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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 87.09300232 23.67700005 Tm 0 g [(CETN2)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 151.50300598 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 328.20700073 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(CET)-1(N)1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.94200134 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 96.19200134 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 180.19200134 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CET)-1(N)1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.94200134 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.31600189 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.51799774 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.89199829 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.87199402 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.2460022 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.72000122 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ce)1(n)-1(tr)1(i)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.28500366 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.65899658 12.82499981 Tm [(2;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.79000092 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.16400146 12.82499981 Tm [(CALT)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.17900085 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.55299377 12.82499981 Tm [(CEN2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.37800598 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 260.37298584 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(2-172)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.85600281 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.89100647 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.93200684 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.96699524 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.39801025 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.43301392 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.92599487 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.96099854 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.64700317 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 306.68200684 12.04500008 Tm [(CET)-1(N)1(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 330.63198853 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 289.31201172 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 317.25100708 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 345.19000244 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 373.1289978 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ce)-1(ntr)1(i)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.89599991 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.39599991 11.72200012 Tm [(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.67399979 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CALT;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.29700089 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.79700089 11.72200012 Tm [(CEN2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.36000061 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P41)-1(20)-1(8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(05)-1(33)-1(4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 106.625 16.35000038 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 105.875 0.75 l 105.875 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 106.875 -0.25 l 106.875 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 106.625 0.75 m 426.17498779 0.75 l 426.17498779 94.34999847 l 106.625 94.34999847 l h f* Q q 1 0 0 1 106.25 0 cm -0.625 -0.25 m 320.92498779 -0.25 l 320.92498779 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Calt)1(ractin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.96099854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.46099854 11.72200012 Tm [(belongs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.90100098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.40100098 11.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.47599792 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.97599792 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.9509964 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.4509964 11.72200012 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.53300476 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.03300476 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.875 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.375 11.72200012 Tm [(calc)-1(ium-b)1(i)-1(nd)1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.18200684 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.68200684 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.15499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.65499878 11.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.93200684 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.43200684 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.99301147 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.49301147 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.46798706 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 306.96798706 11.72200012 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(tr)1(u)-1(ctura)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.55400085 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.05400085 27.3220005 Tm [(component)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.74299622 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.24299622 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.08499908 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.58499908 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.58599854 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.08599854 27.3220005 Tm [(ce)-1(ntr)1(osome.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.35699463 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.85699463 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.66400146 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.16400146 27.3220005 Tm [(hig)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.39900208 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.89900208 27.3220005 Tm [(leve)-1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.62600708 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.12600708 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.96798706 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.46798706 27.3220005 Tm [(conse)-1(rv)1(ati)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 11.26799965 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.76799965 42.92200089 Tm [(fro)1(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.47900009 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.97900009 42.92200089 Tm [(alg)1(ae)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.18699646 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.68699646 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.76200104 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.26200104 42.92200089 Tm [(humans)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.46900177 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.96900177 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.2460022 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.7460022 42.92200089 Tm [(its)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.66000366 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.16000366 42.92200089 Tm [(asso)1(c)-1(iat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.08700562 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.58700562 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.98300171 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.48300171 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.48399353 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.98399353 42.92200089 Tm [(ce)-1(ntr)1(osome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.0880127 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 305.5880127 42.92200089 Tm [(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(uggest)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.54800034 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.04800034 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.27000046 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.76999664 58.52199936 Tm [(caltra)1(c)-1(t)1(i)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.22399902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.72399902 58.52199936 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.77099609 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.27099609 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.2460022 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.7460022 58.52199936 Tm [(funda)1(me)-1(nta)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.49699402 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.99699402 58.52199936 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.65699768 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.15699768 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.0980072 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.5980072 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.59899902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.09899902 58.52199936 Tm [(st)1(ruc)-1(ture)] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.55599976 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.05599976 58.52199936 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 74.12200165 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.9980011 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.4980011 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.34000015 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.84000015 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.84100342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.34100342 74.12200165 Tm [(mic)-1(r)1(otubule-org)1(anizing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.38200378 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.88200378 74.12200165 Tm [(ce)-1(nter,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.11000061 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.61000061 74.12200165 Tm [(po)1(ssibly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.71398926 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.21398926 74.12200165 Tm [(required)] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.75500488 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 303.25500488 74.12200165 Tm [(fo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 3.43700004 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.9369998 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.93799973 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.43799973 89.72200012 Tm [(pro)1(per)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.63499832 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.13499832 89.72200012 Tm [(duplicatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.47899628 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.97899628 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.2559967 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.7559967 89.72200012 Tm [(segregat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.07499695 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.57499695 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.41700745 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.91700745 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.91799927 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.41799927 89.72200012 Tm [(ce)-1(ntr)1(osome.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.68899536 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 0.75 m 106.25 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 17.10000038 m 106.25 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 33.45000076 m 106.25 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 49.80000305 m 106.25 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 66.15000153 m 106.25 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 82.5 m 106.25 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 98.84999847 m 106.25 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 106.25 115.19999695 m 106.25 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 208.79998779 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17498779 m 426.92498779 209.17498779 l S Q Q q 1 0 0 1 0 582.67901611 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q Q 1 0 0 -1 0 841.90002441 cm
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