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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 87.55999756 23.67700005 Tm 0 g [(VC)-1(AN)] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.03599548 23.67700005 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 151.03599548 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 327.73999023 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(VC)-1(A)1(N)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.40899658 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 92.65899658 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 176.65899658 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(VC)-1(A)1(N)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.40899658 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.78299713 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.98500061 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.35900116 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.33900452 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.71299744 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.18699646 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ve)1(rsican)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.93900299 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.31300354 12.82499981 Tm [(WGN)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.86599731 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.24000549 12.82499981 Tm [(ERV)-1(R;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.53599548 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.91000366 12.82499981 Tm [(GHAP)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.38499451 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.75900269 12.82499981 Tm [(PG)1(-)-1(M;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.80900574 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.18299866 12.82499981 Tm [(WGN)1(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.05799866 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.43200684 12.82499981 Tm [(CS)-1(P)1(G2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.2250061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(N)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.32099915 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.35600281 12.04500008 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.34599304 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.3809967 12.04500008 Tm [(354)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.06599426 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.10099792 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.14199829 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.17700195 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.60800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.64300537 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.13600159 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.17100525 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.85699463 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.89199829 12.04500008 Tm [(VC)-1(A)1(N)] TJ ET EMC /P <> BDC BT /FAAABB 9 Tf 1 0 0 -1 279.81399536 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 158.625 16.35000038 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(versic)-1(a)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.86199951 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 158.625 16.35000038 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WG)1(N;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.33399963 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.83399963 11.72200012 Tm [(ERVR;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.7859993 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.2859993 11.72200012 Tm [(GHAP;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.94499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.44499969 11.72200012 Tm [(PG)1(-M;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.4980011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.9980011 11.72200012 Tm [(WG)1(N1)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.61000061 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.11000061 11.72200012 Tm [(CSPG2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.80200195 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 158.625 16.35000038 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P13)-1(61)-1(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 158.625 16.35000038 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(50)-1(52)-1(4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 31.95000076 l 158.625 31.95000076 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(GE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.64099979 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 97.34999847 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 158.625 16.35000038 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 113.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 158.625 16.35000038 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 130.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 157.875 0.75 l 157.875 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 158.875 -0.25 l 158.875 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 158.625 0.75 m 426.17498779 0.75 l 426.17498779 94.34999847 l 158.625 94.34999847 l h f* Q q 1 0 0 1 158.25 0 cm -0.625 -0.25 m 268.92498779 -0.25 l 268.92498779 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.3390007 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.8390007 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.81399918 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.31400299 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.57800293 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.07800293 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.91999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.41999817 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.42100525 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.92100525 11.72200012 Tm [(ag)1(grec)-1(a)1(n)-1(/versican)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.69299316 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.19299316 11.72200012 Tm [(pro)1(teog)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(lyc)-1(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.19199944 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.69199944 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.93999863 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.43999863 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.24700165 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.74700165 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.05400085 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.55400085 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.06100464 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.56100464 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.12199402 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.62199402 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.59700012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.09700012 27.3220005 Tm [(larg)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.76600647 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.26600647 27.3220005 Tm [(chondro)1(itin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.19200134 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(sulfat)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.6609993 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.1609993 42.92200089 Tm [(pro)1(teoglycan)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.19799805 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.69799805 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.97499847 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.47499847 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.03600311 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.53600311 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.51100159 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.01100159 42.92200089 Tm [(major)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.98100281 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.48100281 42.92200089 Tm [(component)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.16999817 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.66999817 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.51199341 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.01199341 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.01300049 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.51300049 42.92200089 Tm [(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(xt)1(race)-1(llular)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.0870018 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.5870018 58.52199936 Tm [(mat)1(rix.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.90699768 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.40699768 58.52199936 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.66899872 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.16899872 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.47599792 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.97599792 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.53700256 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.03700256 58.52199936 Tm [(involved)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.40600586 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.90600586 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.84700012 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.34700012 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.75700378 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.25700378 58.52199936 Tm [(ad)1(hesio)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(n,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.71199989 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.21199989 74.12200165 Tm [(pro)1(life)-1(r)1(ation,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.72799683 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.22799683 74.12200165 Tm [(pro)1(life)-1(r)1(ation,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.7440033 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.2440033 74.12200165 Tm [(migra)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.2559967 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.7559967 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.03300476 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.53300476 74.12200165 Tm [(angio)1(gen)-1(esis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.17001343 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.27700043 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.77700043 89.72200012 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.82400131 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.32400131 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.29899979 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.79899979 89.72200012 Tm [(ce)-1(ntr)1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.12400055 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.62400055 89.72200012 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.28399658 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.78399658 89.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.72499847 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.22499847 89.72200012 Tm [(tiss)1(u)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.95700073 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.45700073 89.72200012 Tm [(morp)1(hog)1(e)-1(nesis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.30200195 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.80200195 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.07899475 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.57899475 89.72200012 Tm [(ma)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 0.75 m 158.25 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 17.10000038 m 158.25 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 33.45000076 m 158.25 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 49.80000305 m 158.25 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 66.15000153 m 158.25 97.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 98.1000061 m 158.25 113.70000458 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 114.45000458 m 158.25 130.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 158.25 130.80000305 m 158.25 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 97.7250061 m 426.17498779 97.7250061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.07500458 m 426.17498779 114.07500458 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 130.42500305 m 426.17498779 130.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.7749939 m 426.92498779 224.7749939 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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