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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 75.47499847 23.67700005 Tm 0 g [(THEMI)1(S2)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 163.1210022 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 339.82501221 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(THE)-1(MIS2)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 101.55500031 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 106.80500031 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 190.80499268 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(THE)-1(MIS2)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 101.55500031 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 103.92900085 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 137.1309967 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 139.50500488 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 199.48500061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 201.85899353 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 236.33299255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(thymocyte)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 108.64499664 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 111.01899719 12.82499981 Tm [(selection)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 149.40400696 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 151.77799988 12.82499981 Tm [(asso)-1(c)1(i)-1(ate)1(d)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 196.69500732 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 199.06900024 12.82499981 Tm [(fami)-1(ly)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 225.26300049 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 227.63699341 12.82499981 Tm [(me)1(mb)-1(e)1(r)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 264.03799438 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 266.4119873 12.82499981 Tm [(2;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 274.54299927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 276.91699219 12.82499981 Tm [(ICB-1;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 302.21899414 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 304.59298706 12.82499981 Tm [(C1orf38)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 338.55899048 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 214.49499512 m 416.75 214.49499512 l 416.75 245.69499207 l -1.45000005 245.69499207 l h f* Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 52 >> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 273.63400269 m 416.75 273.63400269 l 416.75 291.57299805 l -1.45000005 291.57299805 l h f* Q q 1 0 0 1 0 273.63400269 cm /P <</MCID 56 >> BDC q /GS2 gs 1 g 0 1.25 m 28.15600014 1.25 l 28.15600014 16.68799973 l 0 16.68799973 l h f* Q q /GS2 gs 1 g 28.15600014 1.25 m 30.81900024 1.25 l 30.81900024 16.68799973 l 28.15600014 16.68799973 l h f* Q q /GS2 gs 1 g 30.81900024 1.25 m 62.12599945 1.25 l 62.12599945 16.68799973 l 30.81900024 16.68799973 l h f* Q q /GS2 gs 1 g 62.12599945 1.25 m 64.78900146 1.25 l 64.78900146 16.68799973 l 62.12599945 16.68799973 l h f* Q q /GS2 gs 1 g 64.78900146 1.25 m 127.63999939 1.25 l 127.63999939 16.68799973 l 64.78900146 16.68799973 l h f* Q q /GS2 gs 1 g 127.63999939 1.25 m 130.30299377 1.25 l 130.30299377 16.68799973 l 127.63999939 16.68799973 l h f* Q q /GS2 gs 1 g 130.30299377 1.25 m 139.37799072 1.25 l 139.37799072 16.68799973 l 130.30299377 16.68799973 l h f* Q q /GS2 gs 1 g 139.37800598 1.25 m 142.04100037 1.25 l 142.04100037 16.68799973 l 139.37800598 16.68799973 l h f* Q q /GS2 gs 1 g 142.04100037 1.25 m 149.35800171 1.25 l 149.35800171 16.68799973 l 142.04100037 16.68799973 l h f* Q q /GS2 gs 1 g 149.35800171 1.25 m 152.02099609 1.25 l 152.02099609 16.68799973 l 149.35800171 16.68799973 l h f* Q q /GS2 gs 1 g 152.02099609 1.25 m 187.66099548 1.25 l 187.66099548 16.68799973 l 152.02099609 16.68799973 l h f* Q q /GS2 gs 1 g 187.66099548 1.25 m 190.32398987 1.25 l 190.32398987 16.68799973 l 187.66099548 16.68799973 l h f* Q q /GS2 gs 1 g 190.32400513 1.25 m 206.15701294 1.25 l 206.15701294 16.68799973 l 190.32400513 16.68799973 l h f* Q q /GS2 gs 1 g 206.15699768 1.25 m 208.81999207 1.25 l 208.81999207 16.68799973 l 206.15699768 16.68799973 l h f* Q q /GS2 gs 1 g 208.82000732 1.25 m 235.89001465 1.25 l 235.89001465 16.68799973 l 208.82000732 16.68799973 l h f* Q q /GS2 gs 1 g 235.88999939 1.25 m 238.55299377 1.25 l 238.55299377 16.68799973 l 235.88999939 16.68799973 l h f* Q q /GS2 gs 1 g 238.55299377 1.25 m 260.35900879 1.25 l 260.35900879 16.68799973 l 238.55299377 16.68799973 l h f* Q q /GS2 gs 1 g 260.35900879 1.25 m 263.02200317 1.25 l 263.02200317 16.68799973 l 260.35900879 16.68799973 l h f* Q q /GS2 gs 1 g 263.02200317 1.25 m 271.86401367 1.25 l 271.86401367 16.68799973 l 263.02200317 16.68799973 l h f* Q q /GS2 gs 1 g 271.86401367 1.25 m 274.52700806 1.25 l 274.52700806 16.68799973 l 271.86401367 16.68799973 l h f* Q q /GS2 gs 1 g 274.52700806 1.25 m 304.56799316 1.25 l 304.56799316 16.68799973 l 274.52700806 16.68799973 l h f* Q q /GS2 gs 1 g 304.56799316 1.25 m 307.23098755 1.25 l 307.23098755 16.68799973 l 304.56799316 16.68799973 l h f* Q q /GS2 gs 1 g 307.23098755 1.25 m 346.20999146 1.25 l 346.20999146 16.68799973 l 307.23098755 16.68799973 l h f* Q EMC /P <</MCID 57 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 12.89099979 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 28.15600014 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 30.81900024 12.89099979 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 62.12599945 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 64.78900146 12.89099979 Tm [(correspond)1(i)-1(ng)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 127.63999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 130.30299377 12.89099979 Tm [(to)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 139.37800598 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 142.04100037 12.89099979 Tm [(N)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 149.35800171 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 152.02099609 12.89099979 Tm [(terminal)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 187.66099548 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 190.32400513 12.89099979 Tm [(15)-1(0)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 206.15699768 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 208.82000732 12.89099979 Tm [(amino)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 235.88999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 238.55299377 12.89099979 Tm [(acids)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 260.35900879 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 263.02200317 12.89099979 Tm [(of)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 271.86401367 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 274.52700806 12.89099979 Tm [(human)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 304.56799316 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 307.23098755 12.89099979 Tm [(TH)-1(E)1(M)-1(I)1(S)-1(2)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 346.20999146 12.89099979 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 291.57299805 m 416.75 291.57299805 l 416.75 322.77301025 l -1.45000005 322.77301025 l h f* Q q 1 0 0 1 0 291.57299805 cm /P <</MCID 81 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 322.77301025 m 416.75 322.77301025 l 416.75 353.97302246 l -1.45000005 353.97302246 l h f* Q q 1 0 0 1 0 322.77301025 cm /P <</MCID 82 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 353.97299194 cm /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 381.9119873 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(th)1(y)-1(mo)1(c)-1(yte)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 45.54899979 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 50.04899979 11.72200012 Tm [(sele)-1(ction)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 88.35199738 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 92.85199738 11.72200012 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 137.97900391 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 142.47900391 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 168.56100464 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 173.06100464 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 209.32499695 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 213.82499695 11.72200012 Tm [(2)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 219.10299683 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 103 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 104 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ICB-1;)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 25.65099907 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 30.15099907 11.72200012 Tm [(C1orf38)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 64.28299713 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 108 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 109 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 110 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q5T)-1(E)1(J8)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 31.56200027 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 112 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 115 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 116 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC1)-1(32)-1(69)-1(2)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 118 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 119 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 120 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 136 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 139 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 140 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 144 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 145 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 146 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 158 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 159 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 140.17500305 31.95000076 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 160 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(May)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 18.53199959 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 23.03199959 11.72200012 Tm [(constitut)1(e)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 66.08499908 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 70.58499908 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 75.55999756 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 80.05999756 11.72200012 Tm [(control)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 110.74700165 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 115.24700165 11.72200012 Tm [(po)1(i)-1(nt)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 138.01100159 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 142.51100159 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 150.45199585 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 154.95199585 11.72200012 Tm [(macrop)1(hage)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 209.15899658 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 213.65899658 11.72200012 Tm [(inflammat)1(ory)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 271.20498657 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(response,)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 41.16400146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 45.66400146 27.3220005 Tm [(pro)1(moting)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 91.77600098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 96.27600098 27.3220005 Tm [(LPS-induce)-1(d)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 150.10899353 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 154.60899353 27.3220005 Tm [(TNF)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 171.86599731 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 176.36599731 27.3220005 Tm [(pro)1(duc)-1(t)1(ion.)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 226.27000427 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 146.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 0.75 m 139.80000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 17.10000038 m 139.80000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 33.45000076 m 139.80000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 49.80000305 m 139.80000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 66.15000153 m 139.80000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 82.5 m 139.80000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 98.84999847 m 139.80000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 115.19999695 m 139.80000305 146.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 146.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 422.42498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 146.7749939 m 423.17498779 146.7749939 l S Q Q q 1 0 0 1 0 529.06201172 cm /P <</MCID 186 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 557.00097656 cm /P <</MCID 187 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 584.94000244 cm /P <</MCID 188 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm [( )] TJ ET EMC Q Q 1 0 0 -1 0 841.90002441 cm 
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