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g [<000A000B000C000D000E>] TJ ET EMC /P <</MCID 5 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [(  )] TJ ET EMC /P <</Lang (zh-CN) /MCID 6 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <</MCID 7 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(TAB1)] TJ ET EMC /P <</Lang (zh-CN) /MCID 8 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 121.97499847 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <</MCID 9 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 174.4750061 12.82499981 Tm [(  )] TJ ET EMC /P <</MCID 10 >> BDC BT 1 0 0 -1 184.9750061 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <</Lang (zh-CN) /MCID 11 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <</MCID 12 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 13 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(TAB)1(1)] TJ ET EMC /P <</MCID 14 >> BDC BT 1 0 0 -1 105.95899963 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 15 >> BDC BT 1 0 0 -1 108.33300018 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <</MCID 16 >> BDC BT 1 0 0 -1 137.10499573 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 17 >> BDC BT 1 0 0 -1 139.47900391 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 18 >> BDC BT 1 0 0 -1 189.80000305 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 19 >> BDC BT 1 0 0 -1 192.17399597 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <</MCID 20 >> BDC BT 1 0 0 -1 229.97000122 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <</Lang (zh-CN) /MCID 21 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <</MCID 22 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 23 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <</MCID 24 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 25 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TGF)-1(-beta)] TJ ET EMC /P <</MCID 26 >> BDC BT 1 0 0 -1 102.06700134 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 27 >> BDC BT 1 0 0 -1 104.44100189 12.82499981 Tm [(activate)1(d)] TJ ET EMC /P <</MCID 28 >> BDC BT 1 0 0 -1 143.86700439 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 29 >> BDC BT 1 0 0 -1 146.24099731 12.82499981 Tm [(kinas)-1(e)] TJ ET EMC /P <</MCID 30 >> BDC BT 1 0 0 -1 173.30099487 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 31 >> BDC BT 1 0 0 -1 175.67500305 12.82499981 Tm [(1)] TJ ET EMC /P <</MCID 32 >> BDC BT 1 0 0 -1 180.99699402 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 33 >> BDC BT 1 0 0 -1 183.3710022 12.82499981 Tm [(\(MAP)1(3K7\))] TJ ET EMC /P <</MCID 34 >> BDC BT 1 0 0 -1 226.31399536 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 35 >> BDC BT 1 0 0 -1 228.68800354 12.82499981 Tm [(bi)-1(nd)-1(in)-1(g)] TJ ET EMC /P <</MCID 36 >> BDC BT 1 0 0 -1 260.51599121 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 37 >> BDC BT 1 0 0 -1 262.89001465 12.82499981 Tm [(protein)] TJ ET EMC /P <</MCID 38 >> BDC BT 1 0 0 -1 294.27200317 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 39 >> BDC BT 1 0 0 -1 296.64599609 12.82499981 Tm [(1;)] TJ ET EMC /P <</MCID 40 >> BDC BT 1 0 0 -1 304.77700806 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 41 >> BDC BT 1 0 0 -1 307.15100098 12.82499981 Tm [(3'-Tab1;)] TJ ET EMC /P <</MCID 42 >> BDC BT 1 0 0 -1 341.79901123 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 43 >> BDC BT 1 0 0 -1 344.17300415 12.82499981 Tm [(MAP)1(3K7)1(IP1)] TJ ET EMC /P <</MCID 44 >> BDC BT 1 0 0 -1 394.14001465 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 147.41700745 cm /P <</Lang (zh-CN) /MCID 45 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <</MCID 46 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 47 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <</MCID 48 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 49 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 180.95599365 cm /P <</Lang (zh-CN) /MCID 50 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <</MCID 51 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 52 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <</MCID 53 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 54 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <</MCID 55 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <</Lang (zh-CN) /MCID 56 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <</MCID 57 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 214.49499512 cm /P <</Lang (zh-CN) /MCID 58 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <</MCID 59 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 60 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <</MCID 61 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 62 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 63 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 64 >> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 248.03399658 cm /P <</Lang (zh-CN) /MCID 65 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <</MCID 66 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [(    )] TJ ET EMC /P <</Lang (zh-CN) /MCID 67 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <</MCID 68 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 69 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(TAB1)] TJ ET EMC /P <</MCID 70 >> BDC BT 1 0 0 -1 85.22499847 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 281.57299805 cm /P <</Lang (zh-CN) /MCID 71 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <</MCID 72 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 73 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <</MCID 74 >> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 315.11199951 cm /P <</Lang (zh-CN) /MCID 75 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <</MCID 76 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 77 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <</MCID 78 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <</Lang (zh-CN) /MCID 79 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <</MCID 80 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 81 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <</MCID 82 >> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 83 >> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 348.65100098 cm /P <</Lang (zh-CN) /MCID 84 >> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <</MCID 85 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <</MCID 86 >> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <</MCID 87 >> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <</MCID 88 >> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <</MCID 89 >> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 382.19000244 m 416.75 382.19000244 l 416.75 413.39001465 l -1.45000005 413.39001465 l h f* Q q 1 0 0 1 0 382.19000244 cm /P <</MCID 90 >> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <</Lang (zh-CN) /MCID 91 >> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <</MCID 92 >> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 413.39001465 cm /P <</MCID 93 >> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 441.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 143.17500305 0.75 l 143.17500305 172.3500061 l 0.375 172.3500061 l h f* Q q -0.625 -0.25 m 144.17500305 -0.25 l 144.17500305 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 94 >> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 89.72200012 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <</MCID 95 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 89.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 143.92500305 0.75 m 422.42498779 0.75 l 422.42498779 172.3500061 l 143.92500305 172.3500061 l h f* Q q 1 0 0 1 143.55000305 0 cm -0.625 -0.25 m 279.875 -0.25 l 279.875 173.3500061 l -0.625 173.3500061 l h W n q 1 0 0 1 3.75 0.75 cm /P <</MCID 96 >> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <</MCID 97 >> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 98 >> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 99 >> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 100 >> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <</MCID 101 >> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 102 >> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <</MCID 103 >> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 104 >> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 105 >> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 106 >> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <</MCID 107 >> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 108 >> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(wa)1(s)] TJ ET EMC /P <</MCID 109 >> BDC BT 1 0 0 -1 175.352005 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 110 >> BDC BT 1 0 0 -1 179.852005 11.72200012 Tm [(identified)] TJ ET EMC /P <</MCID 111 >> BDC BT 1 0 0 -1 220.78300476 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 112 >> BDC BT 1 0 0 -1 225.28300476 11.72200012 Tm [(as)] TJ ET EMC /P <</MCID 113 >> BDC BT 1 0 0 -1 234.42399597 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 114 >> BDC BT 1 0 0 -1 238.92399597 11.72200012 Tm [(a)] TJ ET EMC /P <</MCID 115 >> BDC BT 1 0 0 -1 243.89900208 11.72200012 Tm [( )] TJ ET EMC /P <</MCID 116 >> BDC BT 1 0 0 -1 248.39900208 11.72200012 Tm [(regul)] TJ ET EMC /P <</MCID 117 >> BDC BT 1 0 0 -1 0 27.3220005 Tm [(at)1(or)] TJ ET EMC /P <</MCID 118 >> BDC BT 1 0 0 -1 17.48600006 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 119 >> BDC BT 1 0 0 -1 21.98600006 27.3220005 Tm [(of)] TJ ET EMC /P <</MCID 120 >> BDC BT 1 0 0 -1 30.82799911 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 121 >> BDC BT 1 0 0 -1 35.32799911 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <</MCID 122 >> BDC BT 1 0 0 -1 49.32899857 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 123 >> BDC BT 1 0 0 -1 53.82899857 27.3220005 Tm [(MAP)] TJ ET EMC /P <</MCID 124 >> BDC BT 1 0 0 -1 74.46099854 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 125 >> BDC BT 1 0 0 -1 78.96099854 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 126 >> BDC BT 1 0 0 -1 106.0490036 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 127 >> BDC BT 1 0 0 -1 110.5490036 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 128 >> BDC BT 1 0 0 -1 137.63699341 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 129 >> BDC BT 1 0 0 -1 142.13699341 27.3220005 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <</MCID 130 >> BDC BT 1 0 0 -1 169.2250061 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 131 >> BDC BT 1 0 0 -1 173.7250061 27.3220005 Tm [(MAP)1(3)-1(K7/T)-1(A)1(K1,)] TJ ET EMC /P <</MCID 132 >> BDC BT 1 0 0 -1 239.11999512 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 133 >> BDC BT 1 0 0 -1 243.61999512 27.3220005 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <</MCID 134 >> BDC BT 1 0 0 -1 268.7170105 27.3220005 Tm [( )] TJ ET EMC /P <</MCID 135 >> BDC BT 1 0 0 -1 0 42.92200089 Tm [(is)] TJ ET EMC /P <</MCID 136 >> BDC BT 1 0 0 -1 6.56099987 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 137 >> BDC BT 1 0 0 -1 11.06099987 42.92200089 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <</MCID 138 >> BDC BT 1 0 0 -1 39.88000107 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 139 >> BDC BT 1 0 0 -1 44.38000107 42.92200089 Tm [(to)] TJ ET EMC /P <</MCID 140 >> BDC BT 1 0 0 -1 53.45500183 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 141 >> BDC BT 1 0 0 -1 57.95500183 42.92200089 Tm [(mediat)1(e)] TJ ET EMC /P <</MCID 142 >> BDC BT 1 0 0 -1 93.08000183 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 143 >> BDC BT 1 0 0 -1 97.58000183 42.92200089 Tm [(var)1(i)-1(o)1(u)-1(s)] TJ ET EMC /P <</MCID 144 >> BDC BT 1 0 0 -1 128.54400635 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 145 >> BDC BT 1 0 0 -1 133.04400635 42.92200089 Tm [(intra)1(c)-1(ell)-1(ular)] TJ ET EMC /P <</MCID 146 >> BDC BT 1 0 0 -1 183.51100159 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 147 >> BDC BT 1 0 0 -1 188.01100159 42.92200089 Tm [(signaling)] TJ ET EMC /P <</MCID 148 >> BDC BT 1 0 0 -1 226.94200134 42.92200089 Tm [( )] TJ ET EMC /P <</MCID 149 >> BDC BT 1 0 0 -1 231.44200134 42.92200089 Tm [(pa)1(thw)1(ay)] TJ ET EMC /P <</MCID 150 >> BDC BT 1 0 0 -1 0 58.52199936 Tm [(s,)] TJ ET EMC /P <</MCID 151 >> BDC BT 1 0 0 -1 6.33300018 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 152 >> BDC BT 1 0 0 -1 10.83300018 58.52199936 Tm [(suc)-1(h)] TJ ET EMC /P <</MCID 153 >> BDC BT 1 0 0 -1 30.60000038 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 154 >> BDC BT 1 0 0 -1 35.09999847 58.52199936 Tm [(as)] TJ ET EMC /P <</MCID 155 >> BDC BT 1 0 0 -1 44.24100113 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 156 >> BDC BT 1 0 0 -1 48.74100113 58.52199936 Tm [(th)1(ose)] TJ ET EMC /P <</MCID 157 >> BDC BT 1 0 0 -1 72.62999725 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 158 >> BDC BT 1 0 0 -1 77.12999725 58.52199936 Tm [(induc)-1(ed)] TJ ET EMC /P <</MCID 159 >> BDC BT 1 0 0 -1 111.75 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 160 >> BDC BT 1 0 0 -1 116.25 58.52199936 Tm [(by)] TJ ET EMC /P <</MCID 161 >> BDC BT 1 0 0 -1 126.76200104 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 162 >> BDC BT 1 0 0 -1 131.26199341 58.52199936 Tm [(TGF)] TJ ET EMC /P <</MCID 163 >> BDC BT 1 0 0 -1 147.89500427 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 164 >> BDC BT 1 0 0 -1 152.39500427 58.52199936 Tm [(beta)1(,)] TJ ET EMC /P <</MCID 165 >> BDC BT 1 0 0 -1 173.7440033 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 166 >> BDC BT 1 0 0 -1 178.2440033 58.52199936 Tm [(interle)-1(ukin)] TJ ET EMC /P <</MCID 167 >> BDC BT 1 0 0 -1 223.96899414 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 168 >> BDC BT 1 0 0 -1 228.46899414 58.52199936 Tm [(1,)] TJ ET EMC /P <</MCID 169 >> BDC BT 1 0 0 -1 235.91299438 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 170 >> BDC BT 1 0 0 -1 240.41299438 58.52199936 Tm [(and)] TJ ET EMC /P <</MCID 171 >> BDC BT 1 0 0 -1 256.69000244 58.52199936 Tm [( )] TJ ET EMC /P <</MCID 172 >> BDC BT 1 0 0 -1 261.19000244 58.52199936 Tm [(W)] TJ ET EMC /P <</MCID 173 >> BDC BT 1 0 0 -1 0 74.12200165 Tm [(NT-1.)] TJ ET EMC /P <</MCID 174 >> BDC BT 1 0 0 -1 23.81399918 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 175 >> BDC BT 1 0 0 -1 28.31399918 74.12200165 Tm [(This)] TJ ET EMC /P <</MCID 176 >> BDC BT 1 0 0 -1 45.57600021 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 177 >> BDC BT 1 0 0 -1 50.07600021 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 178 >> BDC BT 1 0 0 -1 81.38300323 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 179 >> BDC BT 1 0 0 -1 85.88300323 74.12200165 Tm [(interacts)] TJ ET EMC /P <</MCID 180 >> BDC BT 1 0 0 -1 122.72699738 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 181 >> BDC BT 1 0 0 -1 127.22699738 74.12200165 Tm [(and)] TJ ET EMC /P <</MCID 182 >> BDC BT 1 0 0 -1 143.5039978 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 183 >> BDC BT 1 0 0 -1 148.0039978 74.12200165 Tm [(th)1(us)] TJ ET EMC /P <</MCID 184 >> BDC BT 1 0 0 -1 166.61000061 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 185 >> BDC BT 1 0 0 -1 171.11000061 74.12200165 Tm [(activat)1(es)] TJ ET EMC /P <</MCID 186 >> BDC BT 1 0 0 -1 208.66999817 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 187 >> BDC BT 1 0 0 -1 213.16999817 74.12200165 Tm [(TAK1)] TJ ET EMC /P <</MCID 188 >> BDC BT 1 0 0 -1 235.6519928 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 189 >> BDC BT 1 0 0 -1 240.1519928 74.12200165 Tm [(ki)-1(na)1(se)-1(.)] TJ ET EMC /P <</MCID 190 >> BDC BT 1 0 0 -1 269.40600586 74.12200165 Tm [( )] TJ ET EMC /P <</MCID 191 >> BDC BT 1 0 0 -1 0 89.72200012 Tm [(It)] TJ ET EMC /P <</MCID 192 >> BDC BT 1 0 0 -1 5.99900007 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 193 >> BDC BT 1 0 0 -1 10.4989996 89.72200012 Tm [(ha)1(s)] TJ ET EMC /P <</MCID 194 >> BDC BT 1 0 0 -1 25.18099976 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 195 >> BDC BT 1 0 0 -1 29.68099976 89.72200012 Tm [(been)] TJ ET EMC /P <</MCID 196 >> BDC BT 1 0 0 -1 51.18799973 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 197 >> BDC BT 1 0 0 -1 55.68799973 89.72200012 Tm [(sho)1(wn)] TJ ET EMC /P <</MCID 198 >> BDC BT 1 0 0 -1 83.76899719 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 199 >> BDC BT 1 0 0 -1 88.26899719 89.72200012 Tm [(th)1(at)] TJ ET EMC /P <</MCID 200 >> BDC BT 1 0 0 -1 105.49099731 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 201 >> BDC BT 1 0 0 -1 109.99099731 89.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 202 >> BDC BT 1 0 0 -1 123.99199677 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 203 >> BDC BT 1 0 0 -1 128.49200439 89.72200012 Tm [(C-t)1(e)-1(r)1(min)-1(a)1(l)] TJ ET EMC /P <</MCID 204 >> BDC BT 1 0 0 -1 174.04600525 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 205 >> BDC BT 1 0 0 -1 178.54600525 89.72200012 Tm [(po)1(rtion)] TJ ET EMC /P <</MCID 206 >> BDC BT 1 0 0 -1 210.46800232 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 207 >> BDC BT 1 0 0 -1 214.96800232 89.72200012 Tm [(of)] TJ ET EMC /P <</MCID 208 >> BDC BT 1 0 0 -1 223.80999756 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 209 >> BDC BT 1 0 0 -1 228.30999756 89.72200012 Tm [(th)1(is)] TJ ET EMC /P <</MCID 210 >> BDC BT 1 0 0 -1 243.76600647 89.72200012 Tm [( )] TJ ET EMC /P <</MCID 211 >> BDC BT 1 0 0 -1 248.26600647 89.72200012 Tm [(pro)1(te)] TJ ET EMC /P <</MCID 212 >> BDC BT 1 0 0 -1 0 105.3219986 Tm [(in)] TJ ET EMC /P <</MCID 213 >> BDC BT 1 0 0 -1 7.94099998 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 214 >> BDC BT 1 0 0 -1 12.44099998 105.3219986 Tm [(is)] TJ ET EMC /P <</MCID 215 >> BDC BT 1 0 0 -1 19.00200081 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 216 >> BDC BT 1 0 0 -1 23.50200081 105.3219986 Tm [(suff)1(i)-1(cie)-1(nt)] TJ ET EMC /P <</MCID 217 >> BDC BT 1 0 0 -1 62.76300049 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 218 >> BDC BT 1 0 0 -1 67.26300049 105.3219986 Tm [(fo)1(r)] TJ ET EMC /P <</MCID 219 >> BDC BT 1 0 0 -1 79.54100037 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 220 >> BDC BT 1 0 0 -1 84.04100037 105.3219986 Tm [(binding)] TJ ET EMC /P <</MCID 221 >> BDC BT 1 0 0 -1 117.18499756 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 222 >> BDC BT 1 0 0 -1 121.68499756 105.3219986 Tm [(and)] TJ ET EMC /P <</MCID 223 >> BDC BT 1 0 0 -1 137.96200562 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 224 >> BDC BT 1 0 0 -1 142.46200562 105.3219986 Tm [(activat)1(ion)] TJ ET EMC /P <</MCID 225 >> BDC BT 1 0 0 -1 184.41200256 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 226 >> BDC BT 1 0 0 -1 188.91200256 105.3219986 Tm [(of)] TJ ET EMC /P <</MCID 227 >> BDC BT 1 0 0 -1 197.7539978 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 228 >> BDC BT 1 0 0 -1 202.2539978 105.3219986 Tm [(TAK1,)] TJ ET EMC /P <</MCID 229 >> BDC BT 1 0 0 -1 226.90299988 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 230 >> BDC BT 1 0 0 -1 231.40299988 105.3219986 Tm [(wh)1(il)-1(e)] TJ ET EMC /P <</MCID 231 >> BDC BT 1 0 0 -1 253.94700623 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 232 >> BDC BT 1 0 0 -1 258.44699097 105.3219986 Tm [(a)] TJ ET EMC /P <</MCID 233 >> BDC BT 1 0 0 -1 263.42199707 105.3219986 Tm [( )] TJ ET EMC /P <</MCID 234 >> BDC BT 1 0 0 -1 0 120.92199707 Tm [(po)1(rtion)] TJ ET EMC /P <</MCID 235 >> BDC BT 1 0 0 -1 31.92200089 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 236 >> BDC BT 1 0 0 -1 36.42200089 120.92199707 Tm [(of)] TJ ET EMC /P <</MCID 237 >> BDC BT 1 0 0 -1 45.26399994 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 238 >> BDC BT 1 0 0 -1 49.76399994 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <</MCID 239 >> BDC BT 1 0 0 -1 63.76499939 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 240 >> BDC BT 1 0 0 -1 68.26499939 120.92199707 Tm [(N-t)1(e)-1(r)1(mi)-1(nus)] TJ ET EMC /P <</MCID 241 >> BDC BT 1 0 0 -1 117.45700073 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 242 >> BDC BT 1 0 0 -1 121.95700073 120.92199707 Tm [(acts)] TJ ET EMC /P <</MCID 243 >> BDC BT 1 0 0 -1 138.96400452 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 244 >> BDC BT 1 0 0 -1 143.46400452 120.92199707 Tm [(as)] TJ ET EMC /P <</MCID 245 >> BDC BT 1 0 0 -1 152.60499573 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 246 >> BDC BT 1 0 0 -1 157.10499573 120.92199707 Tm [(a)] TJ ET EMC /P <</MCID 247 >> BDC BT 1 0 0 -1 162.08000183 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 248 >> BDC BT 1 0 0 -1 166.58000183 120.92199707 Tm [(do)1(mi)-1(na)1(n)-1(t)1(-negat)1(ive)] TJ ET EMC /P <</MCID 249 >> BDC BT 1 0 0 -1 249.16200256 120.92199707 Tm [( )] TJ ET EMC /P <</MCID 250 >> BDC BT 1 0 0 -1 253.66200256 120.92199707 Tm [(inhi)] TJ ET EMC /P <</MCID 251 >> BDC BT 1 0 0 -1 0 136.52200317 Tm [(bit)1(or)] TJ ET EMC /P <</MCID 252 >> BDC BT 1 0 0 -1 20.65399933 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 253 >> BDC BT 1 0 0 -1 25.15399933 136.52200317 Tm [(of)] TJ ET EMC /P <</MCID 254 >> BDC BT 1 0 0 -1 33.99599838 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 255 >> BDC BT 1 0 0 -1 38.49599838 136.52200317 Tm [(TGF)] TJ ET EMC /P <</MCID 256 >> BDC BT 1 0 0 -1 55.12900162 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 257 >> BDC BT 1 0 0 -1 59.62900162 136.52200317 Tm [(beta)1(,)] TJ ET EMC /P <</MCID 258 >> BDC BT 1 0 0 -1 80.97799683 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 259 >> BDC BT 1 0 0 -1 85.47799683 136.52200317 Tm [(sugg)1(e)-1(st)1(in)-1(g)] TJ ET EMC /P <</MCID 260 >> BDC BT 1 0 0 -1 133.0269928 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 261 >> BDC BT 1 0 0 -1 137.5269928 136.52200317 Tm [(th)1(at)] TJ ET EMC /P <</MCID 262 >> BDC BT 1 0 0 -1 154.74899292 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 263 >> BDC BT 1 0 0 -1 159.24899292 136.52200317 Tm [(th)1(is)] TJ ET EMC /P <</MCID 264 >> BDC BT 1 0 0 -1 174.70500183 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 265 >> BDC BT 1 0 0 -1 179.20500183 136.52200317 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 266 >> BDC BT 1 0 0 -1 210.51199341 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 267 >> BDC BT 1 0 0 -1 215.01199341 136.52200317 Tm [(may)] TJ ET EMC /P <</MCID 268 >> BDC BT 1 0 0 -1 233.18299866 136.52200317 Tm [( )] TJ ET EMC /P <</MCID 269 >> BDC BT 1 0 0 -1 237.68299866 136.52200317 Tm [(func)-1(t)1(io)] TJ ET EMC /P <</MCID 270 >> BDC BT 1 0 0 -1 0 152.12199402 Tm [(n)] TJ ET EMC /P <</MCID 271 >> BDC BT 1 0 0 -1 5.546 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 272 >> BDC BT 1 0 0 -1 10.04599953 152.12199402 Tm [(as)] TJ ET EMC /P <</MCID 273 >> BDC BT 1 0 0 -1 19.18700027 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 274 >> BDC BT 1 0 0 -1 23.68700027 152.12199402 Tm [(a)] TJ ET EMC /P <</MCID 275 >> BDC BT 1 0 0 -1 28.66200066 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 276 >> BDC BT 1 0 0 -1 33.16199875 152.12199402 Tm [(mediat)1(or)] TJ ET EMC /P <</MCID 277 >> BDC BT 1 0 0 -1 72.33899689 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 278 >> BDC BT 1 0 0 -1 76.83899689 152.12199402 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <</MCID 279 >> BDC BT 1 0 0 -1 113.91100311 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 280 >> BDC BT 1 0 0 -1 118.41100311 152.12199402 Tm [(TGF)] TJ ET EMC /P <</MCID 281 >> BDC BT 1 0 0 -1 135.04400635 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 282 >> BDC BT 1 0 0 -1 139.54400635 152.12199402 Tm [(beta)] TJ ET EMC /P <</MCID 283 >> BDC BT 1 0 0 -1 158.72599792 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 284 >> BDC BT 1 0 0 -1 163.22599792 152.12199402 Tm [(rec)-1(ept)1(ors)] TJ ET EMC /P <</MCID 285 >> BDC BT 1 0 0 -1 203.81399536 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 286 >> BDC BT 1 0 0 -1 208.31399536 152.12199402 Tm [(and)] TJ ET EMC /P <</MCID 287 >> BDC BT 1 0 0 -1 224.59100342 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 288 >> BDC BT 1 0 0 -1 229.09100342 152.12199402 Tm [(TAK1.)] TJ ET EMC /P <</MCID 289 >> BDC BT 1 0 0 -1 253.74000549 152.12199402 Tm [( )] TJ ET EMC /P <</MCID 290 >> BDC BT 1 0 0 -1 258.23999023 152.12199402 Tm [(Thi)] TJ ET EMC /P <</MCID 291 >> BDC BT 1 0 0 -1 0 167.72200012 Tm [(s)] TJ ET EMC /P <</MCID 292 >> BDC BT 1 0 0 -1 4.16599989 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 293 >> BDC BT 1 0 0 -1 8.66600037 167.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <</MCID 294 >> BDC BT 1 0 0 -1 39.97299957 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 295 >> BDC BT 1 0 0 -1 44.47299957 167.72200012 Tm [(can)] TJ ET EMC /P <</MCID 296 >> BDC BT 1 0 0 -1 59.50699997 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 297 >> BDC BT 1 0 0 -1 64.00700378 167.72200012 Tm [(also)] TJ ET EMC /P <</MCID 298 >> BDC BT 1 0 0 -1 81.26399994 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 299 >> BDC BT 1 0 0 -1 85.76399994 167.72200012 Tm [(interact)] TJ ET EMC /P <</MCID 300 >> BDC BT 1 0 0 -1 118.44200134 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 301 >> BDC BT 1 0 0 -1 122.94200134 167.72200012 Tm [(wit)1(h)] TJ ET EMC /P <</MCID 302 >> BDC BT 1 0 0 -1 141.33799744 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 303 >> BDC BT 1 0 0 -1 145.83799744 167.72200012 Tm [(and)] TJ ET EMC /P <</MCID 304 >> BDC BT 1 0 0 -1 162.11500549 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 305 >> BDC BT 1 0 0 -1 166.61500549 167.72200012 Tm [(activat)1(e)] TJ ET EMC /P <</MCID 306 >> BDC BT 1 0 0 -1 200.00900269 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 307 >> BDC BT 1 0 0 -1 204.50900269 167.72200012 Tm [(th)1(e)] TJ ET EMC /P <</MCID 308 >> BDC BT 1 0 0 -1 218.50999451 167.72200012 Tm [( )] TJ ET EMC /P <</MCID 309 >> BDC BT 1 0 0 -1 223.00999451 167.72200012 Tm [(mito)1(gen)-1(-)1(a)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 143.55000305 0.75 m 143.55000305 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 172.3500061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 172.7250061 m 423.17498779 172.7250061 l S Q Q Q 1 0 0 -1 0 841.90002441 cm 
endstream
endobj
6 0 obj
<</Length1 123 0 R/Length 29324>>stream
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