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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 83.34899902 23.67700005 Tm 0 g [(TWSG1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 155.2460022 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 331.95001221 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(TWSG1)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 94.22799683 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 99.47799683 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 183.47799683 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 57.75 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TWSG1)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 94.22799683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 96.60199738 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 129.80400085 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 132.17799377 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 192.15800476 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 194.53199768 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 229.0059967 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(twisted)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 94.79699707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 97.17099762 12.82499981 Tm [(gastr)1(u)-1(lati)-1(on)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 148.36399841 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 150.73800659 12.82499981 Tm [(BMP)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 170.85099792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 173.2250061 12.82499981 Tm [(si)-1(g)1(n)-1(ali)-1(ng)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 210.50799561 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 212.88200378 12.82499981 Tm [(mod)-1(ulato)-1(r)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 257.99398804 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 260.36801147 12.82499981 Tm [(1;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 268.49899292 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 270.87298584 12.82499981 Tm [(TS)-1(G)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 287.43798828 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 134.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 52 >> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 273.63400269 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 56 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(26-22)1(3)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 226.41799927 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 228.45300293 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 251.4940033 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 253.52900696 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 271.95999146 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 273.99499512 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 281.48800659 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 283.52301025 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 309.20901489 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 311.24398804 12.04500008 Tm [(TWSG1)] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 338.01098633 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q /GS2 gs 1 g -1.45000005 302.57299805 m 416.75 302.57299805 l 416.75 333.77301025 l -1.45000005 333.77301025 l h f* Q q 1 0 0 1 0 302.57299805 cm /P <</MCID 84 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 333.77301025 m 416.75 333.77301025 l 416.75 364.97302246 l -1.45000005 364.97302246 l h f* Q q 1 0 0 1 0 333.77301025 cm /P <</MCID 85 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 364.97299194 cm /P <</MCID 88 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 392.9119873 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(tw)1(isted)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 31.23600006 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 35.73600006 11.72200012 Tm [(ga)1(strulat)1(ion)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 87.35399628 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 91.85399628 11.72200012 Tm [(BMP)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 111.8010025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 116.3010025 11.72200012 Tm [(signaling)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 155.23199463 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 159.73199463 11.72200012 Tm [(mod)1(u)-1(la)1(tor)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 205.07000732 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 209.57000732 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 214.8480072 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 105 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TSG)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 17.04599953 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9GZX9)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 35.96900177 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 116 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 117 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(20)-1(49)-1(0)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 119 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 120 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 140 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 141 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 145 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 146 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 137.17500305 16.35000038 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 147 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 159 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 160 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 109.94999695 l 137.17500305 109.94999695 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 161 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(May)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 18.53199959 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 23.03199959 11.72200012 Tm [(be)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 33.88600159 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 38.38600159 11.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 74.75499725 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 79.25499725 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 87.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 91.69599915 11.72200012 Tm [(do)1(rsoventra)1(l)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 146.03399658 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 150.53399658 11.72200012 Tm [(axis)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 166.6309967 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 171.1309967 11.72200012 Tm [(fo)1(rmatio)1(n)-1(.)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 215.99899292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 220.49899292 11.72200012 Tm [(Se)-1(ems)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 248.50500488 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 253.00500488 11.72200012 Tm [(to)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 262.07998657 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 266.57998657 11.72200012 Tm [(an)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ta)1(gonize)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 37.27899933 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 41.77899933 27.3220005 Tm [(BMP)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 61.72600174 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 66.22599792 27.3220005 Tm [(signaling)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 105.15699768 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 109.65699768 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 120.16899872 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 124.66899872 27.3220005 Tm [(fo)1(rmin)-1(g)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 159.07800293 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 163.57800293 27.3220005 Tm [(ternary)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 194.19500732 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 198.69500732 27.3220005 Tm [(complexe)-1(s)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 244.44599915 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 248.94599915 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 267.3420105 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 271.8420105 27.3220005 Tm [(C)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(HRD)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 19.69199944 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 24.19199944 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 40.46900177 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 44.96900177 42.92200089 Tm [(BMPs,)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 71.2480011 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 75.7480011 42.92200089 Tm [(th)1(e)-1(r)1(e)-1(by)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 108.80400085 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 113.30400085 42.92200089 Tm [(preventing)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 160.02200317 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 164.52200317 42.92200089 Tm [(BMPs)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 188.63499451 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 193.13499451 42.92200089 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 213.84599304 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 218.34599304 42.92200089 Tm [(binding)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 251.49000549 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 255.99000549 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 265.06500244 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 269.56500244 42.92200089 Tm [(th)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(eir)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 10.93799973 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 15.43799973 58.52199936 Tm [(rec)-1(ept)1(ors.)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 58.19200134 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 62.69200134 58.52199936 Tm [(In)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 70.88300323 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 75.38300323 58.52199936 Tm [(ad)1(dition)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 111.28199768 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 115.78199768 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 124.85700226 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 129.35699463 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 143.35800171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 147.85800171 58.52199936 Tm [(anti-)1(B)-1(MP)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 187.96699524 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 192.46699524 58.52199936 Tm [(func)-1(t)1(ion,)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 230.37399292 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 234.87399292 58.52199936 Tm [(also)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 252.1309967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 256.63101196 58.52199936 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 271.31298828 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(pro)1(-BMP)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 38.74700165 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 43.24700165 74.12200165 Tm [(activit)1(y)-1(,)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 75.88500214 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 80.38500214 74.12200165 Tm [(pa)1(rtly)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 105.05599976 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 109.55599976 74.12200165 Tm [(mediat)1(e)-1(d)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 150.43800354 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 154.93800354 74.12200165 Tm [(by)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 165.44999695 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 169.94999695 74.12200165 Tm [(cl)-1(eava)1(ge)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 207.50100708 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 212.00100708 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 228.27799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 232.77799988 74.12200165 Tm [(degra)1(dat)1(i)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(on)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 11.26799965 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 15.76799965 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 24.61000061 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 29.11000061 89.72200012 Tm [(CHRD,)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 56.98899841 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 61.48899841 89.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 86.58599854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 91.08599854 89.72200012 Tm [(rele)-1(a)1(se)-1(s)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 125.54399872 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 130.04400635 89.72200012 Tm [(BMPs)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 154.15699768 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 158.65699768 89.72200012 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 179.36799622 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 183.86799622 89.72200012 Tm [(ternary)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 214.48500061 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 218.98500061 89.72200012 Tm [(complexe)-1(s)1(.)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 266.90301514 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(May)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 18.53199959 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 23.03199959 105.3219986 Tm [(be)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 33.88600159 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 38.38600159 105.3219986 Tm [(an)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 48.9070015 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 53.4070015 105.3219986 Tm [(impor)1(tant)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 96.36799622 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 100.86799622 105.3219986 Tm [(mod)1(u)-1(la)1(tor)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 146.20599365 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 150.70599365 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 159.54800415 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 164.04800415 105.3219986 Tm [(BMP-regulat)1(e)-1(d)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 229.32000732 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 233.82000732 105.3219986 Tm [(cartilag)1(e)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 270.7250061 105.3219986 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 0.75 m 136.80000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 17.10000038 m 136.80000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 33.45000076 m 136.80000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 49.80000305 m 136.80000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 66.15000153 m 136.80000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 82.5 m 136.80000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 98.84999847 m 136.80000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 115.19999695 m 136.80000305 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w 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