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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 98.48500061 23.67700005 Tm 0 g [(CA6)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 140.11099243 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 316.81500244 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(CA6)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 79.9960022 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 85.2460022 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 169.2460022 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(CA6)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 79.9960022 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 82.37000275 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 115.5719986 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 117.94599915 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 177.92599487 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 180.30000305 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 214.77400208 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(car)1(b)-1(on)-1(ic)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 99.55000305 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 101.9240036 12.82499981 Tm [(anh)-1(y)1(d)-1(r)1(as)-1(e)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 146.2769928 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 148.65100098 12.82499981 Tm [(6;)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 156.78199768 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 159.15600586 12.82499981 Tm [(CA-VI;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 185.45700073 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 187.83099365 12.82499981 Tm [(GU)1(S)-1(TIN)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 220.55599976 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 33 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <</MCID 34 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 35 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <</MCID 36 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 37 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <</MCID 38 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 39 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <</MCID 40 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 139.85800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 42 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <</MCID 43 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 44 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 45 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 46 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 208.89500427 cm /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 30.76399994 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001A>-4<001B>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 21.08399963 30.76399994 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 50 >> BDC BT 1 0 0 -1 0 48.43599701 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 272.71200562 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 51 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 52 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 53 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 54 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 55 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 56 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 57 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(18-17)1(9)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 226.41799927 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 228.45300293 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 251.4940033 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 253.52900696 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 271.95999146 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 273.99499512 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 281.48800659 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 283.52301025 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 309.20901489 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 311.24398804 12.04500008 Tm [(CA6)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 325.81201172 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 301.65100098 cm /P <</MCID 79 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 329.58999634 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABE 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 2 Tr /GS2 gs 0 g 0.30000001 w [<001C>-4<001D>-4<001E>-4<001F>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAABB 10.5 Tf 1 0 0 -1 42.16799927 12.82499981 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 357.5289917 cm /P <</MCID 82 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 385.46798706 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 83 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 86 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 87 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(carbo)1(n)-1(ic)] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 36.84799957 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 41.34799957 11.72200012 Tm [(anhydr)1(ase)] TJ ET EMC /P <</MCID 90 >> BDC BT 1 0 0 -1 85.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC BT 1 0 0 -1 90.11399841 11.72200012 Tm [(6)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 95.39199829 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 93 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 94 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(CA-)1(VI;)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 27.14500046 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 31.64500046 11.72200012 Tm [(GU)1(ST)-1(IN)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 65.3730011 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 99 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 100 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 101 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(P23)-1(28)-1(0)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 31.89599991 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 103 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 107 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(34)-1(35)-1(0)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 109 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 110 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 127 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 130 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 135 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 136 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 121.72499847 16.35000038 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 137 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 120.97499847 0.75 l 120.97499847 63.15000153 l 0.375 63.15000153 l h f* Q q -0.625 -0.25 m 121.97499847 -0.25 l 121.97499847 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 149 >> BDC BT /FAAACF 9 Tf 1 0 0 -1 0 35.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 150 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 57.29199982 35.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 121.72499847 0.75 m 426.17501831 0.75 l 426.17501831 63.15000153 l 121.72499847 63.15000153 l h f* Q q 1 0 0 1 121.34999847 0 cm -0.625 -0.25 m 305.82501221 -0.25 l 305.82501221 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 151 >> BDC BT /FAAACI 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(one)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 186.53999329 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 191.03999329 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 199.88200378 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 204.38200378 11.72200012 Tm [(seve)-1(r)1(al)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 234.29100037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 238.79100037 11.72200012 Tm [(isoz)1(y)-1(mes)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 277.96798706 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 282.46798706 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 291.30999756 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(carbo)1(n)-1(ic)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 36.84799957 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 41.34799957 27.3220005 Tm [(anhydr)1(ase.)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 87.78099823 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 92.28099823 27.3220005 Tm [(This)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 109.54299927 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 114.04299927 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 145.3500061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 149.8500061 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 156.41099548 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 160.91099548 27.3220005 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 186.60099792 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 191.10099792 27.3220005 Tm [(only)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 209.5269928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 214.0269928 27.3220005 Tm [(in)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 221.96800232 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 226.46800232 27.3220005 Tm [(saliva)1(ry)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 258.29800415 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 262.79800415 27.3220005 Tm [(gla)1(n)-1(d)1(s)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 291.39300537 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 16.27700043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 20.77700043 42.92200089 Tm [(saliva)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 44.40599823 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 48.90599823 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 65.18299866 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 69.68299866 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 100.98999786 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 105.48999786 42.92200089 Tm [(may)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 123.66100311 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 128.16099548 42.92200089 Tm [(play)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 146.04200745 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 150.54200745 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 155.51699829 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 160.01699829 42.92200089 Tm [(role)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 176.67700195 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 181.17700195 42.92200089 Tm [(in)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 189.11799622 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 193.61799622 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 207.6190033 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 212.1190033 42.92200089 Tm [(reve)-1(r)1(sible)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 253.74000549 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 258.23999023 42.92200089 Tm [(hydra)1(tat)1(i)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(on)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 11.26799965 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 15.76799965 58.52199936 Tm [(of)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 24.61000061 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 29.11000061 58.52199936 Tm [(carbo)1(n)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 59.04999924 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 63.54999924 58.52199936 Tm [(diox)1(ide)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 95.24299622 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 99.74299622 58.52199936 Tm [(th)1(ough)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 131.20300293 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 135.70300293 58.52199936 Tm [(its)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 145.61700439 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 150.11700439 58.52199936 Tm [(func)-1(t)1(ion)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 185.85800171 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 190.35800171 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 198.29899597 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 202.79899597 58.52199936 Tm [(saliva)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 226.42799377 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 230.92799377 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 237.48899841 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 241.98899841 58.52199936 Tm [(unk)-1(now)1(n)-1(.)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 284.06698608 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 0.75 m 121.34999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 17.10000038 m 121.34999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 33.45000076 m 121.34999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 49.80000305 m 121.34999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 66.15000153 m 121.34999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 82.5 m 121.34999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 98.84999847 m 121.34999847 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 121.34999847 115.19999695 m 121.34999847 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17501831 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17501831 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17501831 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17501831 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17501831 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17501831 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17501831 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 177.9750061 m 426.92501831 177.9750061 l S Q Q q 1 0 0 1 0 563.81799316 cm /P <</MCID 240 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 591.75701904 cm Q Q 1 0 0 -1 0 841.90002441 cm 
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