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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 112.43499756 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 272.55099487 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.86499023 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<0003000400050006000700080009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 139.125 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.33700562 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.71099854 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Bio)-1(tin)-1(-conj)-1(ugate)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.06900024 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.44299316 12.82499981 Tm [(Rabb)-1(it)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.13400269 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.50799561 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.72000122 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0016>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0017000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00180019001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001B001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001D001E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0006>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0007>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0004000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Bio)-1(tin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.10199738 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm /GS2 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.37400055 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm /GS2 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.75 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 273.63400269 cm q /GS2 gs 1 g 0.375 0.75 m 142.42500305 0.75 l 142.42500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 143.42500305 -0.25 l 143.42500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 143.17500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 143.17500305 172.3500061 l h f* Q q 1 0 0 1 142.80000305 0 cm -0.625 -0.25 m 280.625 -0.25 l 280.625 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ins)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.10700035 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.60700035 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.54800034 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.04800034 27.3220005 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.73600006 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.23600006 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.63200378 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.13200378 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.63899994 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.13899994 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.03199768 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.53199768 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.60400391 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.10400391 27.3220005 Tm [(9.5)-1(-)1(1)-1(2.5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.72000122 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.22000122 27.3220005 Tm [(mg/ml)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.08300781 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.58300781 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.52398682 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.02499962 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.52499962 42.92200089 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.03499985 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.53499985 42.92200089 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.62999725 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.12999725 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.69100189 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.19100189 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.1519928 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.6519928 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.92999268 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.42999268 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.13400269 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.63400269 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.54200745 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.04200745 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.20799255 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.70799255 42.92200089 Tm [(mic)-1(r)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(org)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.59600067 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.09600067 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.3730011 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.8730011 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.87400055 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.37400055 58.52199936 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.75700378 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.25700378 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.7749939 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.2749939 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.86000061 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.36000061 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.87199402 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.37199402 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.01899719 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.51899719 58.52199936 Tm [(lymphocyt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.27200031 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.77200031 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.91300011 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.41300011 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.38800049 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.88800049 74.12200165 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.40000153 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.90000153 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.74199677 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.24199677 74.12200165 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.94599915 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.44599915 74.12200165 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.47900391 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.97900391 74.12200165 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.43800354 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.93800354 74.12200165 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.102005 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.602005 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.40899658 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.90899658 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.0039978 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.5039978 74.12200165 Tm [(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(olec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.7840004 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.2840004 89.72200012 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.9659996 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.4659996 89.72200012 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.64700317 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.14700317 89.72200012 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.01300049 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.51300049 89.72200012 Tm [(func)-1(t)1(ions;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.58599854 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.08599854 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.16099548 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.66099548 89.72200012 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.10699463 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.60699463 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.68200684 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.18200684 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.18299866 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.68299866 89.72200012 Tm [(pa)1(tho)1(ge)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.546 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04599953 105.3219986 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.26799965 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.76799965 105.3219986 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.78900146 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.28900146 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.29000092 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.79000092 105.3219986 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.78700256 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.28700256 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.56399536 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.06399536 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.13900757 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.63900757 105.3219986 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.42599487 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.92599487 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.08500671 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.58500671 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.16099548 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.66099548 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.93798828 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.38299942 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.88299942 120.92199707 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.95800018 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.45800018 120.92199707 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.76200104 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.26200104 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.26300049 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.76300049 120.92199707 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.60699463 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.10699463 120.92199707 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.91400146 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.41400146 120.92199707 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.96899414 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.46899414 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.31100464 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.81100464 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.81199646 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.31199646 120.92199707 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.40701294 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.58600044 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.08600044 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.64699936 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.14699936 136.52200317 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.29000092 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.79000092 136.52200317 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.30200195 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.80200195 136.52200317 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.35899353 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.85899353 136.52200317 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.74899292 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.24899292 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.52600098 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.02600098 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.0269928 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.5269928 136.52200317 Tm [(numb)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(er)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.54300022 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.04300022 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.88500023 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.38500023 152.12199402 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.75800323 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.25800323 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.1989975 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.6989975 152.12199402 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.22000122 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.72000122 152.12199402 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.60400391 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.10400391 152.12199402 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.43200684 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.93200684 152.12199402 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.90699768 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.40699768 152.12199402 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.93499756 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.43499756 152.12199402 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.7230072 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.2230072 152.12199402 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.98699951 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.48699951 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.04800415 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.54800415 152.12199402 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(st)1(i)-1(ma)1(ted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.5379982 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.0379982 167.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.11299896 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.61299896 167.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.46700287 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.96700287 167.72200012 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.07800293 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.57800293 167.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.31399536 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 142.42500305 0.75 l 142.42500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 143.42500305 -0.25 l 143.42500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 143.17500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 143.17500305 31.95000076 l h f* Q q 1 0 0 1 142.80000305 0 cm -0.625 -0.25 m 280.625 -0.25 l 280.625 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.23899841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.73899841 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.01699829 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.51699829 11.72200012 Tm [(ELISA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.2559967 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.7559967 11.72200012 Tm [(1/)-1(10)-1(00-50)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.99499512 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.49499512 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.772995 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.272995 11.72200012 Tm [(West)1(e)-1(rn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.14599609 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.64599609 11.72200012 Tm [(blot)1(ting)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.91499329 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.41500854 11.72200012 Tm [(1/)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(20)-1(0-50)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.56100082 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.06100082 27.3220005 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.3390007 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.8390007 27.3220005 Tm [(Immunohist)1(oc)-1(h)1(e)-1(mist)1(ry/)-1(cytoce)-1(h)1(mistry)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.95500183 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.80000305 0.75 m 142.80000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 142.80000305 173.1000061 m 142.80000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q q 1 0 0 1 0 478.68399048 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 506.62298584 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 534.56201172 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 562.50097656 cm Q Q 1 0 0 -1 0 841.90002441 cm
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