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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 88 0 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 71.76399994 23.67700005 Tm 0 Tr [(VP)-1(S)1(50)] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 134.68099976 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 245.1210022 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(VPS50)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 116.09999847 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 168.6000061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 173.8500061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(VPS50)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 110.58300018 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 112.95700073 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 141.72900391 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 144.10299683 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 194.42399597 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 196.79800415 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 234.59399414 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(VPS50,)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 92.47000122 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 94.84400177 12.82499981 Tm [(EARP)1(/)-1(GA)1(RPII)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 150.34300232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 152.71699524 12.82499981 Tm [(compl)-1(e)1(x)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 188.77999878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 191.15400696 12.82499981 Tm [(su)-1(bun)-1(it;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 226.06300354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 228.43699646 12.82499981 Tm [(VPS54L)-1(;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 262.51098633 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 264.88500977 12.82499981 Tm [(CCD)-1(C132)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 304.10598755 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(VPS50)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 89.84999847 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002300240025000E>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 77 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 78 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 79 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 80 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 143.92500305 125.55000305 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 82 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Acts)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 18.36499977 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 22.86499977 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 32.00600052 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 36.50600052 11.72200012 Tm [(component)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 86.19499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 90.69499969 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 99.53700256 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 104.03700256 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 118.03800201 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 122.53800201 11.72200012 Tm [(EA)1(RP)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 145.20100403 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 149.70100403 11.72200012 Tm [(complex)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 186.17999268 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 190.67999268 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 207.9019928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 212.4019928 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 218.96299744 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 223.46299744 11.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 259.83200073 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 264.33200073 11.72200012 Tm [(i)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(n)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 5.546 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 10.04599953 27.3220005 Tm [(en)-1(d)1(ocy)-1(t)1(ic)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 51.71500015 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 56.21500015 27.3220005 Tm [(rec)-1(ycl)-1(ing.)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 96.80699921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 101.30699921 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 117.11399841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 121.61399841 27.3220005 Tm [(EA)1(RP)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 144.2769928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 148.7769928 27.3220005 Tm [(complex)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 185.2559967 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 189.7559967 27.3220005 Tm [(asso)1(c)-1(iat)1(e)-1(s)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 233.29299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 237.79299927 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 256.18899536 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 260.68899536 27.3220005 Tm [(Ra)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(b4-p)1(ositive)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 48.52899933 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 53.02899933 42.92200089 Tm [(en)-1(d)1(osomes)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 102.75299835 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 107.25299835 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 123.52999878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 128.02999878 42.92200089 Tm [(pro)1(motes)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 169.71699524 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 174.21699524 42.92200089 Tm [(rec)-1(ycl)-1(ing)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 212.64300537 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 217.14300537 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 225.98500061 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 230.48500061 42.92200089 Tm [(internaliz)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ed)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 10.86299992 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 15.36299992 58.52199936 Tm [(tr)1(ansferrin)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 59.88000107 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 64.37999725 58.52199936 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 100.80200195 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 105.30200195 58.52199936 Tm [(\(TFRC\))] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 133.1499939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 137.6499939 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 146.7250061 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 151.2250061 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 165.22599792 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 169.72599792 58.52199936 Tm [(plas)1(ma)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 200.41700745 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 204.91700745 58.52199936 Tm [(membrane.)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 253.86799622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 258.36801147 58.52199936 Tm [(Wi)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(th)1(in)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 16.83499908 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 21.33499908 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 35.33599854 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 39.83599854 74.12200165 Tm [(EA)1(RP)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 62.49900055 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 66.99900055 74.12200165 Tm [(complex,)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 105.64499664 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 110.14499664 74.12200165 Tm [(required)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 146.68600464 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 151.18600464 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 160.26100159 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 164.76100159 74.12200165 Tm [(teth)1(e)-1(r)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 190.65800476 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 195.15800476 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 209.15899658 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 213.65899658 74.12200165 Tm [(complex)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 250.13800049 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 254.63800049 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 263.7130127 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 268.2130127 74.12200165 Tm [(r)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ec)-1(yc)-1(ling)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 34.98899841 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 39.48899841 89.72200012 Tm [(en)-1(d)1(osomes.)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 91.37999725 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 95.87999725 89.72200012 Tm [(Not)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 112.27200317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 116.77200317 89.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 153.14100647 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 157.64100647 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 165.58200073 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 170.08200073 89.72200012 Tm [(retro)1(grad)1(e)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 216.16700745 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 220.66700745 89.72200012 Tm [(tr)1(anspor)1(t)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 260.40200806 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 264.90200806 89.72200012 Tm [(fr)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(om)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 14.15499973 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 18.65500069 105.3219986 Tm [(early)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 39.33100128 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 43.83100128 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 60.10800171 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 64.60800171 105.3219986 Tm [(lat)1(e)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 80.43699646 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 84.93699646 105.3219986 Tm [(en)-1(d)1(osomes)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 134.66099548 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 139.16099548 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 148.23599243 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 152.73599243 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 166.73699951 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 171.23699951 105.3219986 Tm [(tr)1(ans-G)1(olgi)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 219.56799316 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 224.06799316 105.3219986 Tm [(ne)-1(t)1(wo)1(rk)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 259.23699951 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 263.73699951 105.3219986 Tm [(\()] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(TGN\).)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 24.3409996 120.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 125.55000305 cm q 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 207 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 208 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 143.92500305 16.35000038 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 209 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 141.8999939 cm q 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 211 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 216 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 143.92500305 16.35000038 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 217 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(VPS5)-1(0)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 27.34300041 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 158.25 cm q 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 219 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 220 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 143.92500305 16.35000038 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 221 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(VPS5)-1(0)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 143.68899536 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 174.6000061 cm q 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 231 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 234 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 143.92500305 16.35000038 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 235 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(VPS5)-1(0,)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 29.50900078 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 34.00899887 11.72200012 Tm [(EA)1(RP/GAR)1(PII)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 90.21499634 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 94.71499634 11.72200012 Tm [(complex)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 131.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 135.69400024 11.72200012 Tm [(subunit)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 167.9940033 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 190.94999695 cm q 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 243 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 244 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 143.92500305 16.35000038 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 245 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(VPS5)-1(4L;)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 34.12799835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 38.62799835 11.72200012 Tm [(CCDC132)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 79.37799835 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 207.30003357 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 0.75 m 143.55000305 125.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 126.30000305 m 143.55000305 141.90000916 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 142.65000916 m 143.55000305 158.25001526 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 159.00001526 m 143.55000305 174.60002136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 175.35002136 m 143.55000305 190.95002747 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 191.70002747 m 143.55000305 207.30003357 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 207.30003357 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 125.92500305 m 422.42498779 125.92500305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 142.27500916 m 422.42498779 142.27500916 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 158.62501526 m 422.42498779 158.62501526 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 174.97502136 m 422.42498779 174.97502136 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 191.32502747 m 422.42498779 191.32502747 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 207.67503357 m 423.17498779 207.67503357 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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