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234.27600098 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 29 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<000C>] TJ ET EMC /P <</MCID 30 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(MTO2;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 71.17700195 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 73.5510025 12.82499981 Tm [(MTU1;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 102.51300049 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 104.88700104 12.82499981 Tm [(TRMT)-1(;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 132.60800171 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 134.98199463 12.82499981 Tm [(LC)-1(A)1(L)-1(3)1(;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 163.61599731 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 165.99000549 12.82499981 Tm [(TRMT)-1(1)1(;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 199.03300476 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 201.40699768 12.82499981 Tm [(TRNT1)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 229.44099426 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0010>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 51 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(TRMU)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 68.53199768 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 53 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 54 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(   )] TJ ET EMC /P <</Lang (zh-CN) /MCID 55 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [<0012>] TJ ET EMC /P <</MCID 56 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 36.75 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 59 >> BDC BT 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TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 39.56000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 41.93399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 42 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 71.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 84 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 74 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <</MCID 75 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 101.36000061 12.82499981 Tm [(Do)-1(g)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 118.2990036 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 120.67299652 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 123.29299927 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 125.66699982 12.82499981 Tm [(Mon)-1(k)1(ey)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 160.44799805 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 162.82200623 12.82499981 Tm [(,)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 165.44200134 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 167.81599426 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 197.17799377 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 92 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<002000210022000F>] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 96 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230005>] TJ ET EMC /P <</MCID 97 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 99 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0024>] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 101 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0025>] TJ ET EMC /P <</MCID 102 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 103 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0026>] TJ ET EMC /P <</MCID 104 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 110 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800220027>] TJ ET EMC /P <</MCID 111 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 118 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 119 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 120 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 121 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 122 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 140.17500305 141.1499939 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 123 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 53.27999878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 57.77999878 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 79.29599762 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 83.79599762 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 119.71299744 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 124.21299744 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 129.18800354 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 133.68800354 11.72200012 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(rial)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 193.8710022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 198.3710022 11.72200012 Tm [(tR)1(NA-mo)1(difying)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 269.03100586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(en)-1(z)1(y)-1(me.)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 35.54700089 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 40.04700089 27.3220005 Tm [(The)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 55.85400009 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 60.35400009 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 97.86100006 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 102.36100006 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 133.66799927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 138.16799927 27.3220005 Tm [(cata)1(l)-1(yzes)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 176.83999634 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 181.33999634 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 195.34100342 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 199.84100342 27.3220005 Tm [(2-th)1(iolatio)1(n)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 250.40899658 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 254.90899658 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 263.75100708 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 268.25100708 27.3220005 Tm [(u)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ridine)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 24.63599968 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 29.13599968 42.92200089 Tm [(on)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 40.40399933 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 44.90399933 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 58.90499878 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 63.40499878 42.92200089 Tm [(wo)1(bble)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 95.23000336 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 99.73000336 42.92200089 Tm [(po)1(sitions)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 138.94200134 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 143.44200134 42.92200089 Tm [(of)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 152.28399658 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 156.78399658 42.92200089 Tm [(tR)1(NA\(Lys\),)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 201.38800049 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 205.88800049 42.92200089 Tm [(tR)1(NA\(Glu\),)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 251.57800293 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 256.07800293 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 272.35501099 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(tR)1(NA\(Gln\),)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 45.68999863 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 50.18999863 58.52199936 Tm [(resulting)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 87.89099884 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 92.39099884 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 100.33200073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 104.83200073 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 118.83300018 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 123.33300018 58.52199936 Tm [(fo)1(rmatio)1(n)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 166.03500366 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 170.53500366 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 179.3769989 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 183.8769989 58.52199936 Tm [(5-ta)1(u)-1(r)1(in)-1(o)1(me)-1(t)1(hyl)-1(-)1(2)-1(-)1(t)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(hiourid)1(in)-1(e)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 43.84000015 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 48.34000015 74.12200165 Tm [(moieties.)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 87.18299866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 91.68299866 74.12200165 Tm [(Mutat)1(ions)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 135.53199768 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 140.03199768 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 147.9730072 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 152.4730072 74.12200165 Tm [(th)1(is)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 167.92900085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 172.42900085 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 193.94500732 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 198.44500732 74.12200165 Tm [(may)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 216.61599731 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 221.11599731 74.12200165 Tm [(cause)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 245.42199707 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 249.92199707 74.12200165 Tm [(tr)1(ansi)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(en)-1(t)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 14.00500011 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 18.50499916 89.72200012 Tm [(infantile)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 53.33599854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 57.83599854 89.72200012 Tm [(live)-1(r)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 75.89299774 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 80.39299774 89.72200012 Tm [(fa)1(i)-1(lure.)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 109.53299713 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 114.03299713 89.72200012 Tm [(Polymorp)1(hisms)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 180.46099854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 184.96099854 89.72200012 Tm [(in)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 192.9019928 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 197.4019928 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 212.85800171 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 217.35800171 89.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 238.87399292 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 243.37399292 89.72200012 Tm [(may)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 261.54501343 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 266.04501343 89.72200012 Tm [(al)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(so)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 9.88799953 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 14.38799953 105.3219986 Tm [(influe)-1(nce)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 53.66199875 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 58.16199875 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 72.16300201 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 76.66300201 105.3219986 Tm [(seve)-1(r)1(i)-1(t)1(y)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 109.71399689 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 114.21399689 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 123.05599976 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 127.55599976 105.3219986 Tm [(deaf)1(n)-1(ess)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 165.4980011 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 169.9980011 105.3219986 Tm [(cause)-1(d)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 200.06100464 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 204.56100464 105.3219986 Tm [(by)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 215.07299805 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 219.57299805 105.3219986 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(ri)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(al)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 7.36999989 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 11.86999989 120.92199707 Tm [(12)-1(S)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 27.62000084 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 32.11999893 120.92199707 Tm [(ribo)1(somal)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 75.11199951 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 79.61199951 120.92199707 Tm [(RNA)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 99.13700104 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 103.63700104 120.92199707 Tm [(mutat)1(ions.)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 149.29200745 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 153.79200745 120.92199707 Tm [(Alt)1(e)-1(rna)1(tive)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 200.51499939 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 205.01499939 120.92199707 Tm [(splicin)-1(g)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 237.92999268 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 242.42999268 120.92199707 Tm [(results)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 270.59899902 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(in)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 7.94099998 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 12.44099998 136.52200317 Tm [(multiple)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 47.81299973 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 52.31299973 136.52200317 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 93.23500061 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 97.73500061 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s.)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 133.47099304 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 262 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 263 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 264 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB,)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IF)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 28.89900017 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 268 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 273 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 274 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TRMU)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 26.54700089 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 173.8500061 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 276 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 277 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 278 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Fusion)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(TRMU)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 142.89300537 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 190.19999695 cm q /GS2 gs 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 288 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 291 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 292 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(tR)1(NA)] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 22.87800026 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 27.37800026 11.72200012 Tm [(5-methylaminomethyl-2-t)1(hiouridylat)1(e)] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 190.60800171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 195.10800171 11.72200012 Tm [(methyltr)1(ansferase)] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 272.08700562 11.72200012 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 206.55001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 0.75 m 139.80000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 141.8999939 m 139.80000305 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 158.25 m 139.80000305 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 174.6000061 m 139.80000305 190.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 190.95001221 m 139.80000305 206.55001831 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 206.55001831 l S Q q /GS1 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