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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 91.34700012 23.67700005 Tm 0 g [(TP63)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 136.24899292 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 147.24899292 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 323.95300293 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(TP63)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 84.18499756 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 89.43499756 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 173.43499756 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TP63)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 84.18499756 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 86.55899811 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 119.76100159 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 122.13500214 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 182.11500549 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 184.48899841 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 218.96299744 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(tumo)-1(r)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 89.6190033 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 93.22799683 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 124.61000061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 128.21899414 12.82499981 Tm [(p63;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 147.18899536 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 150.79800415 12.82499981 Tm [(AIS;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 167.15299988 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 170.76199341 12.82499981 Tm [(KET;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 189.27000427 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 192.8789978 12.82499981 Tm [(LMS)-1(;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 213.90499878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 217.51400757 12.82499981 Tm [(NB)1(P;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 238.23699951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 241.84599304 12.82499981 Tm [(RHS;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 261.72299194 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 265.33200073 12.82499981 Tm [(p40;)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 284.30200195 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 287.91101074 12.82499981 Tm [(p51;)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 306.88101196 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 310.48999023 12.82499981 Tm [(p63;)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 329.45999146 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 333.06900024 12.82499981 Tm [(EE)-1(C3;)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 357.05300903 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 360.6619873 12.82499981 Tm [(OF)-1(C8;)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 386.16900635 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 389.77801514 12.82499981 Tm [(p73H;)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 415.29000854 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [(p73L;)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 23.38400078 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 25.75799942 30.49699783 Tm [(SH)-1(FM4;)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 59.05799866 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 61.43199921 30.49699783 Tm [(TP53L;)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 89.83999634 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 92.21399689 30.49699783 Tm [(TP73L;)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 120.62200165 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 122.9960022 30.49699783 Tm [(p53CP;)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 152.98899841 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 155.36300659 30.49699783 Tm [(TP53CP)1(;)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 190.38000488 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 192.7539978 30.49699783 Tm [(B\(p)-1(5)1(1A\);)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 229.87800598 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 232.2519989 30.49699783 Tm [(B\(p)-1(5)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 251.98599243 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <</Lang (zh-CN) /MCID 76 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 77 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 260.37298584 cm /P <</MCID 83 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 288.31201172 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 84 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(95-34)1(4)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 226.41799927 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 228.45300293 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 251.4940033 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 253.52900696 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 271.95999146 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 273.99499512 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 281.48800659 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 283.52301025 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 309.20901489 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 311.24398804 12.04500008 Tm [(TP63)] TJ ET EMC /P <</MCID 111 >> BDC BT /FAAABB 9 Tf 1 0 0 -1 329.40200806 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 317.25100708 cm /P <</MCID 112 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <</Lang (zh-CN) /MCID 113 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 114 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 373.1289978 cm /P <</MCID 115 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 401.06799316 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 116 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ull)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 11.15799999 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 15.65799999 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 119 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 43.33499908 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 120.67500305 16.35000038 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 120 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(tumor)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 26.48999977 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 30.98999977 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 62.29700089 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 66.79699707 11.72200012 Tm [(p63)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 83.10099792 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 126 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 127 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 31.95000076 l 120.67500305 31.95000076 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 128 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(AIS;)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 16.3390007 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 20.8390007 11.72200012 Tm [(KET;)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 38.82600021 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 43.32600021 11.72200012 Tm [(LMS;)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 64.09899902 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 68.59899902 11.72200012 Tm [(NBP;)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 89.23600006 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 93.73600006 11.72200012 Tm [(RHS;)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 113.93299866 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 118.43299866 11.72200012 Tm [(p40)-1(;)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 136.90299988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 141.40299988 11.72200012 Tm [(p51)-1(;)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 159.8730011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 164.3730011 11.72200012 Tm [(p63)-1(;)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 182.84300232 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 187.34300232 11.72200012 Tm [(EEC3;)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 210.70399475 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 215.20399475 11.72200012 Tm [(OFC8)-1(;)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 240.78500366 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 245.28500366 11.72200012 Tm [(p73)-1(H;)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 270.71600342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 275.21600342 11.72200012 Tm [(p73)-1(L;)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 298.30499268 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(SH)-1(FM4;)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 33.17399979 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 37.67399979 27.3220005 Tm [(TP53)-1(L;)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 65.68000031 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 70.18000031 27.3220005 Tm [(TP73)-1(L;)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 98.18599701 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 102.68599701 27.3220005 Tm [(p53)-1(C)1(P;)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 132.68299866 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 137.18299866 27.3220005 Tm [(TP53)-1(CP;)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 172.0980072 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 176.5980072 27.3220005 Tm [(B\(p5)-1(1A\);)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 213.05900574 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 217.55900574 27.3220005 Tm [(B\(p5)-1(1B\))] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 251.16799927 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 48.29999924 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 166 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 167 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 120.67500305 16.35000038 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 168 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9H)-1(3D4)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 36.98400116 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 64.65000153 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 170 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 173 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 120.67500305 16.35000038 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 174 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(NP_00)-1(13)-1(16)-1(074)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 64.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 176 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 177 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 120.67500305 16.35000038 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 178 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 97.34999847 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 194 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 197 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 120.67500305 16.35000038 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 198 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 113.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 202 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 203 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 120.67500305 16.35000038 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 204 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 130.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 119.92500305 0.75 l 119.92500305 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 120.92500305 -0.25 l 120.92500305 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 216 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 217 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 120.67500305 0.75 m 426.17498779 0.75 l 426.17498779 78.75 l 120.67500305 78.75 l h f* Q q 1 0 0 1 120.30000305 0 cm -0.625 -0.25 m 306.875 -0.25 l 306.875 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 218 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(p53)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 186.58099365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 191.08099365 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 217.16299438 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 221.66299438 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 230.50500488 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 235.00500488 11.72200012 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 289.58898926 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 294.08898926 11.72200012 Tm [(f)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(acto)1(rs.)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 28.33200073 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 32.83200073 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 48.63899994 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 53.13899994 27.3220005 Tm [(func)-1(t)1(ional)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 96.24900055 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 100.74900055 27.3220005 Tm [(do)1(mains)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 137.74200439 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 142.24200439 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 151.08399963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 155.58399963 27.3220005 Tm [(p53)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 171.88800049 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 176.38800049 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 202.47000122 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 206.97000122 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 242.44299316 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 246.94299316 27.3220005 Tm [(inc)-1(lude)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 278.20098877 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 282.70098877 27.3220005 Tm [(an)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 293.22198486 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(N-t)1(e)-1(r)1(mi)-1(na)1(l)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 46.84999847 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 51.34999847 42.92200089 Tm [(tr)1(ansactivat)1(ion)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 114.77600098 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 119.27600098 42.92200089 Tm [(do)1(main,)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 154.27000427 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 158.77000427 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 163.74499512 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 168.24499512 42.92200089 Tm [(ce)-1(ntr)1(al)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 197.57000732 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 202.07000732 42.92200089 Tm [(DNA)1(-binding)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 259.61199951 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 264.11199951 42.92200089 Tm [(do)1(main)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 296.93899536 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 16.27700043 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 20.77700043 58.52199936 Tm [(an)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 31.29800034 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 35.79800034 58.52199936 Tm [(oligo)1(me)-1(riz)1(ation)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 103.57499695 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 108.07499695 58.52199936 Tm [(do)1(main.)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 143.06900024 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 147.56900024 58.52199936 Tm [(Alt)1(e)-1(rna)1(tive)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 194.29200745 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 198.79200745 58.52199936 Tm [(splicin)-1(g)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 231.70700073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 236.20700073 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 245.04899597 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 249.54899597 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 265.00500488 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 269.50500488 58.52199936 Tm [(gene)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 291.02099609 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 16.27700043 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 20.77700043 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 34.77799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 39.27799988 74.12200165 Tm [(use)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 54.09600067 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 58.59600067 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 67.43800354 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 71.93800354 74.12200165 Tm [(alt)1(e)-1(rnat)1(ive)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 117.3030014 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 121.8030014 74.12200165 Tm [(pro)1(moters)] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 166.92599487 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 171.42599487 74.12200165 Tm [(results)] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 199.59500122 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 204.09500122 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 212.03599548 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 216.53599548 74.12200165 Tm [(multiple)] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 251.90800476 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 256.4079895 74.12200165 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 297.32998657 74.12200165 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.80000305 l S Q q /GS1 gs 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0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 48.67500305 m 426.17498779 48.67500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.02500153 m 426.17498779 65.02500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 81.375 m 426.17498779 81.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 97.72499847 m 426.17498779 97.72499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.07499695 m 426.17498779 114.07499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 130.42500305 m 426.17498779 130.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17500305 m 426.92498779 209.17500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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