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g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(TC)-1(F12)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 125.93299866 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 178.43299866 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 183.68299866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TCF)-1(1)1(2)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 109.91699982 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 112.29100037 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 141.06300354 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 143.43699646 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 193.75799561 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 196.13200378 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 233.92799377 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(transcripti)-1(on)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 117.83799744 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 120.21199799 12.82499981 Tm [(factor)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 145.60099792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 147.9750061 12.82499981 Tm [(12;)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 161.42799377 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 163.80200195 12.82499981 Tm [(HEB;)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 183.99200439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 186.36599731 12.82499981 Tm [(CRS)-1(3)1(;)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 210.62199402 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 212.9960022 12.82499981 Tm [(HTF)-1(4;)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 237.61099243 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 239.98500061 12.82499981 Tm [(TC)-1(F-12;)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 272.19299316 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 274.56698608 12.82499981 Tm [(bHL)-1(Hb20;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 316.55200195 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 318.92599487 12.82499981 Tm [(HsT17266)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 361.29998779 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 43 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 44 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 47 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 48 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 49 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 60 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 61 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 63 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 64 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 67 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TC)-1(F12)] TJ ET EMC /P <</MCID 68 >> BDC BT 1 0 0 -1 89.18299866 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 69 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 70 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 73 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <</MCID 74 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 88 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 89 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 90 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 91 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 116.92500305 0.75 l 116.92500305 141.1499939 l 0.375 141.1499939 l h f* Q q -0.625 -0.25 m 117.92500305 -0.25 l 117.92500305 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 92 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 74.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 93 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 74.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.67500305 0.75 m 422.42498779 0.75 l 422.42498779 141.1499939 l 117.67500305 141.1499939 l h f* Q q 1 0 0 1 117.30000305 0 cm -0.625 -0.25 m 306.125 -0.25 l 306.125 142.1499939 l -0.625 142.1499939 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 95 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 96 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(ba)1(sic)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 274.04501343 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 278.54501343 11.72200012 Tm [(heli)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(x-)1(l)-1(o)1(op-)1(hel)-1(ix)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 51.93500137 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 56.43500137 27.3220005 Tm [(\(bHLH)-1(\))] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 86.73500061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 91.23500061 27.3220005 Tm [(E-)1(prot)1(e)-1(in)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 131.38299561 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 135.88299561 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 161.96499634 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 166.46499634 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 183.68699646 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 188.18699646 27.3220005 Tm [(rec)-1(o)1(gnizes)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 234.36000061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 238.86000061 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 252.86099243 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 257.36099243 27.3220005 Tm [(conse)-1(nsu)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(s)] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 4.16599989 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 8.66600037 42.92200089 Tm [(binding)] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 41.81000137 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 46.31000137 42.92200089 Tm [(site)] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 61.33100128 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 65.83100128 42.92200089 Tm [(\(E-)1(box\))] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 96.71600342 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 101.21600342 42.92200089 Tm [(CANNTG)1(.)] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 142.22099304 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 146.72099304 42.92200089 Tm [(This)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 163.98300171 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 168.48300171 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 205.99000549 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 210.49000549 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 241.79699707 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 246.29699707 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 252.85800171 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 257.35800171 42.92200089 Tm [(expresse)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(d)] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 5.75699997 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 10.25699997 58.52199936 Tm [(in)] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 18.19799995 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 22.69799995 58.52199936 Tm [(many)] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 46.41500092 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 50.91500092 58.52199936 Tm [(tiss)1(u)-1(es,)] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 81.98000336 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 86.48000336 58.52199936 Tm [(amo)1(n)-1(g)] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 116.91200256 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 121.41200256 58.52199936 Tm [(th)1(e)-1(m)] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 143.84599304 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 148.34599304 58.52199936 Tm [(ske)-1(leta)1(l)] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 180.74200439 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 185.24200439 58.52199936 Tm [(musc)-1(le,)] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 217.56799316 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 222.06799316 58.52199936 Tm [(th)1(y)-1(mus,)] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 256.03799438 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 260.53799438 58.52199936 Tm [(B-)] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 270.07901001 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 274.57901001 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 290.85598755 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(T-ce)-1(lls,)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 29.79500008 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 34.29499817 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 50.5719986 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 55.0719986 74.12200165 Tm [(may)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 73.24299622 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 77.74299622 74.12200165 Tm [(pa)1(rticipat)1(e)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 123.74099731 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 128.24099731 74.12200165 Tm [(in)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 136.18200684 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 140.68200684 74.12200165 Tm [(regulat)1(i)-1(ng)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 184.94799805 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 189.44799805 74.12200165 Tm [(line)-1(ag)1(e)-1(-)1(spec)-1(if)1(i)-1(c)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 256.57901001 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 261.07901001 74.12200165 Tm [(gene)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 282.59500122 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 287.09500122 74.12200165 Tm [(ex)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(pression)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 36.2859993 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 40.7859993 89.72200012 Tm [(th)1(rough)] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 75.68299866 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 80.18299866 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 94.18399811 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 98.68399811 89.72200012 Tm [(fo)1(rmatio)1(n)] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 141.38600159 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 145.88600159 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 154.72799683 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 159.22799683 89.72200012 Tm [(heterod)1(ime)-1(rs)] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 216.78799438 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 221.28799438 89.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 239.68400574 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 244.18400574 89.72200012 Tm [(ot)1(her)] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 267.34298706 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 271.84298706 89.72200012 Tm [(bHLH)] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 296.13198853 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(E-)1(prot)1(e)-1(ins.)] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 46.48099899 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 50.98099899 105.3219986 Tm [(Se)-1(v)1(e)-1(ra)1(l)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 81.91899872 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 86.41899872 105.3219986 Tm [(alt)1(e)-1(rnat)1(ive)-1(ly)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 138.94200134 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 143.44200134 105.3219986 Tm [(splice)-1(d)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 173.522995 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 178.022995 105.3219986 Tm [(tr)1(ansc)-1(rip)1(t)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 218.94500732 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 223.44500732 105.3219986 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 257.01501465 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 261.51501465 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 270.35699463 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 274.85699463 105.3219986 Tm [(th)1(is)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 290.31298828 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(gene)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 21.51600075 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 26.01600075 120.92199707 Tm [(ha)1(ve)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 46.36299896 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 50.86299896 120.92199707 Tm [(been)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 72.37000275 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 76.87000275 120.92199707 Tm [(described,)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 121.02200317 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 125.52200317 120.92199707 Tm [(but)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 140.16900635 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 144.66900635 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 158.66999817 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 163.16999817 120.92199707 Tm [(full-length)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 208.21800232 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 212.71800232 120.92199707 Tm [(nature)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 240.67999268 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 245.17999268 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 254.02200317 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 258.52200317 120.92199707 Tm [(some)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 281.94900513 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 286.44900513 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 295.29098511 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(th)1(e)-1(se)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 23.27300072 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 27.77300072 136.52200317 Tm [(var)1(i)-1(a)1(n)-1(t)1(s)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 61.3429985 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 65.84300232 136.52200317 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 80.52500153 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 85.02500153 136.52200317 Tm [(not)] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 99.64600372 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 104.14600372 136.52200317 Tm [(been)] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 125.65299988 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 130.15299988 136.52200317 Tm [(determine)-1(d)1(.)] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 182.31599426 136.52200317 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 141.1499939 cm q /GS2 gs 1 g 0.375 0.75 m 116.92500305 0.75 l 116.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 117.92500305 -0.25 l 117.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 260 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 261 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 117.67500305 16.35000038 l h f* Q q 1 0 0 1 117.30000305 0 cm -0.625 -0.25 m 306.125 -0.25 l 306.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 262 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(WB)] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 14.80500031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 157.5 cm q /GS2 gs 1 g 0.375 0.75 m 116.92500305 0.75 l 116.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 117.92500305 -0.25 l 117.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 264 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 269 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 117.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 117.67500305 16.35000038 l h f* Q q 1 0 0 1 117.30000305 0 cm -0.625 -0.25 m 306.125 -0.25 l 306.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 270 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TCF1)-1(2)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 26.5170002 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.30000305 0.75 m 117.30000305 141.1499939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.30000305 141.8999939 m 117.30000305 157.5 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 117.30000305 158.25 m 117.30000305 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 173.8500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 141.5249939 m 422.42498779 141.5249939 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 157.875 m 422.42498779 157.875 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 174.2250061 m 423.17498779 174.2250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
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