en)-1(t)1(s)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 18.17099953 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 22.67099953 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 30.61199951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 35.11199951 58.52199936 Tm [(eu)-1(karyot)1(ic)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 79.8219986 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 84.3219986 58.52199936 Tm [(ce)-1(lls.)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 105.06400299 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 109.56400299 58.52199936 Tm [(This)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 126.8259964 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 131.32600403 58.52199936 Tm [(isof)1(orm)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 164.32000732 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 168.82000732 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 175.3809967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 179.8809967 58.52199936 Tm [(esse)-1(nt)1(ial)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 217.08900452 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 221.58900452 58.52199936 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 233.86700439 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 238.36700439 58.52199936 Tm [(en)-1(erg)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(y)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 4.76399994 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 9.26399994 74.12200165 Tm [(couplin)-1(g)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 46.88600159 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 51.38600159 74.12200165 Tm [(involved)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 87.75499725 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 92.25499725 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 100.19599915 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 104.69599915 74.12200165 Tm [(acidificatio)1(n)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 156.74899292 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 161.24899292 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 170.09100342 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 174.59100342 74.12200165 Tm [(acroso)1(me)-1(.)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 218.83099365 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 78.75 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 169 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 170 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 171 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ELISA,)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 25.90600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 30.40600014 11.72200012 Tm [(WB,)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 47.37799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 51.87799835 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 67.50499725 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 95.09999847 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 177 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 182 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 183 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ATP6V1)-1(E2)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 43.86600113 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 111.44999695 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 185 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 186 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 187 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Ful)-1(l)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 15.11699963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 19.61700058 11.72200012 Tm [(len)-1(g)1(th)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 47.31600189 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 51.81600189 11.72200012 Tm [(fusion)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 78.31099701 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 82.81099701 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 114.11799622 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 127.80000305 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 195 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 198 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 199 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ATPa)1(se)-1(,)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 33.41199875 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 37.91199875 11.72200012 Tm [(H+)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 51.54800034 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 56.04800034 11.72200012 Tm [(tr)1(anspor)1(ting,)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 111.64800262 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 116.14800262 11.72200012 Tm [(lysosoma)1(l)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 158.88499451 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 163.38499451 11.72200012 Tm [(31)-1(kDa,)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 192.83700562 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 197.33700562 11.72200012 Tm [(V1)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 208.70100403 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 213.20100403 11.72200012 Tm [(subunit)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 245.50100708 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 250.00100708 11.72200012 Tm [(E2)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 260.22698975 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 144.1499939 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 215 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Synonyms)] TJ ET EMC /P <</Lang (zh-CN) /MCID 216 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 46.60800171 11.72200012 Tm [<0020>] TJ ET EMC /P <</MCID 217 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 55.60800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 218 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(VMA4;)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 28.65699959 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 33.1570015 11.72200012 Tm [(ATP6E1;)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 67.82499695 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 72.32499695 11.72200012 Tm [(ATP6EL2)-1(;)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 111.61199951 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 116.11199951 11.72200012 Tm [(ATP6V1)-1(EL2)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 164.59700012 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 160.5 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 226 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Sw)1(iss)1(P)-1(r)1(o)-1(t:)] TJ ET EMC /P <</MCID 227 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.56900024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 228 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Q96)-1(A)1(0)-1(5)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 34.77799988 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 176.8500061 cm q 1 g 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q 0.375 0.75 m 148.0249939 0.75 l 148.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 230 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ELISA)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 25.2689991 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 29.7689991 11.72200012 Tm [(Recommend)1(e)-1(d)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 97.8010025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 102.3010025 11.72200012 Tm [(di)1(lution:)] TJ ET EMC /P <</MCID 235 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 140.14700317 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 148.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 148.7749939 16.35000038 l h f* Q q 1 0 0 1 148.3999939 0 cm 0.375 0.75 m 274.0249939 0.75 l 274.0249939 16.35000038 l 0.375 16.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 236 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(50)-1(00)-1(-)1(1)-1(00)-1(00)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 51.39400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 193.20001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 0.75 m 148.3999939 78.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 79.5 m 148.3999939 95.09999847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 95.84999847 m 148.3999939 111.44999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 112.19999695 m 148.3999939 127.79999542 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 128.54998779 m 148.3999939 144.1499939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 144.8999939 m 148.3999939 160.5 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 161.25 m 148.3999939 176.8500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 148.3999939 177.6000061 m 148.3999939 193.20001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 193.20001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 79.125 m 422.42498779 79.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 95.47499847 m 422.42498779 95.47499847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 111.82499695 m 422.42498779 111.82499695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 128.17498779 m 422.42498779 128.17498779 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 144.5249939 m 422.42498779 144.5249939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 160.875 m 422.42498779 160.875 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 177.2250061 m 422.42498779 177.2250061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 193.57501221 m 423.17498779 193.57501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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