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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1499939 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 74.13200378 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 145.89599609 23.67700005 Tm 0 Tr [(TBL1)1(XR1)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 230.727005 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 341.16699219 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(TBL)-1(1)1(X)-1(R1)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 136.78700256 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 189.28700256 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.28700256 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TBL1XR1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.77100372 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.14499664 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.91700745 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.29100037 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.98599243 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.78199768 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(transdu)-1(cin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.23000336 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.60399628 12.82499981 Tm [(beta)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.89199829 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.26600647 12.82499981 Tm [(li)-1(ke)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.08299255 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.45700073 12.82499981 Tm [(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.77900696 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.15299988 12.82499981 Tm [(X-l)-1(in)-1(k)1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.66799927 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.04200745 12.82499981 Tm [(re)1(ceptor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 230.82299805 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.19700623 12.82499981 Tm [(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.32800293 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.70199585 12.82499981 Tm [(C21;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.7539978 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.12799072 12.82499981 Tm [(DC42;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.64001465 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.01400757 12.82499981 Tm [(IRA1)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 315.56698608 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 317.94100952 12.82499981 Tm [(MRD41;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 352.5329895 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 354.90701294 12.82499981 Tm [(TBL)-1(R1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 381.17199707 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TBL)-1(1)1(X)-1(R1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.03700256 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.3480072 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 136.42500305 0.75 l 136.42500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 137.42500305 -0.25 l 137.42500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 137.17500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 137.17500305 172.3500061 l h f* Q q 1 0 0 1 136.80000305 0 cm -0.625 -0.25 m 286.625 -0.25 l 286.625 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.3390007 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.8390007 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.81399918 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.31400299 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.57800293 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.07800293 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.91999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.41999817 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.42100525 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.92100525 11.72200012 Tm [(WD)1(4)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.49000549 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.99000549 11.72200012 Tm [(repeat-)1(c)-1(o)1(n)-1(t)1(ainin)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.35600281 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.85600281 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.37200928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.08200073 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.58200073 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 46.85900116 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.35900116 27.3220005 Tm [(sha)1(re)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.75 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.25 27.3220005 Tm [(seque)-1(nce)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.09700012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.59700012 27.3220005 Tm [(similarit)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.30400085 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.80400085 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.19999695 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.69999695 27.3220005 Tm [(tr)1(ansduc)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.93299866 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.43299866 27.3220005 Tm [(\(beta)1(\)-li)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ke)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.00599957 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.50599957 42.92200089 Tm [(1X-lin)-1(ked)] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.58200073 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.08200073 42.92200089 Tm [(\(TB)-1(L1X\).)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.76799774 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.26799774 42.92200089 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.07499695 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.57499695 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.88200378 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.38200378 42.92200089 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.88900757 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.38900757 42.92200089 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.90100098 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.40100098 42.92200089 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.85699463 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.35699463 42.92200089 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.8730011 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.37298584 42.92200089 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.93399048 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.43399048 42.92200089 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ough)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.91900063 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.41900063 58.52199936 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.49399948 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.99399948 58.52199936 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.84799957 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.34799957 58.52199936 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.32299805 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.82299805 58.52199936 Tm [(component)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.51200104 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.01200104 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.85400391 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.35400391 58.52199936 Tm [(bo)1(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.71800232 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.21800232 58.52199936 Tm [(nuc)-1(lear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.73599243 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.23599243 58.52199936 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.65800476 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.15800476 58.52199936 Tm [(corepres)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(sor)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.32400036 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.8239994 74.12200165 Tm [(\(N-Co)1(R\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.66400146 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.16400146 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.44100189 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.94100189 74.12200165 Tm [(hist)1(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.77100372 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.27100372 74.12200165 Tm [(deace)-1(t)1(yl)-1(a)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.48699951 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.98699951 74.12200165 Tm [(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.26499939 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.76499939 74.12200165 Tm [(\(HDAC)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.94000244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.44000244 74.12200165 Tm [(3\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.72399902 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.22399902 74.12200165 Tm [(complexe)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.14199829 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.27700043 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.77700043 89.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.33799934 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.83799934 89.72200012 Tm [(required)] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.3789978 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.8789978 89.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.15699768 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.65699768 89.72200012 Tm [(tr)1(ansc)-1(rip)1(tional)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.61099243 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.11099243 89.72200012 Tm [(activat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.06100464 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.56100464 89.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.07299805 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.57299805 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.54800415 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.04800415 89.72200012 Tm [(var)1(i)-1(ety)] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.80099487 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.30099487 89.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.14300537 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.64300537 89.72200012 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ranscript)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.23099899 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.73099899 105.3219986 Tm [(fa)1(c)-1(t)1(ors.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.18299866 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.68299866 105.3219986 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.53199768 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 140.03199768 105.3219986 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.9730072 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.4730072 105.3219986 Tm [(th)1(e)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.7460022 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.2460022 105.3219986 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.76199341 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.26199341 105.3219986 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.60899353 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.10899353 105.3219986 Tm [(been)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.61599731 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.11599731 105.3219986 Tm [(asso)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ci)-1(a)1(ted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.09900093 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.59900093 120.92199707 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.99499893 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.49499893 120.92199707 Tm [(some)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.92199707 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.42199707 120.92199707 Tm [(autism)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.29000092 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.79000092 120.92199707 Tm [(spectrum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.09199524 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.59199524 120.92199707 Tm [(diso)1(rders,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.69999695 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.19999695 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.477005 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.977005 120.92199707 Tm [(one)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.35099792 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.85099792 120.92199707 Tm [(finding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.36700439 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(sugg)1(e)-1(st)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.01699829 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.51699829 136.52200317 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.73899841 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.23899841 136.52200317 Tm [(ha)1(ploinsufficie)-1(nc)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.74499512 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.24499512 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.08700562 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.58700562 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.04299927 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.54299927 136.52200317 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.05900574 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.55900574 136.52200317 Tm [(may)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.72999573 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.22999573 136.52200317 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.08399963 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.58399963 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.55900574 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.05900574 136.52200317 Tm [(cause)] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.36499023 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 152.12199402 Tm [(intelle)-1(ctual)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.42100143 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.92099762 152.12199402 Tm [(disa)1(bility)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.26300049 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.76300049 152.12199402 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.15899658 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 130.65899658 152.12199402 Tm [(dysmor)1(phism.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.38699341 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.88699341 152.12199402 Tm [(Mutat)1(ions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.73599243 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.23599243 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.17700195 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 256.67700195 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.13299561 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 167.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.51600075 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.01600075 167.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.1570015 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.6570015 167.72200012 Tm [(well)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.6590004 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.1590004 167.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.30000305 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.80000305 167.72200012 Tm [(rec)-1(urrent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.27999878 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.77999878 167.72200012 Tm [(tr)1(ansloc)-1(a)1(tions)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.04200745 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.54200745 167.72200012 Tm [(involving)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.7460022 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.2460022 167.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.70199585 167.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.20199585 167.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.71798706 167.72200012 Tm [( )] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 136.80000305 0.75 m 136.80000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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