%PDF-1.5
%ÈÈÈÈÈÈ?1 0 obj
<</Author(\376\377|\211\202rN60\235)/Creator(Aspose Ltd.)/Producer(Aspose.PDF for .NET 19.2)/CreationDate(D:20200615072700Z)/ModDate(D:20200812231429+08'00')>>
endobj
2 0 obj
<</Type/Catalog/Pages 3 0 R/Lang(en-US)/StructTreeRoot 38 0 R/MarkInfo<</Marked true>>/Metadata 118 0 R>>
endobj
3 0 obj
<</Type/Pages/Count 2/Kids[4 0 R 35 0 R]>>
endobj
4 0 obj
<</Type/Page/Parent 3 0 R/Contents 5 0 R/MediaBox[0 0 595.29998779 841.90002441]/Resources<</Font<</FAAAAH 7 0 R/FAAABB 11 0 R/FAAABE 14 0 R/FAAABJ 19 0 R/FAAACF 25 0 R/FAAACJ 29 0 R/FAAADC 32 0 R>>/ExtGState<</GS1 18 0 R/GS2 23 0 R>>/XObject<</X1 9 0 R>>>>/Group<</Type/Group/S/Transparency/CS/DeviceRGB>>/StructParents 0/Tabs/S>>
endobj
5 0 obj
<</Length 32623>>stream
1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 92.26000214 23.67700005 Tm 0 g [(VRK3)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 146.33599854 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 323.04000854 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(VRK3)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 85.43599701 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 90.68599701 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 174.68600464 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(VRK3)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 85.43599701 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 87.80999756 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 121.01200104 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 123.38600159 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 183.36599731 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 185.74000549 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 220.21400452 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(vacc)1(i)-1(ni)-1(a)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 97.01699829 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 99.39099884 12.82499981 Tm [(re)1(l)-1(ate)1(d)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 129.9730072 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 132.34700012 12.82499981 Tm [(kinas)-1(e)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 159.40699768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 161.78100586 12.82499981 Tm [(3)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 167.10299683 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 44 >> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 273.63400269 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 48 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(213-4)1(12)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(VRK3)] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 335.03601074 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q /GS2 gs 1 g -1.45000005 302.57299805 m 416.75 302.57299805 l 416.75 333.77301025 l -1.45000005 333.77301025 l h f* Q q /GS2 gs 1 g -1.45000005 333.77301025 m 416.75 333.77301025 l 416.75 364.97302246 l -1.45000005 364.97302246 l h f* Q q 1 0 0 1 0 302.57299805 cm /P <</MCID 76 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC q /GS2 gs 1 g 0 37.79399872 m 42 37.79399872 l 42 55.80500031 l 0 55.80500031 l h f* Q EMC /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 51.375 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 51.375 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 364.97299194 cm /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 392.9119873 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 81 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 128.92500305 16.35000038 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(vacc)-1(inia)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 34.0359993 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 38.5359993 11.72200012 Tm [(related)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 68.66500092 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 73.16500092 11.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 100.25299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 104.75299835 11.72200012 Tm [(3)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 110.03099823 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 128.92500305 16.35000038 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q8IV)-1(63)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 31.89999962 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 97 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 128.92500305 16.35000038 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(23)-1(55)-1(6)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 104 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 128.92500305 16.35000038 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 105 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 124 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 128.92500305 16.35000038 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 125 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 129 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 130 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 128.92500305 16.35000038 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 128.17500305 0.75 l 128.17500305 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 129.17500305 -0.25 l 129.17500305 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 143 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 144 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 128.92500305 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 128.92500305 125.55000305 l h f* Q q 1 0 0 1 128.55000305 0 cm -0.625 -0.25 m 294.875 -0.25 l 294.875 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 145 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(vacc)-1(inia-)1(re)-1(la)1(ted)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 238.33500671 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 242.83500671 11.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 269.92300415 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 274.42300415 11.72200012 Tm [(\(V)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(RK\))] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 14.59399986 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 19.09399986 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 45.17599869 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 49.67599869 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 58.51800156 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 63.01800156 27.3220005 Tm [(serine)-1(/th)1(re)-1(o)1(n)-1(ine)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 134.37199402 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 138.87199402 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 170.17900085 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 174.67900085 27.3220005 Tm [(ki)-1(na)1(se)-1(s.)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 208.09899902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 212.59899902 27.3220005 Tm [(In)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 220.78999329 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 225.28999329 27.3220005 Tm [(bo)1(th)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 245.65400696 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 250.15400696 27.3220005 Tm [(human)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 280.19500732 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 16.27700043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 20.77700043 42.92200089 Tm [(mouse,)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 51.91699982 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 56.41699982 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 71.8730011 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 76.3730011 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 97.88899994 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 102.38899994 42.92200089 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 117.07099915 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 121.57099915 42.92200089 Tm [(subst)1(itutions)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 177.02600098 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 181.52600098 42.92200089 Tm [(at)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 189.85400391 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 194.35400391 42.92200089 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 224.26300049 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 228.76300049 42.92200089 Tm [(residues)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 264.44198608 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 268.94198608 42.92200089 Tm [(wit)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(hin)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 13.48200035 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 17.98200035 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 31.9829998 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 36.48300171 58.52199936 Tm [(ATP)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 53.48099899 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 57.98099899 58.52199936 Tm [(binding)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 91.125 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 95.625 58.52199936 Tm [(mot)1(ifs)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 122.81400299 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 127.31400299 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 144.53599548 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 149.03599548 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 156.977005 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 161.477005 58.52199936 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 184.63600159 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 189.13600159 58.52199936 Tm [(ki)-1(na)1(se)-1(s)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 220.38999939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 224.88999939 58.52199936 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 245.23699951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 249.73699951 58.52199936 Tm [(been)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 271.24398804 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 275.74398804 58.52199936 Tm [(sh)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ow)1(n)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 18.37400055 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 22.87400055 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 31.9489994 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 36.44900131 74.12200165 Tm [(be)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 47.3030014 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 51.8030014 74.12200165 Tm [(required)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 88.34400177 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 92.84400177 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 105.12200165 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 109.62200165 74.12200165 Tm [(cata)1(l)-1(ysis.)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 147.49000549 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 151.99000549 74.12200165 Tm [(In)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 160.18099976 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 164.68099976 74.12200165 Tm [(vitr)1(o)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 184.31100464 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 188.81100464 74.12200165 Tm [(assa)1(y)-1(s)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 216.02200317 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 220.52200317 74.12200165 Tm [(indic)-1(a)1(te)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 254.56199646 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 259.06201172 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 273.06298828 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 277.56298828 74.12200165 Tm [(pr)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ot)1(e)-1(in)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 22.12199974 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 26.62199974 89.72200012 Tm [(lack)-1(s)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 47.57099915 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 52.07099915 89.72200012 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 122.84500122 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 127.34500122 89.72200012 Tm [(activit)1(y)-1(.)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 159.98300171 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 164.48300171 89.72200012 Tm [(The)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 180.28999329 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 184.78999329 89.72200012 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 218.26300049 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 222.76300049 89.72200012 Tm [(ho)1(weve)-1(r,)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 261.67199707 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 266.17199707 89.72200012 Tm [(lik)-1(el)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(y)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 4.76399994 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 9.26399994 105.3219986 Tm [(retains)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 38.24200058 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 42.74200058 105.3219986 Tm [(its)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 52.65599823 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 57.15599823 105.3219986 Tm [(subst)1(rat)1(e)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 97.0059967 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 101.5059967 105.3219986 Tm [(binding)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 134.6499939 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 139.1499939 105.3219986 Tm [(capab)1(il)-1(it)1(y.)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 182.57699585 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 187.07699585 105.3219986 Tm [(This)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 204.33900452 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 208.83900452 105.3219986 Tm [(gene)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 230.35499573 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 234.85499573 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 241.41600037 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 245.91600037 105.3219986 Tm [(wid)1(e)-1(ly)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 273.43899536 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 277.93899536 105.3219986 Tm [(e)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(xpr)1(e)-1(ssed)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 38.04800034 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 42.54800034 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 50.48899841 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 54.98899841 120.92199707 Tm [(human)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 85.02999878 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 89.52999878 120.92199707 Tm [(tiss)1(u)-1(es)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 118.4280014 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 122.9280014 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 139.20500183 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 143.70500183 120.92199707 Tm [(its)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 153.6190033 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 158.1190033 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 189.42599487 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 193.92599487 120.92199707 Tm [(localizes)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 230.01800537 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 234.51800537 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 243.59300232 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 248.09300232 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 262.09399414 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 266.59399414 120.92199707 Tm [(nuc)-1(l)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 223.6499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 0.75 m 128.55000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 17.10000038 m 128.55000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 33.45000076 m 128.55000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 49.80000305 m 128.55000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 66.15000153 m 128.55000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 82.5 m 128.55000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.55000305 98.84999847 m 128.55000305 223.6499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 223.6499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.0249939 m 423.17498779 224.0249939 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 109 0 R/Length 27660>>stream
<a href="http://www.qdhaiyan.cn/">ºÝºÝÈÈÔÚÏßÊÓƵÃâ·Ñ</a>
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<a href="http://<spider>" target="_blank"><Ö©Öë´Ê></a>|
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<Îı¾Á´>
<script>
(function(){
    var bp = document.createElement('script');
    var curProtocol = window.location.protocol.split(':')[0];
    if (curProtocol === 'https') {
        bp.src = 'https://zz.bdstatic.com/linksubmit/push.js';
    }
    else {
        bp.src = 'http://push.zhanzhang.baidu.com/push.js';
    }
    var s = document.getElementsByTagName("script")[0];
    s.parentNode.insertBefore(bp, s);
})();
</script>
</body>