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TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 117.31500244 12.82499981 Tm [(72-4)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 136.49499512 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 138.8690033 12.82499981 Tm [(/)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 142.92399597 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 21 >> BDC BT 1 0 0 -1 145.29800415 12.82499981 Tm [(CA)] TJ ET EMC /P <</MCID 22 >> BDC BT 1 0 0 -1 156.97200012 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 23 >> BDC BT 1 0 0 -1 159.34599304 12.82499981 Tm [(72-4)] TJ ET EMC /P <</Lang (zh-CN) /MCID 24 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 181.15100098 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 25 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 233.65100098 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 238.90100098 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 27 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 28 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TAG)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 101.55000305 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 103.9240036 12.82499981 Tm [(72-4)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 123.10399628 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 125.47799683 12.82499981 Tm [(/)] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 129.53300476 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 131.90699768 12.82499981 Tm [(CA)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 143.58099365 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 145.95500183 12.82499981 Tm [(72-4)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 165.13499451 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 167.50900269 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 196.28100586 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 198.65499878 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 248.97599792 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 251.3500061 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 289.14599609 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010001100120013000E>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 134.60800171 12.82499981 Tm [<001C001D>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 155.60800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001E>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 62 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001F000E>] TJ ET EMC /P <</MCID 63 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 65 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 66 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 67 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 68 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0020000E>] TJ ET EMC /P <</MCID 69 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TAG)] TJ ET EMC /P <</MCID 71 >> BDC BT 1 0 0 -1 80.81600189 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 72 >> BDC BT 1 0 0 -1 83.19000244 12.82499981 Tm [(72-4)] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 102.37000275 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 104.7440033 12.82499981 Tm [(/)] TJ ET EMC /P <</MCID 75 >> BDC BT 1 0 0 -1 108.7990036 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 76 >> BDC BT 1 0 0 -1 111.17299652 12.82499981 Tm [(CA)] TJ ET EMC /P <</MCID 77 >> BDC BT 1 0 0 -1 122.84700012 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 78 >> BDC BT 1 0 0 -1 125.22100067 12.82499981 Tm [(72-4)] TJ ET EMC /P <</MCID 79 >> BDC BT 1 0 0 -1 144.40100098 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 80 >> BDC BT 1 0 0 -1 147 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 168 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 82 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0021002200230024000E>] TJ ET EMC /P <</MCID 83 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 84 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 85 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 86 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0025>] TJ ET EMC /P <</MCID 87 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 88 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0026>] TJ ET EMC /P <</MCID 89 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 90 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0027000E>] TJ ET EMC /P <</MCID 91 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 92 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 93 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 94 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 95 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800120028000E>] TJ ET EMC /P <</MCID 96 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 146.84100342 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 147 12.82499981 Tm /GS2 gs 0 g [( )] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 149.37399292 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 348.65100098 m 416.75 348.65100098 l 416.75 379.85101318 l -1.45000005 379.85101318 l h f* Q q 1 0 0 1 0 348.65100098 cm /P <</MCID 104 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 105 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 106 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 379.85101318 cm /P <</MCID 107 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 407.79000854 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 47.54999924 l 0.375 47.54999924 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 48.54999924 l -0.625 48.54999924 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 108 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 27.3220005 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 109 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 47.54999924 l 141.67500305 47.54999924 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 48.54999924 l -0.625 48.54999924 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 110 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(mRNA)1(-c)-1(a)1(pping)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 66.53299713 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 71.03299713 11.72200012 Tm [(methyltr)1(ansferase)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 148.01199341 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 152.51199341 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 169.73399353 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 174.23399353 11.72200012 Tm [(methylat)1(e)-1(s)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 221.42700195 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 225.92700195 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 239.92799377 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 244.42799377 11.72200012 Tm [(N7)] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 257.02301025 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 261.52301025 11.72200012 Tm [(po)] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(sitio)1(n)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 23.57699966 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 28.07699966 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 36.91899872 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 41.41899872 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 55.41999817 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 59.91999817 27.3220005 Tm [(ad)1(ded)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 87.27200317 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 91.77200317 27.3220005 Tm [(guanos)1(i)-1(ne)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 136.52999878 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 141.02999878 27.3220005 Tm [(to)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 150.10499573 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 154.60499573 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 168.60600281 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 173.10600281 27.3220005 Tm [(5')-1(-)1(c)-1(ap)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 199.82000732 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 204.32000732 27.3220005 Tm [(st)1(ruc)-1(ture)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 242.7769928 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 247.2769928 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 256.11898804 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 260.61898804 27.3220005 Tm [(m)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(RNA)1(s.)] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 25.85700035 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 30.35700035 42.92200089 Tm [(Bi)-1(nd)1(s)] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 53.86800003 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 58.36800003 42.92200089 Tm [(RNA)] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 77.89299774 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 82.39299774 42.92200089 Tm [(containing)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 128.13999939 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 132.63999939 42.92200089 Tm [(5')-1(-)1(termin)-1(a)1(l)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 179.75799561 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 184.25799561 42.92200089 Tm [(Gp)1(ppC.)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 216.38200378 42.92200089 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 47.54999924 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 156 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Applic)1(ations:)] TJ ET EMC /P <</MCID 157 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 59.08000183 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 158 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(IHC)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 15.62699986 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 63.90000153 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 160 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Name)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 26.90800095 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 31.40800095 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 40.97000122 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 45.47000122 11.72200012 Tm [(antibod)1(y)-1(:)] TJ ET EMC /P <</MCID 165 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 88.51899719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 166 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TAG)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 18.18499947 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 22.68499947 11.72200012 Tm [(72)-1(-)1(4)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 42.41199875 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 46.91199875 11.72200012 Tm [(/)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 50.75699997 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 55.25699997 11.72200012 Tm [(CA)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 67.61000061 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 72.11000061 11.72200012 Tm [(72)-1(-)1(4)] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 91.83699799 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 80.25 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 31.95000076 l 0.375 31.95000076 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 176 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 19.52199936 Tm /GS2 gs 0.13333334 g [(Immunogen:)] TJ ET EMC /P <</MCID 177 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.89400101 19.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 31.95000076 l 141.67500305 31.95000076 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 32.95000076 l -0.625 32.95000076 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 178 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Membrane-enric)-1(hed)] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 88.44000244 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 92.94000244 11.72200012 Tm [(fra)1(c)-1(t)1(ion)] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 126 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 130.5 11.72200012 Tm [(of)] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 139.34199524 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 143.84199524 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 148.81700134 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 153.31700134 11.72200012 Tm [(human)] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 183.35800171 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 187.85800171 11.72200012 Tm [(breast)] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 214.64300537 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 219.14300537 11.72200012 Tm [(carci)-1(noma)] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 263.65100098 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 268.15100098 11.72200012 Tm [(li)] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ver)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 13.2670002 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 17.7670002 27.3220005 Tm [(metast)1(asis)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 62.85499954 27.3220005 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 112.19999695 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 197 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <</MCID 200 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 201 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(mRNA)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 27.95800018 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 32.45800018 11.72200012 Tm [(cap)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 47.69400024 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 52.19400024 11.72200012 Tm [(guanine)-1(-)1(N7)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 103.5530014 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 108.0530014 11.72200012 Tm [(methyltr)1(ansferase)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 185.03199768 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 128.55000305 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 209 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(P)-1(r)1(o)-1(t:)] TJ ET EMC /P <</MCID 210 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 46.56900024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 211 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q9XV)-1(S1)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 34.97600174 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 144.8999939 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 213 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(IH)-1(C)] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 16.47100067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 20.97100067 11.72200012 Tm [(positive)] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 56.80799866 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 61.30799866 11.72200012 Tm [(control:)] TJ ET EMC /P <</MCID 218 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 96.39399719 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 219 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(human)] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 30.04100037 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 34.54100037 11.72200012 Tm [(colon)] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 58.43799973 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 62.93799973 11.72200012 Tm [(tiss)1(u)-1(e)] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 87.66999817 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 161.25 cm q /GS2 gs 1 g 0.375 0.75 m 140.92500305 0.75 l 140.92500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 141.92500305 -0.25 l 141.92500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 225 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(IH)-1(C)] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 16.47100067 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 20.97100067 11.72200012 Tm [(Recommend)] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 77.78299713 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 82.28299713 11.72200012 Tm [(di)1(lution:)] TJ ET EMC /P <</MCID 230 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 120.1289978 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 141.67500305 0.75 m 422.42498779 0.75 l 422.42498779 16.35000038 l 141.67500305 16.35000038 l h f* Q q 1 0 0 1 141.30000305 0 cm -0.625 -0.25 m 282.125 -0.25 l 282.125 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 231 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(30)-1(-)1(1)-1(50)] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 30.28300095 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 177.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 0.75 m 141.30000305 47.54999924 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 48.29999924 m 141.30000305 63.90000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 64.65000153 m 141.30000305 80.25 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 81 m 141.30000305 112.19999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 112.94999695 m 141.30000305 128.55000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 129.30000305 m 141.30000305 144.90000916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 145.65000916 m 141.30000305 161.25001526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 141.30000305 162.00001526 m 141.30000305 177.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 177.60002136 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 47.92499924 m 422.42498779 47.92499924 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 64.27500153 m 422.42498779 64.27500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 80.625 m 422.42498779 80.625 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 112.57499695 m 422.42498779 112.57499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 128.92500305 m 422.42498779 128.92500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 145.27500916 m 422.42498779 145.27500916 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 161.62501526 m 422.42498779 161.62501526 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 177.97502136 m 423.17498779 177.97502136 l S Q Q q 1 0 0 1 0 586.14001465 cm Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
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