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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 91.51799774 23.67700005 Tm 0 g [(STX7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.07699585 23.67700005 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 147.07699585 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 323.78100586 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(ST)-1(X7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.71299744 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 88.96299744 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 172.96299744 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ST)-1(X7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.71299744 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.08699799 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.28900146 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.66300201 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.64300537 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.01699829 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.49099731 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(syntaxi)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.39600372 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.76999664 12.82499981 Tm [(7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.09200287 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.30999756 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.34500122 12.04500008 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.33500671 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.36999512 12.04500008 Tm [(131)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.05499268 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.08999634 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.1309967 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.16600037 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.59700012 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.63200378 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.125 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.16000366 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.84599304 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.88101196 12.04500008 Tm [(ST)-1(X7)] TJ ET EMC /P <> BDC BT /FAAABB 9 Tf 1 0 0 -1 275.63500977 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 114.72499847 16.35000038 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(syntaxin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.30599976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.80599976 11.72200012 Tm [(7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.08399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 114.72499847 16.35000038 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(O15)-1(40)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 114.72499847 16.35000038 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(11)-1(97)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 114.72499847 16.35000038 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 114.72499847 16.35000038 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 114.72499847 16.35000038 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 113.97499847 0.75 l 113.97499847 63.15000153 l 0.375 63.15000153 l h f* Q q -0.625 -0.25 m 114.97499847 -0.25 l 114.97499847 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 35.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 35.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.72499847 0.75 m 426.17501831 0.75 l 426.17501831 63.15000153 l 114.72499847 63.15000153 l h f* Q q 1 0 0 1 114.34999847 0 cm -0.625 -0.25 m 312.82501221 -0.25 l 312.82501221 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(May)] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.53199959 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.03199959 11.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.88600159 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.38600159 11.72200012 Tm [(involved)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.75499725 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.25499725 11.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.19599915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.69599915 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.00299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.50299835 11.72200012 Tm [(tr)1(aff)1(i)-1(cki)-1(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.01300049 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.51300049 11.72200012 Tm [(fro)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.22399902 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.72399902 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.7250061 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.2250061 11.72200012 Tm [(plas)1(ma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.91600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.41600037 11.72200012 Tm [(membrane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.20001221 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.07499981 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.57499981 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.57600021 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.07600021 27.3220005 Tm [(early)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.7519989 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.2519989 27.3220005 Tm [(en)-1(d)1(osome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.80999756 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.30999756 27.3220005 Tm [(\(EE\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.21800232 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.71800232 27.3220005 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.85899353 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.35899353 27.3220005 Tm [(well)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.36099243 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.86099243 27.3220005 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.0019989 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.5019989 27.3220005 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.44299316 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.94299316 27.3220005 Tm [(ho)1(motypic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.13400269 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.63400269 27.3220005 Tm [(fusion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.1289978 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.6289978 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.4710083 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.9710083 27.3220005 Tm [(en)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ocy)-1(t)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.26000023 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.76000023 42.92200089 Tm [(org)1(ane)-1(lles.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.53099823 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.03099823 42.92200089 Tm [(Mediat)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.68299866 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.18299866 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.18400574 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.68400574 42.92200089 Tm [(en)-1(d)1(ocy)-1(t)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.35299683 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.85299683 42.92200089 Tm [(tr)1(aff)1(i)-1(ck)-1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.36300659 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.86300659 42.92200089 Tm [(fro)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.57400513 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.07400513 42.92200089 Tm [(early)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.75 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.25 42.92200089 Tm [(en)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(oso)1(me)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.31499863 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.81499863 58.52199936 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.88999939 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.38999939 58.52199936 Tm [(lat)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.21900177 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.71900177 58.52199936 Tm [(en)-1(d)1(osomes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.44300079 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.94300079 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.22000122 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.72000122 58.52199936 Tm [(lysosomes.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.52600098 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 161.25 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 0.75 m 114.34999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 17.10000038 m 114.34999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 33.45000076 m 114.34999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 49.80000305 m 114.34999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 66.15000153 m 114.34999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 82.5 m 114.34999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 114.34999847 98.84999847 m 114.34999847 161.25 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 161.25 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17501831 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17501831 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17501831 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17501831 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17501831 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17501831 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 161.625 m 426.92501831 161.625 l S Q Q q 1 0 0 1 0 545.12902832 cm Q Q 1 0 0 -1 0 841.90002441 cm
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