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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 74.73899841 23.67700005 Tm 0 g [(XPNPEP2)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 163.85600281 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 340.55999756 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(XPN)1(PEP2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.9489975 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 107.1989975 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 191.19900513 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(XPN)1(PEP2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.9489975 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.32299805 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.5249939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.89900208 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.8789978 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.25300598 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.727005 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(X-p)-1(r)1(o)-1(lyl)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.9509964 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.32499695 12.82499981 Tm [(amin)-1(opepti)-1(dase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.26699829 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.64100647 12.82499981 Tm [(\(ami)-1(nop)-1(e)1(p)-1(tidas)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.76699829 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.14100647 12.82499981 Tm [(P\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.74899292 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.1230011 12.82499981 Tm [(2,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.06500244 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.43899536 12.82499981 Tm [(me)1(mb)-1(r)1(an)-1(e)1(-b)-1(oun)-1(d;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 346.01400757 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 348.38800049 12.82499981 Tm [(AP)1(P2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 373.44299316 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 375.81698608 12.82499981 Tm [(AEACEI)] TJ ET EMC /P <> BDC BT 1 0 0 -1 406.46600342 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACH 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 273.63400269 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(450-6)1(49)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(XPN)1(PEP2)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 349.19100952 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q /GS2 gs 1 g -1.45000005 302.57299805 m 416.75 302.57299805 l 416.75 333.77301025 l -1.45000005 333.77301025 l h f* Q q 1 0 0 1 0 302.57299805 cm /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 333.77301025 m 416.75 333.77301025 l 416.75 364.97302246 l -1.45000005 364.97302246 l h f* Q q 1 0 0 1 0 333.77301025 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACH 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 364.97299194 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 392.9119873 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 19.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 19.52199936 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 147.67500305 31.95000076 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(X-p)1(rolyl)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.1590004 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.6590004 11.72200012 Tm [(aminop)1(e)-1(pt)1(idas)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.08399963 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.58399963 11.72200012 Tm [(\(aminop)1(e)-1(pt)1(idas)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.01499939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.51499939 11.72200012 Tm [(P\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.0269928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.5269928 11.72200012 Tm [(2,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.97099304 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.47099304 11.72200012 Tm [(membrane-)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(bo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.31800079 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 31.95000076 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 147.67500305 16.35000038 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(AP)1(P2)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.79000092 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.29000092 11.72200012 Tm [(AE)1(ACEI)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.51800156 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 48.29999924 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 147.67500305 16.35000038 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(O43)-1(89)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 64.65000153 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 147.67500305 16.35000038 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC1)-1(26)-1(17)-1(4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 147.67500305 31.95000076 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(E)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.94799995 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 112.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 147.67500305 16.35000038 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 129.30000305 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 147.67500305 16.35000038 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 145.6499939 cm q /GS2 gs 1 g 0.375 0.75 m 146.92500305 0.75 l 146.92500305 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 147.92500305 -0.25 l 147.92500305 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 147.67500305 0.75 m 422.42498779 0.75 l 422.42498779 78.75 l 147.67500305 78.75 l h f* Q q 1 0 0 1 147.30000305 0 cm -0.625 -0.25 m 276.125 -0.25 l 276.125 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Aminop)1(e)-1(p)1(tida)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.78299713 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.28299713 11.72200012 Tm [(P)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.78900146 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.28900146 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.84999847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.34999847 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.32499695 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.82499695 11.72200012 Tm [(hydro)1(lase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.68699646 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.18699646 11.72200012 Tm [(speci)-1(f)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.14399719 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.64399719 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.92199707 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.42199707 11.72200012 Tm [(N-t)1(e)-1(r)1(mi)-1(na)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.27200317 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.77200317 11.72200012 Tm [(im)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ido)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.8739996 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.37400055 27.3220005 Tm [(bo)1(n)-1(d)1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.47900009 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.97900009 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.0759964 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.5759964 27.3220005 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.09400177 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.59400177 27.3220005 Tm [(common)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.96299744 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.46299744 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.53799438 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.03799438 27.3220005 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.94700623 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.44700623 27.3220005 Tm [(collagen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.85600281 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.35600281 27.3220005 Tm [(degra)1(da)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(tio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.01600075 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.51600075 42.92200089 Tm [(pro)1(duc)-1(t)1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.92399979 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.4240036 42.92200089 Tm [(ne)-1(uro)1(peptid)1(e)-1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.32699585 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.82699585 42.92200089 Tm [(vaso)1(active)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.47999573 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.97999573 42.92200089 Tm [(pept)1(ides,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.52600098 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.02600098 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.30299377 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.80299377 42.92200089 Tm [(cy)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(okine)-1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.00099945 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.50099945 58.52199936 Tm [(Structurally,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.5739975 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.0739975 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.07499695 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.57499695 58.52199936 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.95599365 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.45599365 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.01699829 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.51699829 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.49200439 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.99200439 58.52199936 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.2559967 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.7559967 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.5980072 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.0980072 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.09899902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.59899902 58.52199936 Tm [('pita)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.37701416 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(bread)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.02199936 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.52199936 74.12200165 Tm [(fo)1(l)-1(d)1(')] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.82300186 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.32300186 74.12200165 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.40499878 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.90499878 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.18199921 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.68199921 74.12200165 Tm [(occ)-1(urs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.57800293 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.07800293 74.12200165 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.01899719 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.51899719 74.12200165 Tm [(mammalia)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.07800293 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.57800293 74.12200165 Tm [(tiss)1(u)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.47599792 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.97599792 74.12200165 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.91700745 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.41700745 74.12200165 Tm [(bo)1(t)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.40000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 0.75 m 147.30000305 31.95000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 32.70000076 m 147.30000305 48.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 49.05000305 m 147.30000305 64.65000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 65.40000153 m 147.30000305 81 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 81.75 m 147.30000305 112.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 113.69999695 m 147.30000305 129.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 130.05000305 m 147.30000305 145.65000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 147.30000305 146.40000916 m 147.30000305 224.40000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 224.40000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 32.32500076 m 422.42498779 32.32500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 48.67500305 m 422.42498779 48.67500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.02500153 m 422.42498779 65.02500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 81.375 m 422.42498779 81.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 113.32499695 m 422.42498779 113.32499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 129.67500305 m 422.42498779 129.67500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 146.02500916 m 422.42498779 146.02500916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.77500916 m 423.17498779 224.77500916 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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