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12.82499981 Tm 0 g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(TNFRS)-1(F8)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 137.14100647 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 189.64100647 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 194.89100647 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TN)1(F)-1(RSF)-1(8)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 121.12400055 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 123.4980011 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 152.27000427 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 154.64399719 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 204.96499634 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 207.33900452 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 245.13499451 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TNF)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 79.71900177 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 82.09300232 12.82499981 Tm [(re)1(ceptor)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 118.87400055 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 121.2480011 12.82499981 Tm [(su)-1(pe)1(rfami)-1(ly)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 171.46699524 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 173.84100342 12.82499981 Tm [(me)1(mb)-1(e)1(r)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 210.24200439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 212.61599731 12.82499981 Tm [(8;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 220.74699402 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 223.1210022 12.82499981 Tm [(CD30;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 248.63299561 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 251.00700378 12.82499981 Tm [(Ki-1;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 270.21798706 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 272.5920105 12.82499981 Tm [(D1S)-1(1)1(66E)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 310.29000854 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 41 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 42 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 45 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 46 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0015>] TJ ET EMC /P <</MCID 47 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001C>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 59 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 61 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0005>] TJ ET EMC /P <</MCID 62 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TNFRS)-1(F8)] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 100.39099884 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0023>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 80 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 81 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 86 >> BDC q 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 87 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 88 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 413.39001465 cm q 1 g 0.375 0.75 m 151.0249939 0.75 l 151.0249939 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 152.0249939 -0.25 l 152.0249939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 89 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 151.7749939 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 151.7749939 172.3500061 l h f* Q q 1 0 0 1 151.3999939 0 cm -0.625 -0.25 m 272.0249939 -0.25 l 272.0249939 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 91 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(The)] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(T)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(NF-rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 52.41400146 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 56.91400146 27.3220005 Tm [(superfa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 109.16500092 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 113.66500092 27.3220005 Tm [(This)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 130.92700195 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 135.42700195 27.3220005 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 171.84899902 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 176.34899902 27.3220005 Tm [(is)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 182.91000366 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 187.41000366 27.3220005 Tm [(expressed)] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 230.56399536 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 235.06399536 27.3220005 Tm [(by)] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 245.57600403 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 250.07600403 27.3220005 Tm [(act)] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ivat)1(e)-1(d)1(,)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 28.47699928 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 32.97700119 42.92200089 Tm [(but)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 47.62400055 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 52.12400055 42.92200089 Tm [(not)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 66.74500275 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 71.24500275 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 81.75700378 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 86.25700378 42.92200089 Tm [(resting,)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 118.18299866 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 122.68299866 42.92200089 Tm [(T)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 127.84200287 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 132.34199524 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 148.6190033 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 153.1190033 42.92200089 Tm [(B)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 158.76600647 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 163.26600647 42.92200089 Tm [(ce)-1(lls.)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 184.00799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 188.50799561 42.92200089 Tm [(TRAF2)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 215.93400574 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 220.43400574 42.92200089 Tm [(and)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 236.71099854 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 241.21099854 42.92200089 Tm [(TRAF)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(5)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 5.27799988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 9.77799988 58.52199936 Tm [(can)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 24.81200027 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 29.31200027 58.52199936 Tm [(interact)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 61.99000168 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 66.48999786 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 84.88600159 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 89.38600159 58.52199936 Tm [(th)1(is)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 104.84200287 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 109.34200287 58.52199936 Tm [(rec)-1(ept)1(or,)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 147.92999268 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 152.42999268 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 168.70700073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 173.20700073 58.52199936 Tm [(mediat)1(e)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 208.33200073 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 212.83200073 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 226.83299255 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 231.33299255 58.52199936 Tm [(signal)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 256.56600952 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(tr)1(ansduc)-1(t)1(ion)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 54.30799866 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 58.80799866 74.12200165 Tm [(th)1(at)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 76.02999878 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 80.52999878 74.12200165 Tm [(leads)] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 102.92900085 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 107.42900085 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 116.5039978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 121.0039978 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 135.00500488 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 139.50500488 74.12200165 Tm [(activat)1(ion)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 181.45500183 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 185.95500183 74.12200165 Tm [(of)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 194.79699707 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 199.29699707 74.12200165 Tm [(NF-kapp)1(aB)-1(.)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 249.44700623 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 253.94700623 74.12200165 Tm [(T)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(his)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 12.10299969 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 16.60300064 89.72200012 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 53.02500153 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 57.52500153 89.72200012 Tm [(is)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 64.08599854 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 68.58599854 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 73.56099701 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 78.06099701 89.72200012 Tm [(po)1(sitive)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 111.66999817 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 116.16999817 89.72200012 Tm [(regulat)1(or)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 155.89700317 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 160.39700317 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 169.23899841 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 173.73899841 89.72200012 Tm [(ap)1(opt)1(osis,)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 217.8999939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 222.3999939 89.72200012 Tm [(and)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 238.67700195 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 243.17700195 89.72200012 Tm [(also)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 260.43399048 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 14.68200016 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 19.18199921 105.3219986 Tm [(been)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 40.68899918 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 45.18899918 105.3219986 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 73.26999664 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 77.76999664 105.3219986 Tm [(to)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 86.84500122 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 91.34500122 105.3219986 Tm [(limit)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 110.31600189 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 114.81600189 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 128.81700134 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 133.31700134 105.3219986 Tm [(pro)1(life)-1(r)1(ative)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 185.22999573 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 189.72999573 105.3219986 Tm [(po)1(ten)-1(t)1(ial)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 228.32299805 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 232.82299805 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 241.66499329 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 246.16499329 105.3219986 Tm [(aut)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(oreactive)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 39.33100128 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 43.83100128 120.92199707 Tm [(CD8)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 61.98500061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 66.48500061 120.92199707 Tm [(effec)-1(t)1(or)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 99.96299744 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 104.46299744 120.92199707 Tm [(T)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 109.62200165 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 114.12200165 120.92199707 Tm [(ce)-1(lls)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 132.69799805 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 137.19799805 120.92199707 Tm [(and)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 153.4750061 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 157.9750061 120.92199707 Tm [(pro)1(tec)-1(t)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 189.20700073 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 193.70700073 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 207.70799255 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 212.20799255 120.92199707 Tm [(bo)1(dy)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 234.19799805 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 238.69799805 120.92199707 Tm [(ag)1(ain)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(st)] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 7.51900005 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 12.01900005 136.52200317 Tm [(auto)1(immu)-1(nit)1(y)-1(.)] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 74.64499664 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 79.14499664 136.52200317 Tm [(Two)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 97.13200378 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 101.63200378 136.52200317 Tm [(alt)1(e)-1(rnat)1(ive)-1(ly)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 154.15499878 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 158.65499878 136.52200317 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 188.73599243 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 193.23599243 136.52200317 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 234.15800476 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 238.65800476 136.52200317 Tm [(var)1(i)-1(a)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(nts)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 13.06499958 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 17.56500053 152.12199402 Tm [(of)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 26.40699959 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 30.90699959 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 46.36299896 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 50.86299896 152.12199402 Tm [(gene)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 72.3789978 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 76.8789978 152.12199402 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 117.22100067 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 121.72100067 152.12199402 Tm [(dist)1(in)-1(ct)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 153.19900513 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 157.69900513 152.12199402 Tm [(isof)1(orms)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 194.85899353 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 199.35899353 152.12199402 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 219.70599365 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 224.20599365 152.12199402 Tm [(been)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 245.71299744 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 250.21299744 152.12199402 Tm [(re)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(po)1(rted.)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 31.28899956 167.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 172.3500061 cm q 1 g 0.375 0.75 m 151.0249939 0.75 l 151.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 152.0249939 -0.25 l 152.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 281 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 282 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 151.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 151.7749939 16.35000038 l h f* Q q 1 0 0 1 151.3999939 0 cm -0.625 -0.25 m 272.0249939 -0.25 l 272.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 283 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 188.69999695 cm q 1 g 0.375 0.75 m 151.0249939 0.75 l 151.0249939 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 152.0249939 -0.25 l 152.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 285 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 290 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 g 151.7749939 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 151.7749939 16.35000038 l h f* Q q 1 0 0 1 151.3999939 0 cm -0.625 -0.25 m 272.0249939 -0.25 l 272.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 291 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm 0.13333334 g [(TNFRSF)-1(8)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 38.38600159 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 205.05001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 151.3999939 0.75 m 151.3999939 172.3500061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 151.3999939 173.1000061 m 151.3999939 188.70001221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 151.3999939 189.45001221 m 151.3999939 205.05001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 205.05001831 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 172.7250061 m 422.42498779 172.7250061 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 189.07501221 m 422.42498779 189.07501221 l S Q q 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 205.42501831 m 423.17498779 205.42501831 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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