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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 89.89099884 23.67700005 Tm 0 g [(CD)-1(14)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 137.70399475 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 148.70399475 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 325.4079895 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(CD14)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 85.70200348 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 90.95200348 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 174.95199585 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 180.20199585 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CD14)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 85.70200348 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 88.0759964 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 121.27799988 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 123.65200043 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 183.63200378 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 186.0059967 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 220.47999573 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130014000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 26 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 27 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 28 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0016000F>] TJ ET EMC /P <</MCID 29 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 30 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <</MCID 31 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 32 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <</MCID 33 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 139.85800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 180.95599365 m 416.75 180.95599365 l 416.75 212.1559906 l -1.45000005 212.1559906 l h f* Q q 1 0 0 1 0 180.95599365 cm /P <</MCID 35 >> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 240.09500122 m 416.75 240.09500122 l 416.75 258.03399658 l -1.45000005 258.03399658 l h f* Q q 1 0 0 1 0 240.09500122 cm /P <</MCID 39 >> BDC q /GS2 gs 1 g 0 1.25 m 28.15600014 1.25 l 28.15600014 16.68799973 l 0 16.68799973 l h f* Q q /GS2 gs 1 g 28.15600014 1.25 m 30.81900024 1.25 l 30.81900024 16.68799973 l 28.15600014 16.68799973 l h f* Q q /GS2 gs 1 g 30.81900024 1.25 m 62.12599945 1.25 l 62.12599945 16.68799973 l 30.81900024 16.68799973 l h f* Q q /GS2 gs 1 g 62.12599945 1.25 m 64.78900146 1.25 l 64.78900146 16.68799973 l 62.12599945 16.68799973 l h f* Q q /GS2 gs 1 g 64.78900146 1.25 m 127.63999939 1.25 l 127.63999939 16.68799973 l 64.78900146 16.68799973 l h f* Q q /GS2 gs 1 g 127.63999939 1.25 m 130.30299377 1.25 l 130.30299377 16.68799973 l 127.63999939 16.68799973 l h f* Q q /GS2 gs 1 g 130.30299377 1.25 m 139.37799072 1.25 l 139.37799072 16.68799973 l 130.30299377 16.68799973 l h f* Q q /GS2 gs 1 g 139.37800598 1.25 m 142.04100037 1.25 l 142.04100037 16.68799973 l 139.37800598 16.68799973 l h f* Q q /GS2 gs 1 g 142.04100037 1.25 m 147.01600647 1.25 l 147.01600647 16.68799973 l 142.04100037 16.68799973 l h f* Q q /GS2 gs 1 g 147.01600647 1.25 m 149.67900085 1.25 l 149.67900085 16.68799973 l 147.01600647 16.68799973 l h f* Q q /GS2 gs 1 g 149.67900085 1.25 m 177.64100647 1.25 l 177.64100647 16.68799973 l 149.67900085 16.68799973 l h f* Q q /GS2 gs 1 g 177.64100647 1.25 m 180.30400085 1.25 l 180.30400085 16.68799973 l 177.64100647 16.68799973 l h f* Q q /GS2 gs 1 g 180.30400085 1.25 m 212.58599854 1.25 l 212.58599854 16.68799973 l 180.30400085 16.68799973 l h f* Q q /GS2 gs 1 g 212.58599854 1.25 m 215.24899292 1.25 l 215.24899292 16.68799973 l 212.58599854 16.68799973 l h f* Q q /GS2 gs 1 g 215.24899292 1.25 m 235.95999146 1.25 l 235.95999146 16.68799973 l 215.24899292 16.68799973 l h f* Q q /GS2 gs 1 g 235.96000671 1.25 m 238.6230011 1.25 l 238.6230011 16.68799973 l 235.96000671 16.68799973 l h f* Q q /GS2 gs 1 g 238.6230011 1.25 m 268.90600586 1.25 l 268.90600586 16.68799973 l 238.6230011 16.68799973 l h f* Q q /GS2 gs 1 g 268.90600586 1.25 m 271.56900024 1.25 l 271.56900024 16.68799973 l 268.90600586 16.68799973 l h f* Q q /GS2 gs 1 g 271.56900024 1.25 m 298.63900757 1.25 l 298.63900757 16.68799973 l 271.56900024 16.68799973 l h f* Q q /GS2 gs 1 g 298.63900757 1.25 m 301.30200195 1.25 l 301.30200195 16.68799973 l 298.63900757 16.68799973 l h f* Q q /GS2 gs 1 g 301.30200195 1.25 m 323.10800171 1.25 l 323.10800171 16.68799973 l 301.30200195 16.68799973 l h f* Q q /GS2 gs 1 g 323.10800171 1.25 m 325.77099609 1.25 l 325.77099609 16.68799973 l 323.10800171 16.68799973 l h f* Q q /GS2 gs 1 g 325.77099609 1.25 m 334.61300659 1.25 l 334.61300659 16.68799973 l 325.77099609 16.68799973 l h f* Q q /GS2 gs 1 g 334.61300659 1.25 m 337.27600098 1.25 l 337.27600098 16.68799973 l 334.61300659 16.68799973 l h f* Q q /GS2 gs 1 g 337.27600098 1.25 m 367.3170166 1.25 l 367.3170166 16.68799973 l 337.27600098 16.68799973 l h f* Q q /GS2 gs 1 g 367.31698608 1.25 m 369.97998047 1.25 l 369.97998047 16.68799973 l 367.31698608 16.68799973 l h f* Q q /GS2 gs 1 g 369.98001099 1.25 m 393.41201782 1.25 l 393.41201782 16.68799973 l 369.98001099 16.68799973 l h f* Q EMC /P <</MCID 40 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 12.89099979 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 28.15600014 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 30.81900024 12.89099979 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 62.12599945 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 64.78900146 12.89099979 Tm [(correspond)1(i)-1(ng)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 127.63999939 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 130.30299377 12.89099979 Tm [(to)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 139.37800598 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 142.04100037 12.89099979 Tm [(a)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 147.01600647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 149.67900085 12.89099979 Tm [(region)] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 177.64100647 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 180.30400085 12.89099979 Tm [(derived)] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 212.58599854 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 215.24899292 12.89099979 Tm [(fro)1(m)] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 235.96000671 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 238.6230011 12.89099979 Tm [(20)-1(-)1(3)-1(45)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 268.90600586 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 271.56900024 12.89099979 Tm [(amino)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 298.63900757 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 301.30200195 12.89099979 Tm [(acids)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 323.10800171 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 325.77099609 12.89099979 Tm [(of)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 334.61300659 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 337.27600098 12.89099979 Tm [(human)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 367.31698608 12.89099979 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 369.98001099 12.89099979 Tm [(CD14)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 393.4119873 12.89099979 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 258.03399658 m 416.75 258.03399658 l 416.75 289.23400879 l -1.45000005 289.23400879 l h f* Q q 1 0 0 1 0 258.03399658 cm /P <</MCID 68 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 289.23400879 m 416.75 289.23400879 l 416.75 320.434021 l -1.45000005 320.434021 l h f* Q q 1 0 0 1 0 289.23400879 cm /P <</MCID 69 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 320.43399048 cm /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 348.37298584 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 73 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 123.27500153 16.35000038 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 77 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CD14)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 23.43199921 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 27.93199921 11.72200012 Tm [(molec)-1(ule)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 67.14900208 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 81 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 82 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 123.27500153 16.35000038 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P08)-1(57)-1(1)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 123.27500153 16.35000038 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(10)-1(50)-1(7)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 123.27500153 16.35000038 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 123.27500153 16.35000038 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 117 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 118 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 123.27500153 16.35000038 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 119 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 122.52500153 0.75 l 122.52500153 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 123.52500153 -0.25 l 123.52500153 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 132 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 123.27500153 0.75 m 422.42498779 0.75 l 422.42498779 78.75 l 123.27500153 78.75 l h f* Q q 1 0 0 1 122.90000153 0 cm -0.625 -0.25 m 300.5249939 -0.25 l 300.5249939 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 133 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(surfa)1(c)-1(e)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 210.5039978 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 215.0039978 11.72200012 Tm [(antig)1(e)-1(n)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 247.68200684 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 252.18200684 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 269.4039917 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 273.9039917 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 280.46499634 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 284.96499634 11.72200012 Tm [(p)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(refere)-1(nt)1(ially)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 51.13499832 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 55.63499832 27.3220005 Tm [(expressed)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 98.78900146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 103.28900146 27.3220005 Tm [(on)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 114.55699921 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 119.05699921 27.3220005 Tm [(monocytes/)-1(ma)1(c)-1(ro)1(pha)1(ges.)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 230.76600647 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 235.26600647 27.3220005 Tm [(It)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 241.26499939 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 245.76499939 27.3220005 Tm [(cooperat)1(e)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(s)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 4.16599989 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 8.66600037 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 27.06200027 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 31.56200027 42.92200089 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 54.72100067 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 59.22100067 42.92200089 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 94.69400024 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 99.19400024 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 108.26899719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 112.76899719 42.92200089 Tm [(mediat)1(e)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 147.89399719 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 152.39399719 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 166.39500427 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 170.89500427 42.92200089 Tm [(inn)-1(a)1(te)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 197.81599426 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 202.31599426 42.92200089 Tm [(immun)-1(e)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 237.7749939 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 242.2749939 42.92200089 Tm [(response)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 281.27200317 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 285.77200317 42.92200089 Tm [(t)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(o)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 5.72200012 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 10.22200012 58.52199936 Tm [(ba)1(c)-1(t)1(e)-1(ria)1(l)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 47.11800003 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 51.61800003 58.52199936 Tm [(lipop)1(olysac)-1(cha)1(ride.)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 134.05099487 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 138.55099487 58.52199936 Tm [(Alt)1(e)-1(rna)1(tive)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 185.27400208 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 189.77400208 58.52199936 Tm [(splicin)-1(g)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 222.68899536 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 227.18899536 58.52199936 Tm [(results)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 255.35800171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 259.85800171 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 267.79901123 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 272.29901123 58.52199936 Tm [(mult)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(iple)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 15.64500046 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 20.14500046 74.12200165 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 61.06700134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 65.56700134 74.12200165 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 99.13700104 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 103.63700104 74.12200165 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 143.97900391 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 148.47900391 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 162.47999573 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 166.97999573 74.12200165 Tm [(same)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 189.66000366 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 194.16000366 74.12200165 Tm [(pro)1(tein)-1(.)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 227.63299561 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 176.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 0.75 m 122.90000153 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 17.10000038 m 122.90000153 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 33.45000076 m 122.90000153 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 49.80000305 m 122.90000153 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 66.15000153 m 122.90000153 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 82.5 m 122.90000153 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 122.90000153 98.84999847 m 122.90000153 176.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 176.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 177.2250061 m 423.17498779 177.2250061 l S Q Q q 1 0 0 1 0 525.97302246 cm /P <</MCID 219 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 553.9119873 cm /P <</MCID 220 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 581.85101318 cm /P <</MCID 221 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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6 0 obj
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