%PDF-1.5 %ÈÈÈÈÈÈ?1 0 obj <> endobj 2 0 obj <>/Metadata 127 0 R>> endobj 3 0 obj <> endobj 4 0 obj <>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>> endobj 5 0 obj <>stream 1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 66 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 71.76399994 23.67700005 Tm 0 Tr [(TXNRD1)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 152.16900635 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 262.60900879 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(TXNRD1)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 124.07700348 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 176.57699585 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.82699585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TXN)1(RD)-1(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.56099701 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.93499756 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.70700073 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.08099365 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.4019928 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.77600098 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.57200623 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000C000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(thi)-1(ore)1(d)-1(oxi)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.39299774 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.76699829 12.82499981 Tm [(re)1(d)-1(uctase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.00300598 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.3769989 12.82499981 Tm [(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.50799561 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.88200378 12.82499981 Tm [(TR;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.50900269 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.88299561 12.82499981 Tm [(TR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.83200073 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.20599365 12.82499981 Tm [(TXNR;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.06100464 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.43499756 12.82499981 Tm [(TRXR1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.53500366 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.90899658 12.82499981 Tm [(GRIM-12)] TJ ET EMC /P <> BDC BT 1 0 0 -1 305.71499634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011001200130010000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TXNRD1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.82700348 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001F002000210022000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Rat,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.85399628 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.22799683 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.58999634 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002300240025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800130026000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 203.55000305 l 0.375 203.55000305 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 105.3219986 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 105.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 203.55000305 l 141.67500305 203.55000305 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 204.55000305 l -0.625 204.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(belongs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.54499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.04499817 11.72200012 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.11999512 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.61999512 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.1210022 11.72200012 Tm [(pyridine)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.26800537 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(nuc)-1(leotid)1(e)-1(-)1(disulfide)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.97000122 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.47000122 27.3220005 Tm [(oxid)1(oreduc)-1(t)1(ase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.58599854 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.08599854 27.3220005 Tm [(fa)1(mi)-1(ly,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.33399963 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.83399963 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.11099243 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.61099243 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.17199707 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.67199707 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.64700317 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.14700317 27.3220005 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.41101074 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.34300041 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.84300041 42.92200089 Tm [(th)1(ioredoxin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.37799835 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.87799835 42.92200089 Tm [(\(Trx\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 105.04699707 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.54699707 42.92200089 Tm [(system.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.70199585 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.20199585 42.92200089 Tm [(Three)] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.55200195 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.05200195 42.92200089 Tm [(th)1(ioredoxin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.58700562 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.08700562 42.92200089 Tm [(reduc)-1(t)1(ase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.04598999 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(\(TrxR\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.04400063 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.54400063 58.52199936 Tm [(isoz)1(y)-1(mes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.72100067 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.22100067 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.73899841 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.23899841 58.52199936 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.92900085 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.42900085 58.52199936 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.36999512 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.86999512 58.52199936 Tm [(mammals.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.84599304 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.34599304 58.52199936 Tm [(TrxRs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.54499817 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.04499817 58.52199936 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.56300354 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.06300354 58.52199936 Tm [(sele)-1(nocyst)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ein)-1(e-conta)1(i)-1(ning)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.79399872 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.29399872 74.12200165 Tm [(flav)1(oe)-1(nz)1(y)-1(mes,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.94299316 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.44299316 74.12200165 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.53999329 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.03999329 74.12200165 Tm [(reduc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.50500488 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.00500488 74.12200165 Tm [(th)1(ioredoxins,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.87298584 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.37298584 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.51400757 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(well)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.00200081 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.50200081 89.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.64299965 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.14300156 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.30199814 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.80199814 89.72200012 Tm [(subst)1(rat)1(e)-1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.98400116 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.48400116 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.76100159 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.26100159 89.72200012 Tm [(play)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.14199829 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.64199829 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.61700439 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.11700439 89.72200012 Tm [(ke)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.88699341 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.38699341 89.72200012 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.04699707 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.54699707 89.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.48800659 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.98800659 89.72200012 Tm [(redox)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.57099915 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.07099915 89.72200012 Tm [(ho)1(mo)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(eosta)1(sis.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.21500015 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.71500015 105.3219986 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.97700119 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.47700119 105.3219986 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.99299622 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.49299622 105.3219986 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.41000366 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.91000366 105.3219986 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.43099976 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.93099976 105.3219986 Tm [(ubiquito)1(usly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.26300049 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.76300049 105.3219986 Tm [(expressed,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.08399963 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.58399963 105.3219986 Tm [(cy)-1(t)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(solic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.19099998 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.69099998 120.92199707 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.40200043 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.90200043 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.74399948 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.24399948 120.92199707 Tm [(TrxR,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.44300079 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.94300079 120.92199707 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.04000092 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.54000092 120.92199707 Tm [(func)-1(t)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.44700623 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.94700623 120.92199707 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.08799744 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.58799744 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.56300354 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.06300354 120.92199707 Tm [(ho)1(modimer)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.60899353 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.10899353 120.92199707 Tm [(contain)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.69799995 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.19799995 136.52200317 Tm [(FAD,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.33399963 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.83399963 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.11100006 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.61100006 136.52200317 Tm [(sele)-1(nocystein)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.60199738 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.102005 136.52200317 Tm [(\(Se)-1(c\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.92799377 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.42799377 136.52200317 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.7559967 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.2559967 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.25700378 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.75700378 136.52200317 Tm [(active)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.82299805 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.32299805 136.52200317 Tm [(site.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.50999451 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.00999451 136.52200317 Tm [(Se)-1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.82400513 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.32400513 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.88500977 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.50699997 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.00699997 152.12199402 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.51900101 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.01900101 152.12199402 Tm [(UG)1(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.76399994 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.26399994 152.12199402 Tm [(codon)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.52300262 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.02300262 152.12199402 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.24499512 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.74499512 152.12199402 Tm [(normally)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.41099548 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.91099548 152.12199402 Tm [(signals)] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.30999756 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.80999756 152.12199402 Tm [(tr)1(anslatio)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.67098999 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.17098999 152.12199402 Tm [(ter)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(minatio)1(n)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.53099823 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.03099823 167.72200012 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.83800125 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.33799744 167.72200012 Tm [(3')] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.92299652 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.42299652 167.72200012 Tm [(UTRs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.34300232 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.84300232 167.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.68499756 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.18499756 167.72200012 Tm [(sele)-1(nop)1(rotein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.53300476 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.03300476 167.72200012 Tm [(mRNA)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.15699768 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.65699768 167.72200012 Tm [(contain)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.70599365 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.20599365 167.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.18099976 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.68099976 167.72200012 Tm [(co)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 183.32200623 Tm [(nserve)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.84199905 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.34199905 183.32200623 Tm [(st)1(e)-1(m-)1(l)-1(o)1(op)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.8809967 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.3809967 183.32200623 Tm [(st)1(ruc)-1(ture,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.0039978 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.5039978 183.32200623 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.50500488 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.00500488 183.32200623 Tm [(Se)-1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.81900024 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.31900024 183.32200623 Tm [(inse)-1(r)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.98500061 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.48500061 183.32200623 Tm [(seque)-1(nce)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.33200073 183.32200623 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.83200073 183.32200623 Tm [(\(SE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 198.92199707 Tm [(CIS\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.86599922 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.36599922 198.92199707 Tm [(ele)-1(ment,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.57899857 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.07899857 198.92199707 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.1760025 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.6760025 198.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.23699951 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.73699951 198.92199707 Tm [(ne)-1(cessary)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.51600647 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.01600647 198.92199707 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.29400635 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.79400635 198.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.79499817 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.29499817 198.92199707 Tm [(rec)-1(o)1(gnition)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.78599548 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.28599548 198.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.12800598 198.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.62800598 198.92199707 Tm [(UG)1(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.37298584 198.92199707 Tm [( )] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 0.75 m 141.30000305 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 203.55000305 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 203.92500305 m 423.17498779 203.92500305 l S Q Q Q 1 0 0 -1 0 841.90002441 cm endstream endobj 6 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