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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 81.02300262 23.67700005 Tm 0 g [(SHMT2)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 146.57200623 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 157.57200623 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 334.27600098 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(SH)-1(MT2)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 83.28199768 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 88.53199768 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 172.53199768 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(SH)-1(M)1(T)-1(2)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 93.78199768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 96.15599823 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 131.73199463 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 191.71200562 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 194.08599854 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 228.55999756 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ser)1(i)-1(ne)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 89.14199829 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 91.51599884 12.82499981 Tm [(hydrox)-1(y)1(met)1(h)-1(yltransfer)1(as)-1(e)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 203.88900757 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 206.26300049 12.82499981 Tm [(2;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 214.39399719 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 216.76800537 12.82499981 Tm [(GLY)-1(A)1(;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 241.80799866 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 244.18200684 12.82499981 Tm [(SH)-1(MT;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 272.45199585 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 274.82598877 12.82499981 Tm [(HEL)-1(-S-)-1(5)1(1e)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 318.03100586 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 50 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 51 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(305-5)1(04)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(SH)-1(M)1(T)-1(2)] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAABB 9 Tf 1 0 0 -1 342.19100952 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 79 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 82 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(serine)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 25.75600052 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 30.25600052 11.72200012 Tm [(hydro)1(xyme)-1(t)1(hyltransf)1(e)-1(ra)1(se)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 141.77999878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 146.27999878 11.72200012 Tm [(2)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 151.55799866 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(GLY)1(A;)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 25.24200058 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 29.74200058 11.72200012 Tm [(SH)-1(MT;)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 58.01599884 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 62.51599884 11.72200012 Tm [(HEL-S-51)-1(e)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 107.68699646 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 102 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P34)-1(89)-1(7)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 105 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 108 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(11)-1(91)-1(1)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 129 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 132 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 133 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 138 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 115.47499847 16.35000038 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 139 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 114.72499847 0.75 l 114.72499847 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 115.72499847 -0.25 l 115.72499847 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 151 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 152 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 115.47499847 0.75 m 426.17501831 0.75 l 426.17501831 109.94999695 l 115.47499847 109.94999695 l h f* Q q 1 0 0 1 115.09999847 0 cm -0.625 -0.25 m 312.07501221 -0.25 l 312.07501221 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 153 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 102.19599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 106.69599915 11.72200012 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(rial)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 166.8789978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 171.3789978 11.72200012 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 192.08999634 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 196.58999634 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 205.43200684 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 209.93200684 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 214.90699768 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 219.40699768 11.72200012 Tm [(pyrido)1(xal)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 259.16000366 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 263.66000366 11.72200012 Tm [(ph)1(osph)1(a)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(te-d)1(e)-1(p)1(e)-1(ndent)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 59.37900162 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 63.87900162 27.3220005 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 97.26000214 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 101.76000214 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 118.98200226 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 123.48200226 27.3220005 Tm [(cata)1(l)-1(yzes)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 162.15400696 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 166.65400696 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 180.65499878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 185.15499878 27.3220005 Tm [(reve)-1(r)1(sible)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 226.77600098 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 231.27600098 27.3220005 Tm [(reaction)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 266.32199097 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 270.82199097 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 279.66400146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 284.16400146 27.3220005 Tm [(seri)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ne)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 10.65200043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 15.15200043 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 31.42900085 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 35.92900085 42.92200089 Tm [(tetr)1(ahydro)1(folat)1(e)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 106.04399872 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 110.54399872 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 119.6190033 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 124.1190033 42.92200089 Tm [(glyc)-1(ine)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 154.59500122 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 159.09500122 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 175.37199402 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 179.87199402 42.92200089 Tm [(5,1)-1(0-meth)1(y)-1(lene)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 247.11700439 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 251.61700439 42.92200089 Tm [(tetr)1(ahydro)1(f)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(olat)1(e)-1(.)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 23.71699905 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 28.21699905 58.52199936 Tm [(The)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 44.02399826 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 48.52399826 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 86.03099823 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 90.53099823 58.52199936 Tm [(pro)1(duc)-1(t)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 124.60600281 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 129.10600281 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 135.66700745 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 140.16700745 58.52199936 Tm [(prima)1(rily)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 178.14500427 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 182.64500427 58.52199936 Tm [(responsib)1(l)-1(e)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 232.17999268 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 236.67999268 58.52199936 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 248.95799255 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 253.45799255 58.52199936 Tm [(glyc)-1(ine)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 283.93399048 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 288.43399048 58.52199936 Tm [(syn)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(th)1(e)-1(sis.)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 26.89500046 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 31.39500046 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 47.20199966 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 51.70199966 74.12200165 Tm [(activit)1(y)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 82.1740036 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 86.6740036 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 95.51599884 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 100.01599884 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 114.01699829 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 118.51699829 74.12200165 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 156.02400208 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 160.52400208 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 191.83099365 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 196.33099365 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 211.01300049 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 215.51300049 74.12200165 Tm [(been)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 237.02000427 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 241.52000427 74.12200165 Tm [(sugg)1(e)-1(st)1(e)-1(d)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 286.23400879 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 290.73400879 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 299.80899048 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(be)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 10.85400009 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 15.35400009 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 29.35499954 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 33.85499954 89.72200012 Tm [(prima)1(ry)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 67.04299927 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 71.54299927 89.72200012 Tm [(source)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 100.03299713 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 104.53299713 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 113.375 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 117.875 89.72200012 Tm [(intra)1(c)-1(ell)-1(ular)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 168.34199524 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 172.84199524 89.72200012 Tm [(glyc)-1(ine.)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 205.48500061 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 209.98500061 89.72200012 Tm [(The)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 225.79200745 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 230.29200745 89.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 251.80799866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 256.30801392 89.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 281.40499878 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 285.90499878 89.72200012 Tm [(en)-1(c)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(od)1(e)-1(s)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 20.75099945 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 25.25099945 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 39.2519989 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 43.7519989 105.3219986 Tm [(cy)-1(t)1(osolic)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 81.29399872 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 85.79399872 105.3219986 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 106.50499725 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 111.00499725 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 119.84700012 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 124.34700012 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 139.80299377 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 144.30299377 105.3219986 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 177.68400574 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 182.18400574 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 188.74499512 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 193.24499512 105.3219986 Tm [(located)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 225.06599426 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 229.56599426 105.3219986 Tm [(on)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 240.83399963 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 245.33399963 105.3219986 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 302.1289978 105.3219986 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 0.75 m 115.09999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 17.10000038 m 115.09999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 33.45000076 m 115.09999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 49.80000305 m 115.09999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 66.15000153 m 115.09999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 82.5 m 115.09999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 98.84999847 m 115.09999847 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 115.09999847 115.19999695 m 115.09999847 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17501831 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17501831 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17501831 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17501831 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17501831 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17501831 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17501831 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.7749939 m 426.92501831 224.7749939 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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