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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 65.14099884 23.67700005 Tm 0 g [(TMPRSS13)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 162.45399475 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 173.45399475 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 350.1579895 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(TMPRSS)-1(13)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 108.51200104 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 113.76200104 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 197.76199341 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TMPRSS)-1(13)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 108.51200104 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 110.88600159 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 144.08799744 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 146.46200562 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 206.44200134 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 208.81599426 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 243.28999329 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(transme)1(mb)-1(r)1(an)-1(e)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 131.77799988 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 134.1519928 12.82499981 Tm [(protease,)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 174.58799744 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 176.96200562 12.82499981 Tm [(ser)1(i)-1(ne)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 203.10400391 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 205.47799683 12.82499981 Tm [(13;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 218.93099976 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 221.30499268 12.82499981 Tm [(MSP;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 243.34100342 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 245.71499634 12.82499981 Tm [(MSPL;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 272.16500854 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 274.53900146 12.82499981 Tm [(MSPS)-1(;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 301.39898682 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 303.77301025 12.82499981 Tm [(TMPRSS)-1(11)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 349.28500366 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 55 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 56 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(C)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 124.30999756 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 126.34500122 12.04500008 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 157.33500671 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 159.36999512 12.04500008 Tm [(262)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 173.05499268 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 175.08999634 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 198.1309967 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 200.16600037 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 218.59700012 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 220.63200378 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 228.125 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 230.16000366 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 255.84599304 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 257.88101196 12.04500008 Tm [(TMPRSS)-1(13)] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAABB 9 Tf 1 0 0 -1 296.89099121 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 80 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 81 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 83 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 84 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 119.92500305 16.35000038 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 68.26000214 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 72.76000214 11.72200012 Tm [(pro)1(tease,)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 112.53900146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 117.03900146 11.72200012 Tm [(serine)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 142.79499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 147.29499817 11.72200012 Tm [(13)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 157.85099792 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 33.45000076 l 0.375 33.45000076 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 34.45000076 l -0.625 34.45000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 20.27199936 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 97 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 20.27199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 33.45000076 l 119.92500305 33.45000076 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 34.45000076 l -0.625 34.45000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 98 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 20.27199936 Tm /GS2 gs 0.13333334 g [(MSP;)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 21.6609993 20.27199936 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 26.1609993 20.27199936 Tm [(MSPL;)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 52.43999863 20.27199936 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 56.93999863 20.27199936 Tm [(MSPS;)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 83.79499817 20.27199936 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 88.29499817 20.27199936 Tm [(TMPRSS1)-1(1)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 134.57400513 20.27199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.79999924 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 106 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 107 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 119.92500305 16.35000038 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 108 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9B)-1(Y)1(E2)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 33.91699982 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 66.15000153 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 110 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 113 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 119.92500305 16.35000038 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 114 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC1)-1(14)-1(92)-1(8)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 82.5 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 116 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 117 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 119.92500305 16.35000038 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 118 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.84999847 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 134 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 137 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 119.92500305 16.35000038 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 138 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 115.19999695 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 142 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 143 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 119.92500305 16.35000038 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 144 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 131.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 119.17500305 0.75 l 119.17500305 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 120.17500305 -0.25 l 120.17500305 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 157 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 119.92500305 0.75 m 426.17498779 0.75 l 426.17498779 78.75 l 119.92500305 78.75 l h f* Q q 1 0 0 1 119.55000305 0 cm -0.625 -0.25 m 307.625 -0.25 l 307.625 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 158 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(type)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 189.2480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 193.7480011 11.72200012 Tm [(II)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 199.03900146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 203.53900146 11.72200012 Tm [(tr)1(ansme)-1(mb)1(rane)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 271.79901123 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 276.29901123 11.72200012 Tm [(serin)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 5.10599995 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 9.60599995 27.3220005 Tm [(pro)1(tease)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 47.21900177 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 51.71900177 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 79.96700287 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 84.46700287 27.3220005 Tm [(Transmembrane)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 154.53300476 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 159.03300476 27.3220005 Tm [(serine)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 184.78900146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 189.28900146 27.3220005 Tm [(pro)1(teases)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 231.06799316 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 235.56799316 27.3220005 Tm [(are)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 249.08599854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 253.58599854 27.3220005 Tm [(regulat)1(e)-1(d)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 295.01800537 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 10.51200008 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 15.01200008 42.92200089 Tm [(pro)1(tease)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 52.625 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 57.125 42.92200089 Tm [(inhibito)1(rs)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 97.82299805 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 102.32299805 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 118.59999847 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 123.09999847 42.92200089 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 151.91900635 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 156.41900635 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 165.4940033 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 169.9940033 42.92200089 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 205.73500061 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 210.23500061 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 218.17599487 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 222.67599487 42.92200089 Tm [(development,)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 281.83999634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 286.33999634 42.92200089 Tm [(ho)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(meosta)1(sis,)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 44.64799881 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 49.14799881 58.52199936 Tm [(infec)-1(t)1(i)-1(o)1(n,)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 89.01100159 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 93.51100159 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 109.78800201 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 114.28800201 58.52199936 Tm [(tumor)1(ige)-1(nesis.)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 177.58200073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 182.08200073 58.52199936 Tm [(Multiple)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 217.81399536 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 222.31399536 58.52199936 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 263.23599243 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 267.73599243 58.52199936 Tm [(var)1(i)-1(a)1(n)-1(t)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(s)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 4.16599989 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 8.66600037 74.12200165 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 49.00799942 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 53.50799942 74.12200165 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 90.44799805 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 94.94799805 74.12200165 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 132.10800171 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 136.60800171 74.12200165 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 156.95500183 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 161.45500183 74.12200165 Tm [(been)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 182.96200562 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 187.46200562 74.12200165 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 213.1519928 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 217.6519928 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 229.92999268 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 234.42999268 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 249.88600159 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 254.38600159 74.12200165 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 278.06799316 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 210.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 0.75 m 119.55000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 17.10000038 m 119.55000305 49.80000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 50.55000305 m 119.55000305 66.15000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 66.90000153 m 119.55000305 82.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 83.25 m 119.55000305 98.84999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 99.59999847 m 119.55000305 115.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 115.94999695 m 119.55000305 131.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 119.55000305 132.30000305 m 119.55000305 210.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 210.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 50.17500305 m 426.17498779 50.17500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 66.52500153 m 426.17498779 66.52500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.875 m 426.17498779 82.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 99.22499847 m 426.17498779 99.22499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 115.57499695 m 426.17498779 115.57499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 131.92500305 m 426.17498779 131.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 210.67500305 m 426.92498779 210.67500305 l S Q Q q 1 0 0 1 0 594.17901611 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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