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0 0 -1 108.94799805 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 111.3219986 12.82499981 Tm [(\(H+L)-1(\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 133.875 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E0009>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(IgG)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 77.21199799 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 26 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<00100009>] TJ ET EMC /P <</MCID 27 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001100120013>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00140015>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 180.95599365 m 416.75 180.95599365 l 416.75 212.1559906 l -1.45000005 212.1559906 l h f* Q q 1 0 0 1 0 180.95599365 cm /P <</MCID 34 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 240.09500122 cm q /GS2 gs 1 g 0.375 0.75 m 121.42500305 0.75 l 121.42500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 122.42500305 -0.25 l 122.42500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 38 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 122.17500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 122.17500305 156.75 l h f* Q q 1 0 0 1 121.80000305 0 cm -0.625 -0.25 m 301.625 -0.25 l 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153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 288.99899292 11.72200012 Tm [(i)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(n)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 5.546 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 10.04599953 27.3220005 Tm [(serum)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 36.73400116 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 41.23400116 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 59.63000107 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 64.12999725 27.3220005 Tm [(normal)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 94.63700104 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 99.13700104 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 123.02999878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 127.52999878 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 164.602005 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 169.102005 27.3220005 Tm [(8-17)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 188.82899475 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 193.32899475 27.3220005 Tm [(mg/mL)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 224.41600037 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 228.91600037 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 236.85699463 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 241.35699463 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 263.38198853 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 267.88198853 27.3220005 Tm [(bloo)1(d)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(.)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 2.16700006 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 6.66699982 42.92200089 Tm [(IgG)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 21.76199913 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 26.26199913 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 32.82300186 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 37.32300186 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 80.28399658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 84.78399658 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 97.06199646 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 101.56199646 42.92200089 Tm [(our)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 116.26599884 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 120.76599884 42.92200089 Tm [(defense)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 154.67399597 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 159.17399597 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 190.33999634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 194.83999634 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 263.93499756 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 268.43499756 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 284.71200562 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 289.21200562 42.92200089 Tm [(t)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(he)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 10.64799976 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 15.14799976 58.52199936 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 58.53099823 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 63.03099823 58.52199936 Tm [(are)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 76.5490036 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 81.0490036 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 122.63400269 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 127.13400269 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 137.64599609 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 142.14599609 58.52199936 Tm [(B)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 147.79299927 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 152.29299927 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 206.79800415 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 211.29800415 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 220.43899536 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 224.93899536 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 229.91400146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 234.41400146 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 251.92599487 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 256.42599487 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 265.26800537 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 269.76800537 58.52199936 Tm [(our)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 284.47198486 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 37.03300095 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 41.53300095 74.12200165 Tm [(immun)-1(e)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 76.99199677 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 81.49199677 74.12200165 Tm [(response.)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 122.65599823 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 127.15599823 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 142.96299744 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 147.46299744 74.12200165 Tm [(IgG)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 162.55799866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 167.05799866 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 206.2749939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 210.7749939 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 225.45700073 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 229.95700073 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 246.13800049 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 250.63800049 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 287.5039978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(func)-1(t)1(ions,)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 42.07300186 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 46.57300186 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 55.64799881 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 60.14799881 89.72200012 Tm [(bind)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 79.59400177 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 84.09400177 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 93.16899872 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 97.66899872 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 111.66999817 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 116.16999817 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 157.91799927 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 162.41799927 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 179.63999939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 184.13999939 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 215.16099548 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 219.66099548 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 233.66200256 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 238.16200256 89.72200012 Tm [(response)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 277.15899658 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 281.65899658 89.72200012 Tm [(an)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(d)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 5.75699997 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 10.25699997 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 19.33200073 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 23.83200073 105.3219986 Tm [(rec)-1(ruit)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 51.61899948 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 56.11899948 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 79.27799988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 83.77799988 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 102.35399628 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 106.85399628 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 123.1309967 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 127.6309967 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 171.01400757 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 175.51400757 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 184.58900452 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 189.08900452 105.3219986 Tm [(dest)1(roy)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 221.39300537 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 225.89300537 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 239.89399719 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 244.39399719 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 279.23800659 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 283.73800659 105.3219986 Tm [(T)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(he)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 10.64799976 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 15.14799976 120.92199707 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 56.70299911 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 61.20299911 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 70.04499817 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 74.54499817 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 88.54599762 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 93.04599762 120.92199707 Tm [(IgG)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 108.14099884 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 112.64099884 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 132.227005 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 136.727005 120.92199707 Tm [(is)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 143.28799438 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 147.78799438 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 191.93099976 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 196.43099976 120.92199707 Tm [(by)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 206.94299316 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 211.44299316 120.92199707 Tm [(soma)1(tic)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 245 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 249.5 120.92199707 Tm [(rec)-1(o)1(mbin)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(at)1(ion)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 21.98999977 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 26.48999977 136.52200317 Tm [(and)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 42.76699829 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 47.26699829 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 61.26800156 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 65.76799774 136.52200317 Tm [(number)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 99.58399963 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 104.08399963 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 112.9260025 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 117.4260025 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 166.79899597 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 171.29899597 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 179.24000549 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 183.74000549 136.52200317 Tm [(an)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 194.26100159 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 198.76100159 136.52200317 Tm [(individual)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 240.64500427 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 245.14500427 136.52200317 Tm [(at)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 253.4730072 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 257.97299194 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 262.94799805 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 267.44799805 136.52200317 Tm [(given)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 290.97601318 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(time)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 19.28800011 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 23.78800011 152.12199402 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 46.55199814 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 51.05199814 152.12199402 Tm [(is)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 57.61299896 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 62.11299896 152.12199402 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 104.75800323 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 109.25800323 152.12199402 Tm [(to)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 118.33300018 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 122.83300018 152.12199402 Tm [(be)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 133.68699646 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 138.18699646 152.12199402 Tm [(10)-1(11)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 159.29800415 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 163.79800415 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 199.53399658 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 121.42500305 0.75 l 121.42500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 122.42500305 -0.25 l 122.42500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 250 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <</MCID 251 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 122.17500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 122.17500305 31.95000076 l h f* Q q 1 0 0 1 121.80000305 0 cm -0.625 -0.25 m 301.625 -0.25 l 301.625 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 252 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Opt)1(imal)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 34.63299942 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 39.13299942 11.72200012 Tm [(test)1(e)-1(d)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 65.97499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 70.47499847 11.72200012 Tm [(ap)1(plic)-1(at)1(ions)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 122.40499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 126.90499878 11.72200012 Tm [(and)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 143.18200684 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 147.68200684 11.72200012 Tm [(wo)1(rk)-1(ing)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 182.54400635 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 187.04400635 11.72200012 Tm [(dilutions)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 224.31799316 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 228.81799316 11.72200012 Tm [(must)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 250.31599426 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 254.81599426 11.72200012 Tm [(be)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 265.67001343 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 270.17001343 11.72200012 Tm [(deter)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mine)-1(d)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 27.23699951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 31.73699951 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 42.24900055 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 46.74900055 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 60.75 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 65.25 27.3220005 Tm [(en)-1(d)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 81.65899658 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 86.15899658 27.3220005 Tm [(user.)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 106.58000183 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 188.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.80000305 0.75 m 121.80000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.80000305 157.5 m 121.80000305 188.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 188.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 189.07499695 m 423.17498779 189.07499695 l S Q Q q 1 0 0 1 0 429.54501343 cm /P <</MCID 279 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 457.48400879 cm /P <</MCID 280 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 485.42300415 cm /P <</MCID 281 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 513.36199951 cm /P <</MCID 282 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 541.30102539 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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