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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1499939 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 85.46499634 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 157.22900391 23.67700005 Tm 0 Tr [(STAT6)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 219.39399719 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 329.83401489 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(ST)-1(A)1(T)-1(6)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 126.20500183 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 178.70500183 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.20500183 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(STAT6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.18800354 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.56199646 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.33399963 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.70799255 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.02900696 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.40299988 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.19900513 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(si)-1(g)1(n)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.41500092 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.8789978 12.82499981 Tm [(transdu)-1(ce)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.06799316 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.53199768 12.82499981 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.59500122 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.05900574 12.82499981 Tm [(activator)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.94200134 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.40600586 12.82499981 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.14700317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.61099243 12.82499981 Tm [(transcripti)-1(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.44900513 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 277.91299438 12.82499981 Tm [(6;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.04400635 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.50799561 12.82499981 Tm [(ST)-1(A)1(T)-1(6B)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 325.48400879 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 329.94799805 12.82499981 Tm [(ST)-1(A)1(T)-1(6C;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 364.81100464 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 369.2749939 12.82499981 Tm [(D12S1644;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29998779 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(IL-)-1(4)1(-)-1(STAT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.94400024 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.97299194 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ST)-1(A)1(T)-1(6)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.45500183 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 299.51199341 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.99199677 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 333.05099487 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 366.58999634 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.77200317 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.14600372 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.46699524 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 400.1289978 m 416.75 400.1289978 l 416.75 431.32901001 l -1.45000005 431.32901001 l h f* Q q 1 0 0 1 0 400.1289978 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 431.32901001 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 459.26800537 cm q /GS2 gs 1 g 0.375 0.75 m 131.17500305 0.75 l 131.17500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 132.17500305 -0.25 l 132.17500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 131.92500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 131.92500305 156.75 l h f* Q q 1 0 0 1 131.55000305 0 cm -0.625 -0.25 m 291.875 -0.25 l 291.875 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(STAT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.09298706 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.59298706 11.72200012 Tm [(f)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(amily)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.96100044 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.46100044 27.3220005 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.3030014 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.8030014 27.3220005 Tm [(tr)1(ansc)-1(rip)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.38700104 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.88700104 27.3220005 Tm [(fa)1(c)-1(t)1(ors.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.33900452 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 135.83900452 27.3220005 Tm [(In)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.02999878 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.52999878 27.3220005 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.5269928 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.0269928 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.102005 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.602005 27.3220005 Tm [(cy)-1(t)1(oki)-1(nes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.06700134 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.56700134 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.84399414 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.34399414 27.3220005 Tm [(gr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ow)1(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.72200012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.22200012 42.92200089 Tm [(fa)1(c)-1(t)1(ors,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.67399979 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.17399979 42.92200089 Tm [(STAT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.01899719 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.51899719 42.92200089 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.60099792 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.10099792 42.92200089 Tm [(members)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.53100586 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.03100586 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.54899597 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.04899597 42.92200089 Tm [(ph)1(osph)1(orylated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.02400208 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.52400208 42.92200089 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.03601074 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.53601074 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.5369873 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.42200089 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.92200089 58.52199936 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.0490036 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.5490036 58.52199936 Tm [(ki)-1(na)1(se)-1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.96900177 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.46899414 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.7460022 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.2460022 58.52199936 Tm [(th)1(e)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.79299927 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.29299927 58.52199936 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.0039978 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.5039978 58.52199936 Tm [(ho)1(mo-)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.81599426 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.31599426 58.52199936 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.47399902 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 245.97399902 58.52199936 Tm [(heterod)1(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(mers)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.1420002 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.6420002 74.12200165 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.86399841 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.36399841 74.12200165 Tm [(tr)1(ansloc)-1(a)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.90399933 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.40399933 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.47899628 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.97899628 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.98000336 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.47999573 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.88999939 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.38999939 74.12200165 Tm [(nuc)-1(leu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.20799255 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.70799255 74.12200165 Tm [(wh)1(e)-1(r)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.00500488 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.50500488 74.12200165 Tm [(th)1(e)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.27000427 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.77000427 74.12200165 Tm [(act)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.61099243 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 259.11099243 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.25201416 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.75201416 74.12200165 Tm [(tr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(anscript)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.79499817 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.29499817 89.72200012 Tm [(activat)1(ors.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.07299805 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.57299805 89.72200012 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.83499908 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.33499908 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.64199829 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.14199829 89.72200012 Tm [(plays)] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.18899536 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.68899536 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.66400146 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.16400146 89.72200012 Tm [(ce)-1(ntr)1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.48899841 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.98899841 89.72200012 Tm [(role)] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.64900208 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.14900208 89.72200012 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.08999634 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.58999634 89.72200012 Tm [(exe)-1(r)1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.69799995 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.19799995 105.3219986 Tm [(IL4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.73999977 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.24000168 105.3219986 Tm [(mediat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.12200165 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.62200165 105.3219986 Tm [(biolo)1(gic)-1(a)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.63800049 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.13800049 105.3219986 Tm [(responses.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.46800232 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 176.96800232 105.3219986 Tm [(It)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.96699524 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.46699524 105.3219986 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.02799988 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.52799988 105.3219986 Tm [(fo)1(u)-1(nd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.21800232 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.71800232 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.79299927 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.29299927 105.3219986 Tm [(induc)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.15600586 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.65600586 105.3219986 Tm [(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(he)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.64799976 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.14799976 120.92199707 Tm [(expression)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.10200119 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.60199738 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 74.44400024 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.94400024 120.92199707 Tm [(BCL)-1(2L1)-1(/BCL-X\(L\),)] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.03100586 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.53100586 120.92199707 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.62800598 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.12800598 120.92199707 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 193.68899536 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.18899536 120.92199707 Tm [(responsib)1(l)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.72399902 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.22399902 120.92199707 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.50201416 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.00201416 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.00299072 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(anti-)1(apo)1(pto)1(tic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.68999863 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.19000244 136.52200317 Tm [(activit)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.66200256 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.16200256 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.0039978 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.5039978 136.52200317 Tm [(IL4)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.21200562 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.71200562 136.52200317 Tm [(Knock)-1(o)1(u)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 174.72599792 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.22599792 136.52200317 Tm [(st)1(u)-1(d)1(ie)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.71499634 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.21499634 136.52200317 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.15600586 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.65600586 136.52200317 Tm [(mic)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.10400391 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.60400391 136.52200317 Tm [(sugg)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ted)] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.2159996 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.7159996 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.71699905 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.21699905 152.12199402 Tm [(roles)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.04299927 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.54299927 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.38500214 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.88500214 152.12199402 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.34100342 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.84100342 152.12199402 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.35700226 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.85700226 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.79800415 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.29800415 152.12199402 Tm [(dif)1(fe)-1(r)1(e)-1(nt)1(i)-1(a)1(tion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.62399292 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.12399292 152.12199402 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 208.96600342 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 213.46600342 152.12199402 Tm [(T)] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.625 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 223.125 152.12199402 Tm [(helper)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.45899963 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.95899963 152.12199402 Tm [(2)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.23699951 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.73699951 152.12199402 Tm [(\(Th2)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 131.55000305 0.75 m 131.55000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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