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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 91.64199829 23.67700005 Tm 0 g [(CC)-1(N)1(K)] TJ ET EMC /P <> BDC BT /FAAABE 22 Tf 1 0 0 -1 146.95399475 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 323.6579895 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 41.20000076 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 69.13899994 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(CCNK)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.93000031 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 81.18000031 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 165.17999268 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 102.6780014 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(CCNK)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.93000031 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.30400085 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.5059967 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.87999725 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.86000061 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.23399353 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.70799255 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 136.21699524 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [(cy)1(cl)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.46900177 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.84300232 12.82499981 Tm [(K;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.10800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.48200226 12.82499981 Tm [(CPR4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.52799988 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 169.7559967 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 97.85800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 118.85800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 203.29499817 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F00030004>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 73.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 231.23399353 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 259.17300415 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 305.05099487 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(155-3)1(54)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(CCNK)] TJ ET EMC /P <> BDC BT 1 0 0 -1 335.88900757 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 333.98999023 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 361.9289856 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 389.86801147 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 417.80700684 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(cy)-1(clin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.12599945 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.62599945 11.72200012 Tm [(K)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.3390007 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CPR4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(O75)-1(90)-1(9)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(15)-1(93)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 114.17500305 16.35000038 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 113.42500305 0.75 l 113.42500305 78.75 l 0.375 78.75 l h f* Q q -0.625 -0.25 m 114.42500305 -0.25 l 114.42500305 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 42.92200089 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 114.17500305 0.75 m 426.17498779 0.75 l 426.17498779 78.75 l 114.17500305 78.75 l h f* Q q 1 0 0 1 113.80000305 0 cm -0.625 -0.25 m 313.375 -0.25 l 313.375 79.75 l -0.625 79.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(tr)1(ansc)-1(rip)1(tio)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.546 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.04599953 27.3220005 Tm [(cy)-1(clin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.17200089 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.67200089 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.91999817 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.41999817 27.3220005 Tm [(These)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.5 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101 27.3220005 Tm [(cy)-1(clin)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.29200745 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.79200745 27.3220005 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.96299744 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.46299744 27.3220005 Tm [(regulat)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.13800049 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.63800049 27.3220005 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.22200012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.72200012 27.3220005 Tm [(th)1(rough)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.61898804 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.11898804 27.3220005 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(eir)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.93799973 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.43799973 42.92200089 Tm [(asso)1(c)-1(iat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.36500168 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.86499786 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.26100159 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.76100159 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.03800201 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.53800201 42.92200089 Tm [(activat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.48800659 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.98800659 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.83000183 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.33000183 42.92200089 Tm [(cy)-1(clin)-1(-)1(depen)-1(d)1(e)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.375 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.875 42.92200089 Tm [(ki)-1(na)1(se)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.1289978 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.6289978 42.92200089 Tm [(\(CD)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(K\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.71899986 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.21899986 58.52199936 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.44099998 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.94100189 58.52199936 Tm [(ph)1(osph)1(orylate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.15899658 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.65899658 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.66000366 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.16000366 58.52199936 Tm [(C-t)1(e)-1(r)1(min)-1(a)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.71400452 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.21400452 58.52199936 Tm [(do)1(main)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.04100037 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.54100037 58.52199936 Tm [(\(CTD\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.58799744 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.08799744 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.92999268 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.42999268 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 263.43099976 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.93099976 58.52199936 Tm [(larg)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.6000061 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.1000061 58.52199936 Tm [(su)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(bunit)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.58799934 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.08799934 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.93000031 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.43000031 74.12200165 Tm [(RNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.95500183 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.45500183 74.12200165 Tm [(po)1(l)-1(ymerase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.30699921 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.80699921 74.12200165 Tm [(II.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.26499939 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.76499939 74.12200165 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.0269928 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.5269928 74.12200165 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.04299927 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.54299927 74.12200165 Tm [(pro)1(duc)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.61799622 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.11799622 74.12200165 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.28900146 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.78900146 74.12200165 Tm [(play)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.67001343 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.17001343 74.12200165 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.14498901 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.64498901 74.12200165 Tm [(dual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.31698608 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 294.81698608 74.12200165 Tm [(ro)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 0.75 m 113.80000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 17.10000038 m 113.80000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 33.45000076 m 113.80000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 49.80000305 m 113.80000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 66.15000153 m 113.80000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 82.5 m 113.80000305 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 98.84999847 m 113.80000305 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 113.80000305 115.19999695 m 113.80000305 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 193.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 193.57499695 m 426.92498779 193.57499695 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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