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[( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.21099854 12.82499981 Tm [(\(H+L)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.76399994 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.13800049 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A0006000700080009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Goat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.70800018 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.08200073 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.29399872 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.66799927 12.82499981 Tm [(\(H+L)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.22100067 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E0009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.21199799 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<00100009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001100120013>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00140015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.85800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 180.95599365 m 416.75 180.95599365 l 416.75 212.1559906 l -1.45000005 212.1559906 l h f* Q q 1 0 0 1 0 180.95599365 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 240.09500122 cm q /GS2 gs 1 g 0.375 0.75 m 84.67500305 0.75 l 84.67500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 85.67500305 -0.25 l 85.67500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 85.42500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 85.42500305 141.1499939 l h f* Q q 1 0 0 1 85.05000305 0 cm -0.625 -0.25 m 338.375 -0.25 l 338.375 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.49899292 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.99899292 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.94000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.44000244 11.72200012 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 328.12799072 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.39599991 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.89599991 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.40299988 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.90299988 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.79599762 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.29599762 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.36799622 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.86799622 27.3220005 Tm [(8-17)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.59500122 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.09500122 27.3220005 Tm [(mg/mL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.18200684 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.68200684 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.6230011 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.1230011 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.147995 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.647995 27.3220005 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.15800476 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.6579895 27.3220005 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.75299072 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.25299072 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.81399536 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.31399536 27.3220005 Tm [(impor)1(tan)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 3.35299993 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.85300016 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.13100052 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.63100052 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.33499908 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.83499908 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.74299622 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.24299622 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.40899658 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.90899658 42.92200089 Tm [(mic)-1(r)1(oorg)1(anisms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.0039978 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.5039978 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.78100586 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.28100586 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.28199768 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.78199768 42.92200089 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.16500854 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.66500854 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.18301392 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.68301392 42.92200089 Tm [(pro)1(duc)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.86299992 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.36299992 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.875 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.375 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.02199936 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.52199936 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.02700043 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.52700043 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.66799927 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.16799927 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.14299774 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.64299774 58.52199936 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.15499878 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.65499878 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.49699402 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.99699402 58.52199936 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.70100403 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.20100403 58.52199936 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.23399353 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.73399353 58.52199936 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.19299316 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.69299316 58.52199936 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.85699463 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.35699463 58.52199936 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 320.16400146 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 324.66400146 58.52199936 Tm [(I)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(gG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.44999981 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.95000076 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.16699982 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.66699982 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.34899902 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.84899902 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.02999878 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.52999878 74.12200165 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.39599609 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.89599609 74.12200165 Tm [(func)-1(t)1(ions,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.96899414 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.46899414 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.54400635 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.04400635 74.12200165 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.49000549 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.99000549 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.06500244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.56500244 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.56599426 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.06600952 74.12200165 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 299.81399536 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.31399536 74.12200165 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 321.53601074 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.02099991 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.52099991 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.52199936 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.02199936 89.72200012 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.01899719 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.51899719 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.79599762 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.29599762 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.3710022 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.8710022 89.72200012 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.65800476 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.15800476 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.31700134 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.81700134 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.39300537 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.89300537 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.16999817 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.66999817 89.72200012 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.05300903 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.55300903 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.62799072 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.12799072 89.72200012 Tm [(dest)1(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 329.43200684 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.0010004 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.50099945 105.3219986 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.34500122 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.84500122 105.3219986 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.65200043 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.15200043 105.3219986 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.70700073 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.20700073 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.04899597 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.54899597 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.55000305 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.05000305 105.3219986 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.14500427 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.64500427 105.3219986 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.23100281 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.73100281 105.3219986 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.29200745 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.79200745 105.3219986 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.93499756 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.43499756 105.3219986 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.94699097 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.44699097 105.3219986 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.0039978 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.5039978 105.3219986 Tm [(rec)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(omb)1(i)-1(na)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.83399963 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.33399963 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.61100006 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.11100006 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.11199951 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.61199951 120.92199707 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.4280014 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.92799377 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.77000427 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.27000427 120.92199707 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.64300537 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.14300537 120.92199707 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.08399963 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.58399963 120.92199707 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.10499573 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.60499573 120.92199707 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.48901367 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.98901367 120.92199707 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.31698608 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.81698608 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.79199219 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.29199219 120.92199707 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 318.82000732 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 323.32000732 120.92199707 Tm [(ti)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.53999996 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.04000092 136.52200317 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.80400085 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.30400085 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.86500168 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.36500168 136.52200317 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.01000214 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.51000214 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.58499908 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.08499908 136.52200317 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.93900299 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.43899536 136.52200317 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.55000305 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.05000305 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.78599548 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 84.67500305 0.75 l 84.67500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 85.67500305 -0.25 l 85.67500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 85.42500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 85.42500305 31.95000076 l h f* Q q 1 0 0 1 85.05000305 0 cm -0.625 -0.25 m 338.375 -0.25 l 338.375 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Opt)1(imal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.63299942 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.13299942 11.72200012 Tm [(test)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.97499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.47499847 11.72200012 Tm [(ap)1(plic)-1(at)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.40499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.90499878 11.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.18200684 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.68200684 11.72200012 Tm [(wo)1(rk)-1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.54400635 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.04400635 11.72200012 Tm [(dilutions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.31799316 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.81799316 11.72200012 Tm [(must)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.31599426 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.81599426 11.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.67001343 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.17001343 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 320.16699219 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.51200008 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.01200008 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.01300049 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.51300049 27.3220005 Tm [(en)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.92200089 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.42200089 27.3220005 Tm [(user.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.84300232 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.09999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 85.05000305 0.75 m 85.05000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 85.05000305 141.8999939 m 85.05000305 173.09999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.09999084 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 173.47499084 m 423.17498779 173.47499084 l S Q Q q 1 0 0 1 0 413.94500732 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 441.88400269 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 469.82299805 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 497.76199341 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 525.70098877 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 553.64001465 cm Q Q 1 0 0 -1 0 841.90002441 cm
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