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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 84.2460022 23.67700005 Tm 0 g [(RGS22)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 143.3500061 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 154.3500061 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 331.0539856 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(RGS22)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 90.79299927 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 96.04299927 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 180.04299927 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(RGS22)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 90.79299927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 93.16699982 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 126.3690033 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 128.74299622 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 188.7230072 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 191.09700012 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 225.57099915 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(re)1(gul)-1(ator)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 102.4980011 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 104.87200165 12.82499981 Tm [(of)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 113.61299896 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 115.98699951 12.82499981 Tm [(G-protein)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 157.20799255 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 159.58200073 12.82499981 Tm [(si)-1(g)1(n)-1(ali)-1(ng)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 196.86500549 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 199.23899841 12.82499981 Tm [(22;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 212.69200134 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 215.06599426 12.82499981 Tm [(CT)-1(1)1(45;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 244.55599976 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 246.92999268 12.82499981 Tm [(PRTD-NY2)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 290.06298828 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 242.43400574 cm /P <</MCID 53 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 270.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 54 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(131-3)1(78)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(RGS22)] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAABB 9 Tf 1 0 0 -1 339.6289978 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 299.31201172 cm /P <</MCID 82 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 327.25100708 cm /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 355.19000244 cm /P <</MCID 85 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 383.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 90 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(regulat)1(or)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 39.72700119 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 44.22700119 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 53.06900024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 57.56900024 11.72200012 Tm [(G-)1(prot)1(ei)-1(n)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 99.46199799 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 103.96199799 11.72200012 Tm [(signaling)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 142.89300537 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 147.39300537 11.72200012 Tm [(22)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 157.94900513 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 100 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 101 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 102 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CT1)-1(45;)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 29.18000031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 33.68000031 11.72200012 Tm [(PRTD-)1(NY2)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 78.9960022 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 106 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 107 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 108 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q8NE0)-1(9)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 35.43299866 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 110 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 113 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 114 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(47)-1(06)-1(0)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 116 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 117 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 118 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 134 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 137 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 138 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 142 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 143 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 133.0249939 16.35000038 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 144 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 132.2749939 0.75 l 132.2749939 109.94999695 l 0.375 109.94999695 l h f* Q q -0.625 -0.25 m 133.2749939 -0.25 l 133.2749939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 58.52199936 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 157 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 133.0249939 0.75 m 426.17498779 0.75 l 426.17498779 109.94999695 l 133.0249939 109.94999695 l h f* Q q 1 0 0 1 132.6499939 0 cm -0.625 -0.25 m 294.5249939 -0.25 l 294.5249939 110.94999695 l -0.625 110.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 158 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(RG)1(S)-1(22)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 28.31800079 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 32.81800079 11.72200012 Tm [(\(regulat)1(or)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 75.55000305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 80.05000305 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 88.89199829 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 93.39199829 11.72200012 Tm [(G-)1(prot)1(ei)-1(n)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 135.28500366 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 139.78500366 11.72200012 Tm [(signaling)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 178.71600342 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 183.21600342 11.72200012 Tm [(22)-1(\),)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 198.94400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 203.44400024 11.72200012 Tm [(also)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 220.70100403 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 225.20100403 11.72200012 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 254.02000427 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 258.51998901 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 267.66101074 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 272.16101074 11.72200012 Tm [(FLJ)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(75)-1(00)-1(4,)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 28.55599976 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 33.05599976 27.3220005 Tm [(PRTD-)1(NY2,)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 80.53900146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 85.03900146 27.3220005 Tm [(FLJ4)-1(00)-1(80)-1(,)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 126.55899811 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 131.05900574 27.3220005 Tm [(MGC10)-1(290)-1(8)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 184.23300171 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 188.73300171 27.3220005 Tm [(or)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 197.89100647 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 202.39100647 27.3220005 Tm [(DK)1(F)-1(Zp434)-1(I09)-1(2,)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 267.54901123 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 272.04901123 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 278.60998535 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 4.9749999 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 9.47500038 42.92200089 Tm [(novel)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 32.9679985 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 37.4679985 42.92200089 Tm [(12)-1(64)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 58.57899857 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 63.07899857 42.92200089 Tm [(amino)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 90.14900208 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 94.64900208 42.92200089 Tm [(acid)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 112.28900146 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 116.78900146 42.92200089 Tm [(regulat)1(or)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 156.51600647 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 161.01600647 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 169.85800171 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 174.35800171 42.92200089 Tm [(G-)1(prot)1(ei)-1(n)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 216.25100708 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 220.75100708 42.92200089 Tm [(signaling)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 259.68200684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 264.18200684 42.92200089 Tm [(speci)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(fic)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 10.02799988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 14.52799988 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 23.60300064 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 28.10300064 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 37.1780014 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 41.6780014 58.52199936 Tm [(test)1(i)-1(s)1(.)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 66.38400269 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 70.88400269 58.52199936 Tm [(RG)1(S)-1(22)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 99.20200348 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 103.70200348 58.52199936 Tm [(inhibits)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 135.24200439 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 139.74200439 58.52199936 Tm [(signal)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 164.9750061 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 169.4750061 58.52199936 Tm [(tr)1(ansduc)-1(t)1(ion)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 223.78300476 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 228.28300476 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 244.55999756 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 249.05999756 58.52199936 Tm [(contains)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 285.2749939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 16.18099976 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 20.68099976 74.12200165 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 57.8409996 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 62.3409996 74.12200165 Tm [(as)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 71.48200226 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 75.98200226 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 80.95700073 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 85.45700073 74.12200165 Tm [(result)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 109.45999908 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 113.95999908 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 122.80200195 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 127.30200195 74.12200165 Tm [(alt)1(e)-1(rnat)1(ive)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 172.66700745 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 177.16700745 74.12200165 Tm [(splicin)-1(g)1(.)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 212.24899292 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 216.74899292 74.12200165 Tm [(RG)1(S)-1(22)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 245.06700134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 249.56700134 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 256.12799072 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 260.62799072 74.12200165 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 286.31799316 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 7.94099998 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 12.44099998 89.72200012 Tm [(spermat)1(og)1(e)-1(nic)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 76.69799805 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 81.19799805 89.72200012 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 99.77400208 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 104.27400208 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 120.5510025 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 125.0510025 89.72200012 Tm [(Le)-1(ydig)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 153.44799805 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 157.94799805 89.72200012 Tm [(ce)-1(lls,)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 178.69000244 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 183.19000244 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 199.46699524 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 203.96699524 89.72200012 Tm [(may)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 222.13800049 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 226.63800049 89.72200012 Tm [(be)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 237.49200439 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 241.99200439 89.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 278.36099243 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 282.86099243 89.72200012 Tm [(i)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(n)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 5.546 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 10.04599953 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 24.04700089 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 28.54700089 105.3219986 Tm [(tr)1(ansloc)-1(a)1(tion)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 84.64299774 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 89.14299774 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 97.98500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 102.48500061 105.3219986 Tm [(GNA)1(1)-1(3)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 133.38299561 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 137.88299561 105.3219986 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 158.59399414 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 163.09399414 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 177.09500122 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 181.59500122 105.3219986 Tm [(cy)-1(t)1(oplas)1(m)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 225.66299438 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 230.16299438 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 239.23800659 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 243.73800659 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 257.73901367 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 262.23901367 105.3219986 Tm [(nuc)-1(le)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 132.6499939 0.75 m 132.6499939 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 132.6499939 17.10000038 m 132.6499939 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 132.6499939 33.45000076 m 132.6499939 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 132.6499939 49.80000305 m 132.6499939 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w 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