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(zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(TT)-1(K)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 104.93800354 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 157.43800354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 162.68800354 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TTK)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 99.42199707 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 101.79599762 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 130.56799316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 132.94200134 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 183.26300049 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 185.63699341 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 223.43299866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TT)-1(K)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 78.68800354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 81.06199646 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 112.44400024 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 114.81800079 12.82499981 Tm [(kinas)-1(e)1(;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 144.68800354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 147.06199646 12.82499981 Tm [(ES)-1(K)1(;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 165.27799988 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 167.6519928 12.82499981 Tm [(PYT;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 186.1190033 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 188.49299622 12.82499981 Tm [(CT)-1(9)1(6;)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 212.66099548 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 215.03500366 12.82499981 Tm [(MPH1)1(;)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 244.11000061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 246.48399353 12.82499981 Tm [(MPS1;)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 273.84100342 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 276.21499634 12.82499981 Tm [(MPS1L1)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 310.49899292 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 49 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 50 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 51 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 52 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 64 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 65 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TT)-1(K)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 78.68800354 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002300240025000E>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABG 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 83 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 146.17500305 0.75 l 146.17500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 147.17500305 -0.25 l 147.17500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 86 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 146.92500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 146.92500305 156.75 l h f* Q q 1 0 0 1 146.55000305 0 cm -0.625 -0.25 m 276.875 -0.25 l 276.875 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 88 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(dual)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 116.34200287 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 120.84200287 11.72200012 Tm [(speci)-1(f)1(ic)-1(it)1(y)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 163.31100464 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 167.81100464 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 199.11799622 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 203.61799622 11.72200012 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 230.70599365 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 235.20599365 11.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 253.602005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 258.10198975 11.72200012 Tm [(th)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(e)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 5.10599995 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 9.60599995 27.3220005 Tm [(ab)1(i)-1(lit)1(y)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 35.63000107 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 40.13000107 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 49.20500183 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 53.70500183 27.3220005 Tm [(ph)1(osph)1(orylate)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 115.92299652 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 120.42299652 27.3220005 Tm [(tyro)1(sin)-1(e,)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 157.07800293 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 161.57800293 27.3220005 Tm [(serine)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 187.33399963 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 191.83399963 27.3220005 Tm [(and)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 208.11099243 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 212.61099243 27.3220005 Tm [(th)1(re)-1(o)1(ni)-1(ne.)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 256.52999878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 261.02999878 27.3220005 Tm [(A)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ssociat)1(e)-1(d)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 40.15299988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 44.65299988 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 63.04899979 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 67.5490036 42.92200089 Tm [(ce)-1(ll)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 81.95899963 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 86.45899963 42.92200089 Tm [(pro)1(life)-1(r)1(ation,)] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 141.9750061 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 146.4750061 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 161.93099976 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 166.43099976 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 197.73800659 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 202.23800659 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 208.79899597 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 213.29899597 42.92200089 Tm [(esse)-1(nt)1(ial)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 250.50700378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 255.00700378 42.92200089 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 267.28500366 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 56.79499817 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 61.29499817 58.52199936 Tm [(alignment)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 104.8010025 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 109.3010025 58.52199936 Tm [(at)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 117.6289978 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 122.1289978 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 136.13000488 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 140.63000488 58.52199936 Tm [(ce)-1(ntr)1(ome)-1(r)1(e)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 190.38900757 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 194.88900757 58.52199936 Tm [(during)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 223.32600403 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 227.82600403 58.52199936 Tm [(mito)1(sis)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 258.45599365 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 262.95599365 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(nd)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 11.30300045 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 15.80300045 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 22.36400032 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 26.86400032 74.12200165 Tm [(required)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 63.40499878 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 67.90499878 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 80.18299866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 84.68299866 74.12200165 Tm [(ce)-1(ntr)1(osome)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 135.78700256 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 140.28700256 74.12200165 Tm [(duplicatio)1(n)-1(.)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 190.79800415 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 195.29800415 74.12200165 Tm [(It)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 201.29699707 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 205.79699707 74.12200165 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 220.47900391 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 224.97900391 74.12200165 Tm [(been)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 246.48599243 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 250.98599243 74.12200165 Tm [(fo)1(u)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(nd)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 11.30300045 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 15.80300045 89.72200012 Tm [(to)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 24.87800026 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 29.37800026 89.72200012 Tm [(be)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 40.23199844 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 44.73199844 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 49.70700073 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 54.20700073 89.72200012 Tm [(critic)-1(a)1(l)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 82.18299866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 86.68299866 89.72200012 Tm [(mito)1(tic)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 116.84700012 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 121.34700012 89.72200012 Tm [(che)-1(ckpoint)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 168.68499756 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 173.18499756 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 204.49200439 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 208.99200439 89.72200012 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 221.27000427 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 225.77000427 89.72200012 Tm [(acc)-1(ura)1(te)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 262.18701172 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(segregat)1(ion)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 51.31900024 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 55.81900024 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 64.66100311 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 69.16100311 105.3219986 Tm [(chromos)1(ome)-1(s)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 130.12199402 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 134.62199402 105.3219986 Tm [(during)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 163.05900574 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 167.55900574 105.3219986 Tm [(mito)1(sis.)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 200.35499573 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 204.85499573 105.3219986 Tm [(Tumorigene)-1(sis)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 267.78900146 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(may)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 18.17099953 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 22.67099953 120.92199707 Tm [(occ)-1(ur)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 46.40100098 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 50.90100098 120.92199707 Tm [(wh)1(e)-1(n)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 74.2009964 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 78.7009964 120.92199707 Tm [(th)1(is)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 94.15699768 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 98.65699768 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 129.96400452 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 134.46400452 120.92199707 Tm [(fa)1(i)-1(ls)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 151.51499939 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 156.01499939 120.92199707 Tm [(to)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 165.08999634 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 169.58999634 120.92199707 Tm [(degra)1(de)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 205.48500061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 209.98500061 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 226.26199341 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 230.76199341 120.92199707 Tm [(pro)1(duc)-1(e)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(s)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 4.16599989 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 8.66600037 136.52200317 Tm [(exc)-1(ess)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 36.2859993 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 40.7859993 136.52200317 Tm [(ce)-1(ntr)1(osomes)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 96.05599976 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 100.55599976 136.52200317 Tm [(resulting)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 138.25700378 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 142.75700378 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 150.69799805 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 155.19799805 136.52200317 Tm [(ab)1(e)-1(rr)1(ant)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 191.77400208 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 196.27400208 136.52200317 Tm [(mito)1(tic)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 226.43800354 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 230.93800354 136.52200317 Tm [(spindles.)] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 268.38400269 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(Alt)1(e)-1(rna)1(tive)] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 46.72299957 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 51.22299957 152.12199402 Tm [(splicin)-1(g)] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 84.13800049 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 88.63800049 152.12199402 Tm [(results)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 116.80699921 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 121.30699921 152.12199402 Tm [(in)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 129.2480011 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 133.7480011 152.12199402 Tm [(multiple)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 169.11999512 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 173.61999512 152.12199402 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 214.54200745 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 219.04200745 152.12199402 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 254.77799988 152.12199402 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 156.75 cm q 1 g 0.375 0.75 m 146.17500305 0.75 l 146.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.17500305 -0.25 l 147.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 257 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 258 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 146.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 146.92500305 16.35000038 l h f* Q q 1 0 0 1 146.55000305 0 cm -0.625 -0.25 m 276.875 -0.25 l 276.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 259 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.1000061 cm q 1 g 0.375 0.75 m 146.17500305 0.75 l 146.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.17500305 -0.25 l 147.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 261 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 266 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 146.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 146.92500305 16.35000038 l h f* Q q 1 0 0 1 146.55000305 0 cm -0.625 -0.25 m 276.875 -0.25 l 276.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 267 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(TTK)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 16.03100014 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 189.44999695 cm q 1 g 0.375 0.75 m 146.17500305 0.75 l 146.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 147.17500305 -0.25 l 147.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 269 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 270 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 146.92500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 146.92500305 16.35000038 l h f* Q q 1 0 0 1 146.55000305 0 cm -0.625 -0.25 m 276.875 -0.25 l 276.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 271 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(TTK)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 132.3769989 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 205.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 146.55000305 0.75 m 146.55000305 156.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 146.55000305 157.5 m 146.55000305 173.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 146.55000305 173.8500061 m 146.55000305 189.45001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 146.55000305 190.20001221 m 146.55000305 205.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 205.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.125 m 422.42498779 157.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 173.4750061 m 422.42498779 173.4750061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 189.82501221 m 422.42498779 189.82501221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 206.17501831 m 423.17498779 206.17501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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