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g [<000E000B000C000D>] TJ ET EMC /P <</MCID 15 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(W)1(DR74)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 115.8789978 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 118.25299835 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 147.0249939 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 149.39900208 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 199.72000122 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 202.09399414 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 239.88999939 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P 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g [<0005>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0010>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(WDR74)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 74.14600372 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0012>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 73.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 87.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 113.60800171 12.82499981 Tm [<00180019>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001A>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<001B>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 71.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 101.36000061 12.82499981 Tm [(Do)-1(g)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 118.2990036 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 120.67299652 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 123.29299927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 125.66699982 12.82499981 Tm [(Rat)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 139.91499329 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 142.28900146 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 144.90899658 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 147.28300476 12.82499981 Tm [(Mon)-1(k)1(ey)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 182.06399536 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 184.43800354 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 187.05799866 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 189.43200684 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 218.79400635 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002000210022000F>] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230005>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 94 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0024>] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 96 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0025>] TJ ET EMC /P <</MCID 97 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 98 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0026>] TJ ET EMC /P <</MCID 99 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 105 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800220027>] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 113 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 114 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 115 >> BDC BT /FAAACJ 18 Tf 1 0 0 -1 42 20.17499924 Tm 1 Tr 0.51428574 w /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 140.17500305 0.75 l 140.17500305 203.55000305 l 0.375 203.55000305 l h f* Q q -0.625 -0.25 m 141.17500305 -0.25 l 141.17500305 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 116 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 105.3219986 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 117 >> BDC BT /FAAADF 9 Tf 1 0 0 -1 57.29199982 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.92500305 0.75 m 422.42498779 0.75 l 422.42498779 203.55000305 l 140.92500305 203.55000305 l h f* Q q 1 0 0 1 140.55000305 0 cm 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[(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 171.43499756 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 175.93499756 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 183.87600708 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 188.37600708 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 193.35099792 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 197.85099792 11.72200012 Tm [(var)1(i)-1(ety)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 226.60400391 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 231.10400391 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 239.94599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 244.44599915 11.72200012 Tm [(pro)1(tei)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ns)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 9.71199989 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 14.21199989 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 30.48900032 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 34.98899841 27.3220005 Tm [(are)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 48.50699997 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 53.00699997 27.3220005 Tm [(chara)1(c)-1(terized)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 110.54000092 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 115.04000092 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 125.55200195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 130.05200195 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 135.0269928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 139.5269928 27.3220005 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 183.60400391 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 188.10400391 27.3220005 Tm [(core)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 206.88200378 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 211.38200378 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 220.22399902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 224.72399902 27.3220005 Tm [(40)-1(-)1(6)-1(0)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 249.72900391 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 254.22900391 27.3220005 Tm [(ami)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(no)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 11.26799965 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 15.76799965 42.92200089 Tm [(acids)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 37.57400131 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 42.07400131 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 59.29600143 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 63.79600143 42.92200089 Tm [(commonly)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 109.32299805 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 113.82299805 42.92200089 Tm [(fo)1(rm)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 134.53399658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 139.03399658 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 144.00900269 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 148.50900269 42.92200089 Tm [(tert)1(iary)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 179.32800293 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 183.82800293 42.92200089 Tm [(pro)1(pell)-1(er)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 222.92199707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 227.42199707 42.92200089 Tm [(st)1(ruc)-1(ture.)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 268.04501343 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(Wh)1(il)-1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 24.59600067 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 29.09600067 58.52199936 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 64.56900024 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 69.06900024 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 86.29100037 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 90.79100037 58.52199936 Tm [(contain)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 122.83999634 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 127.33999634 58.52199936 Tm [(WD)1(-repeat)1(s)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 179.13800049 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 183.63800049 58.52199936 Tm [(pa)1(rticipat)1(e)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 229.63600159 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 234.13600159 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 242.07699585 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 246.57699585 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 251.55200195 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 256.05200195 58.52199936 Tm [(wid)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(e)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 5.10599995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 9.60599995 74.12200165 Tm [(rang)1(e)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 34.42599869 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 38.92599869 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 47.76800156 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 52.26800156 74.12200165 Tm [(ce)-1(llular)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 83.02999878 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 87.52999878 74.12200165 Tm [(func)-1(t)1(ions,)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 129.60299683 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 134.10299683 74.12200165 Tm [(th)1(e)-1(y)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 152.86799622 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 157.36799622 74.12200165 Tm [(are)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 170.88600159 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 175.38600159 74.12200165 Tm [(gene)-1(r)1(ally)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 214.86599731 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 219.36599731 74.12200165 Tm [(involved)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 255.73500061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 260.23498535 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 268.17599487 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(regulat)1(ory)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 44.49000168 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 48.99000168 89.72200012 Tm [(mec)-1(ha)1(n)-1(isms)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 102.26499939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 106.76499939 89.72200012 Tm [(conc)-1(ernin)-1(g)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 154.84599304 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 159.34599304 89.72200012 Tm [(chromat)1(in)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 203.26100159 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 207.76100159 89.72200012 Tm [(assembly,)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 249.67999268 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 254.17999268 89.72200012 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 268.58999634 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(cy)-1(cle)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 21.29199982 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 25.79199982 105.3219986 Tm [(control,)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 58.64599991 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 63.14599991 105.3219986 Tm [(signal)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 88.3789978 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 92.8789978 105.3219986 Tm [(tr)1(ansduc)-1(t)1(ion,)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 149.35299683 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 153.85299683 105.3219986 Tm [(RNA)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 173.37800598 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 177.87800598 105.3219986 Tm [(pro)1(c)-1(essing,)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 226.6000061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 231.1000061 105.3219986 Tm [(ap)1(opt)1(osis)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 273.09399414 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 16.27700043 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 20.77700043 120.92199707 Tm [(vesic)-1(ular)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 58.0340004 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 62.5340004 120.92199707 Tm [(tr)1(aff)1(i)-1(cki)-1(ng)1(.)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 108.21099854 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 112.71099854 120.92199707 Tm [(WD)1(R7)-1(4)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 145.15600586 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 149.65600586 120.92199707 Tm [(\(WD)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 168.67599487 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 173.17599487 120.92199707 Tm [(repeat)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 200.90100098 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 205.40100098 120.92199707 Tm [(do)1(main)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 238.22799683 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 242.72799683 120.92199707 Tm [(74)-1(\),)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 258.45599365 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 262.95599365 120.92199707 Tm [(als)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(o)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 5.72200012 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 10.22200012 136.52200317 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 39.04100037 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 43.54100037 136.52200317 Tm [(as)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 52.68199921 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 57.18199921 136.52200317 Tm [(NOP)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 77.33999634 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 81.83999634 136.52200317 Tm [(seve)-1(n-)1(associated)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 155.50999451 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 160.00999451 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 191.31700134 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 195.81700134 136.52200317 Tm [(1)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 201.09500122 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 205.59500122 136.52200317 Tm [(\(NSA1\),)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 237.89500427 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 242.39500427 136.52200317 Tm [(is)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 248.95599365 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 253.45599365 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 258.43099976 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 262.93099976 136.52200317 Tm [(38)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(5)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 5.27799988 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 9.77799988 152.12199402 Tm [(amino)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 36.84799957 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 41.34799957 152.12199402 Tm [(acid)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 58.98799896 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 63.48799896 152.12199402 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 94.79499817 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 99.29499817 152.12199402 Tm [(th)1(at)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 116.51699829 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 121.01699829 152.12199402 Tm [(localizes)] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 157.10899353 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 161.60899353 152.12199402 Tm [(to)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 170.68400574 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 175.18400574 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 189.18499756 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 193.68499756 152.12199402 Tm [(nuc)-1(leolus)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 234.61999512 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 239.11999512 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 255.39700317 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 259.89700317 152.12199402 Tm [(co)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(ntains)] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 25.97999954 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 30.47999954 167.72200012 Tm [(six)] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 41.60300064 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 46.10300064 167.72200012 Tm [(WD)] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 62.11700058 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 66.61699677 167.72200012 Tm [(repeats)1(.)] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 100.67500305 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 105.17500305 167.72200012 Tm [(Exist)1(in)-1(g)] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 138.29699707 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 142.79699707 167.72200012 Tm [(as)] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 151.93800354 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 156.43800354 167.72200012 Tm [(tw)1(o)] TJ ET EMC /P <</MCID 313 >> BDC BT 1 0 0 -1 172.6190033 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 314 >> BDC BT 1 0 0 -1 177.1190033 167.72200012 Tm [(alt)1(e)-1(rnat)1(ive)-1(ly)] TJ ET EMC /P <</MCID 315 >> BDC BT 1 0 0 -1 229.64199829 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 316 >> BDC BT 1 0 0 -1 234.14199829 167.72200012 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 317 >> BDC BT 1 0 0 -1 264.22299194 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 318 >> BDC BT 1 0 0 -1 268.72299194 167.72200012 Tm [(i)] TJ ET EMC /P <</MCID 319 >> BDC BT 1 0 0 -1 0 183.32200623 Tm [(sof)1(orms,)] TJ ET EMC /P <</MCID 320 >> BDC BT 1 0 0 -1 36.93199921 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 321 >> BDC BT 1 0 0 -1 41.43199921 183.32200623 Tm [(th)1(e)] TJ ET EMC /P <</MCID 322 >> BDC BT 1 0 0 -1 55.43299866 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 323 >> BDC BT 1 0 0 -1 59.93299866 183.32200623 Tm [(gene)] TJ ET EMC /P <</MCID 324 >> BDC BT 1 0 0 -1 81.4489975 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 325 >> BDC BT 1 0 0 -1 85.9489975 183.32200623 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 326 >> BDC BT 1 0 0 -1 126.29100037 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 327 >> BDC BT 1 0 0 -1 130.79100037 183.32200623 Tm [(WD)1(R7)-1(4)] TJ ET EMC /P <</MCID 328 >> BDC BT 1 0 0 -1 163.23599243 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 329 >> BDC BT 1 0 0 -1 167.73599243 183.32200623 Tm [(map)1(s)] TJ ET EMC /P <</MCID 330 >> BDC BT 1 0 0 -1 191.05799866 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 331 >> BDC BT 1 0 0 -1 195.55799866 183.32200623 Tm [(to)] TJ ET EMC /P <</MCID 332 >> BDC BT 1 0 0 -1 204.63299561 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 333 >> BDC BT 1 0 0 -1 209.13299561 183.32200623 Tm [(human)] TJ ET EMC /P <</MCID 334 >> BDC BT 1 0 0 -1 239.17399597 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 335 >> BDC BT 1 0 0 -1 243.67399597 183.32200623 Tm [(chrom)] TJ ET EMC /P <</MCID 336 >> BDC BT 1 0 0 -1 0 198.92199707 Tm [(oso)1(me)] TJ ET EMC /P <</MCID 337 >> BDC BT 1 0 0 -1 29.14900017 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 338 >> BDC BT 1 0 0 -1 33.64899826 198.92199707 Tm [(11)-1(,)] TJ ET EMC /P <</MCID 339 >> BDC BT 1 0 0 -1 46.37099838 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 340 >> BDC BT 1 0 0 -1 50.87099838 198.92199707 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 341 >> BDC BT 1 0 0 -1 75.96800232 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 342 >> BDC BT 1 0 0 -1 80.46800232 198.92199707 Tm [(ho)1(u)-1(ses)] TJ ET EMC /P <</MCID 343 >> BDC BT 1 0 0 -1 110.71600342 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 344 >> BDC BT 1 0 0 -1 115.21600342 198.92199707 Tm [(over)] TJ ET EMC /P <</MCID 345 >> BDC BT 1 0 0 -1 134.20500183 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 346 >> BDC BT 1 0 0 -1 138.70500183 198.92199707 Tm [(1,4)-1(00)] TJ ET EMC /P <</MCID 347 >> BDC BT 1 0 0 -1 161.98300171 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 348 >> BDC BT 1 0 0 -1 166.48300171 198.92199707 Tm [(gene)-1(s)] TJ ET EMC /P <</MCID 349 >> BDC BT 1 0 0 -1 192.16499329 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 350 >> BDC BT 1 0 0 -1 196.66499329 198.92199707 Tm [(and)] TJ ET EMC /P <</MCID 351 >> BDC BT 1 0 0 -1 212.94200134 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 352 >> BDC BT 1 0 0 -1 217.44200134 198.92199707 Tm [(comprises)] TJ ET EMC /P <</MCID 353 >> BDC BT 1 0 0 -1 261.12799072 198.92199707 Tm [( )] TJ ET EMC /P <</MCID 354 >> BDC BT 1 0 0 -1 265.62799072 198.92199707 Tm [(n)] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 140.55000305 0.75 m 140.55000305 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 203.92500305 m 423.17498779 203.92500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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