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0 g [<000A000B000C000D000E>] TJ ET EMC /P <</Lang (zh-CN) /MCID 5 >> BDC BT 1 0 0 -1 52.5 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 6 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 86.625 12.82499981 Tm [(TRPM8)] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 119.79100037 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 172.29100037 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 9 >> BDC BT 1 0 0 -1 177.54100037 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 10 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 11 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TRP)1(M8)] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 114.27500153 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 116.64900208 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 145.42100525 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 147.79499817 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 198.11599731 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 200.49000549 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 238.28599548 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 20 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010>] TJ ET EMC /P <</MCID 21 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 22 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 23 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(transi)-1(e)1(n)-1(t)] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 101.4980011 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 107.45300293 12.82499981 Tm [(re)1(ceptor)] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 144.23399353 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 150.18899536 12.82499981 Tm [(po)-1(te)1(n)-1(tial)] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 188.86700439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 194.82200623 12.82499981 Tm [(catio)-1(n)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 221.27200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 227.227005 12.82499981 Tm [(chan)-1(nel)] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 260.88000488 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 266.83499146 12.82499981 Tm [(su)-1(bfamil)-1(y)] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 308.16799927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 314.12298584 12.82499981 Tm [(M)] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 323.1000061 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 329.05499268 12.82499981 Tm [(me)1(mb)-1(e)1(r)] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 365.45599365 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 371.41101074 12.82499981 Tm [(8;)] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 379.54199219 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 385.49700928 12.82499981 Tm [(TRPP)1(8;)] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 415.29501343 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 0 30.49699783 Tm [(LT)-1(RP)1(C6;)] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 34.38600159 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 36.75999832 30.49699783 Tm [(trp-p)-1(8)1(;)] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 66.31700134 30.49699783 Tm [( )] TJ ET EMC /P <</MCID 48 >> BDC BT 1 0 0 -1 68.69100189 30.49699783 Tm [(LT)-1(r)1(p)-1(C-6)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 101.53399658 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 57 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 58 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 60 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.97299194 cm /P <</Lang (zh-CN) /MCID 70 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <</MCID 71 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 72 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 73 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TRPM8)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 93.54100037 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 299.51199341 cm /P <</Lang (zh-CN) /MCID 76 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 77 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 333.05099487 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002300240025000E>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 366.58999634 cm /P <</Lang (zh-CN) /MCID 85 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 400.1289978 m 416.75 400.1289978 l 416.75 431.32901001 l -1.45000005 431.32901001 l h f* Q q 1 0 0 1 0 400.1289978 cm /P <</MCID 91 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 92 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 431.32901001 cm q 1 g 0.375 0.75 m 137.92500305 0.75 l 137.92500305 187.94999695 l 0.375 187.94999695 l h f* Q q -0.625 -0.25 m 138.92500305 -0.25 l 138.92500305 188.94999695 l -0.625 188.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 97.52200317 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 97.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 138.67500305 0.75 m 422.42498779 0.75 l 422.42498779 187.94999695 l 138.67500305 187.94999695 l h f* Q q 1 0 0 1 138.30000305 0 cm -0.625 -0.25 m 285.125 -0.25 l 285.125 188.94999695 l -0.625 188.94999695 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Rec)-1(ept)1(or-)1(ac)-1(t)1(ivated)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 81.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 86.40499878 11.72200012 Tm [(non-sele)-1(ctive)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 143.97799683 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 148.47799683 11.72200012 Tm [(cation)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 174.98100281 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 179.48100281 11.72200012 Tm [(channe)-1(l)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 213.10400391 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 217.60400391 11.72200012 Tm [(involved)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 253.9730072 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 258.47299194 11.72200012 Tm [(in)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 266.41400146 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 270.91400146 11.72200012 Tm [(d)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(etec)-1(t)1(ion)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 35.09500122 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 39.59500122 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 48.43700027 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 52.93700027 27.3220005 Tm [(sensations)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 98.07800293 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 102.57800293 27.3220005 Tm [(suc)-1(h)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 122.34500122 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 126.84500122 27.3220005 Tm [(as)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 135.98599243 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 140.48599243 27.3220005 Tm [(coolne)-1(ss)1(,)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 179.98800659 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 184.48800659 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 199.5 27.3220005 Tm [(being)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 224.05200195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 228.55200195 27.3220005 Tm [(activat)1(ed)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 267.70300293 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 10.51200008 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 15.01200008 42.92200089 Tm [(cold)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 33.39899826 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 37.89899826 42.92200089 Tm [(temperat)1(ure)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 91.49900055 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 95.99900055 42.92200089 Tm [(below)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 122.0759964 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 126.5759964 42.92200089 Tm [(25)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 137.13200378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 141.63200378 42.92200089 Tm [(degrees)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 176.06799316 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 180.56799316 42.92200089 Tm [(Celsiu)-1(s.)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 212.52900696 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 217.02900696 42.92200089 Tm [(Activa)1(ted)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 257.53799438 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 262.03799438 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 272.54998779 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ic)-1(ilin,)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 21.80599976 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 26.30599976 58.52199936 Tm [(eu)-1(calypt)1(ol,)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 72.98899841 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 77.48899841 58.52199936 Tm [(men)-1(t)1(hol,)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 115.7519989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 120.2519989 58.52199936 Tm [(cold)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 138.63900757 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 143.13900757 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 159.41600037 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 163.91600037 58.52199936 Tm [(mod)1(u)-1(la)1(tion)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 213.75900269 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 218.25900269 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 227.10099792 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 231.60099792 58.52199936 Tm [(intra)1(c)-1(ell)-1(ul)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ar)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 8.41100025 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 12.91100025 74.12200165 Tm [(pH.)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 27.7859993 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 32.2859993 74.12200165 Tm [(Involved)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 68.90599823 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 73.40599823 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 81.34700012 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 85.84700012 74.12200165 Tm [(men)-1(t)1(hol)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 121.94400024 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 126.44400024 74.12200165 Tm [(sensation.)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 169.58500671 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 174.08500671 74.12200165 Tm [(Permeable)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 219.897995 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 224.397995 74.12200165 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 236.67599487 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 241.17599487 74.12200165 Tm [(monova)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(len)-1(t)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 16.39999962 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 20.89999962 89.72200012 Tm [(cations)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 51.56900024 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 56.06900024 89.72200012 Tm [(sod)1(iu)-1(m,)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 90.2539978 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 94.7539978 89.72200012 Tm [(po)1(tass)1(i)-1(um,)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 141.42399597 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 145.92399597 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 162.20100403 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 166.70100403 89.72200012 Tm [(ce)-1(sium)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 196.86099243 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 201.36099243 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 217.63800049 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 222.13800049 89.72200012 Tm [(diva)1(l)-1(ent)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 256.38900757 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 260.88900757 89.72200012 Tm [(cati)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(on)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 11.26799965 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 15.76799965 105.3219986 Tm [(calc)-1(ium.)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 50.70500183 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 55.20500183 105.3219986 Tm [(Te)-1(mp)1(e)-1(ra)1(ture)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 110.61100006 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 115.11100006 105.3219986 Tm [(sensin)-1(g)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 147.79299927 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 152.29299927 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 158.85400391 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 163.35400391 105.3219986 Tm [(tig)1(htly)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 190.91200256 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 195.41200256 105.3219986 Tm [(link)-1(ed)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 221.51100159 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 226.01100159 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 235.08599854 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 239.58599854 105.3219986 Tm [(volt)1(age-)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(dependen)-1(t)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 47.02600098 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 51.52600098 120.92199707 Tm [(ga)1(ting.)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 81.47499847 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 85.97499847 120.92199707 Tm [(Activa)1(ted)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 126.48400116 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 130.98399353 120.92199707 Tm [(upon)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 153.54600525 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 158.04600525 120.92199707 Tm [(depo)1(l)-1(a)1(rizat)1(ion,)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 222.16200256 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 226.66200256 120.92199707 Tm [(changes)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 262.26599121 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 266.76599121 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 274.70700073 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(temperat)1(ure)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 53.59999847 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 58.09999847 136.52200317 Tm [(resulting)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 95.8010025 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 100.3010025 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 108.24199677 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 112.74199677 136.52200317 Tm [(gr)1(aded)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 143.52999878 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 148.02999878 136.52200317 Tm [(shif)1(ts)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 170.77200317 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 175.27200317 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 184.11399841 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 188.61399841 136.52200317 Tm [(its)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 198.52799988 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 203.02799988 136.52200317 Tm [(volt)1(age-d)1(e)-1(p)1(e)-1(nd)] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(en)-1(t)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 14.00500011 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 18.50499916 152.12199402 Tm [(activat)1(ion)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 60.45500183 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 64.95500183 152.12199402 Tm [(cu)-1(rv)1(e)-1(s.)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 94.61399841 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 99.11399841 152.12199402 Tm [(The)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 114.92099762 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 119.42099762 152.12199402 Tm [(che)-1(mical)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 157.29299927 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 161.79299927 152.12199402 Tm [(ag)1(onist)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 193.70599365 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 198.20599365 152.12199402 Tm [(men)-1(t)1(hol)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 234.30299377 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 238.80299377 152.12199402 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(s)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 4.16599989 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 8.66600037 167.72200012 Tm [(as)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 17.80699921 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 22.30699921 167.72200012 Tm [(a)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 27.28199959 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 31.78199959 167.72200012 Tm [(ga)1(ting)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 59.56399918 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 64.06400299 167.72200012 Tm [(mod)1(i)-1(f)1(ie)-1(r,)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 102.59500122 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 107.09500122 167.72200012 Tm [(shif)1(ting)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 139.36799622 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 143.86799622 167.72200012 Tm [(activat)1(ion)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 185.81799316 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 190.31799316 167.72200012 Tm [(cu)-1(rv)1(e)-1(s)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 217.80999756 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 222.30999756 167.72200012 Tm [(to)1(war)1(ds)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 256.82501221 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 261.32501221 167.72200012 Tm [(ph)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 0 183.32200623 Tm [(ysiological)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 45.19800186 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 49.69800186 183.32200623 Tm [(membrane)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 96.48200226 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 100.98200226 183.32200623 Tm [(po)1(ten)-1(t)1(ials.)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 145.90699768 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 150.40699768 183.32200623 Tm [(Te)-1(mp)1(e)-1(ra)1(ture)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 205.81300354 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 210.31300354 183.32200623 Tm [(sensitivity)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 252.67599487 183.32200623 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 257.17599487 183.32200623 Tm [(aris)] TJ ET EMC Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 187.94999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 138.30000305 0.75 m 138.30000305 187.94999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 187.94999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 188.32499695 m 423.17498779 188.32499695 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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