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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 78.89600372 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 150.66000366 23.67700005 Tm 0 Tr [(WNT3A)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 225.96299744 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 336.40301514 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(WN)1(T3A)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 132.38299561 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 184.88299561 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.38299561 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(W)1(NT3A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.36599731 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.73999786 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.51199341 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.88600159 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.20700073 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.58099365 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.3769989 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Wnt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.375 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.74900055 12.82499981 Tm [(famil)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.94300079 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.31700134 12.82499981 Tm [(me)1(mb)-1(e)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.71800232 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.09199524 12.82499981 Tm [(3A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(WN)1(T3A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.63300323 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q /GS2 gs 1 g 0.375 0.75 m 138.67500305 0.75 l 138.67500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 139.67500305 -0.25 l 139.67500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.42500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 139.42500305 156.75 l h f* Q q 1 0 0 1 139.05000305 0 cm -0.625 -0.25 m 284.375 -0.25 l 284.375 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(WNT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.94100189 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.44100189 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.95700073 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.45700073 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.53900146 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.03900146 11.72200012 Tm [(consists)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.06599426 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.56599426 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.40800476 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.90800476 11.72200012 Tm [(st)1(ruc)-1(tura)1(ll)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.78599548 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.28599548 11.72200012 Tm [(related)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.41499329 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.91499329 11.72200012 Tm [(gene)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.59698486 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.09700012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.59700012 27.3220005 Tm [(en)-1(cod)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.34700012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.84700012 27.3220005 Tm [(sec)-1(reted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.39199829 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.89199829 27.3220005 Tm [(signaling)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.82299805 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.32299805 27.3220005 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.96200562 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.46200562 27.3220005 Tm [(These)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.54200745 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.04200745 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.51501465 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.01501465 27.3220005 Tm [(ha)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.83100033 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.33100033 42.92200089 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.83800125 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.33800125 42.92200089 Tm [(implicated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.40799713 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.90799713 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.84899902 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.34899902 42.92200089 Tm [(oncogene)-1(sis)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.09399414 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.59399414 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.8710022 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.3710022 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.31199646 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.81199646 42.92200089 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.72099304 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.22099304 42.92200089 Tm [(developm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(en)-1(t)1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.375 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.875 58.52199936 Tm [(pro)1(c)-1(esses,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.17199707 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.67199707 58.52199936 Tm [(inc)-1(luding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52200317 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.02200317 58.52199936 Tm [(regulat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.25300598 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.75300598 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.59500122 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.09500122 58.52199936 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.50500488 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.00500488 58.52199936 Tm [(fa)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.55900574 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.05900574 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.33599854 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.83599854 58.52199936 Tm [(pa)1(tterni)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.30300045 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80300045 74.12200165 Tm [(during)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.24000168 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.74000168 74.12200165 Tm [(embryogene)-1(s)1(i)-1(s)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.35900116 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.85900116 74.12200165 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.1210022 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.6210022 74.12200165 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.13699341 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.63699341 74.12200165 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.19799805 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.69799805 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.67300415 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.17300415 74.12200165 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.43699646 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.93699646 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.77900696 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.27900696 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.27999878 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.77999878 74.12200165 Tm [(W)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(NT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.47599983 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.97599983 89.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.49200058 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.99200058 89.72200012 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.23999786 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.73999786 89.72200012 Tm [(It)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.73899841 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.23899841 89.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.15599823 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.65599823 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.6309967 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.1309967 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.43800354 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.93800354 89.72200012 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.03500366 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.53500366 89.72200012 Tm [(sho)1(ws)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.23599243 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.73599243 89.72200012 Tm [(96)-1(%)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.29800415 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.79800415 89.72200012 Tm [(ami)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(no)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.26799965 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.76799965 105.3219986 Tm [(acid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.40800095 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.90800095 105.3219986 Tm [(identity)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.57700348 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.07700348 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.15200043 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.65200043 105.3219986 Tm [(mouse)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.625 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.125 105.3219986 Tm [(Wnt)1(3)-1(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.79200745 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.29200745 105.3219986 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.76499939 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.26499939 105.3219986 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.54200745 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.04200745 105.3219986 Tm [(84)-1(%)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.60400391 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.10400391 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.17900085 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.67900085 105.3219986 Tm [(huma)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.546 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04599953 120.92199707 Tm [(WNT3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.95800018 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.45800018 120.92199707 Tm [(pro)1(tein)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.93099976 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.43099976 120.92199707 Tm [(anot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.11100006 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.61100006 120.92199707 Tm [(WNT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.24499512 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.74499512 120.92199707 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.26100159 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.76100159 120.92199707 Tm [(pro)1(duc)-1(t)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.00300598 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.50300598 120.92199707 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.76499939 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.26499939 120.92199707 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.78100586 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.28100586 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.8420105 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.3420105 120.92199707 Tm [(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(lustered)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.86600113 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.36600113 136.52200317 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.76200104 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.26200104 136.52200317 Tm [(WNT14)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.45200348 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.95200348 136.52200317 Tm [(gene)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.63400269 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.13400269 136.52200317 Tm [(anot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.81399536 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.31399536 136.52200317 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.39599609 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.89599609 136.52200317 Tm [(member,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.32600403 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.82600403 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.76699829 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.26699829 136.52200317 Tm [(chro)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(moso)1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.58200073 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.08200073 152.12199402 Tm [(1q4)-1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.67200089 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.17199707 152.12199402 Tm [(region.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.3010025 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 138.67500305 0.75 l 138.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 139.67500305 -0.25 l 139.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 139.42500305 16.35000038 l h f* Q q 1 0 0 1 139.05000305 0 cm -0.625 -0.25 m 284.375 -0.25 l 284.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.1000061 cm q /GS2 gs 1 g 0.375 0.75 m 138.67500305 0.75 l 138.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 139.67500305 -0.25 l 139.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 139.42500305 16.35000038 l h f* Q q 1 0 0 1 139.05000305 0 cm -0.625 -0.25 m 284.375 -0.25 l 284.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WNT3A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.24499893 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 189.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 138.67500305 0.75 l 138.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 139.67500305 -0.25 l 139.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 139.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 139.42500305 16.35000038 l h f* Q q 1 0 0 1 139.05000305 0 cm -0.625 -0.25 m 284.375 -0.25 l 284.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(WNT3A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.59100342 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 205.80001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.05000305 0.75 m 139.05000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.05000305 157.5 m 139.05000305 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.05000305 173.8500061 m 139.05000305 189.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.05000305 190.20001221 m 139.05000305 205.80001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 205.80001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 173.4750061 m 422.42498779 173.4750061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 189.82501221 m 422.42498779 189.82501221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 206.17501831 m 423.17498779 206.17501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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