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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 -0.75 0 cm q -1 -1 m 389.79998779 -1 l 389.79998779 43.70000076 l -1 43.70000076 l h W n q 1 0 0 1 0.75 0.75 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 74.82800293 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [(U)-4(P)-4(K)-4(3)-4(A)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABD 22 Tf 1 0 0 -1 135.76800537 23.67700005 Tm [<0007>-4<0008>-4<0009>-4<000A>-4<000B>-4<000C>-4<000D>-4<000E>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABH 11 Tf 1 0 0 -1 312.47198486 19.63899994 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 42.70000076 cm /P <</MCID 3 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 30.76399994 Tm /GS2 gs 0 g [<000F0010001100120013>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 30.76399994 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 30.76399994 Tm [(UP)1(K3A)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 92.01300049 30.76399994 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 97.26300049 30.76399994 Tm [<000700080009000A000B000C000D000E>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 181.26300049 30.76399994 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 94.1780014 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<00140010001100120013>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(UP)1(K3A)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 92.01300049 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 94.38700104 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 127.58899689 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 129.96299744 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 189.94299316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 192.31700134 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 226.79100037 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 127.71700287 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<00110013>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(urop)-1(lakin)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 103.37000275 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 105.7440033 12.82499981 Tm [(3A)1(;)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 119.9509964 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 122.32499695 12.82499981 Tm [(UP)1(3A;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 148.69299316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 151.06700134 12.82499981 Tm [(UP)1(K3;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 176.81500244 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 179.18899536 12.82499981 Tm [(UP)1(III;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 202.09599304 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 204.47000122 12.82499981 Tm [(UP)1(IIIA)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 230.64300537 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 161.2559967 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<00160017001800150013>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00070008>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 194.79499817 cm /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0019>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001A0013>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001B001C0009>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAACA 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 228.33399963 m 416.75 228.33399963 l 416.75 259.53399658 l -1.45000005 259.53399658 l h f* Q q 1 0 0 1 0 228.33399963 cm /P <</MCID 49 >> BDC q 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAADA 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 259.53399658 cm /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 287.47299194 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 53 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(19-28)1(7)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 226.41799927 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 228.45300293 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 251.4940033 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 253.52900696 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 271.95999146 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 273.99499512 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 281.48800659 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 283.52301025 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 309.20901489 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 311.24398804 12.04500008 Tm [(UP)1(K3A)] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 336.11300659 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0 G 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0 G 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0 G 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0 G 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 g -1.45000005 316.4119873 m 416.75 316.4119873 l 416.75 347.61199951 l -1.45000005 347.61199951 l h f* Q q 1 g -1.45000005 347.61199951 m 416.75 347.61199951 l 416.75 378.81201172 l -1.45000005 378.81201172 l h f* Q q 1 0 0 1 0 316.4119873 cm /P <</MCID 81 >> BDC BT /FAAADA 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 82 >> BDC q /GS2 gs 1 g 0 37.79399872 m 42 37.79399872 l 42 55.80500031 l 0 55.80500031 l h f* Q EMC /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAACG 10.5 Tf 1 0 0 -1 0 51.375 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAADA 10.5 Tf 1 0 0 -1 42 51.375 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 378.81201172 cm /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 406.75100708 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(urop)1(l)-1(a)1(k)-1(in)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 40.6629982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 45.1629982 11.72200012 Tm [(3A)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 56.77299881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(UP)1(3)-1(A)1(;)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 26.00200081 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 30.50200081 11.72200012 Tm [(UP)1(K3)-1(;)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 55.88499832 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 60.38499832 11.72200012 Tm [(UP)1(III;)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 82.71399689 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 87.21399689 11.72200012 Tm [(UP)1(IIIA)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 113.70899963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 104 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 105 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 106 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(O75)-1(63)-1(1)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 108 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 111 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 112 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(BC0)-1(69)-1(54)-1(4)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 114 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 115 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 116 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 132 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 135 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 136 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 140 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 141 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 135.67500305 16.35000038 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 142 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q 1 g 0.375 0.75 m 134.92500305 0.75 l 134.92500305 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 135.92500305 -0.25 l 135.92500305 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 154 >> BDC BT /FAAADA 9 Tf 1 0 0 -1 0 42.92200089 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 155 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 135.67500305 0.75 m 422.42498779 0.75 l 422.42498779 78.75 l 135.67500305 78.75 l h f* Q q 1 0 0 1 135.30000305 0 cm -0.625 -0.25 m 288.125 -0.25 l 288.125 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAADD 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(urop)1(l)-1(a)1(k)-1(in)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 210.94000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 215.44000244 11.72200012 Tm [(fa)1(mi)-1(ly,)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 243.68800354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 248.18800354 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 253.16299438 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 257.66299438 11.72200012 Tm [(gr)1(ou)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(p)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 5.74800014 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 10.24800014 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 19.09000015 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 23.59000015 27.3220005 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 91.84999847 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 96.34999847 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 131.82299805 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 136.32299805 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 153.54499817 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 158.04499817 27.3220005 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 178.7559967 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 183.2559967 27.3220005 Tm [(complexe)-1(s)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 229.00700378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 233.50700378 27.3220005 Tm [(on)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 244.7749939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 249.2749939 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 263.27600098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 267.77600098 27.3220005 Tm [(ap)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ic)-1(a)1(l)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 14.27799988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 18.77799988 42.92200089 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 49.64099884 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 54.14099884 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 62.98300171 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 67.48300171 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 81.48400116 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 85.98400116 42.92200089 Tm [(blad)1(der)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 119.15799713 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 123.65799713 42.92200089 Tm [(epith)1(e)-1(lium.)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 171.84399414 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 176.34399414 42.92200089 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 220.19299316 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 224.69299316 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 232.63400269 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 237.13400269 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 252.58999634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 257.08999634 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 278.60598755 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(may)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 18.17099953 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 22.67099953 58.52199936 Tm [(be)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 33.52500153 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 38.02500153 58.52199936 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 83.15200043 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 87.65200043 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 106.04799652 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 110.54799652 58.52199936 Tm [(renal)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 132.0059967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 136.5059967 58.52199936 Tm [(ad)1(y)-1(sp)1(lasia.)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 182.98699951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 187.48699951 58.52199936 Tm [(Alt)1(e)-1(rna)1(tivel)-1(y)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 241.36799622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 245.86799622 58.52199936 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 275.94900513 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 40.92200089 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 45.42200089 74.12200165 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 78.99199677 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 83.49199677 74.12200165 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 103.83899689 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 108.33899689 74.12200165 Tm [(been)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 129.84599304 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 134.34599304 74.12200165 Tm [(described.)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 178.4980011 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 193.19999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 0.75 m 135.30000305 16.35000038 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 17.10000038 m 135.30000305 32.70000076 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 33.45000076 m 135.30000305 49.05000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 49.80000305 m 135.30000305 65.40000153 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 66.15000153 m 135.30000305 81.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 82.5 m 135.30000305 98.09999847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 98.84999847 m 135.30000305 114.44999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 135.30000305 115.19999695 m 135.30000305 193.19999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 193.19999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 98.47499847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 422.42498779 114.82499695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 193.57499695 m 423.17498779 193.57499695 l S Q Q q 1 0 0 1 0 600.70098877 cm /P <</MCID 242 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q 1 0 0 -1 0 841.90002441 cm 
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