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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm q 1 0 0 1 66 0 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 0 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 71.76399994 23.67700005 Tm 0 Tr [(TRIM38)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 147.93699646 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 258.37701416 23.67700005 Tm 0 Tr [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 291.37701416 23.67700005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000A000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 60.56000137 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.68499756 12.82499981 Tm [(TRIM38)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 130.39399719 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 182.89399719 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.14399719 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000E000B000C000D>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.18399811 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TRIM38)] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.81800079 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.19200134 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.96400452 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.33799744 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.65899658 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.03300476 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.82899475 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(RN)1(F)-1(15;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.75700378 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.1309967 12.82499981 Tm [(RORET)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.72899628 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TRIM38)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.08399963 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0012>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001300140015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<00160017>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<00180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001A>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.36599731 12.82499981 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.36000061 12.82499981 Tm [(Do)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.2990036 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.67299652 12.82499981 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.29299927 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.66699982 12.82499981 Tm [(Rat)] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.91499329 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.28900146 12.82499981 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.90899658 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.28300476 12.82499981 Tm [(Mon)-1(k)1(ey)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.06399536 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.43800354 12.82499981 Tm [(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.05799866 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.43200684 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.79400635 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<002000210022000F>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00230005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0025>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0026>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800220027>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm [(:)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.81000137 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 18 Tf 1 0 0 -1 42 20.17499924 Tm 1 Tr 0.51428574 w /GS3 gs 0 G [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 94.34999847 l 0.375 94.34999847 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 50.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 57.29199982 50.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 94.34999847 l 140.17500305 94.34999847 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 95.34999847 l -0.625 95.34999847 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(tr)1(i)-1(p)1(art)1(ite)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.82800293 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.32800293 11.72200012 Tm [(mot)1(if)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.35099792 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.85099792 11.72200012 Tm [(\(TRIM\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.33599854 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.24799919 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.7480011 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.55500031 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.05500031 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.56199646 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.06199646 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.3690033 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.8690033 27.3220005 Tm [(contains)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.08399963 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.58399963 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.55900574 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.05900574 27.3220005 Tm [(RING)1(-type)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.45500183 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.95500183 27.3220005 Tm [(zinc)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.83399963 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.33399963 27.3220005 Tm [(finge)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(r,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.60300016 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.10299969 42.92200089 Tm [(B)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.75 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.25 42.92200089 Tm [(bo)1(x-t)1(y)-1(p)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.14599991 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.64599991 42.92200089 Tm [(zinc)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.52500153 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.02500153 42.92200089 Tm [(finger)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.38600159 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.88600159 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.16299438 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.66299438 42.92200089 Tm [(SPRY)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.67100525 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 162.17100525 42.92200089 Tm [(do)1(main.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.16499329 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.66499329 42.92200089 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.47200012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.97200012 42.92200089 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.7130127 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.2130127 42.92200089 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.05499268 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.45600033 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 19.95599937 58.52199936 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.26300049 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.76300049 58.52199936 Tm [(ha)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.44499969 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.94499969 58.52199936 Tm [(not)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.56600189 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.06600189 58.52199936 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.57299805 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.07299805 58.52199936 Tm [(identified.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.16999817 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.66999817 58.52199936 Tm [(A)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.00300598 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.50300598 58.52199936 Tm [(pseudog)1(e)-1(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.06399536 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.56399536 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.40600586 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.90600586 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.36199951 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.51600075 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.01600075 74.12200165 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.57699966 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.07699966 74.12200165 Tm [(located)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.89800262 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.39800262 74.12200165 Tm [(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.66600037 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.16600037 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.16699982 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.66699982 74.12200165 Tm [(long)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.08599854 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.58599854 74.12200165 Tm [(arm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.42999268 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.92999268 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.77200317 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.27200317 74.12200165 Tm [(chromos)1(ome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.06700134 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.56700134 74.12200165 Tm [(4.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.01100159 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.51100159 74.12200165 Tm [([pr)1(ovide)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.75699997 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.25699997 89.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.7689991 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.2689991 89.72200012 Tm [(RefSeq,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.59500122 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.09500122 89.72200012 Tm [(Jul)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.59999847 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.09999847 89.72200012 Tm [(20)-1(12)-1(].)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.38400269 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 94.34999847 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.97200012 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.47200012 11.72200012 Tm [(IHC,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.26499939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.76499939 11.72200012 Tm [(IF)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.19200134 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 110.69999695 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(TRIM38)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.02899933 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 127.05000305 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Immunogen:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 57.89400101 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Fusion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 28.15600014 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.65599823 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.96300125 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.46299744 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.30500031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.80500031 11.72200012 Tm [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.84600067 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 116.34600067 11.72200012 Tm [(TRIM38)] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.375 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 143.3999939 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(tr)1(i)-1(p)1(art)1(ite)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.55099869 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.05099869 11.72200012 Tm [(mot)1(if)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.0739975 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.5739975 11.72200012 Tm [(containing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.32099915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.82099915 11.72200012 Tm [(38)] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.3769989 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.8769989 11.72200012 Tm [(\(TRIM38)-1(\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.91799927 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 159.75 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(RNF15)-1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.69599915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.19599915 11.72200012 Tm [(RORE)1(T)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.38899994 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 176.1000061 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Sw)1(iss)1(P)-1(r)1(o)-1(t:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 46.56900024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(O00)-1(63)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 192.44999695 cm q 1 g 0.375 0.75 m 139.42500305 0.75 l 139.42500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 140.42500305 -0.25 l 140.42500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(IH)-1(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.47100067 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.97100067 11.72200012 Tm [(positive)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.80799866 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.30799866 11.72200012 Tm [(control:)] TJ ET EMC /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 96.39399719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 140.17500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 140.17500305 16.35000038 l h f* Q q 1 0 0 1 139.80000305 0 cm -0.625 -0.25 m 283.625 -0.25 l 283.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADF 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.04100037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.54100037 11.72200012 Tm [(ki)-1(d)1(ne)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.00899887 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.50900269 11.72200012 Tm [(tiss)1(u)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.24099731 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 208.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 0.75 m 139.80000305 94.34999847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 95.09999847 m 139.80000305 110.69999695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 111.44999695 m 139.80000305 127.04999542 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 127.79999542 m 139.80000305 143.3999939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 144.1499939 m 139.80000305 159.75 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 160.5 m 139.80000305 176.1000061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 176.8500061 m 139.80000305 192.45001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 139.80000305 193.20001221 m 139.80000305 208.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 208.80001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 94.72499847 m 422.42498779 94.72499847 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 111.07499695 m 422.42498779 111.07499695 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 127.42499542 m 422.42498779 127.42499542 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 143.7749939 m 422.42498779 143.7749939 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 160.125 m 422.42498779 160.125 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 176.4750061 m 422.42498779 176.4750061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 192.82501221 m 422.42498779 192.82501221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 209.17501831 m 423.17498779 209.17501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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