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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 77.78500366 23.67700005 Tm 0 g [(STARD8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.81100464 23.67700005 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 160.81100464 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 337.51501465 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(ST)-1(A)1(RD)-1(8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 101.75 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 185.75 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ST)-1(A)1(RD)-1(8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.87400055 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.07600403 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.44999695 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.42999268 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.80400085 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.27799988 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(StAR-re)1(l)-1(ate)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.91500092 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.55699921 12.82499981 Tm [(li)-1(pi)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.81900024 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.46099854 12.82499981 Tm [(transfer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.3809967 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.022995 12.82499981 Tm [(\(S)-1(TART\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.2250061 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.86700439 12.82499981 Tm [(do)-1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.26400757 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.90600586 12.82499981 Tm [(con)-1(taini)-1(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.74099731 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 319.38299561 12.82499981 Tm [(8;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 327.51400757 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 334.15600586 12.82499981 Tm [(DL)-1(C3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 358.76000977 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 365.40200806 12.82499981 Tm [(ARHG)1(AP38)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29800415 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(ST)-1(A)1(RT)-1(GA)1(P3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.27999878 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 260.37298584 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 288.31201172 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.30999756 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.34500122 12.04500008 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.33500671 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.36999512 12.04500008 Tm [(223)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.05499268 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.08999634 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.1309967 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.16600037 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.59700012 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.63200378 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.125 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.16000366 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.84599304 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.88101196 12.04500008 Tm [(ST)-1(A)1(RD)-1(8)] TJ ET EMC /P <> BDC BT /FAAABB 9 Tf 1 0 0 -1 286.59500122 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 317.25100708 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 373.1289978 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 401.06799316 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(StA)1(R-relat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.77799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.27799988 11.72200012 Tm [(lipid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.96800232 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.46800232 11.72200012 Tm [(tr)1(ansfer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.60700226 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.10700226 11.72200012 Tm [(\(START\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.83900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.33900452 11.72200012 Tm [(do)1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.16600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.66600037 11.72200012 Tm [(containing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.41299438 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.91299438 11.72200012 Tm [(8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.19099426 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(DLC3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.93899918 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.43899918 11.72200012 Tm [(AR)1(H)-1(GA)1(P38)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.86199951 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.36199951 11.72200012 Tm [(STARTGA)1(P3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.89199829 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q92)-1(50)-1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(35)-1(58)-1(7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 126.67500305 16.35000038 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 125.92500305 0.75 l 125.92500305 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 126.92500305 -0.25 l 126.92500305 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 126.67500305 0.75 m 426.17498779 0.75 l 426.17498779 78.75 l 126.67500305 78.75 l h f* Q q 1 0 0 1 126.30000305 0 cm -0.625 -0.25 m 300.875 -0.25 l 300.875 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.75100708 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.25100708 11.72200012 Tm [(subf)1(amily)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.79299927 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.29299927 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.13499451 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.63499451 11.72200012 Tm [(Rho)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.77400208 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.27400208 11.72200012 Tm [(GTPa)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.8789978 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.3789978 11.72200012 Tm [(act)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ivat)1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.14500046 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.64500046 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.11799622 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.61799622 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.83999634 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.33999634 27.3220005 Tm [(contain)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.38899994 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.88900757 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.86399841 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.36399841 27.3220005 Tm [(st)1(e)-1(ro)1(i)-1(d)1(ogenic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.33900452 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.83900452 27.3220005 Tm [(acute)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.33200073 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.83200073 27.3220005 Tm [(regulat)1(ory)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.32199097 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.82199097 27.3220005 Tm [(pr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ot)1(e)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.12199974 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.62199974 42.92200089 Tm [(related)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.75099945 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.25099945 42.92200089 Tm [(lipid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.94100189 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.44100189 42.92200089 Tm [(tr)1(ansfer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.58000183 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.08000183 42.92200089 Tm [(do)1(main.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.07400513 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.57400513 42.92200089 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.3809967 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.8809967 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.38800049 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.88800049 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.19500732 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.69500732 42.92200089 Tm [(localize)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.16599989 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.66600037 58.52199936 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.74099922 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.24099922 58.52199936 Tm [(fo)1(c)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.9659996 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.4659996 58.52199936 Tm [(ad)1(hesions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.83999634 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.33999634 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.61699677 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.11699677 58.52199936 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.28799438 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.78799438 58.52199936 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.64199829 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.14199829 58.52199936 Tm [(involved)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.51100159 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.01100159 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.95199585 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.45199585 58.52199936 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.71800232 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.21798706 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.62799072 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.12799072 58.52199936 Tm [(mor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ph)1(ology.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.81499863 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.31499863 74.12200165 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.57699966 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.07700348 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.38400269 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.88400269 74.12200165 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.05500031 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.55500031 74.12200165 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.81199646 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.31199646 74.12200165 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.05299377 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.55299377 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.69400024 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.19400024 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.16900635 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.66900635 74.12200165 Tm [(tumor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.15899658 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.65899658 74.12200165 Tm [(supp)1(re)-1(ss)1(or.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.06698608 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 0.75 m 126.30000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 17.10000038 m 126.30000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 33.45000076 m 126.30000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 49.80000305 m 126.30000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 66.15000153 m 126.30000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 82.5 m 126.30000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 98.84999847 m 126.30000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 126.30000305 115.19999695 m 126.30000305 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 193.57499695 m 426.92498779 193.57499695 l S Q Q q 1 0 0 1 0 595.01800537 cm Q Q 1 0 0 -1 0 841.90002441 cm
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