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0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(ZF)-1(YVE)-1(1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 131.01400757 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 183.51400757 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 188.76400757 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(ZFY)-1(VE1)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 114.9980011 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 117.37200165 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 146.14399719 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 148.51800537 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 198.83900452 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 201.21299744 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 239.00900269 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(zi)-1(nc)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 79.51399994 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 81.88800049 12.82499981 Tm [(fi)-1(nge)1(r)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 106.84600067 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 109.22000122 12.82499981 Tm [(FY)-1(VE-)-1(ty)1(p)-1(e)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 152.47099304 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 154.84500122 12.82499981 Tm [(con)-1(taini)-1(ng)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 199.67999268 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 202.05400085 12.82499981 Tm [(1;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 210.18499756 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 212.55900574 12.82499981 Tm [(SR3;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 231.21600342 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 233.58999634 12.82499981 Tm [(DF)-1(CP1)1(;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 264.0289917 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 266.40301514 12.82499981 Tm [(TAFF)-1(1;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 295.375 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 297.74899292 12.82499981 Tm [(ZNFN2A)1(1;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 340.57400513 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 342.94799805 12.82499981 Tm [(PP)1(P1R1)1(72)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 386.20901489 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ZF)-1(YVE)-1(1)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 94.26399994 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0023>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 90 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 50.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 94.34999847 l 140.17500305 94.34999847 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(The)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(FYVE)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 41.55500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 46.05500031 11.72200012 Tm [(do)1(main)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 78.88200378 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 83.38200378 11.72200012 Tm [(mediat)1(e)-1(s)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 122.6740036 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 127.1740036 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 141.17500305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 145.67500305 11.72200012 Tm [(rec)-1(ruit)1(me)-1(nt)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 195.8999939 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 200.3999939 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 209.24200439 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 213.74200439 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 249.21499634 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 253.71499634 11.72200012 Tm [(invol)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ved)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 15.58699989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 20.08699989 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 28.02799988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 32.52799988 27.3220005 Tm [(membrane)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 79.31199646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 83.81199646 27.3220005 Tm [(tr)1(aff)1(i)-1(cki)-1(ng)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 127.3219986 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 131.82200623 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 148.09899902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 152.59899902 27.3220005 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 167.00900269 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 171.50900269 27.3220005 Tm [(signaling)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 210.44000244 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 214.94000244 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 224.01499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 228.51499939 27.3220005 Tm [(ph)1(osph)1(ati)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(dylinosito)1(l)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 44.60900116 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 49.10900116 42.92200089 Tm [(3-ph)1(osph)1(ate-conta)1(i)-1(ning)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 153.82200623 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 158.32200623 42.92200089 Tm [(membranes.)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 211.43899536 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 215.93899536 42.92200089 Tm [(This)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 233.20100403 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 237.70100403 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 269.00799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(contains)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 36.21500015 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 40.71500015 58.52199936 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 56.89599991 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 61.39599991 58.52199936 Tm [(zinc-binding)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 115.31300354 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 119.81300354 58.52199936 Tm [(FYVE)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 141.06100464 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 145.56100464 58.52199936 Tm [(do)1(mains)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 182.55400085 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 187.05400085 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 194.99499512 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 199.49499512 58.52199936 Tm [(ta)1(n)-1(d)1(e)-1(m)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 232.66499329 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 237.16499329 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 253.44200134 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 257.94198608 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 264.50299072 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 269.00299072 58.52199936 Tm [(r)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(eport)1(e)-1(d)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 34.22900009 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 38.72900009 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 47.80400085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 52.30400085 74.12200165 Tm [(localize)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 84.23000336 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 88.73000336 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 97.80500031 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 102.30500031 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 116.30599976 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 120.80599976 74.12200165 Tm [(Go)1(l)-1(g)1(i)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 143.76699829 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 148.26699829 74.12200165 Tm [(ap)1(para)1(tus.)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 193.35499573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 197.85499573 74.12200165 Tm [(Alt)1(e)-1(rna)1(tive)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 244.57800293 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 249.07800293 74.12200165 Tm [(splici)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ng)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 11.30300045 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 15.80300045 89.72200012 Tm [(results)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 43.97200012 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 48.47200012 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 56.4129982 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 60.9129982 89.72200012 Tm [(multiple)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 96.28500366 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 100.78500366 89.72200012 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 141.70700073 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 146.20700073 89.72200012 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 181.94299316 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 94.34999847 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 187 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 188 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 189 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 110.69999695 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 191 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 196 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 197 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(ZFYVE1)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 127.05000305 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 199 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 200 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 201 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(ZFYVE1)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 148.45199585 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 143.3999939 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 211 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 214 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 215 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(zinc)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 16.87899971 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 21.37899971 11.72200012 Tm [(finger)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 46.74000168 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 51.24000168 11.72200012 Tm [(FYVE-)1(type)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 95.35199738 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 99.85199738 11.72200012 Tm [(containing)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 145.59899902 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 150.09899902 11.72200012 Tm [(1)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 155.3769989 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 159.75 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 225 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 226 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 227 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(SR3;)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 18.51399994 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 23.01399994 11.72200012 Tm [(DFCP1;)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 53.62200165 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 58.12200165 11.72200012 Tm [(TAFF1)-1(;)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 86.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 91.1210022 11.72200012 Tm [(ZNFN2)-1(A)1(1)-1(;)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 135.17199707 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 139.67199707 11.72200012 Tm [(PPP)1(1)-1(R17)-1(2)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 183.17799377 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 176.1000061 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 237 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Sw)1(iss)1(P)-1(r)1(o)-1(t:)] TJ ET EMC /P <</MCID 238 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.56900024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 239 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Q9H)-1(BF4)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 35.27899933 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 192.44999695 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 241 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 15.8380003 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 20.33799934 11.72200012 Tm [(Predic)1(ted)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 63.54499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 68.04499817 11.72200012 Tm [(band)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 91.05000305 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 95.55000305 11.72200012 Tm [(siz)1(e:)] TJ ET EMC /P <</MCID 248 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 115.08799744 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 249 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(87)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 10.55599976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 15.05599976 11.72200012 Tm [(KD)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 27.62400055 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 0.75 m 139.80000305 94.34999847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 95.09999847 m 139.80000305 110.69999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 111.44999695 m 139.80000305 127.04999542 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 127.79999542 m 139.80000305 143.3999939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 144.1499939 m 139.80000305 159.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 160.5 m 139.80000305 176.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 176.8500061 m 139.80000305 192.45001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 193.20001221 m 139.80000305 208.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 208.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 94.72499847 m 422.42498779 94.72499847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 111.07499695 m 422.42498779 111.07499695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 127.42499542 m 422.42498779 127.42499542 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 143.7749939 m 422.42498779 143.7749939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 160.125 m 422.42498779 160.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 176.4750061 m 422.42498779 176.4750061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 192.82501221 m 422.42498779 192.82501221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17501831 m 423.17498779 209.17501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 114 0 R/Length 30036>>stream
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