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[<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(VIM)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 117.33000183 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 169.83000183 12.82499981 Tm [(   )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 185.58000183 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(VIM)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 101.31400299 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 103.68800354 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 132.46000671 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 134.83399963 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 185.15499878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 187.52900696 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 225.32499695 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Vi)-1(me)1(n)-1(tin;)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 104.74900055 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 107.1230011 12.82499981 Tm [(HEL)-1(11)1(3;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 141.98100281 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 144.35499573 12.82499981 Tm [(CT)-1(R)1(C)-1(T30)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 182.13000488 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 31 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 32 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(VIM)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 80.58000183 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 78 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q /GS2 gs 1 g 0.375 0.75 m 144.67500305 0.75 l 144.67500305 187.94999695 l 0.375 187.94999695 l h f* Q q -0.625 -0.25 m 145.67500305 -0.25 l 145.67500305 188.94999695 l -0.625 188.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 81 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 97.52200317 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 97.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 145.42500305 0.75 m 422.42498779 0.75 l 422.42498779 187.94999695 l 145.42500305 187.94999695 l h f* Q q 1 0 0 1 145.05000305 0 cm -0.625 -0.25 m 278.375 -0.25 l 278.375 188.94999695 l -0.625 188.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(intermediate)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 225.23899841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 229.73899841 11.72200012 Tm [(filament)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 265.06201172 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 28.24799919 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 32.7480011 27.3220005 Tm [(Intermediat)1(e)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 87.96099854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 92.46099854 27.3220005 Tm [(filamentents,)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 148.12199402 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 152.62199402 27.3220005 Tm [(along)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 177.01600647 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 181.51600647 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 199.91200256 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 204.41200256 27.3220005 Tm [(mic)-1(r)1(otubules)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 260.77200317 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 265.27200317 27.3220005 Tm [(a)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(nd)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 11.30300045 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 15.80300045 42.92200089 Tm [(actin)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 36.58499908 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 41.08499908 42.92200089 Tm [(mic)-1(r)1(ofilaments,)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 107.23999786 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 111.73999786 42.92200089 Tm [(make)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 135.15400696 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 139.65400696 42.92200089 Tm [(up)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 150.94799805 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 155.44799805 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 169.44900513 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 173.94900513 42.92200089 Tm [(cy)-1(t)1(oske)-1(leton.)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 230.76100159 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 235.26100159 42.92200089 Tm [(The)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 251.06799316 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 255.56799316 42.92200089 Tm [(pr)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ot)1(e)-1(in)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 22.12199974 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 26.62199974 58.52199936 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 64.1289978 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 68.6289978 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 79.14099884 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 83.64099884 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 99.09700012 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 103.59700012 58.52199936 Tm [(gene)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 125.11299896 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 129.61300659 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 136.17399597 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 140.67399597 58.52199936 Tm [(responsib)1(l)-1(e)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 190.20899963 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 194.70899963 58.52199936 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 206.98699951 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 211.48699951 58.52199936 Tm [(mainta)1(in)-1(ing)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 262.80200195 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 14.40999985 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 18.90999985 74.12200165 Tm [(sha)1(pe,)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 46.61299896 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 51.11299896 74.12200165 Tm [(integrit)1(y)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 87.21800232 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 91.71800232 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 100.55999756 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 105.05999756 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 119.06099701 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 123.56099701 74.12200165 Tm [(cy)-1(t)1(oplas)1(m,)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 169.79600525 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 174.29600525 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 190.57299805 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 195.07299805 74.12200165 Tm [(st)1(abilizing)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 238.6230011 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 243.1230011 74.12200165 Tm [(cy)-1(t)1(os)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ke)-1(letal)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 28.22999954 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 32.72999954 89.72200012 Tm [(interactions.)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 85.40299988 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 89.90299988 89.72200012 Tm [(It)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 95.90200043 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 100.40200043 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 106.96299744 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 111.46299744 89.72200012 Tm [(also)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 128.72000122 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 133.22000122 89.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 169.58900452 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 174.08900452 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 182.02999878 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 186.52999878 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 200.53100586 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 205.03100586 89.72200012 Tm [(immun)-1(e)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 240.49000549 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 244.99000549 89.72200012 Tm [(respo)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(nse,)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 16.98500061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 21.48500061 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 37.76200104 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 42.26200104 105.3219986 Tm [(controls)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 77.11499786 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 81.61499786 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 95.61599731 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 100.11599731 105.3219986 Tm [(tr)1(anspor)1(t)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 139.85099792 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 144.35099792 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 153.19299316 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 157.69299316 105.3219986 Tm [(low)1(-density)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 207.89599609 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 212.39599609 105.3219986 Tm [(lipop)1(rot)1(e)-1(in)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 259.96200562 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 264.46200562 105.3219986 Tm [(\()] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(LDL\)-d)1(e)-1(rived)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 55.27399826 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 59.77399826 120.92199707 Tm [(cholesterol)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 107.23100281 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 111.73100281 120.92199707 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 132.44200134 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 136.94200134 120.92199707 Tm [(a)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 141.91700745 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 146.41700745 120.92199707 Tm [(lysosome)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 186.89100647 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 191.39100647 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 200.46600342 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 204.96600342 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 218.96699524 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 223.46699524 120.92199707 Tm [(site)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 238.48800659 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 242.98800659 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 251.83000183 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 256.32998657 120.92199707 Tm [(est)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(erific)-1(a)1(tion.)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 45.1230011 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 49.6230011 136.52200317 Tm [(It)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 55.62200165 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 60.12200165 136.52200317 Tm [(func)-1(t)1(ions)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 100.02899933 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 104.52899933 136.52200317 Tm [(as)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 113.66999817 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 118.16999817 136.52200317 Tm [(an)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 128.69099426 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 133.19099426 136.52200317 Tm [(org)1(anizer)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 173.99000549 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 178.49000549 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 187.33200073 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 191.83200073 136.52200317 Tm [(a)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 196.80700684 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 201.30700684 136.52200317 Tm [(number)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 235.1230011 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 239.6230011 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 248.46499634 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 252.96499634 136.52200317 Tm [(criti)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(cal)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 11.88300037 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 16.38299942 152.12199402 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 51.85599899 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 56.35599899 152.12199402 Tm [(involved)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 92.72499847 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 97.22499847 152.12199402 Tm [(in)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 105.16600037 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 109.66600037 152.12199402 Tm [(at)1(tachment,)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 160.98100281 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 165.48100281 152.12199402 Tm [(migra)1(tion,)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 209.65899658 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 214.15899658 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 230.43600464 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 234.93600464 152.12199402 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 249.34599304 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 253.84599304 152.12199402 Tm [(sig)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(naling.)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 28.78000069 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 33.27999878 167.72200012 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 77.1289978 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 81.6289978 167.72200012 Tm [(in)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 89.56999969 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 94.06999969 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 109.52600098 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 114.02600098 167.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 135.54200745 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 140.04200745 167.72200012 Tm [(cause)-1(s)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 168.51400757 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 173.01400757 167.72200012 Tm [(a)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 177.98899841 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 182.48899841 167.72200012 Tm [(do)1(mi)-1(na)1(n)-1(t)1(,)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 226.38200378 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 230.88200378 167.72200012 Tm [(pulverul)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 0 183.32200623 Tm [(en)-1(t)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 14.00500011 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 18.50499916 183.32200623 Tm [(cata)1(rac)-1(t)1(.)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 54.76399994 183.32200623 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 187.94999695 cm q /GS2 gs 1 g 0.375 0.75 m 144.67500305 0.75 l 144.67500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 145.67500305 -0.25 l 145.67500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 280 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 281 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 145.42500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 145.42500305 16.35000038 l h f* Q q 1 0 0 1 145.05000305 0 cm -0.625 -0.25 m 278.375 -0.25 l 278.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 282 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB,)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IHC)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 37.09899902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 145.05000305 0.75 m 145.05000305 187.94999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 145.05000305 188.69999695 m 145.05000305 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 204.30000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 188.32499695 m 422.42498779 188.32499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 204.67500305 m 423.17498779 204.67500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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