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1 0 0 -1 0 841.90002441 cm /Artifact <</Attached [/Top ] /BBox [90 695.85003662 505.29998779 799.35003662] /Type /Pagination >> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [(  )] TJ ET q 1 0 0 1 9 1 cm q 270.1000061 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <</MCID 0 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 75.1210022 23.67700005 Tm 0 g [(C12orf10)] TJ ET EMC /P <</Lang (zh-CN) /MCID 1 >> BDC BT /FAAABE 22 Tf 1 0 0 -1 163.4750061 23.67700005 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <</MCID 2 >> BDC BT /FAAABB 22 Tf 1 0 0 -1 340.1789856 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <</Lang (zh-CN) /MCID 3 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <</MCID 4 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 5 >> BDC BT 1 0 0 -1 63 12.82499981 Tm [(C12orf10)] TJ ET EMC /P <</MCID 6 >> BDC BT 1 0 0 -1 102.28800201 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 7 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 107.53800201 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <</MCID 8 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 191.53799438 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 9 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <</MCID 10 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 11 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(C12orf10)] TJ ET EMC /P <</MCID 12 >> BDC BT 1 0 0 -1 102.28800201 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 104.66200256 12.82499981 Tm [(Antigen)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 137.86399841 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 140.23800659 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 200.21800232 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 202.59199524 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 237.06599426 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 19 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <</MCID 20 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000D000F>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(chromos)-1(ome)] TJ ET EMC /P <</MCID 24 >> BDC BT 1 0 0 -1 119.33499908 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 121.70899963 12.82499981 Tm [(12)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 132.35299683 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 134.727005 12.82499981 Tm [(op)-1(e)1(n)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 156.52200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 158.89599609 12.82499981 Tm [(re)1(ad)-1(ing)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 191.19599915 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 193.57000732 12.82499981 Tm [(frame)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 219.07699585 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 221.45100403 12.82499981 Tm [(10;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 234.90400696 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 237.27799988 12.82499981 Tm [(MYG;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 260.80599976 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 263.17999268 12.82499981 Tm [(MYG1;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 292.0289917 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 294.40301514 12.82499981 Tm [(Gamm1)1(;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 330.9630127 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 333.33700562 12.82499981 Tm [(MST)-1(02)1(4;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 371.02999878 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 373.4039917 12.82499981 Tm [(MST)-1(P)1(024)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 413.71200562 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012001300140011000F>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000F>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180005>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0019000A>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 58 >> BDC BT 1 0 0 -1 134.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</MCID 59 >> BDC q /GS2 gs 1 g 0 6.59399986 m 21 6.59399986 l 21 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<00030004>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 21 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 261.29501343 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <</MCID 62 >> BDC BT /FAAAAH 9 Tf 1 0 0 -1 0 12.04500008 Tm /GS2 gs 0 g [(Fu)-1(sio)-1(n)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 23.92399979 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 25.95899963 12.04500008 Tm [(protein)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 52.85800171 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 66 >> BDC BT 1 0 0 -1 54.89300156 12.04500008 Tm [(corr)1(esp)-1(ond)-1(in)-1(g)] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 107.68000031 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 109.71499634 12.04500008 Tm [(to)] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 117.47599792 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 119.51100159 12.04500008 Tm [(a)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 123.8219986 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 125.85700226 12.04500008 Tm [(re)1(gio)-1(n)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 149.24899292 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 151.28399658 12.04500008 Tm [(derive)1(d)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 178.96499634 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 181 12.04500008 Tm [(from)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 198.82000732 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 200.85499573 12.04500008 Tm [(156-3)1(76)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 230.97999573 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 233.01499939 12.04500008 Tm [(amin)-1(o)] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 256.05599976 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 258.09100342 12.04500008 Tm [(acid)-1(s)] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 276.52200317 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 278.55700684 12.04500008 Tm [(of)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 286.04998779 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 288.08499146 12.04500008 Tm [(hu)-1(man)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 313.77099609 12.04500008 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 315.80599976 12.04500008 Tm [(C12orf10)] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 349.48098755 12.04500008 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q /GS2 gs 1 g -1.45000005 290.23400879 m 416.75 290.23400879 l 416.75 321.434021 l -1.45000005 321.434021 l h f* Q q /GS2 gs 1 g -1.45000005 321.43399048 m 416.75 321.43399048 l 416.75 352.63400269 l -1.45000005 352.63400269 l h f* Q q 1 0 0 1 0 290.23400879 cm /P <</MCID 90 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 0 20.17499924 Tm [( )] TJ ET EMC /P <</MCID 91 >> BDC q /GS2 gs 1 g 0 37.79399872 m 42 37.79399872 l 42 55.80500031 l 0 55.80500031 l h f* Q EMC /P <</Lang (zh-CN) /MCID 92 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 51.375 Tm /GS2 gs 0.13333334 g [<0005000600070008>] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 51.375 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 352.63400269 cm /P <</MCID 94 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 380.57299805 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 95 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 98 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 99 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(chromos)1(ome)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 56.79499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 61.29499817 11.72200012 Tm [(12)] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 71.85099792 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 76.35099792 11.72200012 Tm [(op)1(e)-1(n)] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 98.47299957 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 102.97299957 11.72200012 Tm [(reading)] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 135.94500732 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 140.44500732 11.72200012 Tm [(fra)1(me)] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 165.51600647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 170.01600647 11.72200012 Tm [(10)] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 180.57200623 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 111 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <</MCID 112 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 113 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(MYG)1(;)] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 23.08399963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 27.58399963 11.72200012 Tm [(MYG)1(1)-1(;)] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 55.94599915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 60.44599915 11.72200012 Tm [(Ga)1(mm1)-1(;)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 96.4240036 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 100.9240036 11.72200012 Tm [(MST0)-1(24)-1(;)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 138.07099915 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 142.57099915 11.72200012 Tm [(MSTP0)-1(24)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 183.05799866 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 123 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <</MCID 124 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 125 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9H)-1(B0)-1(7)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 35.77600098 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 127 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <</MCID 130 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 131 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(28)-1(90)-1(4)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 133 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <</MCID 134 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 135 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 151 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <</MCID 154 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 155 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 159 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <</MCID 160 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 109.77500153 16.35000038 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 161 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 109.02500153 0.75 l 109.02500153 125.55000305 l 0.375 125.55000305 l h f* Q q -0.625 -0.25 m 110.02500153 -0.25 l 110.02500153 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 173 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 66.3219986 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 174 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 66.3219986 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 109.77500153 0.75 m 422.42498779 0.75 l 422.42498779 125.55000305 l 109.77500153 125.55000305 l h f* Q q 1 0 0 1 109.40000153 0 cm -0.625 -0.25 m 314.0249939 -0.25 l 314.0249939 126.55000305 l -0.625 126.55000305 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 175 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(C12)-1(or)1(f10)-1(,)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 41.57699966 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 46.07699966 11.72200012 Tm [(also)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 63.33399963 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 67.83399963 11.72200012 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 96.65299988 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 101.15299988 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 110.29399872 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 114.79399872 11.72200012 Tm [(MYG)1(1)-1(,)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 143.15600586 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 147.65600586 11.72200012 Tm [(MYG)1(1)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 173.852005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 178.352005 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 184.91299438 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 189.41299438 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 194.38800049 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 198.88800049 11.72200012 Tm [(37)-1(6)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 214.72099304 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 219.22099304 11.72200012 Tm [(amino)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 246.29100037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 250.79100037 11.72200012 Tm [(acid)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 268.43099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 272.93099976 11.72200012 Tm [(nuc)-1(leo-)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(rial)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 60.18299866 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 64.68299866 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 95.98999786 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 100.48999786 27.3220005 Tm [(belonging)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 144.46200562 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 148.96200562 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 158.03700256 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 162.53700256 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 176.53799438 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 181.03799438 27.3220005 Tm [(UP)1(F)-1(01)-1(60)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 219.15600586 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 223.65600586 27.3220005 Tm [(\(MYG)1(1)-1(\))] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 255.86399841 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 260.36401367 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 288.61199951 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 293.11199951 27.3220005 Tm [(M)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(YG)1(1)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 17.40200043 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 21.90200043 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 28.46299934 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 32.96300125 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 70.47000122 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 74.97000122 42.92200089 Tm [(by)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 85.48200226 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 89.98200226 42.92200089 Tm [(a)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 94.95700073 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 99.45700073 42.92200089 Tm [(gene)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 120.97299957 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 125.47299957 42.92200089 Tm [(th)1(at)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 142.69500732 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 147.19500732 42.92200089 Tm [(map)1(s)] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 170.51699829 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 175.01699829 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 184.09199524 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 188.59199524 42.92200089 Tm [(human)] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 218.63299561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 223.13299561 42.92200089 Tm [(chromos)1(ome)] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 279.92800903 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 284.42800903 42.92200089 Tm [(12)-1(q)] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(13)-1(.13)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 23.27799988 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 27.77799988 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 44.05500031 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 48.55500031 58.52199936 Tm [(is)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 55.11600113 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 59.61600113 58.52199936 Tm [(ubiquito)1(usly)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 112.94799805 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 117.44799805 58.52199936 Tm [(expressed)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 160.602005 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 165.102005 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 173.04299927 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 177.54299927 58.52199936 Tm [(simple)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 205.78700256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 210.28700256 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 219.42799377 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 223.92799377 58.52199936 Tm [(well)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 240.92999268 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 245.42999268 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 254.57099915 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 259.0710144 58.52199936 Tm [(complex)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 295.54998779 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 300.04998779 58.52199936 Tm [(e)] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(uk)-1(a)1(ry)-1(o)1(tes,)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 44.13399887 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 48.63399887 74.12200165 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 67.02999878 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 71.52999878 74.12200165 Tm [(hig)1(he)-1(s)1(t)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 103.38999939 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 107.88999939 74.12200165 Tm [(leve)-1(ls)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 131.78300476 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 136.28300476 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 144.22399902 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 148.72399902 74.12200165 Tm [(test)1(i)-1(s)1(.)] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 173.42999268 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 177.92999268 74.12200165 Tm [(Considered)] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 226.94200134 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 231.44200134 74.12200165 Tm [(to)] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 240.51699829 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 245.01699829 74.12200165 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 265.36401367 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 269.86401367 74.12200165 Tm [(a)] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 274.83898926 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 279.33898926 74.12200165 Tm [(metal)] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(-d)1(e)-1(p)1(e)-1(ndent)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 50.91899872 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 55.41899872 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 86.72599792 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 91.22599792 89.72200012 Tm [(hydro)1(lase)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 133.08799744 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 137.58799744 89.72200012 Tm [(\(UP)1(F)-1(016)-1(0\))] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 181.71800232 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 186.21800232 89.72200012 Tm [(do)1(main,)] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 221.21200562 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 225.71200562 89.72200012 Tm [(MYG)1(1)] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 251.90800476 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 256.4079895 89.72200012 Tm [(exhibit)1(s)] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 289.67498779 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 294.17498779 89.72200012 Tm [(a)] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 299.1499939 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(mito)1(c)-1(ho)1(n)-1(d)1(rial)] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 60.18299866 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 64.68299866 105.3219986 Tm [(ta)1(rgeting)] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 104.36100006 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 108.86100006 105.3219986 Tm [(signal)] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 134.09399414 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 138.59399414 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 146.53500366 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 151.03500366 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 165.03599548 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 169.53599548 105.3219986 Tm [(N-t)1(e)-1(r)1(mi)-1(na)1(l)] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 216.38600159 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 310 >> BDC BT 1 0 0 -1 220.88600159 105.3219986 Tm [(region)] TJ ET EMC /P <</MCID 311 >> BDC BT 1 0 0 -1 248.8480072 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 312 >> BDC BT 1 0 0 -1 253.3480072 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 313 >> BDC BT 1 0 0 -1 269.625 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 314 >> BDC BT 1 0 0 -1 274.125 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 315 >> BDC BT 1 0 0 -1 279.1000061 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 316 >> BDC BT 1 0 0 -1 283.6000061 105.3219986 Tm [(Pat)1(7)] TJ ET EMC /P <</MCID 317 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(-t)1(ype)] TJ ET EMC /P <</MCID 318 >> BDC BT 1 0 0 -1 22.86499977 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 319 >> BDC BT 1 0 0 -1 27.36499977 120.92199707 Tm [(nuc)-1(lear)] TJ ET EMC /P <</MCID 320 >> BDC BT 1 0 0 -1 58.88299942 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 321 >> BDC BT 1 0 0 -1 63.38299942 120.92199707 Tm [(localizat)1(ion)] TJ ET EMC /P <</MCID 322 >> BDC BT 1 0 0 -1 112.19300079 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 323 >> BDC BT 1 0 0 -1 116.69300079 120.92199707 Tm [(signal)] TJ ET EMC /P <</MCID 324 >> BDC BT 1 0 0 -1 141.92599487 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 325 >> BDC BT 1 0 0 -1 146.42599487 120.92199707 Tm [(in)] TJ ET EMC /P <</MCID 326 >> BDC BT 1 0 0 -1 154.36700439 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 327 >> BDC BT 1 0 0 -1 158.86700439 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 328 >> BDC BT 1 0 0 -1 172.86799622 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 329 >> BDC BT 1 0 0 -1 177.36799622 120.92199707 Tm [(region)] TJ ET EMC /P <</MCID 330 >> BDC BT 1 0 0 -1 205.33000183 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 331 >> BDC BT 1 0 0 -1 209.83000183 120.92199707 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 332 >> BDC BT 1 0 0 -1 246.9019928 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 333 >> BDC BT 1 0 0 -1 251.4019928 120.92199707 Tm [(amino)] TJ ET EMC /P <</MCID 334 >> BDC BT 1 0 0 -1 278.47198486 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 335 >> BDC BT 1 0 0 -1 282.97198486 120.92199707 Tm [(acids)] TJ ET EMC /P <</MCID 336 >> BDC BT 1 0 0 -1 304.77801514 120.92199707 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 240 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 0.75 m 109.40000153 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 17.10000038 m 109.40000153 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 33.45000076 m 109.40000153 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 49.80000305 m 109.40000153 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 66.15000153 m 109.40000153 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 82.5 m 109.40000153 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 98.84999847 m 109.40000153 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 109.40000153 115.19999695 m 109.40000153 240 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 240 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 422.42498779 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 422.42498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 422.42498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 422.42498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 422.42498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 422.42498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 422.42498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 240.375 m 423.17498779 240.375 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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