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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 152.28900146 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 179.8769989 23.67700005 Tm 0 Tr [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.19099426 23.67700005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.16499329 23.67700005 Tm [(\(H)1(+L\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.01098633 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00040005000600070008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<0003>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 76.125 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.33699799 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.71099854 12.82499981 Tm [(\(H+L)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.26399994 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.63800049 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<00090005000600070008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Bovin)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.14199829 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.51599884 12.82499981 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.72799683 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.10199738 12.82499981 Tm [(\(H+L)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.65499878 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D0008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.21199799 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000F0008>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001000110012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00130014>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00150016>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 180.95599365 m 416.75 180.95599365 l 416.75 212.1559906 l -1.45000005 212.1559906 l h f* Q q 1 0 0 1 0 180.95599365 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 240.09500122 cm q /GS2 gs 1 g 0.375 0.75 m 134.17500305 0.75 l 134.17500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 135.17500305 -0.25 l 135.17500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 54.72100067 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 134.92500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 134.92500305 172.3500061 l h f* Q q 1 0 0 1 134.55000305 0 cm -0.625 -0.25 m 288.875 -0.25 l 288.875 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunoglob)1(u)-1(lin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.82900238 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.32900238 11.72200012 Tm [(G)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.02200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.52200317 11.72200012 Tm [(\(IgG)1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.6289978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.1289978 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.69000244 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.19000244 11.72200012 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.56399536 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.06399536 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.90600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.40600586 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.40699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.90699768 11.72200012 Tm [(most)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.58099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.08099365 11.72200012 Tm [(ab)1(u)-1(nd)1(ant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.52600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.02600098 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.60700035 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.10700035 27.3220005 Tm [(serum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.79499817 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.29499817 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.69100189 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.19100189 27.3220005 Tm [(normal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.69799805 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.19799805 27.3220005 Tm [(leve)-1(ls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.09100342 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.59100342 27.3220005 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.66299438 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.16299438 27.3220005 Tm [(8-17)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.88999939 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.38999939 27.3220005 Tm [(mg/mL)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.477005 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.977005 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.91799927 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.41799927 27.3220005 Tm [(ad)1(u)-1(lt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.44299316 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(bloo)1(d.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.51000023 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.00999832 42.92200089 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.10499954 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.60499954 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.16600037 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.66600037 42.92200089 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.6269989 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.1269989 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.40499878 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.90499878 42.92200089 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.60899353 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.10899353 42.92200089 Tm [(defense)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.01699829 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.51699829 42.92200089 Tm [(ag)1(ainst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.68299866 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.18299866 42.92200089 Tm [(mic)-1(r)1(oorg)1(anis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ms)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.59899998 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.09900093 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.37599945 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.87599945 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.8769989 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.3769989 58.52199936 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.76000214 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.26000214 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.77799988 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.27799988 58.52199936 Tm [(pro)1(duc)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.86300659 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.36300659 58.52199936 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.875 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.375 58.52199936 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.02200317 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.52200317 58.52199936 Tm [(lymphocytes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.0269928 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.5269928 58.52199936 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.66799927 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.16799927 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.14300537 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(pa)1(rt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.51199913 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.01199913 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.85400009 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.35400009 74.12200165 Tm [(our)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.05799866 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.55799866 74.12200165 Tm [(ad)1(apt)1(ive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.59100342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.09100342 74.12200165 Tm [(immun)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.55000305 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.05000305 74.12200165 Tm [(response.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.21400452 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.71400452 74.12200165 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.52099609 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.02099609 74.12200165 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.11599731 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.61599731 74.12200165 Tm [(molec)-1(ule)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.83300781 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.33300781 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.01501465 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 89.72200012 Tm [(separa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.54700089 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.04700089 89.72200012 Tm [(func)-1(t)1(ions,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.12000275 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.62000275 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.69499969 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.19499969 89.72200012 Tm [(bind)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.64100647 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.14100647 89.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.21600342 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.71600342 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.71699524 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.21699524 89.72200012 Tm [(pa)1(tho)1(gen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.96499634 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.46499634 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.68699646 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.18699646 89.72200012 Tm [(eli)-1(cited)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.20800781 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.0010004 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.50099945 105.3219986 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.4980011 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.9980011 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.27500153 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.77500153 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.84999847 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.34999847 105.3219986 Tm [(rec)-1(ruit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.13700104 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.63699341 105.3219986 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.79600525 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.29600525 105.3219986 Tm [(ce)-1(lls)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.87199402 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.37199402 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.64900208 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.14900208 105.3219986 Tm [(molec)-1(ules)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.53199768 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.03199768 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.10699463 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.60699463 105.3219986 Tm [(dest)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(roy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.92199993 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.42200089 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.42300034 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.92300034 120.92199707 Tm [(antig)1(e)-1(n.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.76699829 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.26699829 120.92199707 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.0739975 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.5739975 120.92199707 Tm [(var)1(i)-1(a)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.1289978 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.6289978 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.47099304 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.97099304 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.97200012 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.47200012 120.92199707 Tm [(IgG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.56700134 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.06700134 120.92199707 Tm [(po)1(ol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.65299988 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.15299988 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.71400452 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.21400452 120.92199707 Tm [(gene)-1(r)1(ated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.35699463 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.51200008 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.01200008 136.52200317 Tm [(soma)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.56900024 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.06900024 136.52200317 Tm [(rec)-1(o)1(mbination)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.95899963 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.45899963 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.73599243 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.23599243 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.23699951 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.73699951 136.52200317 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.55299377 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.05299377 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.89500427 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.39500427 136.52200317 Tm [(speci)-1(f)1(ic)-1(it)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.76800537 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.26800537 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.20901489 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.52099991 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.02099991 152.12199402 Tm [(individual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.90499878 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.40499878 152.12199402 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.73300171 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.23300171 152.12199402 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.20800018 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.70800018 152.12199402 Tm [(given)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.23600006 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.73600006 152.12199402 Tm [(time)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.02400208 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.52400208 152.12199402 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.28799438 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.78799438 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.34899902 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.84899902 152.12199402 Tm [(estimat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.4940033 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.9940033 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.06900024 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.56900024 152.12199402 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.42300415 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.92300415 152.12199402 Tm [(10)-1(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.03399658 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.53399658 152.12199402 Tm [(v)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(aria)1(n)-1(t)1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.01199913 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q /GS2 gs 1 g 0.375 0.75 m 134.17500305 0.75 l 134.17500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 135.17500305 -0.25 l 135.17500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Applic)1(ations)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 56.50899887 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 134.92500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 134.92500305 31.95000076 l h f* Q q 1 0 0 1 134.55000305 0 cm -0.625 -0.25 m 288.875 -0.25 l 288.875 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Opt)1(imal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.63299942 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.13299942 11.72200012 Tm [(test)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.97499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.47499847 11.72200012 Tm [(ap)1(plic)-1(at)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.40499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.90499878 11.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.18200684 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.68200684 11.72200012 Tm [(wo)1(rk)-1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.54400635 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.04400635 11.72200012 Tm [(dilutions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.31799316 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.81799316 11.72200012 Tm [(must)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.31599426 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.81599426 11.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.67001343 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.17001343 11.72200012 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(etermine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.24000168 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.74000168 27.3220005 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.2519989 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.7519989 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.75299835 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.25299835 27.3220005 Tm [(en)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.66200256 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.16200256 27.3220005 Tm [(user.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.58300018 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 134.55000305 0.75 m 134.55000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 134.55000305 173.1000061 m 134.55000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q q 1 0 0 1 0 445.14498901 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 473.08401489 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 501.02301025 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 528.9619751 cm Q Q 1 0 0 -1 0 841.90002441 cm
endstream
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