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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 82.58100128 23.67700005 Tm 0 g [(RDH11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.01499939 23.67700005 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 156.01499939 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 332.71899414 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(RDH11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.34700012 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 97.59700012 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 181.59700012 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(RDH11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.34700012 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.72100067 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.92299652 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.29699707 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.2769928 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.65100098 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.125 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(re)1(ti)-1(nol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.27500153 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.06800079 12.82499981 Tm [(dehydrogenase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.83700562 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.63000488 12.82499981 Tm [(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.27400208 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.06700134 12.82499981 Tm [(\(al)-1(l-trans/)-1(9-cis/11-ci)-1(s\);)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.55599976 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.34899902 12.82499981 Tm [(MDT)-1(1)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.03399658 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 316.82699585 12.82499981 Tm [(CGI82;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 345.14801025 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 349.94100952 12.82499981 Tm [(PSDR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 380.48199463 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 385.2749939 12.82499981 Tm [(RALR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29800415 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(SC)-1(A)1(L)-1(D;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.18199921 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.55599976 30.49699783 Tm [(ARSDR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.44999695 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.8239975 30.49699783 Tm [(HCBP12)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.5530014 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.92700195 30.49699783 Tm [(SD)-1(R7C1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.15499878 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 21.08399963 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 260.37298584 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 288.31201172 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.30999756 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.34500122 12.04500008 Tm [(ter)1(min)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.33500671 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.36999512 12.04500008 Tm [(252)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.05499268 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.08999634 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.1309967 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.16600037 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.59700012 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.63200378 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.125 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.16000366 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.84599304 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.88101196 12.04500008 Tm [(RDH11)] TJ ET EMC /P <> BDC BT /FAAABB 9 Tf 1 0 0 -1 283.03500366 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 317.25100708 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 373.1289978 cm /P <> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 401.06799316 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(retinol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.95400047 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.45399857 11.72200012 Tm [(dehydro)1(gen)-1(a)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.69400024 11.72200012 Tm [(11)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.25 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.75 11.72200012 Tm [(\(all-t)1(rans/9-c)-1(is/11)-1(-)1(c)-1(is\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.35499573 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(MDT1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.25200081 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.7519989 11.72200012 Tm [(CGI82;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.83300018 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.33300018 11.72200012 Tm [(PSDR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.20899963 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.70899963 11.72200012 Tm [(RA)1(L)-1(R)1(1)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.85499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.35499573 11.72200012 Tm [(SCALD;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.54299927 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.04299927 11.72200012 Tm [(AR)1(S)-1(D)1(R1)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.1210022 11.72200012 Tm [(HCB)-1(P12;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.97799683 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.47799683 11.72200012 Tm [(SDR7C1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.97900391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q8T)-1(C12)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.34799957 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(11)-1(72)-1(7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 129.2749939 16.35000038 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 128.5249939 0.75 l 128.5249939 47.54999924 l 0.375 47.54999924 l h f* Q q -0.625 -0.25 m 129.5249939 -0.25 l 129.5249939 48.54999924 l -0.625 48.54999924 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 27.3220005 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 129.2749939 0.75 m 426.17498779 0.75 l 426.17498779 47.54999924 l 129.2749939 47.54999924 l h f* Q q 1 0 0 1 128.8999939 0 cm -0.625 -0.25 m 298.2749939 -0.25 l 298.2749939 48.54999924 l -0.625 48.54999924 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.68699646 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.18699646 11.72200012 Tm [(NAD)1(PH)-1(-)1(depende)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.07901001 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.57901001 11.72200012 Tm [(reti)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.91600037 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.41600037 27.3220005 Tm [(reduc)-1(t)1(ase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.375 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.875 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.15200043 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.65200043 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.6269989 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.1269989 27.3220005 Tm [(sho)1(rt-)1(c)-1(ha)1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.21000671 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.71000671 27.3220005 Tm [(dehydro)1(gen)-1(a)1(se)-1(/reductas)1(e)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.42001343 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.92001343 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.72698975 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.50699997 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.00699997 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.31400299 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.81400299 42.92200089 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.4960022 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.9960022 42.92200089 Tm [(no)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.26399994 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.76399994 42.92200089 Tm [(st)1(e)-1(ro)1(i)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.69999695 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.19999695 42.92200089 Tm [(dehydro)1(gen)-1(a)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.94000244 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.44000244 42.92200089 Tm [(activit)1(y)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.07800293 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 162 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 0.75 m 128.8999939 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 17.10000038 m 128.8999939 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 33.45000076 m 128.8999939 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 49.80000305 m 128.8999939 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 66.15000153 m 128.8999939 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 82.5 m 128.8999939 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 98.84999847 m 128.8999939 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 128.8999939 115.19999695 m 128.8999939 162 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 162 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 162.375 m 426.92498779 162.375 l S Q Q q 1 0 0 1 0 563.81799316 cm Q Q 1 0 0 -1 0 841.90002441 cm
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