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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</Lang (zh-CN) /MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 45.93399811 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <</MCID 1 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 117.69799805 23.67700005 Tm 0 Tr [(UHRF1)1(\(N-term)-1(\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 258.92599487 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABG 22 Tf 1 0 0 -1 369.36599731 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(UHRF1\(N-te)1(rm\))] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 163.40100098 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 215.90100098 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 226.40100098 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(U)1(HRF)-1(1\(N)1(-term)1(\))] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 150.00999451 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 152.38400269 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 181.15600586 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 183.52999878 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 233.85099792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 236.2250061 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 274.02099609 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ub)-1(iq)-1(ui)-1(tin)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 101.32900238 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 104.14199829 12.82499981 Tm [(li)-1(ke)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 118.95899963 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 121.77200317 12.82499981 Tm [(with)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 140.72099304 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 143.53399658 12.82499981 Tm [(PHD)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 161.96000671 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 164.772995 12.82499981 Tm [(and)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 180.83599854 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 183.64900208 12.82499981 Tm [(rin)-1(g)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 200.17799377 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 202.99099731 12.82499981 Tm [(fi)-1(nge)1(r)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 227.94900513 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 230.76199341 12.82499981 Tm [(do)-1(mains)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 267.26599121 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 270.07901001 12.82499981 Tm [(1;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 278.20999146 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 281.02301025 12.82499981 Tm [(Np95;)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 306.77099609 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 309.58401489 12.82499981 Tm [(hNP9)1(5;)] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 340.75601196 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 343.56900024 12.82499981 Tm [(ICBP90)1(;)] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 376.40200806 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 379.21499634 12.82499981 Tm [(RN)1(F)-1(106)1(;)] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 415.29299927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [(TD)-1(RD22)1(;)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 37.19100189 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 39.56499863 30.49699783 Tm [(hUHRF1;)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 77.01699829 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 79.39099884 30.49699783 Tm [(hu)-1(N)1(p)-1(95)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 113.36199951 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.97299194 cm /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(UHRF1\(N-te)1(rm\))] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 129.27600098 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 299.51199341 cm /P <</Lang (zh-CN) /MCID 83 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 84 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 333.05099487 cm /P <</Lang (zh-CN) /MCID 89 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 93 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 366.58999634 cm /P <</Lang (zh-CN) /MCID 98 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 99 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 400.1289978 m 416.75 400.1289978 l 416.75 431.32901001 l -1.45000005 431.32901001 l h f* Q q 1 0 0 1 0 400.1289978 cm /P <</MCID 104 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 105 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 431.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 108 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 141.67500305 156.75 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 156.75100708 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 161.25100708 11.72200012 Tm [(subf)1(amily)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 202.79299927 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 207.29299927 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 216.13499451 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 220.63499451 11.72200012 Tm [(RING)1(-finger)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 272.42001343 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(type)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 18.97100067 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 23.47100067 27.3220005 Tm [(E3)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 33.6969986 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 38.1969986 27.3220005 Tm [(ubiquitin)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 76.87799835 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 81.37799835 27.3220005 Tm [(ligases.)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 112.5039978 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 117.0039978 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 132.81100464 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 137.31100464 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 168.61799622 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 173.11799622 27.3220005 Tm [(binds)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 196.72999573 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 201.22999573 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 210.30499268 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 214.80499268 27.3220005 Tm [(speci)-1(f)1(ic)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 246.76199341 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 251.26199341 27.3220005 Tm [(DNA)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 271.76699829 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(seque)-1(nce)-1(s)1(,)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 47.18000031 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 51.68000031 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 67.95700073 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 72.45700073 42.92200089 Tm [(rec)-1(ruit)1(s)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 104.41000366 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 108.91000366 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 113.88500214 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 118.38500214 42.92200089 Tm [(hist)1(one)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 150.21499634 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 154.71499634 42.92200089 Tm [(deace)-1(t)1(yl)-1(a)1(se)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 204.93099976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 209.43099976 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 218.5059967 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 223.0059967 42.92200089 Tm [(regulat)1(e)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 258.68099976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 263.18099976 42.92200089 Tm [(g)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(en)-1(e)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 15.75899982 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 20.25900078 58.52199936 Tm [(expression.)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 68.3789978 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 72.8789978 58.52199936 Tm [(Its)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 83.04399872 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 87.54399872 58.52199936 Tm [(expression)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 133.4980011 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 137.9980011 58.52199936 Tm [(peaks)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 162.89300537 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 167.39300537 58.52199936 Tm [(at)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 175.72099304 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 180.22099304 58.52199936 Tm [(lat)1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 196.05000305 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 200.55000305 58.52199936 Tm [(G1)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 212.52099609 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 217.02099609 58.52199936 Tm [(ph)1(ase)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 242.55799866 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 247.05799866 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 263.33499146 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 267.83499146 58.52199936 Tm [(c)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ontinues)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 37.38000107 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 41.88000107 74.12200165 Tm [(during)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 70.31700134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 74.81700134 74.12200165 Tm [(G2)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 86.78800201 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 91.28800201 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 107.56500244 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 112.06500244 74.12200165 Tm [(M)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 120.85800171 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 125.35800171 74.12200165 Tm [(ph)1(ases)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 155.06100464 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 159.56100464 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 168.40299988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 172.90299988 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 186.90400696 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 191.40400696 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 205.81399536 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 210.31399536 74.12200165 Tm [(cy)-1(cle)-1(.)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 233.77200317 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 238.27200317 74.12200165 Tm [(It)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 244.27099609 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 248.77099609 74.12200165 Tm [(plays)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 270.81799316 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 4.9749999 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 9.47500038 89.72200012 Tm [(major)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 34.44499969 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 38.94499969 89.72200012 Tm [(role)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 55.60499954 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 60.10499954 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 68.04599762 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 72.54599762 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 86.54699707 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 91.04699707 89.72200012 Tm [(G1/S)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 112.05699921 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 116.55699921 89.72200012 Tm [(tr)1(ansition)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 157.44400024 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 161.94400024 89.72200012 Tm [(by)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 172.45599365 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 176.95599365 89.72200012 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 221.22200012 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 225.72200012 89.72200012 Tm [(to)1(poiso)1(me)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ras)1(e)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 17.68400002 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 22.18400002 105.3219986 Tm [(IIalp)1(ha)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 51.10900116 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 55.60900116 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 71.88600159 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 76.38600159 105.3219986 Tm [(retinobla)1(stoma)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 141.71099854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 146.21099854 105.3219986 Tm [(gene)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 167.727005 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 172.227005 105.3219986 Tm [(expression,)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 220.34700012 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 224.84700012 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 241.12399292 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 245.62399292 105.3219986 Tm [(func)-1(t)1(i)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ons)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 15.43400002 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 19.93400002 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 27.875 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 32.375 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 46.37599945 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 50.87599945 120.92199707 Tm [(p53)-1(-)1(dependen)-1(t)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 118.09899902 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 122.59899902 120.92199707 Tm [(DNA)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 143.10400391 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 147.60400391 120.92199707 Tm [(da)1(mage)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 182.60600281 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 187.10600281 120.92199707 Tm [(che)-1(ckpoint.)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 236.61000061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 241.11000061 120.92199707 Tm [(Multipl)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(e)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 5.10599995 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 9.60599995 136.52200317 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 50.52799988 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 55.02799988 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 88.59799957 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 93.09799957 136.52200317 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 133.44000244 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 137.94000244 136.52200317 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 174.88000488 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 179.38000488 136.52200317 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 216.53999329 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 221.03999329 136.52200317 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 241.38699341 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 245.88699341 136.52200317 Tm [(been)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 267.39401245 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 25.69000053 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 30.19000053 152.12199402 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 42.4679985 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 46.9679985 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 62.42399979 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 66.9240036 152.12199402 Tm [(gene)-1(.)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 90.60600281 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 284 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 285 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 286 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.1000061 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 288 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 293 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 294 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(UHRF1)-1(\(N)1(-term\))] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 67.16600037 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 189.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 0.75 m 141.30000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 157.5 m 141.30000305 173.1000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 173.8500061 m 141.30000305 189.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 189.45001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 173.4750061 m 422.42498779 173.4750061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 189.82501221 m 423.17498779 189.82501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 118 0 R/Length 31164>>stream
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