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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 86.96399689 23.67700005 Tm 0 g [(CC)-1(M2)] TJ ET EMC /P <</MCID 1 >> BDC BT 1 0 0 -1 140.63200378 23.67700005 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 2 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 151.63200378 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 3 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 328.33599854 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 4 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(CCM2)] TJ ET EMC /P <</MCID 7 >> BDC BT 1 0 0 -1 88.4960022 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 93.7460022 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 177.7460022 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CCM2)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 88.4960022 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 90.87000275 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 124.0719986 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 126.44599915 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 186.42599487 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 188.80000305 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 223.27400208 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 47.25 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CCM2)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 88.4960022 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 90.87000275 12.82499981 Tm [(scaffo)-1(ld)-1(ing)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 137.18699646 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 139.56100464 12.82499981 Tm [(protein)-1(;)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 173.75300598 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 176.1269989 12.82499981 Tm [(OS)-1(M;)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 199.69000244 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 202.06399536 12.82499981 Tm [(C7orf22;)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 238.83999634 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 241.21400452 12.82499981 Tm [(PP)1(10187)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 278.67199707 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 36 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 37 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 38 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 39 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 47.25 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 40 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 41 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 208.89500427 cm /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 236.83399963 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 282.71200562 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 53 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(245-4)1(44)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(CCM2)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 337.66000366 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 311.65100098 cm /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 339.58999634 cm /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 367.5289917 cm /P <</MCID 84 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 395.46798706 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 85 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 87.67500305 16.35000038 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CCM2)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 26.11199951 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 30.61199951 11.72200012 Tm [(scaff)1(olding)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 78.07700348 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 82.57700348 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 113.88400269 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 96 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 87.67500305 16.35000038 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 97 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(OSM;)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 23.48900032 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 27.98900032 11.72200012 Tm [(C7orf22;)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 64.28800201 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 68.78800201 11.72200012 Tm [(PP101)-1(87)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 106.19000244 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 104 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 87.67500305 16.35000038 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 105 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9B)-1(SQ5)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 36.06600189 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 87.67500305 16.35000038 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(04)-1(90)-1(3)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 114 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 87.67500305 16.35000038 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 115 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(syste)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(m:)] TJ ET EMC /P <</MCID 135 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 11.40799999 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 31.95000076 l 87.67500305 31.95000076 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 136 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 47.53099823 19.52199936 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 52.03099823 19.52199936 Tm [(coli)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 67.05599976 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 113.69999695 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 140 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 141 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 87.67500305 16.35000038 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 142 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 130.05000305 cm q /GS2 gs 1 g 0.375 0.75 m 86.92500305 0.75 l 86.92500305 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 87.92500305 -0.25 l 87.92500305 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 154 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 50.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 155 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 87.67500305 0.75 m 426.17498779 0.75 l 426.17498779 94.34999847 l 87.67500305 94.34999847 l h f* Q q 1 0 0 1 87.30000305 0 cm -0.625 -0.25 m 339.875 -0.25 l 339.875 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(scaff)1(old)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 131.43800354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 135.93800354 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 167.24499512 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 171.74499512 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 188.96699524 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 193.46699524 11.72200012 Tm [(func)-1(t)1(ions)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 233.37399292 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 237.87399292 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 245.81500244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 250.31500244 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 264.31600952 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 268.81600952 11.72200012 Tm [(st)1(re)-1(ss)1(-activat)1(e)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(d)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 5.75699997 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 10.25699997 27.3220005 Tm [(p38)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 26.56100082 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 31.06100082 27.3220005 Tm [(Mito)1(gen)-1(-)1(ac)-1(t)1(ivat)1(e)-1(d)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 110.77799988 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 115.27799988 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 146.58500671 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 151.08500671 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 178.17300415 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 182.67300415 27.3220005 Tm [(\(MAP)1(K\))] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 215.02999878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 219.52999878 27.3220005 Tm [(signaling)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 258.46099854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 262.96099854 27.3220005 Tm [(casc)-1(a)1(de.)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 299.13198853 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 303.63198853 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 319.43899536 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 323.93899536 27.3220005 Tm [(p)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(rot)1(e)-1(in)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 25.55900002 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 30.05900002 42.92200089 Tm [(interacts)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 66.90299988 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 71.40299988 42.92200089 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 89.7990036 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 94.2990036 42.92200089 Tm [(SMAD)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 121.47499847 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 125.97499847 42.92200089 Tm [(speci)-1(f)1(ic)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 157.93200684 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 162.43200684 42.92200089 Tm [(E3)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 172.65800476 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 177.15800476 42.92200089 Tm [(ubiquitin)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 215.83900452 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 220.33900452 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 251.64599609 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 256.14599609 42.92200089 Tm [(ligas)1(e)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 280.94000244 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 285.44000244 42.92200089 Tm [(1)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 290.71798706 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 295.21798706 42.92200089 Tm [(\(also)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 315.48098755 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 319.98098755 42.92200089 Tm [(kn)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ow)1(n)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 18.37400055 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 22.87400055 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 32.01499939 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 36.51499939 58.52199936 Tm [(SMURF1\))] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 76.16200256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 80.66200256 58.52199936 Tm [(via)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 92.7559967 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 97.2559967 58.52199936 Tm [(a)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 102.23100281 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 106.73100281 58.52199936 Tm [(ph)1(osph)1(otyros)1(i)-1(ne)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 179.40800476 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 183.90800476 58.52199936 Tm [(binding)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 217.05200195 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 221.55200195 58.52199936 Tm [(do)1(main)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 254.3789978 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 258.8789978 58.52199936 Tm [(to)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 267.95401001 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 272.45401001 58.52199936 Tm [(pro)1(mote)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 309.9750061 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 314.4750061 58.52199936 Tm [(Rho)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(A)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 6.33300018 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 10.83300018 74.12200165 Tm [(degra)1(dat)1(ion.)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 65.77799988 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 70.27799988 74.12200165 Tm [(The)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 86.08499908 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 90.58499908 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 121.89199829 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 126.39199829 74.12200165 Tm [(is)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 132.95300293 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 137.45300293 74.12200165 Tm [(required)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 173.9940033 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 178.4940033 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 190.77200317 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 195.27200317 74.12200165 Tm [(normal)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 225.77900696 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 230.27900696 74.12200165 Tm [(cy)-1(t)1(oske)-1(letal)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 281.02700806 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 285.52700806 74.12200165 Tm [(st)1(ruc)-1(ture,)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 326.1499939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ce)-1(ll-ce)-1(ll)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 32.71300125 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 37.21300125 89.72200012 Tm [(interactions,)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 89.88600159 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 94.38600159 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 110.66300201 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 115.16300201 89.72200012 Tm [(lume)-1(n)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 142.18899536 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 146.68899536 89.72200012 Tm [(fo)1(rmatio)1(n)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 189.39100647 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 193.89100647 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 201.83200073 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 206.33200073 89.72200012 Tm [(en)-1(d)1(oth)1(e)-1(lial)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 254.62399292 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 259.12399292 89.72200012 Tm [(ce)-1(lls.)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 279.86599731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 284.36599731 89.72200012 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 328.21499634 89.72200012 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 0.75 m 87.30000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 17.10000038 m 87.30000305 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 33.45000076 m 87.30000305 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 49.80000305 m 87.30000305 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 66.15000153 m 87.30000305 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 82.5 m 87.30000305 113.69999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 114.44999695 m 87.30000305 130.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 87.30000305 130.80000305 m 87.30000305 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.54998779 0.75 m 426.54998779 224.3999939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.07499695 m 426.17498779 114.07499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 130.42500305 m 426.17498779 130.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 224.7749939 m 426.92498779 224.7749939 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
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