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1 0 0 -1 0 841.90002441 cm /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 103.5 l -90 103.5 l h W n BT /FAAAAH 9 Tf 1 0 0 -1 0 92.5 Tm 0 g [( )] TJ ET q 1 0 0 1 9 1 cm q 270.1499939 0 0 -90.15000153 0 90.15000153 cm /X1 Do Q Q Q EMC q 1 0 0 1 90 146.05000305 cm /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 85.46499634 23.67700005 Tm 2 Tr 0 g 0.62857145 w 0 G [<0003>-4<0004>-4<0005>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 157.22900391 23.67700005 Tm 0 Tr [(STAT1)] TJ ET EMC /P <> BDC BT /FAAABB 22 Tf 1 0 0 -1 219.39399719 23.67700005 Tm 2 Tr [<0006>-4<0007>-4<0008>-4<0005>-4<0009>] TJ ET EMC /P <> BDC BT /FAAABG 22 Tf 1 0 0 -1 329.83401489 23.67700005 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 46.79999924 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000A000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm [<000300040005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 97.125 12.82499981 Tm [(ST)-1(A)1(T)-1(1)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 126.20500183 12.82499981 Tm [<00060007000800050009>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 178.70500183 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.45500183 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 80.33899689 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000F000B000C000D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Anti-)-1(STAT1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.18800354 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.56199646 12.82499981 Tm [(mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.33399963 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.70799255 12.82499981 Tm [(mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.02900696 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 196.40299988 12.82499981 Tm [(anti)-1(bo)-1(dy)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.19900513 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 113.87799835 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<000C000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(si)-1(g)1(n)-1(al)] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.41500092 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.22699738 12.82499981 Tm [(transdu)-1(ce)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.41600037 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 143.22799683 12.82499981 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.29100037 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.10299683 12.82499981 Tm [(activator)] TJ ET EMC /P <> BDC BT 1 0 0 -1 201.98599243 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 206.79800415 12.82499981 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.53900146 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.35099792 12.82499981 Tm [(transcripti)-1(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.18899536 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.00100708 12.82499981 Tm [(1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.13198853 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.94400024 12.82499981 Tm [(CAN)1(D)-1(F7;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 330.81201172 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 335.62399292 12.82499981 Tm [(IMD31A)1(;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 373.23498535 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 378.04699707 12.82499981 Tm [(IMD31B;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 415.29400635 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 30.49699783 Tm [(IMD31C;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.13499832 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.50899887 30.49699783 Tm [(ISGF)-1(-3;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.77300262 30.49699783 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.14700317 30.49699783 Tm [(ST)-1(A)1(T)-1(91)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.9240036 30.49699783 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 165.35600281 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011001200130010000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00140005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 198.89500427 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0015>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0016000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001700180019>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 232.43400574 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001D000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 265.97299194 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0005>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<001E000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ST)-1(A)1(T)-1(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 89.45500183 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 299.51199341 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001F002000210022000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Human)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.61199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.98600006 12.82499981 Tm [(Mon)-1(k)1(ey)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.76699829 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 333.05099487 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0023>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 15.75 12.82499981 Tm [<0024>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 26.25 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 31.5 12.82499981 Tm [<0025000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Uncon)-1(jugate)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.48899841 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 366.58999634 cm /P <> BDC BT /FAAABJ 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0007000800130026000E>] TJ ET EMC /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(Mou)-1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.36199951 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.73600006 12.82499981 Tm [(Mon)-1(oclo)-1(nal)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.64700317 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q /GS2 gs 1 g -1.45000005 400.1289978 m 416.75 400.1289978 l 416.75 431.32901001 l -1.45000005 431.32901001 l h f* Q q 1 0 0 1 0 400.1289978 cm /P <> BDC q /GS2 gs 1 g 0 6.59399986 m 42 6.59399986 l 42 24.60499954 l 0 24.60499954 l h f* Q EMC /P <> BDC BT /FAAACF 10.5 Tf 1 0 0 -1 0 20.17499924 Tm /GS2 gs 0.13333334 g [<0003000400050006>] TJ ET EMC /P <> BDC BT /FAAACJ 10.5 Tf 1 0 0 -1 42 20.17499924 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 431.32901001 cm /P <> BDC BT /FAAAAH 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 459.26800537 cm q /GS2 gs 1 g 0.375 0.75 m 140.17500305 0.75 l 140.17500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 141.17500305 -0.25 l 141.17500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 140.92500305 0.75 m 422.42498779 0.75 l 422.42498779 156.75 l 140.92500305 156.75 l h f* Q q 1 0 0 1 140.55000305 0 cm -0.625 -0.25 m 282.875 -0.25 l 282.875 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAADC 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.80700016 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.30699921 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.61399841 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.11399841 11.72200012 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.6210022 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.1210022 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.63300323 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.13300323 11.72200012 Tm [(th)1(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.58900452 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.08900452 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.10499573 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.66600037 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.16600037 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.14100647 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.64100647 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.90499878 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.40499878 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.24699402 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.74699402 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.7480011 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.2480011 11.72200012 Tm [(STAT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.09298706 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.30699921 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.80699921 27.3220005 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.05500031 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.55500031 27.3220005 Tm [(In)] TJ ET EMC /P <> BDC BT 1 0 0 -1 76.7460022 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.2460022 27.3220005 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.24299622 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.74299622 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.81799316 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.31799316 27.3220005 Tm [(cy)-1(t)1(oki)-1(nes)] TJ ET EMC /P <> BDC BT 1 0 0 -1 178.78300476 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.28300476 27.3220005 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.55999756 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.05999756 27.3220005 Tm [(gr)1(owt)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.97599792 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.47599792 27.3220005 Tm [(fa)1(c)-1(t)1(ors,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.92800903 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(STAT)] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.84499931 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.34499931 42.92200089 Tm [(fa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.42699814 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.92699814 42.92200089 Tm [(members)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.35700226 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.85700226 42.92200089 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.375 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.875 42.92200089 Tm [(ph)1(osph)1(orylated)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.8500061 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.3500061 42.92200089 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.86199951 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.36199951 42.92200089 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.36300659 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.86300659 42.92200089 Tm [(rec)-1(ept)1(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.28500366 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.78500366 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ssociat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.15299988 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.65299988 58.52199936 Tm [(ki)-1(na)1(se)-1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.07299805 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.57299805 58.52199936 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.84999847 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.34999847 58.52199936 Tm [(th)1(e)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.89700317 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.39700317 58.52199936 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.10800171 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.60800171 58.52199936 Tm [(ho)1(mo-)] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.91999817 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.41999817 58.52199936 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.57800293 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.07800293 58.52199936 Tm [(heterod)1(ime)-1(rs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.63800049 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.13800049 58.52199936 Tm [(th)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.32800007 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.82800007 74.12200165 Tm [(tr)1(ansloc)-1(a)1(te)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.36800003 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.86799622 74.12200165 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.94300079 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 78.44300079 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.44400024 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.94400024 74.12200165 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.35399628 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.85399628 74.12200165 Tm [(nuc)-1(leu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.67199707 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 153.17199707 74.12200165 Tm [(wh)1(e)-1(r)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.46899414 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.96899414 74.12200165 Tm [(th)1(e)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.73399353 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.23399353 74.12200165 Tm [(act)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.07499695 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.57499695 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.71600342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.21600342 74.12200165 Tm [(tr)1(ansc)-1(ri)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(pt)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.76399994 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.26399994 89.72200012 Tm [(activat)1(ors.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.04199982 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.54199982 89.72200012 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.80400085 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.30400085 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.61099243 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.11099243 89.72200012 Tm [(can)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.14500427 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.64500427 89.72200012 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.49899292 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.99899292 89.72200012 Tm [(activat)1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.1499939 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 211.6499939 89.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.16200256 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.66200256 89.72200012 Tm [(var)1(i)-1(o)1(u)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.62600708 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.12600708 89.72200012 Tm [(lig)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(ands)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.44300079 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.94300079 105.3219986 Tm [(inc)-1(luding)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.79299927 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.29299927 105.3219986 Tm [(interferon-a)1(lpha,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.7539978 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.2539978 105.3219986 Tm [(interferon-g)1(amma,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.65400696 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.15400696 105.3219986 Tm [(EG)1(F)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.74299622 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 255.24299622 105.3219986 Tm [(PDG)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(F)] TJ ET EMC /P <> BDC BT 1 0 0 -1 4.78100014 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 9.28100014 120.92199707 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.55800056 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.05800056 120.92199707 Tm [(IL6)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.76599884 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.26599884 120.92199707 Tm [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.52799988 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.02799988 120.92199707 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 102.33499908 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.83499908 120.92199707 Tm [(mediat)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 146.1269989 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.6269989 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.62800598 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.12800598 120.92199707 Tm [(expression)] TJ ET EMC /P <> BDC BT 1 0 0 -1 215.08200073 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.58200073 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.42399597 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.92399597 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.89900208 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.39900208 120.92199707 Tm [(var)1(i)-1(ety)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.15200806 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 136.52200317 Tm [(gene)-1(s,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.18999863 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.68999863 136.52200317 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.78700256 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.28700256 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.84799957 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.34799957 136.52200317 Tm [(th)1(ought)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.16100311 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.66100311 136.52200317 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.73599243 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 139.23599243 136.52200317 Tm [(be)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.08999634 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.58999634 136.52200317 Tm [(impor)1(tant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.55099487 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.05099487 136.52200317 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.32899475 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 218.82899475 136.52200317 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 233.23899841 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.73899841 136.52200317 Tm [(viab)1(i)-1(lit)1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.88299561 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 7.94099998 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 12.44099998 152.12199402 Tm [(response)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.43799973 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.93799973 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.01300049 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.51300049 152.12199402 Tm [(dif)1(fe)-1(r)1(e)-1(nt)] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.45300293 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.95300293 152.12199402 Tm [(ce)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 125.36299896 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.86300659 152.12199402 Tm [(st)1(i)-1(muli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 158.54600525 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.04600525 152.12199402 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.32299805 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.82299805 152.12199402 Tm [(pa)1(tho)1(gen)-1(s.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 231.90400696 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.40400696 152.12199402 Tm [(Two)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.39100647 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.89099121 152.12199402 Tm [(alt)1(e)] TJ ET EMC Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 140.55000305 0.75 m 140.55000305 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 422.79998779 0.75 m 422.79998779 156.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 423.17498779 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 157.125 m 423.17498779 157.125 l S Q Q Q 1 0 0 -1 0 841.90002441 cm
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